• Archives of Plastic Surgery
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• 제38권6호
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• pp.791-797
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• 2011

Purpose: Angiosarcoma is a rare and aggressive malignant soft tissue tumor. Due to a lack of the established optimal treatment modalities, however, an extensive resection followed by an early detection has been reported to be the best treatment of choice. We analyzed the clinical course of six patients, hence attempted to contribute to making a treatment plan for patients with angiosarcoma. Methods: Six patients who have been surgically treated between 2005 and 2010 are included. Through a retrospective analysis of the medical records, we evaluated the pattern of disease detection, a past history, time span between the detection and the primary surgery, surgical treatment modalities, time span between the primary surgery and the recurrence/metastasis, the sites of metastasis and the secondary treatment modalities. Results: The mean age of patients was 70.5 years; all male; and the sites were the scalp. Four patients underwent the reconstruction using a local flap with a skin graft and two patients using a free flap. The mean period elapsed until the primary operation since the identification was 7.3 months and until a recurrence or a metastasis occurred following the primary operation was 12 months. Four patients had pulmonary metastasis. As a secondary therapy, four patients underwent the radiotherapy and one was treated with the chemotherapy. At the present, five patients died and one undergoes a monitoring of the clinical course. Conclusion: It would be mandatory to shorten the length of hospital stay and to return patients to their daily lives as the earliest as possible using relatively simpler surgical methods, thus attempting to give them opportunity to resume their previous normal life.

• Journal of Chest Surgery
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• 제36권10호
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• pp.789-793
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• 2003

원발성 폐동맥 육종은 매우 드문 질환이다 비특이적인 다양한 임상증상과 폐동맥 색전증 등으로 혼돈할 수도 있어 진단이 매우 어렵고, 지연될 수가 있다. 드물지만 원발성 육종이 호발하는 심장, 심막에서의 전이유무나 혹은 원격 전이에 대해서도 주의를 기울여야 한다. 저자들은 기관지 협착을 동반한 원발성 폐동맥 육종에 대해 수술 1예를 경험하였기에 문헌 고찰과 함께 보고하고자 한다.

• Journal of Chest Surgery
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• 제45권2호
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• pp.120-123
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• 2012

We detected two cases of right atrial angiosarcoma that had a similar appearance on imaging studies. Although the surgical findings were similar for the two patients, one had a clear resection margin, while the other had tumor cells in the resection margin on frozen biopsy. We suggest that preoperative data on magnetic resonance imaging and computed tomography in patients with angiosarcomas may not predict the exact extent of surgical resection or prognostic outcomes.

• 대한족부족관절학회지
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• 제18권3호
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• pp.129-132
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• 2014

Intravascular papillary endothelial hyperplasia (IPEH) has appeared in the literature under a variety of names, including Masson's tumor, Masson's hemangioma, and Masson's pseudoangiosarcoma. It is a benign lesion of the skin and subcutaneous tissue characterized by reactive proliferation of vascular endothelial cells with papillary formations. The clinical picture is not specific and the lesion resembles malignant angiosarcoma clinically and histopathologically. Therefore, it is often mistaken for angiosarcoma and a group of other benign and malignant vascular lesions. We report on a case of IPEH adherent to peripheral nerve treated with operative excision.

• 대한세포병리학회지
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• 제10권1호
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• pp.61-66
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• 1999

Angiosarcomas are rare tumors, seen most commonly in the skin and soft tissue of head and neck legion. But it has been described in numerous body sites including thyroid, breast, liver, spleen, bone, etc.. Their biological behaviors depend on the microscopic grade, site of origin, and multifocality. We report the unique cytological features of an angiosarcoma in pleural fluid. A 61-year-old woman presented with a 6 month history of dyspnea on exertion and chest pain. Chest computerized tomography(CT) revealed multiple subpleural small nodules in the right lung and widespread all space consolidation and pleural effusion in the left lung. CT of liver revealed multiple small low attenuated lesion. The smears obtained from pleural fluid showed hypocellularity with a hemorrhagic background. The tumor cells were highly pleomorphic oval or spindle in shape and presented singly, in loose groups, in knitted syncytial aggregates, and in acinar pattern. Their nuclei had vesicular chromatin with delineated, thick nuclear membranes and occasionally a large eosinophilic, prominent nucleolus. The cytoplasm was plump, thin or protected in spindly fashion. Almost ail tumor cells showed variable sized intracytoplasmic vacuoles and their nuclei were sometimes crescentic by a huge vacuole. Occasional binucleated tumor cells and mitotic figures were present. Cellular debris and streaky materials were identified. Needle biopsy specimen from the pleura revealed anastomosing slit-like spaces lined by pleomorphic tumor cells. The tumor cells showed a strong reactivity for CD31 and vimentin and focal weak reactivity for factor VIII-related antigen.

• Tuberculosis and Respiratory Diseases
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• 제41권4호
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• pp.413-417
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• 1994

저자들은 최근 2개월간의 각혈, 기침, 체중 감소를 주소로 입원한 19세 남자에서 종격동내 혼합 생식 세포종과 폐전이를 동반한 혈관육종이 동시에 존재한 중복암 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Radiation Oncology Journal
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• 제16권3호
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• pp.351-355
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• 1998

혈관육종은 전체 악성종양의 빈도에서 약 1$\%$를 차지하는 매우 드문 종양이다. 이 중 반 수 정도는 두경부에 발생하며 특히 장년 층의 남자에서 두피에 호발하는 경향을 보인다. 권고되는 치료방법으로는 수술적 제거와 방사선치료가 있으나 넓은 범위의 종양이 전 두피에 퍼져있을 때는 수술적 방법이 적용되기 힘들다. 여기 방사선 치료만으로 완전 관해를 보인 두피 혈관육종의 경우를 보고하며 엑스선과 전자선을 이용하여 간단하면서도 재현성 있는 방사선치료방법을 소개한다. 볼루스는 표면선량을 증가시키고 뇌조직의 정상세포에 대한 방사선량을 최소화시키기 위하여 사용할 수 있지만 두경부와 같이 굴곡이 심한 환자의 표면에 밀착시키기는 어렵다 Thermoplastic과 파라핀을 이용하여 제작한 헬멧을 혈관육종의 방사선 치료에 사용한 결과 전체 두피에 대한 열형광선량계에 의해 측정한 방사선량은 7$\%$ 이내의 고른 선량분포를 얻을 수 있었다.

• Archives of Plastic Surgery
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• 제42권2호
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• pp.261-263
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• 2015

• Journal of Chest Surgery
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• 제29권10호
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• pp.1160-1165
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• 1996

저자들은 지금까지 발생보고 예가 없는 좌쇄골하동맥 맥관육종 1례 수술을 치험하였다. 제 1늑골의 기형이 있는 19세 여자 환자로, 1년 전부터 점진적으로 심해진 동맥 흉곽 출구 증후군의 증상을 나타냈다. 쇄골 중앙부를 절제한 후 폐쇄된 쇄골하 동맥 제 3부분과 상완 동맥 분절을 절제하고 대복재 정맥을 이용하여 우회로 조성술을 시행하였다. 쇄골하 동맥의 병리 조직 소견은 벽재성형 맥관 육종이었으며 혈액 응고 인자 WII과 관련되는 항원에 대한 조직 화학적 염색 소견도 양성이었다. 수술전 일상 생활을 할 수 없을 정도 심한 증상이 수술후 거의 소실되었으며, 수술후 4개월된 현재 직장 생활을 계속하고 있다.

• 대한두개안면성형외과학회지
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• 제17권4호
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• pp.233-236
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• 2016

Scalp defect management is complicated secondary to reduced laxity in the scalp and forehead area. For reconstruction of larger defects with exposed bone and loss of the periosteal layer, free flap reconstruction is one option for single-stage surgery, although the procedure is lengthy and includes the possibility of flap loss. We successfully performed a single-stage reconstruction of a large scalp defect using a combination of artificial dermis, split-thickness skin graft, and full-thickness skin graft following wide excision of a cutaneous angiosarcoma, and present our method as one option for the treatment of large oncologic surgical defects in patients who are poor candidates for free flap surgery.