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Potential influence of κ-casein and β-lactoglobulin genes in genetic association studies of milk quality traits

  • Zepeda-Batista, Jose Luis;Saavedra-Jimenez, Luis Antonio;Ruiz-Flores, Agustin;Nunez-Dominguez, Rafael;Ramirez-Valverde, Rodolfo
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.12
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    • pp.1684-1688
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    • 2017
  • Objective: From a review of published information on genetic association studies, a meta-analysis was conducted to determine the influence of the genes ${\kappa}-casein$ (CSN3) and ${\beta}-lactoglobulin$ (LGB) on milk yield traits in Holstein, Jersey, Brown Swiss, and Fleckvieh. Methods: The GLIMMIX procedure was used to analyze milk production and percentage of protein and fat in milk. Models included the main effects and all their possible two-way interactions; not estimable effects and non-significant (p>0.05) two-way interactions were dropped from the models. The three traits analyzed used Poisson distribution and a log link function and were determined with the Interactive Data Analysis of SAS software. Least square means and multiple mean comparisons were obtained and performed for significant main effects and their interactions (p<0.0255). Results: Interaction of breed by gene showed that Holstein and Fleckvieh were the breeds on which CSN3 ($6.01%{\pm}0.19%$ and $5.98%{\pm}0.22%$), and LGB ($6.02%{\pm}0.19%$ and $5.70%{\pm}0.22%$) have the greatest influence. Interaction of breed by genotype nested in the analyzed gene indicated that Holstein and Jersey showed greater influence of the CSN3 AA genotype, $6.04%{\pm}0.22%$ and $5.59%{\pm}0.31%$ than the other genotypes, while LGB AA genotype had the largest influence on the traits analyzed, $6.05%{\pm}0.20%$ and $5.60%{\pm}0.19%$, respectively. Furthermore, interaction of type of statistical model by genotype nested in the analyzed gene indicated that CSN3 and LGB genes had similar behavior, maintaining a difference of more than 7% across analyzed genotypes. These results could indicate that both Holstein and Jersey have had lower substitution allele effect in selection programs that include CSN3 and LGB genes than Brown Swiss and Fleckvieh. Conclusion: Breed determined which genotypes had the greatest association with analyzed traits. The mixed model based in Bayesian or Ridge Regression was the best alternative to analyze CSN3 and LGB gene effects on milk yield and protein and fat percentages.

Extension Method of Association Rules Using Social Network Analysis (사회연결망 분석을 활용한 연관규칙 확장기법)

  • Lee, Dongwon
    • Journal of Intelligence and Information Systems
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    • v.23 no.4
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    • pp.111-126
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    • 2017
  • Recommender systems based on association rule mining significantly contribute to seller's sales by reducing consumers' time to search for products that they want. Recommendations based on the frequency of transactions such as orders can effectively screen out the products that are statistically marketable among multiple products. A product with a high possibility of sales, however, can be omitted from the recommendation if it records insufficient number of transactions at the beginning of the sale. Products missing from the associated recommendations may lose the chance of exposure to consumers, which leads to a decline in the number of transactions. In turn, diminished transactions may create a vicious circle of lost opportunity to be recommended. Thus, initial sales are likely to remain stagnant for a certain period of time. Products that are susceptible to fashion or seasonality, such as clothing, may be greatly affected. This study was aimed at expanding association rules to include into the list of recommendations those products whose initial trading frequency of transactions is low despite the possibility of high sales. The particular purpose is to predict the strength of the direct connection of two unconnected items through the properties of the paths located between them. An association between two items revealed in transactions can be interpreted as the interaction between them, which can be expressed as a link in a social network whose nodes are items. The first step calculates the centralities of the nodes in the middle of the paths that indirectly connect the two nodes without direct connection. The next step identifies the number of the paths and the shortest among them. These extracts are used as independent variables in the regression analysis to predict future connection strength between the nodes. The strength of the connection between the two nodes of the model, which is defined by the number of nodes between the two nodes, is measured after a certain period of time. The regression analysis results confirm that the number of paths between the two products, the distance of the shortest path, and the number of neighboring items connected to the products are significantly related to their potential strength. This study used actual order transaction data collected for three months from February to April in 2016 from an online commerce company. To reduce the complexity of analytics as the scale of the network grows, the analysis was performed only on miscellaneous goods. Two consecutively purchased items were chosen from each customer's transactions to obtain a pair of antecedent and consequent, which secures a link needed for constituting a social network. The direction of the link was determined in the order in which the goods were purchased. Except for the last ten days of the data collection period, the social network of associated items was built for the extraction of independent variables. The model predicts the number of links to be connected in the next ten days from the explanatory variables. Of the 5,711 previously unconnected links, 611 were newly connected for the last ten days. Through experiments, the proposed model demonstrated excellent predictions. Of the 571 links that the proposed model predicts, 269 were confirmed to have been connected. This is 4.4 times more than the average of 61, which can be found without any prediction model. This study is expected to be useful regarding industries whose new products launch quickly with short life cycles, since their exposure time is critical. Also, it can be used to detect diseases that are rarely found in the early stages of medical treatment because of the low incidence of outbreaks. Since the complexity of the social networking analysis is sensitive to the number of nodes and links that make up the network, this study was conducted in a particular category of miscellaneous goods. Future research should consider that this condition may limit the opportunity to detect unexpected associations between products belonging to different categories of classification.

Factors Associated with the Beautician's Dyspepsia (미용사의 소화장애 관련요인)

  • Kim, Eun-Suk;Kim, Young-Chul
    • Korean Journal of Health Education and Promotion
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    • v.23 no.3
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    • pp.121-134
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    • 2006
  • Objectives: This study was conducted to analyze the general properties of beauticians and to analyze correlation between their experiences of indigestion and relevant factors and thus to provide basic data to prevent obstacles to beautician's health. Methods: A self-administered survey on 257 female beauticians in Daegu from March 15 to May 30, 2005 was conducted. Cross-link analysis was used to examine indigestion in relation to the general properties of beauticians, and correlation analysis was used to determine the level of relationship between indigestion and relevant factors, and multiple regression analysis was used to determine the degree of effects of relevant factors on indigestion. Results: The results can be summarized as follows: 1. As for indigestion by general properties and beauty-related properties, there were significant differences in gender(p<0.01), age(p<0.05) and marriage status(p<0.05) among general properties and there were significant differences in the number of holiday(p<0.05), beauty culture career(p<0.01), and the degree of satisfaction on duty(p<0.001) among beauty-related properties. As for indigestion by eating habit and health-related properties, there were significant differences in the degrees of regular eating(p<0.001) and regular living habit(p<0.001), and eating speed(p<0.01). 2. Factors relevant to the eating habit showing significant correlation with indigestion were regular eating habit, taking well-balanced nutrition, and taking salty food. Among them, the regular eating habit was shown to be the most relevant with the correlation coefficient of -0.253(p<0.01). The general and beauty-related factors showing significant correlation with indigestion were beauty culture career, number of holiday, and regular living habit. And regular living habit was shown to be the most relevant with the correlation coefficient of -0.260(p<0.001). 3. Results from the regression analysis showed that relevant factors having significant effects on indigestion were gender, beauty culture career, satisfaction on duty, eating speed, regular eating habit and regular living habit. And satisfaction on duty was found to have the greatest effect on indigestion. Conclusions: The findings of this study could be effectively used to develop a practical management strategy to prevent $beauticia{\acute{n}}s$ indigestion, and to promote $beauticia{\acute{n}}s$ health, and ultimately to improve the $beauticia{\acute{n}}s$ quality of life.

The Double Mediating Effect of Job Stress and Psychological Commitment between Organizational Incivility and Job Satisfaction of Child Care Teachers in Korea (보육교사의 조직 무례와 직무만족의 관계에서 직무스트레스와 심리적 몰입의 이중매개효과 )

  • Siline Ahmad;Chang Seek Lee
    • Industry Promotion Research
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    • v.8 no.3
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    • pp.51-60
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    • 2023
  • The purpose of this study was to verify the double mediating effects of job stress and psychological commitment in the relationship between organizational incivility and job satisfaction of child-care teachers in South Korea. 234 Korean child-care teachers were purposively selected from S city of C Province. SPSS Win.25.0 and PROCESS Macro 4.2 were used for analyzing the data, and reliability analysis, frequency analysis, correlation analysis, and multiple mediation model analysis were conducted. Results are as follows. First, correlation analysis showed significant correlations between organizational incivility, job stress, psychological commitment, and job satisfaction. Second, path analysis showed that organizational incivility had a positive effect on job stress and a negative effect on psychological commitment and job satisfaction. Job stress had a negative and significant effect on psychological commitment and job satisfaction, and psychological commitment had a positive and significant effect on job satisfaction. Third, job stress and psychological commitment had consecutive double mediation in the link between organizational incivility and job satisfaction. This study suggests a way to utilize job stress and psychological commitment when childcare teachers' organizational incivility has a negative effect on job satisfaction.

Operation of Community Resident Groups in a Community-Based Participatory Health Promotion Program for Low-income Older Adults (저소득층 노인의 건강증진을 위한 지역사회 참여형 연구에서 지역사회 주민 조직의 구성과 운영)

  • Yoo, Seung-Hyun;Butler, James;Elias, Thistle I.
    • Korean Journal of Health Education and Promotion
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    • v.26 no.5
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    • pp.15-26
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    • 2009
  • Objectives: This paper is intended to illustrate and to discuss the organization and functioning of community resident groups (CRGs) in a community-based participatory health promotion program for healthy aging. Methods: CRGs were convened in 12 government-subsidized apartment communities for low-income seniors in Pennsylvania, U.S.A., to promote healthy aging. Researchers facilitated CRG meetings following a 6-step process of community empowerment and utilizing a social ecological model for assessment and planning. Almost 200 project-related documents were qualitatively analyzed using matrix analysis principles such as cross-classification of multiple dimensions to identify patterns in the data and matrix building for displaying such patterns. Results: CRGs were venues at which apartment building residents could interact, discuss health priorities, and become change agents in their building. CRG members' community health priorities were about their daily living, including building conditions, poor access to fresh food, and unhealthy resident relations. Specific patterns arose in analysis indicating that leadership withing the CRGs, consistency of meetings and participants' attendance, and ability to link health concerns to daily experience impacted the CRGs' capability to identify and accomplish their goals. Conclusion: Community health issues and solutions to those issues identified by CRGs were unique to community contexts and interests. Consistent participation by community members, a consistent pattern of group activities such as monthly meetings, and having established leadership to manage CRG activities were prominent characteristics of community group functioning.

Mediating Effects of Perceived Risk and Usefulness between Online Information Credibility and Intention to Use (온라인 정보의 신뢰성 및 정보 활용의도 사이의 지각된 위험과 유용성의 매개효과에 관한 연구)

  • Sun, Jonghak;Yoon, Jung-Hyeon
    • Management & Information Systems Review
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    • v.33 no.4
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    • pp.99-118
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    • 2014
  • Using the theory of attribution, this study investigates the determinants if controllability and explores underlying dimensions of online information credibility, and then investigates if the credibility of online information influences the users' intention to use the online information for evaluating or judging the involved products. Moreover, as a research attempt to investigate the impacts of online information credibility, this study examines whether the main effect of perceived online information credibility on the intention of using online information to make a decision of purchase is mediated by both perceived risk and perceived usefulness. A total of 287 survey forms were collected from online consumers. We examined reliability by exploring internal consistency of the multiple item scales in the overall sample. Convergent and discriminant validity were also examined for evidence of construct validity. Then, PLS technique was employed to test the research model. As a result of analyzing data from a dataset of 287 responses via PLS technique, it is found that (1) both sources (controllability and stability) of perceived credibility are significantly associated with both perceived risk and perceived usefulness, and (2) perceived risk as well as perceived usefulness partially mediate the link between the two sources of credibility and intention to use. The findings of this study also suggest that the two dimensions of online information credibility influence information recipient's intention to use. Moreover, the online information including descriptions about controllability and stability can trigger potential consumers to perceive risk about consumption of the informed products and services. Therefore, providing online information with highly described controllability and stability can increase not only the credibility of the online information itself, but also the intention to use the online information through perceived risk and usefulness.

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Design and Implementation of a Subscriber Interface Management System in ATM Network (ATM망을 위한 가입자 인터페이스 관리 시스템의 설계 및 구현)

  • Lee, Byeong-Gi;Jo, Guk-Hyeon
    • Journal of KIISE:Computing Practices and Letters
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    • v.5 no.6
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    • pp.782-792
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    • 1999
  • 효과적인 ATM 망의 관리는 연결 지향 환경, 다양한 서비스 등급, 대규모 트래픽, 가상 망 구성 그리고 여러가지 트래픽 유형 등과 같은 다양한 ATM 특성을 다룰 수 있어야만 한다. 이를 위해 ATM 포럼에서는 ATM 장치, 사설망, 공중망 및 그들간의 상호작용을 지원하기 위한 ATM 망 관리 참조 모델을 정의하였으며, 그 중 하나가 서로 다른 판매자로부터의 ATM 장비들간의 상호동작성을 보장하기 위해 SNMP 기반 망 관리 프로토콜을 통해 상호 연결된 인터페이스를 관리할 수 있도록 정의된 통합 지역 관리 인터페이스(ILMI) 프로토콜이다. ILMI의 목적은 두 인접한 ATM 장치로 하여금 그들 간에 공통의 ATM 링크에 대한 동작 파라메타를 자동적으로 구성할 수 있도록 함으로서, 관리자에 의해 수동 구성이 아닌 ATM 장치 상호간의 플러그 앤 플러그 기능을 지원하는데 있다. 본 논문에서는 이러한 ILMI 기술을 바탕으로 공중망 ATM 교환기에 연결된 가입자의 물리 인터페이스, ATM 계층 인터페이스, VPC 및 VCC의 구성 및 상태 정보를 효율적으로 관리하며, 가입자 시스템의 ATM 주소를 자동으로 등록, 관리할 수 있도록 하는 가입자 인터페이스 관리 시스템(SIMS)을 설계하고, 구현하였다. Abstract An effective ATM management must address the various features of ATM such as connection-oriented environment, varying class of service, large scale traffic, virtual network configurations and, and multiple traffic types. For this, ATM network management reference model defined by ATM Forum describes the various types of network management needed to support ATM devices, private networks, public networks, and the interaction between them. One of these types is Integrated Local Management Interface (ILMI) defined to manage interconnected interface through SNMP-based network management protocol for ensuring the interoperability of ATM devices from different vendors. The purpose of ILMI is to enable two adjacent ATM devices to automatically configure the operation parameters of the common ATM link between them and then to provide a Plug and Plug function to any ATM devices with not a passive configuration by manager but a automatic configuration. This paper design and implement a Subscriber Interface Management System (SIMS) which provide automatic registration and management of ATM address of subscriber system and efficiently manages physical interface of subscriber who is connected to public ATM switch, ATM layer interface, configuration information and status information of VPC and VCC.

Promotion Strategies for Daegu-Kyungbuk Mobile Cluster: Searching for Alternative Regional Innovation Governance (대구.경북 모바일 클러스터 육성전략: 지역혁신 거버넌스의 대안 모색)

  • Lee, Jeong-Hyop;Kim, Hyung-Joo
    • Journal of the Economic Geographical Society of Korea
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    • v.12 no.4
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    • pp.477-493
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    • 2009
  • This research aims to examine Korean regional innovation governance, find structural problems, and explore alternative strategies of regional innovation governance. Especially the alternative governance was searched through the case study of Daegu-Kyungbuk mobile cluster, of which formulation Samsung is the anchor institution. Regional innovation governance in this research is defined as a policy system to link knowledge generation & diffusion subsystem and knowledge application & exploitation subsystem, and institutional conditions to steer the system. "Social Capital Assessment Tool (SOCAT)" of the World Bank was utilized for the appreciation of cluster governance. The regional innovation governance of Daegu-Kyungbuk mobile cluster is characterized as production networks dominated by one-to-one relationship between Samsung and hardware/software developers, decentralized R&D networks and policy networks with multiple hubs. Major policy agents have not developed networks with local companies, and rare are interactions between the policy agents. Local companies, especially software developers, responded they have had experiences to cooperate for local problem solving and shared their community goal, however, the degree of trust in major local project leaders is not high. Local hardware/software developers with core technologies need to be cooperative to develop similar technologies or products in Daegu-Kyungbuk mobile cluster. Regional administrative actors, such as the City of Daegu and Kyungsangbuk-do, and diverse innovation-related institutes should build cooperative environment where diverse project-based cooperation units are incessantly created, taken apart, and recreated.

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A Study on the standardization of ETCS (Focused on RF) (자동요금징수시스템(ETCS) 표준화 연구(주파수방식을 중심으로))

  • Kwon, Han-Joon;Lee, Ki-Hyun;Kim, Yong-Deak
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.7 no.3
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    • pp.62-73
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    • 2008
  • In this paper, domestic standard revision plan of dynamic frequency method which is used both in unmanned automatic toll collection system and manned collection system of the express highway is presented. For such ETCS, the infrared rays (870 nm) of active frequency method and the frequency integrated method (5.8 GHz) are adopted and extended to be operated to the all around the Toll Gate. This standardization plan is based on inter connection reference model between OSI (Open System Interconnection) in process of ITS short range radio communication standardization of 5.8 GHz bandwidth to support traffic information and control system service, and the derived revision plan by starting from physical layer which support interoperability for multiple access between RSE (Road Side Equipment) and OBE (On Board Equipment), in which is categorized into physical layer, data link layer, and application layer. In case of radiation power, existing standard is divided by class1 (within 10 m) and Class2 (within 100 m) according to transmission lengthwhile it is operated with just single standard 'Class1' because of notification of Ministry of Information and Communication in 2004. In the case of the limitation value of incident power in communication area, considering operation plan of ETCS that is on actuality operation the measurements are reflected to the standard. In other wort this paper proposed the improvement standard of incident power, pseudo response in the communication area and radiated power in order to secure stability and compatibility among operator systems about the needed part on ETCS operation.

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Cross-layer Design of Joint Routing and Scheduling for Maximizing Network Capacity of IEEE 802.11s based Multi-Channel SmartGrid NAN Networks (IEEE 802.11s 를 사용한 스마트그리드 NAN 네트워크의 최대 전송 성능을 위한 다중 채널 스케쥴링과 라우팅의 결합 설계)

  • Min, Seok Hong;Kim, Bong Gyu;Lee, Jae Yong;Kim, Byung Chul
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.5
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    • pp.25-36
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    • 2016
  • The goal of the SmartGrid is to maximize energy efficiency by exchanging bi-directional real-time power information with the help of ICT(Information and Communication Technology). In this paper, we propose a "JRS-MS" (Joint Routing and Scheduling for Multi-channel SmartGrid) algorithm that uses numerical modeling methods in IEEE 802.11s based STDMA multi-channel SmartGrid NAN networks. The proposed algorithm controls the amount of data transmission adaptively at the link layer and finds a high data-rate path which has the least interference between traffic flows in multi-channel SmartGrid NAN networks. The proposed algorithm improve transmission performance by enhancing network utilization. By comparing the results of performance analysis between the proposed algorithm and the JRS-SG algorithm in the previous paper, we showed that the JRS-MS algorithm can improve transmission performance by maximally utilizing given network resources when the number of flows are increasing in the multi-hop NAN wireless mesh networks.