• Korean Journal of Agricultural Science
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• v.23 no.2
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• pp.323-329
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• 1996

This paper is aims at studying the economics of scale of sweet potato cultivation. Sweet potato is one of the decreasing crop. Its cultivated areas has been decreasing more rapidly than soybean or corn. In this paper 23 farmers were surveyed, including 8 families with less than 1 ha, 7 families with 1-5 ha, and 8 families with more than 5 ha. The results are as follows; First, sweet potato cultivation is good for specialization, considering the high income per acre. Second, there is no good evidence explaining for the economy of scale of sweet potato cultivation, but there is an evidence for the profit of specialization. Large scale farmers have more incomes per acre, lather than more production or less management costs, by means of good sales methods. Third, mechanization of sweet potato cultivation is one of the key factor for successful large scale sweet potato cultivations.

• KSBB Journal
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• v.15 no.4
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• pp.398-401
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• 2000

Taxiods inclusive paclitaxel were produced isolated and purified from plant cell cultures of Taxus chinensis in large-scale process. their structures were elucidated by spectroscopic analyses. These compounds were exactly identical as those in previous studies from the other biomasses of Taxus chinensis and also other species. Also the concentrations of these compounds were compared with the concentration of the paclitaxel in various batches of plant cell cultures. As paclitaxel concentration increased at the end of cell cultures. the concentrations of the other paclitaxel derivatives decreased. The profile of these taxoids production can provide information for better understanding of structure-activity relationships and biosynthesis Importantly it can be utilized as an useful parameter for the quality control of paclitaxel production.

• Journal of Microbiology and Biotechnology
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• v.25 no.7
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• pp.1093-1100
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• 2015

Acetate and lactate in growth media are detrimental to the production of Thermus maltogenic amylase (ThMA), a heterologous protein, as well as to the growth of recombinant Escherichia coli. Only 50 mM of acetate or 10 mM of lactate reduced 90% of specific ThMA activity. In this study, mutant E. coli strains blocked in the ackA-pta or ackA-pta and ldh pathways were created, characterized, and assessed for their culture performace in 300 L-scale fermentation. The ackApta and ldh double-mutant strain formed significantly less lactate and acetate, and produced a concomitant increase in the excretion of pyruvate (17.8 mM) under anaerobic conditions. The ackA-pta mutant strain accumulated significant acetate but had an approximately 2-fold increase in the formation of lactate. The ackA-pta and ldh double-mutant strain had superior overall performance in large-scale culture under suboptimal conditions, giving 67% higher cell density and 66% higher ThMA activity compared with those of the control strain. The doublemutant strain also achieved a 179% improvement in volumetric ThMA production.

• Journal of Veterinary Clinics
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• v.16 no.1
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• pp.163-176
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• 1999

The nuclear transplantation technique is known as the most potential and efficient method for producing large numbers of genetically identical animals from a single embryo and somatic cells. After Dolly was introduced in 1997, many scientists were amazed. A possibility came to a reality that live offspring could be produced with differentiated somatic cells from an adult animal. On the other side, many in the press and the sensationalists focused on the socially, ethically and scientifically unacceptable sides of the technology. In this article, the history, current status and prospects of the technological development of nuclear transplantation in mammals and its application to the production of cloned animals are described. For the efficient and successful production of cloned embryos by nuclear transplantation, the right selection, preactivation and micromanipulation of oocytes as capacious recipient cytoplasm, the adequate and benefitial preparation of multiple totipotent embryonic and somatic cells as donor nuclei, fusion of them and in vitro production of cloned embryos are very critical. Recently the overall efficiency of production of cloned embryos and offspring in livestock has been much improved. Cloning will also be a more efficient, faster and useful way of creating transgenic fetuses for gene therapies, gene pharming, organs for xenotransplantation by preselection and mass production of transgenic embryos and consequently improving the production efficiency in transgenic animals. Further technical development of nuclear transplantation will enable large-scale production of cloned livestock and in near future the commercial cloning of animals will become a reality.

• Journal of the Korean Society for Precision Engineering
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• v.23 no.8 s.185
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• pp.178-184
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• 2006

Hot embossing is to fabricate desired pattern on the polymer substrate by pressing the patterned mold against the substrate which is heated above the glass transition temperature, and it is a high throughput fabrication method for bio chip, optical microstructure, etc. due to the simultaneous large area patterning. However, the bad pattern fidelity in large area patterning is one of the obstacles to applying the hot embossing technology for mass production. In the present study, PDMS pad was used as a cushion on the backside of the micro-patterned 4 inch Si mold to improve the pattern fidelity over the 4 inch PMMA sheet by increasing the conformal contact between the Si mold and the PMMA sheet. The pattern replicability improvement over 4 inch wafer scale was evaluated by comparing the replicated pattern height and depth for PDMS-cushioned Si mold against the rigid Si mold without PDMS cushion.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.13 no.1
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• pp.77-83
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• 1995

This paper is concentrated on map generalization in digital environment for automated multi-scale map pro-duction using conventional hardcopy maps. Line generalization is urgently required process to prepare small scale digital map database when large scale map databases are available. This paper outlines a new approach to the line generalization when preparing small scale map on the basis of existing large scale distal map. Line generalizations are conducted based on zero-crossing algorithm using six sheets of 115,000 scale YEOSU area which produced by National Geographic Institute. The results are compared to Douglas-Peucker algorithm and manual method. The study gives full details of the data reduction rates and alternatives based on the proposed algorithm.

• Proceedings of the Korea Contents Association Conference
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• 2008.05a
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• pp.198-202
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• 2008

Manufacturing process of large-scale 3D computer animation is becoming sophistication, ramification because of development of manufacturing technique and extravagant budget. Form of manufacturing pipeline has been variously changed to production type, manufacturing scale, manufacturing form. But it is time that renewed discussion is needed because change and development for the organization is insufficient in small manufacturing company. The project aims to try to help understanding for manufacturing pipeline of internal small-scale 3D animation and to find a plan of organization for internal small-scale production of the real situation. Organization model and methodology of manufacturing pipeline of small manufacturing company is not absolute because it is enough possible to be changed to inclination of the project and its environment. People must fully understand the purpose for organization of manufacturing pipeline of 3D computer animation and it must be organized to the situation for small-scale production so that every worker in production can share the information perfectly.

• 한국연소학회:학술대회논문집
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• 2012.04a
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• pp.231-233
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• 2012

Circulating Fluidized Bed (CFB) is a technically and economically proven technology for boiler systems and large CFB coal boilers are making inroads into the domestic power boiler market. For biomass gasification, it is also considered as a very promising technology for commercial. Due to the lack of experiences of a large scale CFB gasifier, however, any large scale CFB gasifiers are hard to in Korea in spite of fast-growing demand of domestic market. In this study, a 3 $MW_{th}$ CFB gasifier was developed for biomass gasification. The CFB gasifier consists of interconnected fast and bubbling fluidized bed reactors including unique features for in-situ tar removal. Various numerical and experimental approaches will be presented such as basic modeling works, investigation of hydrodynamics with a cold model, computational particle fluid dynamics and experiments in the 3 MWth gasifier.

• Journal of Korean Institute of Industrial Engineers
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• v.29 no.4
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• pp.334-344
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• 2003

A mixture experiment is a special type of response surface experiment in which factors are the ingredients or components of a mixture, and the response is a function of the proportions of each ingredient. Evolutionary operation is useful to improve on-line full-scale manufacturing process by systematically changing the levels of the process variables without jeopardizing the product. This paper presents an evolutionary operation procedure with mixture variables for large-scale mixture production process which can be beneficial to practitioners who should improve on-line mixture quality while maintaining the production amount of the mixture product.

• Journal of the Korean Society of Industry Convergence
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• v.22 no.3
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• pp.293-301
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• 2019

Based on accurate image processing technology, a system for measuring displacement in ${\mu}m$ for drive error (position error, straightness error, flatness error) at a distance using parallel light and image sensor is developed, and a system for applying this technology development to a large 3D rapid prototyping machine and compensating in real time is developed to dramatically reduce the range of measurement error and enable intelligent 3D production of high quality products.