• Journal of Digital Convergence
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• v.19 no.4
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• pp.423-433
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• 2021

This study was to investigate the mediating effect of subjective happiness on the effect of andropause symptoms on suicidal Ideation in married middle-aged men. Final Participants were 199 married middle-aged men with andropause symptoms. Andropause symptoms, suicidal ideation, and subjective happiness of middle-aged men showed significant correlations. The mediating effect of subjective happiness on the relationship between andropause symptoms and suicidal ideation was verified. The findings revealed that an improving subjective happiness of men with andropause symptoms can be helpful for the prevention of suicidal ideation. Therefore, the researchers suggest that future researchers develop nursing interventions for the prevention of suicide ideation of men with andropause symptoms based on the results of the study, and evaluate its' effects.

• Research in Community and Public Health Nursing
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• v.16 no.2
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• pp.186-195
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• 2005

Purpose: This study aims to understand andropause symptoms and life satisfaction among middle-aged Korean men. Method: The subjects were selected among men in their middle age who visited one of two university hospitals or a convalescent center in Seoul. Korea. Eight items were used to measure their andropause symptoms. Life Satisfaction Index-Z was used to measure life satisfaction. Results: Major symptoms related andropause. in the order of frequency, include memory loss, muscle weakness. powerlessness and impotence. Among the subjects. 62.5% smoked and 70% drank alcohol. and life satisfaction was generally moderate in the participants. Current smokers and alcohol drinkers reported a low level of life satisfaction. Diabetic patients and subjects who had powerlessness and hot flashes of andropause symptoms experienced a low level of life satisfaction. Muscle weakness was more frequent in current smokers, and powerlessness more in alcohol drinkers. Conclusion: This study's findings indicate that and ropause is one of major health concerns among middle-aged men. It reminds us of the smoking and alcohol drinking issues among middle-aged men. These findings show the necessity to improve strategies for nursing intervention in andropause symptoms and health risk behaviors.

• Journal of the Korea Society of Computer and Information
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• v.25 no.9
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• pp.109-116
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• 2020

In this study, we tried to identify the relationship between subjective health Status and job stress and andropause symptoms of middle-aged male who work.. The data was based on a survey of male aged 40 to 59 in four cities and collected by surveying 154 people with jobs. The general characteristics of the difference in andropause symptoms were marital status and job satisfaction. 68.83 percent of the subjects experienced andropause symptoms. There was a negative correlation between subjective health status and job stress(r=-.204, p=.011). The correlated factors of andropause symptoms included subjective health status(r=-.248, p=.002) and job stress(r=.341, p=<.001). Factors influencing andropause symptoms are job stress, subjective health status. There is a need to develop and apply nursing intervention programs that can reduce job stress and improve subjective health status in order to effectively manage menopause symptoms of middle-aged male who work.

• Journal of Industrial Convergence
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• v.18 no.4
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• pp.23-31
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• 2020

This study is to identify the relationship between andropause symptoms, resilience, and retirement anxiety in the context of convergence. It is also to identify the factors that affect retirement anxiety by checking these relationships. For data collection, the study surveyed 87 middel-aged men who were residing in S City from July 20 to October 25, 2019. This study found that middle-aged men's anxiety about retirement has a significant influence on andropause syndrome and resilience. In addition, those with andropause syndrome had lower resilience and higher retirement anxiety than those without symptoms. Therefore, it is necessary to consider ways to efficiently overcome retirement anxiety in middle-aged men, reduce andropause symptoms, and enhance resilience.

• Journal of Digital Convergence
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• v.16 no.12
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• pp.467-475
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• 2018

The purpose of this study is to investigate the relationship andropause symptoms, stress, self-esteem and quality of life among middle-aged men. The data were collected from Jun to August 2017. The subjects were 40 to 60 year old males residing in Y city and 198 questionnaires were analyzed. A menopausal man's quality of life was significantly different according to final education, monthly income, exercise status, the scores of quality of life was negatively correlated with those of andropause symptoms and stress, but positively correlated with those of self-esteem. The result of adding six variables that have significantly different quality of life, factors influencing quality of life are self-esteem, stress, andropause symptoms, monthly income and analysis result, explaining 52.3% of the variance. Therefor, The results of this study through repeated research in the future, it will contribute to the development and application of a nursing arbitration program to improve the quality of life for men in menopause.

• The Journal of Korean Society for School & Community Health Education
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• v.24 no.3
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• pp.13-22
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• 2023

Objectives: The purpose of this study was to provide baseline data for management policies by exploring the association between alcohol and mental health in menopause and andropause middle-aged Methods: This study used the data from from the 8th National Health and Nutrition Examination Survey (2019-2021). Adults between the ages of 40 and 64 were considered menopause and andropause middle-aged and 7,704 of the total number of 8,549 subjects were selected as the final study subjects without missing data. Mental health was defined as depression diagnosis and suicidal thoughts, and drinking was defined as current drinking and high-risk drinking. SAS 9.4 was used for all statistical analyses. Results: There were significant differences between menopause middle-aged men and women in current drinking (83.4% for men and 66.6% for women) and in high-risk drinking (24.2% for men and 4.9% for women). The significant factors affecting the depression diagnosis were identified as economic activity, income level, and subjective health status for men and economic activity, income level, subjective health status, and smoking for women (p < .05). The significant factors affecting suicidal ideation included economic activity, income level, and subjective health status for men and economic activity, high-risk drinking, current smoking, and subjective health status for women (p < .05). Conclusion: As a result of analyzing the association between alcohol and mental health in menopause and andropause middle-aged adults, Drinking alcohol and high-risk drinking in women were associated with mental health, but insignificantly in men. Based on this study, it is necessary to program development and health education for the physical and mental health of menopausal middle-aged women exposed to alcohol, and to develop menopausal mental health management policies that take into account the gender differences.

• Nutrition Research and Practice
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• v.6 no.6
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• pp.505-512
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• 2012

Many aging male suffer various andropause symptoms including loss of physical and mental activities. This study evaluated the putative alleviative effects of CRS-10 dandelion and rooibos extract complex (CRS-10) on the symptoms of andropause. The survival rate of TM3 Leydig cells (TM3 cells) treated with CRS-10 was measured based on typical physiological stress. After daily intake of CRS-10 for 4 weeks, the level of testosterone, physical activity and both the number and activity of sperm in older rats (18 weeks) were measured. Furthermore, thirty males were surveyed with AMS (Aging Males' Symptoms) questionnaire after intake of 400 mg of CRS-10. Overall, CRS-10 protected TM3 cells from serum restriction and oxidative stress via activation of ERK and Akt pathways. The level of testosterone and activation of spermatogenesis in rats were significantly enhanced. In addition, physical locomotion was markedly improved. Daily intake of 400 mg of CRS-10 improved the quality of life among agingmale respondents, according to a clinical survey using the AMS. The results indicate the potential of CRS-10 as a safe and efficacious natural substance for reducing or alleviating andropause symptoms.

• Journal of Life Science
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• v.26 no.9
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• pp.1063-1073
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• 2016

Male climacteric syndrome, andropause, or testosterone deficiency syndrome (TDS) is one of the new health issues in elderly men. It is a natural phenomenon that happens with age in men, which is clinically characterized by a decline in levels of serum testosterone resulting in a significantly decreasing of physical and mental activities. The aim of this study was to investigate the putative alleviative effects of dandelion extract on the symptoms of TDS by increasing serum testosterone levels and compare the efficacy between dandelion extract (DE) and fermented dandelion extract (FDE). After daily intake of DE and FDE for 4 weeks, serum testosterone levels, muscles of vastus lateralis, forced swimming time, total sperm counts, and motile sperm counts were significantly increased in older rats (22 weeks). Additionally, SHBG, epididymal fat pad, total serum cholesterol and triglyceride were significantly decreased in DE and FDE fed groups. However, PSA levels were not different among all groups. Furthermore, DE and FDE enhanced the expression of genes related to testosterone biosynthesis in TM3 Leydig cells. Overall, these positive effects on andropause were greater in FDE compared to DE. These results suggest the potential of FDE as a safe and efficacious natural material for recovering testosterone levels and reducing andropause symptoms.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.11
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• pp.1571-1579
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• 2016

We investigated the effect of peanut sprout extract (PSE) on andropause symptoms. PSE was evaluated for impotency and benign prostatic hyperplasia via phosphodiesterase (PDE) or 5-alpha reductase II inhibition assay. Inhibition of PDE and 5-alpha reductase II activities in PSE was significantly higher than that of the non-treated control. To investigate the effects of testosterone levels by PSE, we performed cell media test using TM3 cells. Production of testosterone in TM3 cells was elevated by PSE. These results indicate that PSE was able to alleviate andropause symptoms.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.5
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• pp.403-408
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• 2015

Traditionally, 5 kinds of fruits with "ja(子)" in their name, including Rubus coreanus, Schisandra chinensis, Lycinum chineuse, Torilidis fructus, and Cuscuta seed, collectively called Oja(五子), are long known to enhance stamina. In the present study, we replaced tosaja with gyeolmyeongja(Cassiae semen ) and examined the effects of extracts from these fruits on andropause. This study investigated the antioxidant effect and testosterone synthesis of Oja water extract on Leydig TM3 cells. To investigate whether hydrogen peroxide induces oxidative stress in Leydig cells, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay, nitric oxide assay, and testosterone assay were performed on mouse Leydig TM3 cells. The results were obtained as follows: Leydig TM3 cells viability was assessed by a modified MTT assay, and the protection effect of Oja water extract against hydrogen peroxide-induced cell oxidative stress were examined by mitochondrial activity. Oja water extract could efficiently protect cytotoxicity induced by H₂O₂. Oja water extract promoted testosterone synthesis. These results suggest that Oja water extract has protective roles and promotes steroidogenesis in Leydig cells through its anti-oxidant action.