• 한국언어정보학회지:언어와정보
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• 제16권2호
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• pp.17-42
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• 2012

The issues of compositionality, materialized ever since Frege (1982), are critically re-examined in language first mainly and then in all other possible representational systems such as thoughts, concept combination, computing, gesture, music, and animal cognition. The notion is regarded as necessary and suggested as neurologically correlated in humans, even if a weakened version is applicable because of non-articulated constituents and contextuality. Compositionality is crucially involved in all linguistically or non-linguistically meaningful expressions, dealing with at-issue content, default content, and even not-at-issue meanings such as implicatures and presuppositions in discourse. It is a constantly guiding principle to show the relation between representation and mind, still posing tantalizing research issues.

• 생명과학회지
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• 제19권5호
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• pp.688-691
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• 2009

The methanol extract of muskmelon (Cucumis melo) has been investigated for its cognition enhancing effects by evaluation of inhibitory activities on acetylcholinesterase, a degrading enzyme of acetylcholine, a brain neurotransmitter, and ${\beta}$- secretase, which forms the ${\beta}$-amyloid toxic protein from its precursor protein. A passive avoidance task, one of the animal model experiments for learning and memory, was also performed. As a result, the melon extract showed 15.8% and 35.3% inhibition on acetylcholinesterase and ${\beta}$-secretase, respectively, with a final concentration of 100 mg/ml. In the animal model test, melon extract significantly (p<0.05) lengthened the step-through latency time by 22.7% compared to the control group, suggesting that melon extract has, indeed, an effect on cognition enhancement.

• International Journal of Computer Science & Network Security
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• 제23권2호
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• pp.47-54
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• 2023

This article reviews recent advances and perspectives in neuroscience related to consciousness, cognition, and neural networks in the brain. The neural mechanisms underlying cognitive processes, such as perception, attention, memory, and decision-making, are explored. The article also examines how these processes give rise to our experience of consciousness. The implications of these findings for our understanding of the brain and its functions are presented, as well as potential applications of this knowledge in fields such as medicine, psychology, and artificial intelligence. Additionally, the article explores the concept of a quantum viewpoint concerning consciousness, cognition, and creativity and how incorporating DNA as a key element could reconcile classical and quantum perspectives on human behaviour, consciousness, and cognition, as explained by genomic psychological theory. Furthermore, the article explains how the human brain processes external stimuli through the sensory nervous system and how it can be simulated using an artificial neural network (ANN) consisting of one input layer, multiple hidden layers, and an output layer. The law of learning is also discussed, explaining how ANNs work and how the modification of weight values affects the output and input values. The article concludes with a discussion of future research directions in this field, highlighting the potential for further discoveries and advancements in our understanding of the brain and its functions.

• 한국환경과학회지
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• 제22권6호
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• pp.679-686
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• 2013

Based on the survey of East Lake Park, South Lake Park and Tian Waicun in Tai'an by questionnaire survey, on-the-spot investigation and in-depth interview, the paper analyzes the tendencies of visitors to the animal elements and animal landscape in landscape architecture from three terms: primary attributes, the cognition of animal elements and animal elements landscape preferences. We have drawn several conclusions: the landscapes of animal elements are in urgent demand by the public ; The animal elements having lovely image, auspicious meaning and local characteristics are the most popular application types of animal elements landscapes ; The most favorite types of animals and animal elements are: doves, cranes monkeys, pandas, butterflies, dragonflies, fold fish, dolphins, dragons and cartoon animals ; The popular landscaping techniques of animal elements are the methods of combining with plants, buildings and garden ornaments.

• Progress in Superconductivity
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• 제13권1호
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• pp.18-23
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• 2011

We developed a four-channel first order gradiometer system to measure magnetoencephalogram for mice. We used double relaxation oscillation SQUID (DROS). The diameter of the pickup coil is 4 mm and the distance between the coils is 5 mm. Coil distance was designed to have good spatial resolution for a small mouse brain. We evaluated the current dipole localization confidence region for a mouse brain, using the spherical conductor model. The white noise of the measurement system was about 30 fT/$Hz^{1/2}$/cm when measured in a magnetically shielded room. We measured magnetic signal from a phantom having the same size of a mouse brain, which was filled with 0.9% saline solution. The results suggest that the developed system has a feasibility to study the functions of brain of small animals.

• 한국식품영양과학회지
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• 제31권6호
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• pp.1026-1034
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• 2002

청소년들의 칼슘에 대한 인식 및 섭취실태를 파악하기 위하여 부산시내 초등학교 6학년 145명, 고등학교 2학년 140명, 총 295명을 대상으로 이들의 칼슘에 대한 인식 및 섭취실태를 설문 및 식이섭취조사 방법을 통하여 조사하였다. 연구결과, 청소년들은 칼슘과 우유의 기능, 골다공증과 칼슘과의 관계는 잘 인식하고 있었으나, 칼슘의 흡수와 관련이 있는 영양소에 대해서는 인식이 낮은 것으로 나타났다. 칼슘에 대한 인식의 정도는 여학생들이 높은 점수를 얻었으며 초등학교 남학생에서 가장 낮은 점수를 나타내었다. 칼슘식품에 대한 기호도는 아이스크림, 김, 요구르트 순으로 높았으나 콩 및 뱅어포 등은 낮은 것으로 나타났으며, 연령 및 성별에 따라 좋아하는 정도가 달랐다. 청소년들의 하루 평균 칼슘 섭취량은 여학생에서 491.51~530.5 mg, 남학생이 554.5~636.7 mg이었으며 이는 한국인 영양권장량의 각각61.4~66.3%, 69.3~70.7%의 범위를 나타내었다 칼슘 섭취량이 RDA 66.7% 미만의 경우가 고등학교 여학생에서 54.9%로 다른 집단보다 높게 나타났으며 특히 여고생들이 운동의 횟수나 운동량이 적다는 사실도 함께 나타나 이 집단에 대한 영양교육의 필요성이 절실하였다. 또한 청소년들의 칼슘급원 식품군은 우유 및 유제품, 채소류, 어패류 및 곡류 순이었으며, 칼슘섭취량은 칼슘에 대한 영양지식과 양의 상관관계를 보여 인식이 높을수록 칼슘섭취량이 많은 것으로 나타났다.

• Journal of Ginseng Research
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• 제48권3호
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• pp.245-252
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• 2024

Ginseng is a traditional herbal medicine used for prevention and treatment of various diseases as a tonic. Recent scientific cohort studies on life prolongation with ginseng consumption support this record, as those who consumed ginseng for more than 5 years had reduced mortality and cognitive decline compared to those who did not. Clinical studies have also shown that acute or long-term intake of ginseng total extract improves acute working memory performance or cognitive function in healthy individuals and those with subjective memory impairment (SMI), mild cognitive impairment (MCI), or early Alzheimer's disease (AD) dementia who are taking AD medication(s). Ginseng contains various components ranging from classical ginsenosides and polysaccharides to more recently described gintonin. However, it is unclear which ginseng component(s) might be the main candidate that contribute to memory or cognitive improvements or prevent cognitive decline in older individuals. This review describes recent clinical contributors to ginseng components in clinical tests and introduces emerging evidence that ginseng components could be novel candidates for cognitive improvement in older individuals, as ginseng components improve SMI cognition and exhibits add-on effects when coadministered with early AD dementia drugs. The mechanism behind the beneficial effects of ginseng components and how it improves cognition are presented. Additionally, this review shows how ginseng components can contribute to SMI, MCI, or early AD dementia when used as a supplementary food and/or medicine, and proposes a novel combination therapy of current AD medicines with ginseng component(s).

• Journal of Applied Biological Chemistry
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• 제54권2호
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• pp.101-107
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• 2011

Aging in females is associated with a reduced metabolic function, increased incidence of neurodegenerative diseases, and cognitive dysfunction, as a result of loss in gonadal function. The change can alter the states of phosphorylation on the proteins, which cause dramatic changes in the cellular location or activity of the proteins. In this study, the differential phosphorylation of the proteins responsible for the functions related to cognition was studied using the ovariectomized adult rats. Phosphoproteomic analysis using the cerebral and hippocampal tissues could identify 51 differentially phosphorylated proteins including 12 proteins for energy metabolism, 8 cytoskeletal proteins, 6 signaling proteins, and other functional proteins in the ovariectomized rats. Further, anti-oxidative enzymes, superoxide dismutase and peroxiredoxin-2, which are known to be inactivated by phosphorylation, were found to be differentially phosphorylated in the cerebellum and hippocampus of the ovariectomized rats, respectively. Many of the deactivated proteins by differential phosphorylation identified in this study were overlapped to those of Alzheimer's disease cases. These results will provide information for neurodegenerative learning and memory impairments in women as brought about by menopause.

• Animal Bioscience
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• 제35권9호
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• pp.1454-1460
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• 2022

Objective: Early environmental enrichment in life can improve cognition in animals. The effect of prenatal auditory stimulation on learning ability and fear level in chick embryos remained unexplored. Therefore, this study investigated the effect of prenatal auditory stimulation on the learning ability and fear level of chicks. Methods: A total of 450 fertilized eggs were randomly divided into 5 groups, including control group (C), low-sound intensity music group (LM), low-sound intensity noise group (LN), high-sound intensity noise group (HN) and high-sound intensity music group (HM). From the 10th day of embryonic development until hatching, group LM and group LN received 65 to 75 dB of music and noise stimulation. Group HN and group HM received 85 to 95 dB of noise and music stimulation, and group C received no additional sound. At the end of incubation, the one-trial passive avoidance learning (PAL) task and tonic immobility (TI) tests were carried out, and the serum corticosterone (CORT) and serotonin (5-HT) concentrations were determined. Results: The results showed that compared with the group C, 65 to 75 dB of music and noise stimulation did not affect the PAL avoidance rate (p>0.05), duration of TI (p>0.05) and the concentration of CORT (p>0.05) and 5-HT (p>0.05) in chicks. However, 85 to 95 dB of music and noise stimulation could reduce duration of TI (p<0.05) and the concentration of CORT (p<0.05), but no significant effect was observed on the concentration of 5-HT (p>0.05) and PAL avoidance rate (p>0.05). Conclusion: Therefore, the prenatal auditory stimulation of 85 to 95 dB can effectively reduce the fear level of chicks while it does not affect the learning ability.

• 한국축산식품학회지
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• 제43권4호
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• pp.612-624
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• 2023

The gut-brain axis encompasses a bidirectional communication pathway between the gastrointestinal microbiota and the central nervous system. There is some evidence to suggest that probiotics may have a positive effect on cognitive function, but more research is needed before any definitive conclusions can be drawn. Inflammation-induced by lipopolysaccharide (LPS) may affect cognitive function. To confirm the effect of probiotics on oxidative stress induced by LPS, the relative expression of antioxidant factors was confirmed, and it was revealed that the administration of probiotics had a positive effect on the expression of antioxidant-related factors. After oral administration of probiotics to mice, an intentional inflammatory response was induced through LPS i.p., and the effect on cognition was confirmed by the Morris water maze test, nitric oxide (NO) assay, and interleukin (IL)-1β enzyme-linked immunosorbent assay performed. Experimental results, levels of NO and IL-1β in the blood of LPS i.p. mice were significantly decreased, and cognitive evaluation using the Morris water maze test showed significant values in the latency and target quadrant percentages in the group that received probiotics. This proves that intake of these probiotics improves cognitive impairment and memory loss through anti-inflammatory and antioxidant mechanisms.