• Title/Summary/Keyword: alternatives

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Estrogenic and Androgenic Potential of Phthalates and Their Alternatives (프탈레이트류와 그 대체물질의 내분비계 교란독성: 에스트로겐성과 안드로겐성을 중심으로)

  • Kwon, Bareum;Ji, Kyunghee
    • Journal of Environmental Health Sciences
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    • v.42 no.3
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    • pp.169-188
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    • 2016
  • Objectives: Although information on the toxicity of phthalate diesters is readily available, little is known about phthalate alternatives. The present article provides a summary of available information on the toxicity of phthalate diesters and their alternatives, with a special focus on estrogenicity and androgenicity. Methods: We collected a battery of in vitro and in vivo assay data from the literature to assess the estrogenicity/anti-estrogenicity and androgenicity/anti-androgenicity of 15 phthalate diesters and 21 phthalate alternatives. Results: A number of in vitro studies show that certain phthalate diesters can bind to estrogen receptors and have a weak estrogenic potential. However, this potential was not seen in in vivo studies. Phthalate diesters produced anti-androgenic effects in animals by reducing testosterone production. Among them, di-(2-ethyl-hexyl) phthalate (DEHP) was the most potent. While almost all phthalate alternatives have a lower toxic potential than does DEHP, evidence of reproductive toxicity and estrogenic potential were found in several substances. Conclusion: Significant data gaps exist for phthalate alternatives regarding reproductive endocrine disruption, requiring further investigation.

Design Alternatives and Residents' Pre-Evaluation of Village Community Center for the Aged Rural Area (고령화 농촌을 위한 마을회관 디자인 및 주민 사전평가)

  • Choi, Byungsook;Park, Sunhee;Oh, Chanohk;Kim, Jusuk
    • Journal of the Korean Institute of Rural Architecture
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    • v.10 no.3
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    • pp.9-18
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    • 2008
  • The study was intended to suggest the design alternatives of rural village community center based on the design directions which were derived from the previous research, and to evaluate the alternatives by rural residents. The previous research was carried out to grasp the conditions and user's needs of rural village community center. The subjects were 100 residents who lived in rural area in Chonlabukdo. The interview was carried out using a questionnaire with model and isometrics of two alternatives, which showed floor plan and building shape. The subjects evaluated positively both of two alternatives, but slightly more preferred alternative | because of a spacious diningroom and an indoor toilet. The size of a livingroom and entrance, indoor toilet space/location, storage space and deck were significant elements in two alternatives according to t-test. They responded that both of indoor and outdoor toilet should be planned in rural village center. Also, each toilet and room for man and woman should be separated. Entrance space should be enough to take on/off their shoes in a sitting position and deck space was planned to intermediate between indoor and outdoor space.

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Improvement of the Evaluation Method for VE Alternatives using the Risk Assessment Process (리스크 평가절차 도입을 통한 VE 대안 평가방법 개선)

  • Park, Jin-Ho;Jin, Zheng-xun;Hyun, Chang-taek;Kim, Hyun-joo;Kwon, Suk-hyun
    • Korean Journal of Construction Engineering and Management
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    • v.19 no.5
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    • pp.32-42
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    • 2018
  • Since the success or failure of VE projects depends on the capabilities of participants, including owners, construction managers, architects, general contractors and VE experts, it is important to follow systematic procedures. However, it is often the case that only a rough evaluation is performed, or the rough and detailed evaluations are integrated in actual VE tasks. In this case, it is difficult to analyze and evaluate the alternatives in terms of risk, even for the important alternatives. This in turn leads to the so-called returning alternatives where the alternatives proposed in the preceding stage are returned to the original plans in the following stage, and thus the repetitive work for the alternatives often decreases the efficiency of the VE task. In this regard, this study proposed a risk assessment process for VE alternatives in order to minimize the occurrence of returning alternatives based on the systematic analysis and evaluation of VE alternatives. It will increase the efficiency of VE tasks by reduces the number of regression alternatives.

k-Sample Rank Procedures for Ordered Location-Scale Alternatives

  • Park, Hee-Moon
    • Journal of Korean Society for Quality Management
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    • v.22 no.2
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    • pp.166-176
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    • 1994
  • Some rank score tests are proposed for testing the equality of all sampling distribution functions against ordered location-scale alternatives in k-sample problem. Under the null hypothesis and a contiguous sequence of ordered location-scale alternatives, the asymptotic properties of the proposed test statistics are investigated. Also, the asymptotic local powers are compared with each others. The results show that the proposed tests based on the Hettmansperger-Norton type statistic are more powerful than others for the general ordered location-scale alternatives. However, the Shiraishi's tests based on the sum of two Bartholomew's rank analogue statistics are robust.

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Evaluation of Investment Alternatives with Different Life Times (수명이 서로 다른 투자 대안의 평가)

  • 박홍석
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.14 no.24
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    • pp.105-109
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    • 1991
  • In the comparative study of investment alternatives with different life times. It is wrong to compare a long-life time alternative with different life times. It is to wrong to compare a long-life time alternative with a short-life time one by the same measure; therefore, a measure is needed which is suitable for the characters of alternatives. The purpose of this study is in present a method to evaluate investment alternatives with different life times and to explain the assumptions and calculating method.

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Establishment of Matlab-based MCDA Interactive Model for the Sensitivity of the Preferred Alternatives to the Number of Criteria (Matlab기반의 다중의사결정 기준 변화에 따른 민감도 분석)

  • Lim, Kwang-Suop;Lee, Dong-Ryul;Lee, Chang-Hae
    • Proceedings of the Korea Water Resources Association Conference
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    • 2009.05a
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    • pp.297-301
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    • 2009
  • The impact of adding additional Multi-Criteria Decision Analysis (MCDA) criteria is demonstrated because current research shows MCDA for flood damage has been applied using only a few criteria but for better results the MCDA approach needs to apply more criteria for evaluating the alternatives. By adding additional criteria into MCDA, the capability to make the best alternatives more diverse and show the decision maker more differences in the scores of the alternatives to allow the decision maker to discriminate is significantly improved. The target region for a demonstration application of the methodology was the Suyoung River Basin in Korea. The 1991 Gladys flood event and five different return periods were used as a case study to demonstrate the proposed methodology of evaluation of various flood damage reduction alternatives.

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Visual Impact Assessment of the Urban Landscape with Public Participation (주민참여에 의한 도시경관의 영향평가 : 서울시 중계동 아파트 계획안을 대상으로)

  • Oh, Kyushik;Lee, Yongja
    • Journal of Environmental Impact Assessment
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    • v.3 no.1
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    • pp.43-52
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    • 1994
  • This study conducted a visual impact assessment of an apartment complex project proposed in Jungkye-dong, Seoul. Three design alternatives of the project-alternatives 1, 2, and 3-which differed in form, color, scale, and arrangement of buildings were simulated with computer image processing technique. The simulations were presented to the public who were mainly residents in the project area, and visual impact resulted from the alternatives was assessed by them. Their responses were then statistically analyzed. It was found that, in terms of compatibility with the surrounding landscape, alternative 1 was the most favourable because it was more traditional, natural, and diverse than alternatives 2 and 3. At the same time, the alternative was most preferred by the public because it was more plain, natural, and diverse than other alternatives. It was suggested that the visual impact assessment with public participation conducted in this study would help both planners and the public to make more intelligent decisions.

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Dual Earner Families' Child Care Alternatives and Policy Implications (맞벌이 가족의 자녀양육방식을 통해 본 아동양육지원의 정책적 함의)

  • Kim Seon-Mi
    • Journal of Families and Better Life
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    • v.23 no.6 s.78
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    • pp.105-116
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    • 2005
  • This study investigated various alternatives for childcare among dual-earner families and discussed implications for public policy development. Eight employed married women and two of their husbands were interviewed about work-family balance. All the interviewees complained that taking cue of the children in dual-earner families is a challenge. They resort to all available alternatives because public childcare support is insufficient and inadequate. There were five different types chilcare: extended family network, public and private institutions, paid help (nannies), rearranging work schedules, and training their children to take cue of themselves. However, all these alternatives entail various problems. More and better childcare facilities and programs should be built and after-school programs should be designed. On the other hand, parents should also make more effort to prioritize children's needs in finding a balance between work and family.

A Study on Feasibility Analysis and Alternatives for Infrared Detector Development (적외선 검출기 개발가능성 및 대안분석 연구)

  • Min, Sung Ki;Kim, Chul Whan;Kim, Kyoung Su
    • Journal of the Korean Society of Systems Engineering
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    • v.1 no.1
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    • pp.1-13
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    • 2005
  • The purpose of this paper analyze development feasibility and alternatives for infrared detector development in both technology and cost. Infrared Detector is core component of Thermal Imaging System and developed by ADD from 2006 10 2008 year. We got raw input data from development and technical expert, and then analyze cost and technology for development feasibility, and alternatives study. Technology level is analyzed by TRL(Technology Readiness Level) and AOA(Analysis of Alternatives) is done by development cost estimate. Estimating the development cost, we use SEER-H that is parametric cost estimating tool based on Knowledge Base. This study can help those who are related to the cost and development feasibility analysis of other weapon systems.

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The Procedure for Selecting the Alternatives for Developers of Container Cranes (컨테이너크레인 개발자를 위한 대안 선정 절차)

  • Won, Seung-Hwan;Choi, Sang-Hei
    • Journal of Navigation and Port Research
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    • v.32 no.8
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    • pp.621-628
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    • 2008
  • Container terminals keenly compete with one another because of the continuous increase of container flows and the appearance of large-sized vessels. Major cargo handling equipment manufacturers are interested in the development of new conceptual equipment to greatly increase its productivity. In this study, a two-phase procedure is suggested for selecting the optimal development alternatives, when various development alternatives for container cranes are given. The first phase removes the alternatives that violate essential requirements and the second phase selects final alternatives by the evaluation of experts and the linear assignment method. Finally, a case applying the procedure is provided.