• Title/Summary/Keyword: anti-cathartic

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백편두(白扁豆), 가자(訶子) 및 보장건비탕(補腸健脾湯)의 항사하작용(抗瀉下作用)에 관(關)한 연구(硏究) (Experimental Studies on the Anti-cathartic Effects of Dolichoris Semen, Terminaliae Fructus and Bojanggunbi-tang)

  • 노우성;김진성;윤상협;류봉하
    • 대한한방내과학회지
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    • 제27권2호
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    • pp.356-370
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    • 2006
  • Objectives: The aim of this experimental study is to investigate effects of Dolichoris Semen, Terminaliae Fructus and Bojanggunbi-tangon the anti-cathartic action of mice and guinea pigs to develop effective herbal medicine and prescription to cure diarrhea early and to prevent side effect of chronic diarrhea. Methods: To compare effects of Dolichoris Semen, Terminaliae Fructus and Bojanggunbi-tangon the anti-cathartic action of mice and guinea pigs, we evaluated the actions on isolated gastrointestinal smooth muscles. on the transportability of small and large intestines, onthe neostigmine-induced transportability of small intestine and on diarrhea induced by castor oil, pilocarpine, barium chloride. Results: (1) Dolichoris Semen, Terminaliae Fructus and Bojanggunbi-tang showed the strong alleviation on the contraction of mice's isolated gastrointestinal smooth muscles induced by acetylcholine chloride and barium chloride. while Terminaliae Fructus, strong, Bojanggunbi-tang, intermediate and Dolichoris Semenshowed the minor alleviation on the contraction of guinea pigs' isolated gastrointestinal smooth muscles induced by acetylcholine chloride and histamine. All effects depended on the density in each medicine. (2) The tranbportability of small intestine was contrained in the groups controlled by 600 mg/kg of Dolichoris Semen, Terminaliae Fructus and Bojanggunbi-tang, and 200 mg/kg of D olichoris Semen and Terminaliae Fructus. However, the enhancement of neostigmine-induced transportability of small intestine was constrained only in the groups controlled by 600 mg/kg of Dolichoris Semen, Terminaliae Fructus and Boianggunbi-tang. (3) The transportability of large intestine was constrained by Dolichoris Semen and Bojanggunbi-tang. They showed substantial results. which depended on the amount of each medicine. (4) Terminaliae Fructus showed substantial anti-cathartic effects on diarrhea induced by caster oil in both groups controlled by 200 and 600 mg/kg of it. However, Bojanggunbi-tangshowed the effects only in the group controlled by 600 mg/kg. in diarrhea induced by pilocarpine, the groups controlled by 600 mg/kg or Terminaliae Fructus and 200 and 600 mg/kg of Boianggnbi-tangshowed substantial results. In diarrhea induced by barium chloride. the groups controlled by 200 and 600 mg/kg of Terminaliae Fructus and 600 mg/kg of Boianggunbi-tangshowed substantial results in anti-cathartic effects. Conclusions: These results show that Terminaliae Fructus is more effective on the contraction of mice and guinea pigs' isolated gastrointestinal smooth muscles, Dolichoris Semen is more effective on the transportability of small intestine, Dolichoris Semen and Bojanggunbi-tang are more effective on the transportability of large intestine. Terminaliae Fructus and Bojanggunbi-tang show substantial results in anti-cathartic actions.

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생약복합제제(生藥複合製劑)의 약효연구(藥效硏究) (제42보(第42報)) -지출탕(枳朮湯)이 적출평활근(摘出平滑筋) 및 소화기계(消化器系)에 대한 작용- (Studies on the Efficacy of Combined Preparation of Crude Drug (XLII) -Effects of Chichul-Tang on Gastrointestinal Tract and Smooth Muscle-)

  • 홍남두;장인규;김남재;김진식;장국성
    • 생약학회지
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    • 제21권4호
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    • pp.300-306
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    • 1990
  • Chichul-Tang, a combined preparation of crude drug, which was composed of Atractylodis Rhizoma alba and Ponciri Fructus, has been used widely for digestive disorder. Each herb extract of Atractylodis Rhizoma and Ponciri Fructus, the mixture of both herb extracts were examined for the effects on isolated smooth muscle, intestinal propulsion, anti-cathartic action and gastric secretion. The results were summarized as follows: Chichul-Tang showed the inhibitory effects of the convulsion of smooth muscle. Anti-cathartic effect was shown and gastric secretion was inhibited.

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보장지사탕의 항사하작용에 관한 연구 (Experimental Studies on the Anti-cathartic Effects of Bojangjisa-tang)

  • 이선령;박재우;류봉하
    • 대한한방내과학회지
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    • 제28권2호
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    • pp.217-229
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    • 2007
  • Objectives : The aim of this experimental study was to investigate the effects of Bojangjisa-tang on anticatharsis by using mice and Guinea pigs. Methods : We observed the actions on gastrointestinal smooth muscles, on the transportability of small and large intestines and on diarrhea induced by castor oil, philocarpine, and barium chloride. Results : Bojangjisa-tang showed alleviation of the contraction of gastrointestinal smooth muscles induced by acetylcholine chloride and barium chloride. The transportability of the large intestine was constrained by Bojangjisa-tang, which also showed substantial anti-cathartic effects on diarrhea induced by castor oil, philocarpine and barium chloride. Conclusion : These results demostrate that Bojangjisa-tang has advantageous effects on drug-induced diarrhea and will contribute to the development of diarrhea treatment through further related studies.

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실장산(實腸散)이 위장관(胃腸管)에 미치는 영향(影響) (Experimental studies on the efficacy of Siljangsan)

  • 공현식;유봉하;박동원;유기원
    • 대한한방내과학회지
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    • 제15권2호
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    • pp.197-208
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    • 1994
  • In order to investigate the efficacy of Siljangsan by using the experimental animals, the action of gastric juice secretion, antiulcer. transport rates in the intestine and anti-cathartic action were studied. The following results were obtained. 1. Preventive effects on ulcer induced by pylorus-ligated and Ethanol-HCI were recognized 2. Suppression effects on gastric juice secretinon, free of acidity and total acidity were recognized, but pepsin output was not recognized. 3. For the transport ability of intestine of mice, the ability of small intestine was activated and large intestine was suppressed in the group administrated 4. Anti-cathatic action of mice induced by castor oil was recognized. According to above results, effect based on oriental medical reference was consistent with the actual experimental effect.

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불환금정기산(不換金正氣散)의 효능(效能)에 관(關)한 실험적(實驗的) 연구(硏究) (An experimental research of the efficancy of Boolwhangumjeonggisan)

  • 임성우;류봉하;박동원;장인규;류기원
    • 대한한방내과학회지
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    • 제11권1호
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    • pp.15-27
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    • 1990
  • For the purpose of examing on the efficancy of the Boolwhangumjeonggisan and on the effect of the Boolwhangumjeonggisan, dropsy animals given water boil ding abstraction exgis power. What made an experiment, the motility of isolate ileume, anticathartic action, the action of gastric juice, tied pylous ulcer and inhibited vomitting. 1. Boolwhangumjeonggisan displayed great suppresion effect in regard to automatic movement of the motility of isolated of mice and displayed anti-acethylcholine action, antibarium chloride action. Thus, the origin of muscle relaxation for internal smooth muscle is admitted. 2. It displayed great rexation effect in regard to fraction of rat's stomach and displayed contentional effect in regard to a cetylcholine and barium chloride. 3. It decreased rat of barium sulfate transport through the small intestine of mice. 4. It recognized anti-cathartic action, rat suffered from leading diarrhea by caster oil. 5. Total activity, pepsin secretion decreased and increased the pH of stomach in Shay's method. 6. It recognized powerful prevention effect on tied pylous ulcer. 7. It inhibited vomitting by administration of CuSo4 in frog.

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타이포그래피를 이용한 현대패션의 유형과 미적 특성 (Pattern and Aesthetic Characteristics of Modem Fashion using Typography)

  • 김선영
    • 복식문화연구
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    • 제17권2호
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    • pp.283-295
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    • 2009
  • This research covers the ways in which typography, which has been expressed in a diverse range of fields and changed communication functions from the era of reading to the era of feeling according to the change in the times and social demands, has been represented in modem fashion, along with examining its inherent aesthetic characteristics. I reviewed the general information of typography's fundamental notions and functions through documented records, and analyzed the inherent aesthetic characteristics by examining the typographical patterns shown in modem fashion based on art works in domestic and international collections after 2000. The result of this research is that typography in modem fashion has been used for improving brand image, expressing social slogans, expressing images, linguistic function for playful expression and the interdependent relationships of modeling functions. Typography in modem fashion has always been diversely expressed harmoniously with linguistic and modeling functions. Through this, the aesthetic characteristics were firstly parodies through direct sentences addressing political and social ideologies, economic gaps, environmental issues and anti-war protests. Secondly, by using brand logos, typography was used as a commercial means like brand-image transfer and separation through customization of other brands. Thirdly, the aesthetic and artistic value of fashion were expressed after being used as experimental visual components like image, motive and patterns which are all elements of fashion design. Fourthly, by distortion and transformation of characters or childish decorations, along with the harmonization of words, cathartic humor was provided for the calloused senses of modern people.

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