• Journal of Korean Physical Therapy Science
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• v.24 no.1
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• pp.1-13
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• 2017

Purpose: The objective of this study was compare the effect of core muscle strengthening between core exercise on stable surface and core exercise on unstable surface. Methods: Thirty-nine adults participated in this study and were randomly allocated to three groups. The stable surface exercise group and unstable surface exercise groups practiced core muscle training for $3{\times}30minute$ sessions over a 4-week period. The control group did not received therapeutic intervention except pre and post test. The following clinical tools were used to assess core muscle strength and balance: Side Plank Test, Trunk Flexion Test, Balance Error Scoring Test, Core Muscle Stength & Stability Test. Results: The stable surface exercise group showed significant improvement in trunk muscle strength of anterolateral part as revealed by the Side Plank Test and Trunk flexion Test(p<.05). The unstable surface exercise group showed significant improvement in trunk muscle strength of anterolateral part and balance ability as revealed by the Balance Error Scoring Test and Core Muscle Strength & Stability Test(p<.05). Conclusion: The results of this study, both core exercise on stable surface and core exercise on unstable surface induced core muscle strengthening and balance ability. Expecially core exercise on unstable surface more effective to core muscle strengthening and balance ability.

• Korean Journal of Pharmacognosy
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• v.36 no.4 s.143
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• pp.263-272
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• 2005

To develop safe and new anticoagulation agents from natural resources, the inhibitory activities of 291 methanol extracts, which were prepared from different parts of 197 medicinal and wild plants, against human thrombin were evaluated. Based in anti-coagulation activity determined by thrombin time and activated partial thromboplastin time, the extract of leaf of Myrica rubra was finally selected. The extract of M. rubra showed a strong thrombin inhibitory activity (above 1,819%) at 0.5 mg/ml as a final concentration, whereas aspirin showed 337% inhibition at concentration of 1.5 mg/ml. The activity of the extract remained more than 85% and 60% by heat treatment at $100^{\circ}C$ for 30min, and acid treatment at pH 2 for 60 min, respectively. Our results suggested that the extract of Myrica rubra could be the potential source as thrombin inhibitor.

• Korean Journal of Plant Resources
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• v.28 no.3
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• pp.297-304
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• 2015

The flower buds of Sophora japonica L (SF), as a well-known traditional Chinese medicinal herb, have been used to treat bleeding-related disorders such as hematochezia, hemorrhoidal bleeding, dysfunctional uterine bleeding, and diarrhea. However, no specific anti-cancer effect and its molecular mechanism of SF have been described. Thus, we performed in vitro study to investigate if treatment of SF affects activating transcription factor 3 (ATF3) expression and ATF3-mediated apoptosis in human colorectal cancer cells. The effects of SF on cell viability and apoptosis were measured by MTT assay and Western blot analysis against cleaved poly (ADP-ribose) polymerase (PARP). ATF3 activation induced by SF was evaluated using Western blot analysis, RT-PCR and ATF3 promoter assay. SF treatment caused decrease of cell viability and increase of apoptosis in a dose-dependent manner in HCT116 and SW480 cells. Exposure of SF activated the levels of ATF3 protein and mRNA via transcriptional regulation in HCT116 and SW480 cells. Inhibition of extracellular signal-regulated kinases (ERK) 1/2 by PD98059 and p38 by SB203580 attenuated SF-induced ATF3 expression and transcriptional activation. Ectopic ATF3 overexpression accelerated SF-induced cleavage of PARP. These findings suggest that SF-mediated apoptosis may be the result of ATF3 expression through ERK1/2 and p38-mediated transcriptional activation.

• Korean Journal of Mineralogy and Petrology
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• v.33 no.4
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• pp.377-389
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• 2020

In this study, pollution characteristics were investigated for the Andong Dam sediments in the Nakdong River. Sediment samples were collected from the middle, left, and right points of the lake up to 40km upstream of the Andong Dam at intervals of about 5km by stratification and turnover period. In the case of nutrients and total organics such as loss of ignition, total nitrogen, and phosphorus, the degree of contamination is low, but heavy metals of arsenic and cadmium is very high. The contamination level of sediments in the dam area is higher than that of the branch of river and the control group, and concentration of chromium, copper, and lead are higher in the stratification period, and that of zinc is higher in turnover period. Arsenic, cadmium, manganese, and zinc showed contamination variation between upstream and downstream but chromium, copper, mercury, iron and lead didn't show the variation.

• Proceedings of the Korean Magnestics Society Conference
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• 2003.12a
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• pp.267-267
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• 2003

• Proceedings of the Korean Nutrition Society Conference
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• 2001.11a
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• pp.74-74
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• 2001

• Proceedings of the Korean Nutrition Society Conference
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• 2003.05a
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• pp.132.2-132.2
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• 2003

• Proceedings of the Korea Multimedia Society Conference
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• 2012.05a
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• pp.322-322
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• 2012

• Proceedings of the Korean Nutrition Society Conference
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• 2004.05a
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• pp.110-110
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• 2004

• Proceedings of the Korean Society of Applied Entomolohy Conference
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• 2002.05a
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• pp.186-186
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• 2002