• 제목/요약/키워드: antioxidant substances

검색결과 552건 처리시간 0.025초

Phytotoxic Effect, DPPH Radical Scavenging Activity and Chlorogenic Acid Level of Methanol Extracts from Aerial Parts of Several Korean Salad Plants

  • Chon Sang-Uk;Kim Young-Min;Kim Dong-Kwan;Heo Buk-Gu;Cho Ja-Yong
    • 한국자원식물학회지
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    • 제19권3호
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    • pp.405-410
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    • 2006
  • A series of aqueous or methanol extracts from four different Korean salad plants were assayed to determine their allelopathy and antioxidant activity. The extracts applied on filter paper in a Petri-dish bioassay significantly inhibited root growth of against alfalfa (Medicago sativa) seedlings. Leaf extracts from 40 g dry tissue $L^{-1}$ of Aster yomena was most phytotoxic to alfalfa root growth, and followed by that of Cirsium japonicum, Taraxacum officinale, and Ixeris dentate. Methanol extracts of plants dose-dependently increased DPPH free radical scavenging activity in vitro. Antioxidant activity of methanol extracts from the same plant species was investigated, and the result showed high DPPH free radical scavenging activity in Cirsium japonicum, Aster yomena, and Ixeris dentate, however, in Taraxacum officinale was least activity. By means of HPLC analysis, chlorogenic acid, p-coumaric acid, and total phenolics with 7.68, 17.47 and 18.64 mg, $100g^{-1}$, respectively, showed the highest amounts in methanol extracts from Cirsium japonicum leaves. These results suggest that Compositae salad plants contain water-soluble substances with allelopathic potential as well as antioxidant activity.

Anti-inflammatory, Antioxidant and Antimicrobial Effects of Artemisinin Extracts from Artemisia annua L.

  • Kim, Wan-Su;Choi, Woo Jin;Lee, Sunwoo;Kim, Woo Joong;Lee, Dong Chae;Sohn, Uy Dong;Shin, Hyoung-Shik;Kim, Wonyong
    • The Korean Journal of Physiology and Pharmacology
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    • 제19권1호
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    • pp.21-27
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    • 2015
  • The anti-inflammatory, antioxidant, and antimicrobial properties of artemisinin derived from water, methanol, ethanol, or acetone extracts of Artemisia annua L. were evaluated. All 4 artemisinin-containing extracts had anti-inflammatory effects. Of these, the acetone extract had the greatest inhibitory effect on lipopolysaccharide-induced nitric oxide (NO), prostaglandin $E_2$ ($PGE_2$), and proinflammatory cytokine ($IL-1{\beta}$, IL-6, and IL-10) production. Antioxidant activity evaluations revealed that the ethanol extract had the highest free radical scavenging activity, ($91.0{\pm}3.2%$), similar to ${\alpha}$-tocopherol (99.9%). The extracts had antimicrobial activity against the periodontopathic microorganisms Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum subsp. animalis, Fusobacterium nucleatum subsp. polymorphum, and Prevotella intermedia. This study shows that Artemisia annua L. extracts contain anti-inflammatory, antioxidant, and antimicrobial substances and should be considered for use in pharmaceutical products for the treatment of dental diseases.

피혁 폐기물을 재활용한 재생가죽의 내노화특성 연구 (A Study on Anti-Aging Properties of Recycled Leather Using Shaving Scrap by Applying Antioxidant)

  • 서은호;임성욱;이윤섭;김원주;박은영
    • 한국염색가공학회지
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    • 제35권3호
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    • pp.151-158
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    • 2023
  • In this study, we investigated the durability properties of the recycled leather using shaving scrap with antioxidant. Recycled leather sheets were manufactured by mixing shaving scrap and NB latex as a binder. HALS(Hindered Amine Light Stabilizer) and UVA(UV absorbers) were used as antioxidant. Mechanical properties such as hardness, tensile strength, elongation, tear strength and abrasion resistance were measured. Light aging resistance was evaluated using UV lamp and the degree of discoloration of the recycled leather sheets using a gray scale. In addition, to evaluate heat aging and UV aging, the degree of discoloration of the recycled leather sheets over time was measured using colorimeter. Washing fastness was evaluated on the degree of dyeing of recycled leather sheets for six type of multi-fiber woven fabrics (Acetate, Cotton, Nylon-66, Polyester, Acryl, Wool). To determine whether hazardous substances were detected in recycled leather sheets, the contents of arylamine and Cr 6+ were evaluated. As a result, when used in combination with antioxidant, the heat aging and light aging of recycled leather were improved and hazardous substance were not detected.

Cholesterol-lowering Efficacy of Unrefined Bran Oil from the Pigmented Black Rice (Oryza sativa L cv. Suwon 415) in Hypercholesterolemic Rats

  • Nam, Yean-Ju;Nam, Seok-Hyun;Kang, Mi-Young
    • Food Science and Biotechnology
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    • 제17권3호
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    • pp.457-463
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    • 2008
  • The effects of dietary supplementation of the unrefined rice bran oil from 'Suwon 415' pigmented black rice (BRBO) on cholesterol metabolism and cellular antioxidant status were investigated in hypercholesterolemic rats. The significant reduction of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) concentrations was observed in the plasma of rats fed BRBO. BRBO also decreased plasma and hepatic oxidative stress as a result of increased levels of hepatic thiobarbituric acid reactive substances (TBARS) levels associated with the elevations of hepatic superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities together with increased plasma level of tocopherol. This study indicates that dietary BRBO supplement can leads to the improvement of overall cholesterol metabolism and antioxidant status even more effectively than 'Chuchung' white rice (WRBO). Consumption of BRBO may also protect the liver from oxidative damage caused by lipid peroxidation.

삼황사심탕약침의 지질강하 및 항산화효과 (Antihyperlipidemic and antioxidant effects of Samhwangsasimtang aqua-acupuncture)

  • 이은;이준무
    • 대한약침학회지
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    • 제8권1호
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    • pp.51-57
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    • 2005
  • Effects of Samhwangsasimtang aqua-acupuncture at gansoo($B_{18}$) and chungwan($CV_{12}$) on antihyperlipidemic and antioxidant were investigated in rat fed high fat diet. Concentrations of triglyceride, free fatty acids, lipoprotein and glucose in plasma showed a tendency to decrease in the aqua-acupuncture groups. In plasma lipid composition, total cholesterol and LDL- cholesterol showed a tendency to decrease in aqua-acupuncture groups, however the values of HDL-cholesterol showed no significantly different in the treatment groups. Concentration of thiobarbituric acid reactive substances(TBARS) in plasma and liver showed a low in the aqua-acupuncture groups. The values of glutathione peroxidase(GSH-Px) and catalase(CAT) activity showed a tendency to increase in aqua-acupuncture groups. However the values of superoxide dismutase(SOD) activity showed no significantly different in the treatment groups.

Antioxidants from macroalgae: potential applications in human health and nutrition

  • Cornish, M. Lynn;Garbary, David J.
    • ALGAE
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    • 제25권4호
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    • pp.155-171
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    • 2010
  • The underlying physiology of algal antioxidant compounds is reviewed in the context of seaweed biology and utilization. The application of seaweed antioxidants in foods, food supplements, nutraceuticals and medicine is considered from the perspective of benefits to human health. We advocate that direct consumption of seaweed products for their antioxidant composition alone provides a useful alternative to non-natural substances, while simultaneously providing worthwhile nutritional benefits. Economic utilization of seaweeds for their antioxidant properties remains in its infancy. This review provides examples ranging from laboratory studies through to clinical trials where antioxidants derived from seaweeds may provide major health benefits that warrant subsequent investigative studies and possible utilization.

허혈성심질환에서의 항산화영양소 상태와 혈소판 항산화계효소 활성에 관한 연구 (Plasma Antioxidant Status and Platelet Antionxidative Enzyme Activities in Patients of Ischemic Heart Disease)

  • 최영선
    • Journal of Nutrition and Health
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    • 제29권2호
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    • pp.223-231
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    • 1996
  • To investigate antioxidant status and platelet antioxidative enzyme activity in patients with ischemic heart disease, 36 male patients admitted to Kyungpook National University Hospital from June to December 1994 were compared to 36 healthy male control subjects. The percentages of heavy smoking and nonexercise were significantly higher in the patient group compared to the control, but the drinking status was not significantly different between groups. Food habit and food frequency scores were significantly lower in patients than in control subjects. Plasma retinol levels tended to be lower in the patient group, and plasma $\alpha$-tocopherol and $\beta$-carotene levels were not different between groups. There was no difference in the level of plasma thiobarbituric acid reactive substances(TBARS) and in the activities of platelet glutathione peroxidase and catalase. Our results indicate that oxidative stress, which is reflected by the plasma levels of antioxidants and TBARS, did not increase in the patients with ischemic heart disease, and the long-term effects due to smoking, poor food habit and other life styles could possibly contribute to the onset of the disease.

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Action of Asparagus racemosus Against Streptozotocin-Induced Oxidative Stress

  • Govindarajan, Raghavan;Vijayakumar, Madhavan;Rao, Chandana Venkateshwara;Kumar, Vivek;Rawat, Ajay Kumar Singh;Pushpangadan, Palpu
    • Natural Product Sciences
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    • 제10권4호
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    • pp.177-181
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    • 2004
  • Antidiabetic treatment with tubers of Asparagus racemosus (Liliaceae) extract (l00 and 250 mg/kg body weight) for three weeks showed significant reduction in thiobarbituric acid reactive substances (TBARS) and glutathione reductase (GSH-R) in both liver and kidney. The treatment with A. racemosus significantly altered the glutathione (GSH) and GSH-R to be comparable with the control group. A. racemosus and glibenclamide treated rats showed decreased lipid peroxidation that is associated with increased activity of superoxide dismutase (SOD) and Catalase (CAT). The ability of A. racemosus on tissue lipid per oxidation and antioxidant status in diabetic animals has not been studied before. The result of this study thus shows that though, A. racemosus possesses moderate antidiabetic activity, but it exhibits potent antioxidant potential in diabetic conditions.

채취 시기에 따른 와송 추출물의 항상화 활성 연구 (Studies on the Antioxidative Ability of Methanol and Water Extracts from Orostachys japonicus A. Berger According to Harvest Times)

  • 최선영;정미자;성낙주
    • 한국식품영양학회지
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    • 제21권2호
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    • pp.157-164
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    • 2008
  • This study examined the antioxidant activity of methanol and water extracts from Orostachys japonicus A. Berger according to harvest times, by measuring electron donating ability(EDA), reducing power, superoxide dismutase(SOD)-like activity, thiobarbituric acid reactive substances(TBARS) and antioxidant activity within a linoleic acid emulsion. EDA increased proportionally with the extract concentration and the methanol extract had slightly stronger effects than the water extract. And reducing power and SOD-like activity were highest in the methanol extract. Overall, based on the data, the methanol extract of O. japonicus A. Berger harvested during $August{\sim}October$ presented the highest level of antioxidative activity and may be a good candidate as a natural antioxidant source.

매실씨 부산폐기물의 항산화 기능 (Antioxidant Activity of Prunus mume Extract in Cooked Chicken Breast Meat)

  • 이승철
    • 한국식품저장유통학회:학술대회논문집
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    • 한국식품저장유통학회 2005년도 매실관련 학술 세미나
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    • pp.17-26
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    • 2005
  • The antioxidant properties of methanolic extracts from the fruit of Prunus mume were determined in chicken breast meat systems. When P. mume extract (PM) was added to chicken breast meat, 2-thiobarbituric acid-reactive substances (TBARS) value at Day 3 was decreased by about $45\%$ of the control. PM did not affect color of chicken meat compared to the control. The amounts of volatile aldehydes and hydrocarbons were significantly decreased by the addition of PH. Especially, hexanal was the most predominant volatile compound in the control taking up almost more than $50\%$ of the total volatiles, and PM reduced the amount into $26\%$ of the control meat at 3 days.

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