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Significance of Hemodynamic Effects on the Generation of Atherosclerosis

  • Suh Sang-Ho;Roh Hyung-Woon;Kim Dong-Joo;Kwon Hyuck-Moon;Lee Byoung-Kwon
    • Journal of Mechanical Science and Technology
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    • v.19 no.3
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    • pp.836-845
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    • 2005
  • Atherosclerosis, which is a degenerative vascular disease, is believed to occur in the blood vessels due to deposition of cholesterol or low density lipoprotein (LDL). Atherosclerotic lumen narrowing causes reduction of blood flow due to hemodynamic features. Several hypothetical theories related to the hemodynamic effects have been reported : high shear stress theory, low shear stress theory, high shear stress gradient theory, flow separation and turbulence theory, and high pressure theory. However, no one theory clearly explains, the causes of atherosclerosis. The objective of the present study was to investigate the mechanism of the generation of atherosclerosis. In the study, the database of Korean carotid and coronary arteries for geometrical and hemodynamic clinical data was established. The atherosclerotic sites were predicted by the computer simulations. The results of the computer simulation were compared with the in vivo experimental results, and then the pathogenesis of atherosclerosis by using the clinical data and several hypothetical theories were investigated. From the investigation, it was concluded carefully that the mechanism of the generation of atherosclerosis was related to the hemodynamic effects such as flow separation and oscillatory wall shear stress on the vessel walls.

A Study about Construction of Sasang Constitutional Nursing Theory: On the focus 『Dongyi Soose Bowon Sasang Chobongyun』 (체질적 간호 이론 정립을 위한 연구 『동의수세보원사상초본권(東醫壽世保元四象草本卷 )』 을 중심으로)

  • Yoo, Jung-Hee;Lee, Eui-Ju;Song, Il-Byung;Koh, Byung-Hee;Lee, Soo-Kyung;Lee, Hyang-Yeon
    • Journal of Sasang Constitutional Medicine
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    • v.16 no.2
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    • pp.71-83
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    • 2004
  • 1. Objectives The purpose of nursing is to promote health and well-being for all persons. It is connected with Sasang Constitution theory have regard for viewpoint by other's a special quality & individual difference. A nursing is helping behavior to recover health, disease protection & self care ability through health education. There is need for Oriental nursing research continually. 2. Methods This study attempted to develop a fundamental nursing theory for Sasang Constitution on the focus "Dongyi Soose Bowon Sasang Chobongyun". Because the book is important to understand Lee Je-ma's early medical mind and thinking. 3. Results and Conclusions The Sasang Constitution theory lay great emphasis upon health caring medicine to promote health according to self Constitution at normal times, preventive medicine to manage byself body and mind in ordinary times. The way of Sasang Constitutional Nursing Theory is expected to set up a landmark stone in Korean nursing. It is also can product a new nursing theory. In view of 'Nature and Order' is explained inborned general human being who were gifted from nature. On the other hand, in view of 'Knowledge and Deed' based on Constitutions are explained autonomical human being. There are depend on independant control and make efforts themselves or not. It have a connected in four paradigm (human- environment-health- nursing) of nursing theory. The history taking stage claim caring of sick-people before. The ways of assesment for sick-people have to know a process of illness.

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An original single variable shear deformation theory for buckling analysis of thick isotropic plates

  • Klouche, Faiza;Darcherif, Lamia;Sekkal, Mohamed;Tounsi, Abdelouahed;Mahmoud, S.R.
    • Structural Engineering and Mechanics
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    • v.63 no.4
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    • pp.439-446
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    • 2017
  • This work proposes an original single variable shear deformation theory to study the buckling analysis of thick isotropic plates subjected to uniaxial and biaxial in-plane loads. This theory is built upon the classical plate theory (CPT) including the exponential function in terms of thickness coordinate to represent shear deformation effect and it involves only one governing differential equation. Efficacy of the present theory is confirmed through illustrative numerical examples. The obtained results are compared with those of other higher-order shear deformation plate theory results.

A Dialectical Study of the Book Selection Theory (도서선택론의 변증법적 연구)

  • Yun Hee-Yun
    • Journal of the Korean Society for Library and Information Science
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    • v.29
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    • pp.173-204
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    • 1995
  • The purpose of this study is to promote understanding of the book selection theory by researching dialectically of its development process centering on the BSTv(value theory) and BSTd(demand theory). The results of this study are summarized as follows 1. In the period of enlightenment and education, the book selection theory of public libraries was the thesis state of BSTv(d). 2. Antithesis state of BSTv(d), that is, BSTd was raised to real central theory of book selection in the early 20th century. 3. In the 1930-40's, BSTv and BSTd were transformed into balance state or coexistence relations(BSTb $[v(d){\cdot}d(v)$]. 4. After World War II, BSTn(library needs theory) and BSTo(library objective theory) were evoked, and opposed to the existing selection theories. Now, they are developing into BSTbl$[n(d)\cdot\;o(v)\;or\;n(d){\cdot}v(o)]$.

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Axisymmetrical bending of single- and multi-span functionally graded hollow cylinders

  • Bian, Z.G.;Wang, Y.H.
    • Structural Engineering and Mechanics
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    • v.45 no.3
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    • pp.355-371
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    • 2013
  • Single- and multi-span orthotropic functionally graded hollow cylinders subjected to axisymmetrical bending are investigated on the basis of a unified shear deformable shell theory, in which the transverse displacement is expressed by means of a general shape function. To approach the through-thickness inhomogeneity of the hollow cylinder, a laminated model is employed. The shape function therefore shall be determined for each fictitious layer. To improve the computational efficiency, we resort to a transfer matrix method. Based on the principle of minimum potential energy, equilibrium equations are established, which are then solved analytically using the transfer matrix method for arbitrary boundary conditions. Numerical comparisons among a third-order shear deformable shell theory, an exact elastic theory and the present theory are provided for a simply supported hollow cylinder, from which the present theory turns out to be superior in stress estimation. Distributions of displacements and stresses in single- and three-span hollow cylinders with different boundary conditions are also illustrated in numerical examples.

A new shear deformation plate theory with stretching effect for buckling analysis of functionally graded sandwich plates

  • Mahmoud, S.R.;Tounsi, Abdelouahed
    • Steel and Composite Structures
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    • v.24 no.5
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    • pp.569-578
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    • 2017
  • In this research work, a simple and accurate hyperbolic plate theory for the buckling analysis of functionally graded sandwich plates is presented. The main interest of this theory is that, in addition to incorporating the thickness stretching effect (${\varepsilon}_z{\not=}0$), the displacement field is composed only of 5 unknowns as the first order shear deformation theory (FSDT), instead of 6 like in the well-known "higher order shear and normal deformation theories". Thus, the number of unknowns and governing equations for the present theory is reduced, significantly facilitating engineering analysis. Governing equations are obtained by employing the principle of minimum total potential energy. Comparison studies are performed to verify the validity of present results. A numerical investigation has been conducted considering and neglecting the thickness stretching effects on the buckling of sandwich plates with functionally graded skins. It can be concluded that the present theory is not only accurate but also simple in predicting the buckling response of sandwich plates with functionally graded skins.

A new simple three-unknown shear deformation theory for bending analysis of FG plates resting on elastic foundations

  • Hachemi, Houari;Kaci, Abdelhakim;Houari, Mohammed Sid Ahmed;Bourada, Mohamed;Tounsi, Abdelouahed;Mahmoud, S.R.
    • Steel and Composite Structures
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    • v.25 no.6
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    • pp.717-726
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    • 2017
  • In this paper, a new simple shear deformation theory for bending analysis of functionally graded plates is developed. The present theory involves only three unknown and three governing equation as in the classical plate theory, but it is capable of accurately capturing shear deformation effects, instead of five as in the well-known first shear deformation theory and higher-order shear deformation theory. A shear correction factor is, therefore, not required. The material properties of the functionally graded plates are assumed to vary continuously through the thickness, according to a simple power law distribution of the volume fraction of the constituents. Equations of motion are obtained by utilizing the principle of virtual displacements and solved via Navier's procedure. The elastic foundation is modeled as two parameter elastic foundation. The results are verified with the known results in the literature. The influences played by transversal shear deformation, plate aspect ratio, side-to-thickness ratio, elastic foundation, and volume fraction distributions are studied. Verification studies show that the proposed theory is not only accurate and simple in solving the bending behaviour of functionally graded plates, but also comparable with the other higher-order shear deformation theories which contain more number of unknowns.

DIGITAL COVERING THEORY AND ITS APPLICATIONS

  • Kim, In-Soo;Han, Sang-Eon
    • Honam Mathematical Journal
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    • v.30 no.4
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    • pp.589-602
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    • 2008
  • As a survey-type article, the paper reviews various digital topological utilities from digital covering theory. Digital covering theory has strongly contributed to the calculation of the digital k-fundamental group of both a digital space(a set with k-adjacency or digital k-graph) and a digital product. Furthermore, it has been used in classifying digital spaces, establishing almost Van Kampen theory which is the digital version of van Kampen theorem in algebrate topology, developing the generalized universal covering property, and so forth. Finally, we remark on the digital k-surface structure of a Cartesian product of two simple closed $k_i$-curves in ${\mathbf{Z}}^n$, $i{\in}{1,2}$.

The Theory of Thin-Walled Curved Rectangular Box Beams Under Torsion and Out-of-Plane Bending (비틀림과 평면외 굽힘을 받는 직사각단면 곡선 박판보 이론)

  • Kim, Yun-Yeong;Kim, Yeong-Gyu
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.24 no.10 s.181
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    • pp.2637-2645
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    • 2000
  • We propose a new one-dimensional theory for thin-walled curved box beams having rectangular cross sections, in which torsional, out-of-plane bending, warping and distortional deformations are coupled. The major difference between the present theory and existing theories lies in that the present theory takes into account additional distortion as well as warping. To verify the present theory, a standard finite element based on the present theory is developed and used for numerical analysis. A couple of numerical examples indeed confirm that the consideration of warping and distortional deformations is very important.

Design of 5kW-class Horizontal Axis Wind Turbine using In-house Code POSEIDON (In-house 코드 POSEIDON을 이용한 5kW급 수평축 풍력발전용 로터 블레이드 형상설계)

  • Kim, Ki-Pyoung;Kim, Ill-Soo;Choi, Young-Do;Lee, Young-Ho
    • 한국신재생에너지학회:학술대회논문집
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    • 2009.11a
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    • pp.492-492
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    • 2009
  • Nowadays in Republic of Korea, there is no distinct reference for the related design technology of rotor blade of wind turbine. Therefore the optimum design and evaluation of performance is carried out with foreign commercial code softwares. This paper shows in-house code software that evaluates the aerodynamic design of wind turbine rotor blade using blade element-momentum theory (BEMT) and processes that is applied through various aerodynamics theories such as momentum theory, blade element theory, prandtl's tip loss theory and strip theory. This paper presents the results of the numerical analysis such as distribution of aerodynamic properties and performance curves using in-house code POSEIDON.

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