• Corrosion Science and Technology
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• v.8 no.6
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• pp.238-242
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• 2009

Corrosion of metallic materials occurs by the reaction with corrosive environment. In general, corrosive environments are classified as atmospheric, marine, soil etc. and regardless of any corrosive environments, reduction of thickness and cracking and degradation are induced by corrosion. Among several corrosive environments, knowing the atmospheric corrosiveness of a region, city, or country is considered of ultimate importance for major industrialists and investors who require knowledge of the corrosive impact of the atmosphere on everyday materials such as carbon steel, weathering steel, zinc, copper, and aluminium. This is why the atmospheric corrosiveness map is needed. This paper dealt with corrosion properties between several waters in the region and carbon steel, weathering steel, galvanized steel, pure copper, and pure aluminium at the representative rural area of Korea - Andong.

• The Korean Journal of Mycology
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• v.37 no.2
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• pp.139-143
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• 2009

Several entomopathogenic fungi have been exploited to be developed into biological control agents in insect pest management. The beet armyworm, Spodoptera exigua, is a serious insect pest infesting various crops, but not effectively controlled by commercial chemical pesticides due to its high insecticide resistance. A fungal isolate was isolated from S. exigua larvae collected from cabbage field in Andong, Korea. The fungus could be cultured in potato dextrose agar. Larvae of S. exigua injected with the cultured conidia showed a potent entomopathogenicity. To identify the fungus isolate, its internal transcribed space (ITS) and surrounding partial 18S/28S regions were sequenced. The ITS sequence was highly matched (99%) to that of Nomuraea rileyi. Morphological characters of its hyphae and conidia were well fit to those of known N. rileyi. This study reports the first record of an entomopathogenic fungus, N. rileyi, in Korea.

• Korean Journal of Plant Resources
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• v.22 no.6
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• pp.498-505
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• 2009

The plant Agastache rugosa Kuntze has various physiological and pharmacological activities. Especially, it has been regarded as a valuable source for the treatment of anti-inflammatory and oxidative stress-induced disorders. However, little has been known about the functional role of it on oxidative damage in mammalian cells by ROS. In this study, we investigated the DPPH radical, hydroxyl radical, hydrogen peroxide and intracellular ROS scavenging capacity, and $Fe^{2+}$ chelating activity of the extracts from Agastache rugosa. In addition, we evaluated whether the extract can be capable of reducing $H_2O_2$-induced DNA and cell damage in NIH 3T3 cells. These extracts showed a dose-dependent free radical scavenging capacity and a protective effect on DNA damage and the lipid peroxidation causing the cell damage by $H_2O_2$. Therefore, these results suggest that Agastache rugosa is useful as a herbal medicine for the chemoprevention against oxidative carcinogenesis.

• Proceedings of the Korea Information Processing Society Conference
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• 2015.10a
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• pp.977-979
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• 2015

최근, 에디터 형태의 게임엔진들이 제공되어 게임 제작의 높은 진입장벽이 낮아지고 있다. 본 논문은 에디터 형태의 게임엔진 중 하나인 Unity 3D를 활용하여 일반 사용자의 관점에서 혼자 게임을 제작하기 위한 방법으로 이벤트기반 모듈 기획 방법을 제안하고자 한다. 이는 1인 게임 제작의 관점을 기획에 맞추어 게임의 전체적인 진행과정에서 동작하는 행동과 역할들을 모듈 단위로 기획하는 방법이다. 그리고 각 모듈은 게임성을 표현하는 다양한 이벤트들을 포함한다. 또한 Unity 3D에서 제공하는 스크립트 기능은 제안하는 모듈 구조를 구현하기에 적합하여 Unity 3D를 활용한다. 마지막으로 제안하는 방법을 통해 기획에서 개발까지 효과적인 게임 제작이 가능한지 여부를 확인하기 위해 간단한 모바일 캐주얼 게임을 제작하였다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.05a
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• pp.819-821
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• 2014

This study is proposed the design method of tag to measure biomedical signal for interfacing with smart phone. The measurable physiological signals are ECG and PPG. On the smart phone by using the measured signals, we have designed the tag that can extract parameters such as heart rate, heart rate distribution, mean blood pressure, arterial stiffness, autonomic nervous balance. By using the estimated medical informations from this tag, One's health status will be able to manage one.

• Proceedings of the Korea Information Processing Society Conference
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• 2013.11a
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• pp.538-541
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• 2013

택시는 많은 사람들이 이용하고 있는 교통수단이다. 특히 버스나 지하철 같은 대중교통 운행시간이 끝나는 야간에는 택시의 이용률이 더 많을 수밖에 없다. 그러나 최근 택시를 이용한 범죄가 많이 발생하면서 택시에 대한 사람들의 불안감이 커져가고 있다. 본 논문에서는 스마트폰을 이용하여 택시를 보다 안전하게 이용할 수 있는 시스템과 앱을 설계하였다. 스마트폰의 NFC 기술을 이용하여 인증된 택시에 부착된 NFC 태그를 인식하게 되면 택시정보와 탑승정보를 미리 등록된 지인들에게 실시간으로 전송하게 된다. 그로 인해 탑승자들은 보다 더 안전하게 택시를 이용하게 될 것을 기대할 수 있다.

• Korean Journal of Plant Resources
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• v.35 no.6
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• pp.697-703
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• 2022

Under the COVID-19 pandemic, interest in immune enhancement is increasing. Although the immune-enhancing activity of plants of the genus Hibiscus has been reported, there is no study on the immune-enhancing activity of H. syriacus. Thus, in this study, we investigated the immune-enhancing activity of Hibiscus syriacus leaves (HSL) in mouse macrophages, RAW264.7 cells, and immunosuppressed mice. HSL increased the production of immunostimulatory factors such as nitric oxide (NO), inducible nitric oxide synthase (iNOS), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) and activated the phagocytosis in RAW264.7 cells. The HSL-mediated production of immunostimulatory factors was dependent on toll-like receptor 4 (TLR4), p38, and c-Jun N-terminal kinase (JNK) in RAW264.7 cells. In the immunosuppressed mouse model, HSL increased the spleen index, the levels of the cytokines, and the numbers of lymphocytes, neutrophils, and monocytes. Taken together, HSL may be considered to have immune-enhancing activity and be expected to be used as a potential immune-enhancing agent.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2022.09a
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• pp.92-92
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• 2022

Under the COVID-19 pandemic, interest in immune enhancement is increasing. Although the immune-enhancing activity of plants of the genus Hibiscus has been reported, there is no study on the immune-enhancing activity of H. syriacus. Thus, in this study, we investigated the immune-enhancing activity of Hibiscus syriacus leaves (HSL) in mouse macrophages, RAW264.7 cells, and immunosuppressed mice. HSL increased the production of immunostimulatory factors such as nitric oxide (NO), inducible nitric oxide synthase (iNOS), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) and activated the phagocytosis in RAW264.7 cells. The HSL-mediated production of immunostimulatory factors was dependent on toll-like receptor 4 (TLR4), p38, and c-Jun N-terminal kinase (JNK) in RAW264.7 cells. In the immunosuppressed mouse model, HSL increased the spleen index, the levels of the cytokines, and the numbers of lymphocytes, neutrophils, and monocytes. Taken together, HSL may be considered to have immune-enhancing activity and be expected to be used as a potential immune-enhancing agent.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2023.04a
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• pp.44-44
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• 2023

Syneilesis palmata (SP) has been used as a traditional medicinal plant and vegetable. SP was reported to exert pharmacological activities such as anti-inflammation, anti-cancer, and anti-HIV. However, there are no studies on the immunostimulatory activity of SP. Thus, in this study, we report that S. palmata leaves (SPL) induce the activation of macrophages. An increase in both secretions of immunostimulatory mediators and phagocytotic activity was observed in SPL-treated RAW264.7 cells. However, this was reversed by inhibition of TLR2/4. In addition, the p38 inhibition reduced the SPL-mediated secretion of immunostimulatory mediators, and the SPL-mediated p38 activation was blocked by the TLR2/4 inhibition. SPL augmented both p62/SQSTM1 and LC3-II. TLR2/4 inhibition blocked the SPL-mediated increase of p62/SQSTM1 and LC3-II. These findings indicate that SPL may activate macrophages through TLR2/4-dependent p38 activation and activate autophagy through TLR2/4 stimulation.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2023.04a
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• pp.47-47
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• 2023

Paeonia lactiflora roots (PLR) are a medicinal plant widely used for treating inflammatory diseases. However, PLR has been recently reported to increase the production of proinflammatory mediators and activates phagocytosis in macrophages. Thus, in this study, we tried to verify the macrophage activation of PLR and elucidate its mechanism of action. PLR upregulated the production of proinflammatory mediators and activated phagocytosis in RAW264.7 cells. However, these effects were reversed by inhibition of TLR2/4. In addition, the inhibition of p38, JNK, and ERK1/2 reduced the PLR-mediated production of proinflammatory mediators, and the PLR-mediated activation of p38, JNK, and ERK1/2 was blocked by the TLR4 inhibition. These findings indicate that PLR may activate macrophages through TLR4-dependent activation of p38, JNK, and ERK1/2. These indicate that PLR has immunostimulatory activity. Thus, it is believed that PLR can be used as a functional food agent that enhances the immune system.