• Title/Summary/Keyword: allergens

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A Survey on the Recognition of Confectionery Bakers Working in Gyeongnam Province for Food Allergy (식품알레르기에 대한 경남지역 제과제빵 종사자들의 인식도 조사)

  • Kim, Sol-A;Lee, Jeong-Eun;Cho, Sung-Rae;Chang, Ji-Yoon;Shim, Won-Bo
    • Journal of Food Hygiene and Safety
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    • v.33 no.5
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    • pp.330-338
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    • 2018
  • The aims of this study were to investigate the perception of confectionery bakers working in Gyeongnam province for food allergy and to find ways to improve and manage food allergy in confectionery and bakery. The questionnaire was composed of general questions and other questions related to food allergy in confectionery and bakery, and the questionnaires were distributed to the bakers working in Gyeongnam. Sixty nine of 102 confectioneries and bakeries responded to this study, and 60 (87.0%) out of 69 people were aware or had heard about food allergy. However, 54 (78.3%) out of 69 lacked prior education about the management of food allergy. Fifty one (73.9) of 69 people responded that they strongly considered food allergy in the manufacture of the products, but they were not educated about the management of food allergens and symptoms of food allergy. Confectionery bakers were aware about food allergies, but did not label food allergen on the products and have a specific management for food allergens at the work site. Therefore, it is necessary to educate the confectionery bakers about food allergy and to develop and distribute a manage program of food allergens in the field. The result from the present study could be used as basic data for the investigation of awareness for food allergy of confectionery bakers working in Korea.

S100A8 and S100A9 Secreted by Allergens in Monocytes Inhibit Spontaneous Apoptosis of Normal and Asthmatic Neutrophils via the Lyn/Akt/ERK Pathway (단구에서 분비되는 S100A8과 S100A9의 Lyn/Akt/ERK 경로를 통한 정상인과 천식질환 호중구의 세포고사 억제 효과)

  • Kim, In Sik;Lee, Ji-Sook
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.2
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    • pp.128-134
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    • 2017
  • Der p 1 and Der p 2 are essential allergens of house dust mite associated with the development of asthma. In the present study, we examined whether Der p 1 and Der p 2 induce a release of S100A8 and S100A9 in monocytes, which are involved in the regulatory mechanism of neutrophil apoptosis. We found that Der p 1 and Der p 2 significantly increased the secretion of S100A8 and S100A9 in normal monocytes. Moreover, S100A8 and S100A9 strongly suppressed the spontaneous apoptosis of normal and asthmatic neutrophils. The inhibitory effect of S100A9 was stronger than that of S100A8, and asthmatic neutrophils showed a higher inhibitory effect than normal neutrophils. S100A8 and S100A9 induced activation of Lyn, Akt, and ERK in a time-dependent manner. These findings elucidate the roles of Der p 1 and Der p 2 in the interaction between monocytes and neutrophils, as well as contributing to our knowledge of the pathogenesis of allergic diseases.

The Clinical Observations in Childhood Asthma (기관지 천식의 초기 발병시 임상적 양상에 관한 관찰)

  • Song, Kih-Yean;Park, Yong-Hyoun;Jun, Jin-Gon;Lee, Young-Hwan;Kim, Chun-Dong
    • Journal of Yeungnam Medical Science
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    • v.9 no.2
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    • pp.239-247
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    • 1992
  • A clinical analysis was done on 134 cases with bronchial asthma who were admitted to the Department of Pediatrics Yeungnam University from May 1987 to October 1991. The results were as followings; 1) The peak age of bronchial asthma was under 2 years. The sex ratio of male to female was 2.9 : 1. 2) The out-break of bronchial asthma was most common in fall, especially in September. 3) The past history of other allergic diseases were present in 22.4% of patients(30/134 cases), and the previous bronchiolitis in infancy were experienced in 12.7% of patients(17/134 cases). 4) According to the skin test for allergens done by RAST, the most common allergens were Mites and House dust. 5) Eosinophilia(T.E.C>250/min) was found in 29.1% of patients, and elevated IgE level(>200 $IU/m{\ell}$) was found in 63.2% of patients. 6) No significant differences in the serum IgE level were found between male and female patients. No significant differences in the serum IgE level were found between asthma patients with and without other allergic diseases. 7) The serum IgE level of school aged patients was significant higher than that of preschool aged(p<0.01).

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Evaluation of Allergenicity for Fish and Method for Reduction of Allergenicity by Food Technological Treatment (생선의 Allergen성 판정과 Allergen성을 감소시키는 가공학적 방법)

  • 이부웅;장운기;오동규
    • Food Science of Animal Resources
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    • v.20 no.2
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    • pp.114-124
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    • 2000
  • In this research the results showed that Evans blue stain causes vascular permeation at antibody injection site by the passive cutaneous anaphylaxis(PCA) screening of octpus minor so we concluded. Octopus minor causes allergy. Psedosciaena Polyactis, Raja Kenojei, Metapenaeus joyneri also showed allergenicity. Microwave and autoclaving appeared to reduced allergenicity(up to 99%) during the technological treatment processing. On the other hand, UV light didn't seem to change the protein structure of allergens affect the allergenicity. Therefore, the technological treatment processing of fish such as canning and microwave would possibly reduce the allergenicity. Among the ultrafiltration fraction of Octopus minor, Pseudosciaena Polyactis, Raja Kenojei and Metapenaeus joyneri, those fraction over 100,000 contained allergen and those under 100,000 and when screening allergenic fish went through 10,000~100,000 ultrafiltration, only the fraction of over 100,000 showed the anaphylactis activity for PCA. However whether screening fish would cause anaphylaxis in human or not is questionable. The future clinical experiment will verify this result with clinical experiment patients.

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A Survey on the Actual Condition of Products not Labeled with Allergens (알레르기 유발물질 미표시 제품 실태 조사)

  • Kim, Kyung-Seon;Song, Sung-Min;Kwon, Sung-Hee;Jang, Seung-Eun;Lee, Bo-Min;Kim, Meyong-Hee;Han, Young-Sun;Hur, Myung-Je;Kwon, Mun-Ju
    • Journal of Food Hygiene and Safety
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    • v.36 no.3
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    • pp.257-263
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    • 2021
  • For this survey, PCR (polymerase chain reaction) testing was conducted using 14 species-specific primers to monitor the labeling of allergy-causing substances in various foods. Sixty samples from stationary stores near elementary schools and imported confectionery shops were tested, including snacks, candies, and chocolate. Allergens of milk, wheat, eggs, tomatoes, almonds and peanuts were detected in 30 cases (50.0%). In addition, many products were detected as either containing unlabeled substances or not showing allergen-related information and labeling in Korean. In order to ensure that consumers are able to purchase products safely and securely, a system for thorough guidance and monitoring of allergen-related labeling by domestic manufacturing and processing companies and import-related companies is required.

Analysis and Reproduction of Fragrance Components of Lavandula Angustifolia Flower and Essential Oil (라벤더 꽃과 에센셜 오일의 향기 성분 분석 및 재현)

  • Ko, Eun sung;Kim, Hyung mook;Kwak, Byeong mun;Lee, Mi Gi;Bin, Bum ho
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.47 no.2
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    • pp.93-98
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    • 2021
  • This study aims to find a discriminatory way that can lower the dependence on imports of aroma essential oils and increase the value of herb plants that are growing in domestic demand and cultivation. To this end, through a study that analyzes and reproduces fragrance components without damaging the original material of domestically grown lavender flowers using the SPME method, we are trying to confirm the difference in fragrance composition from lavender essential oil and find the fragrance originality of domestically grown herb plants. A total of 38 kinds of lavender essential oils and 27 kinds of lavender flowers were analyzed as fragrance ingredients, Among them, the common ingredients were myrcene, d-limonene, 1,8-cineol, ocimene, p-cymene, α-terpinolene, camphor, linalool, linalyl acetate, bornyl acetate, 4-terpineol, and a-terpineol. In addition, among the fragrance components of the two samples, it was confirmed that the type and content of allergens of domestically cultivated lanvender flowers were low. As a result of the sensuality evaluation of 15 panels, domestic cultivated lavender flower reproduction scent was higher in favor of lavender essential oil, which has been used in the industry until now. It is also believed that lavender fragrance, which lowers the content of allergy-causing ingredients, can expand industrialization.

Photopatch Tests of recent three years at Kyoto University Hospital

  • Katoh, Mayumi;Kitoh, Akihiko;Otoshi, Eriko;Arima, Yaeno;Nishigori, Chikako;Miyachi, Yoshiki
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.497-499
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    • 2002
  • We experienced 29 cases of tentative photo allergic disorders from April 2000 to March 2002. For those 29 patients, photopatch tests have been done to explore possible causative photoallergens. We performed photopatch tests with photo-related allergens and possible causative products that the patients brought to us. After applications for 48hrs, one test site was irradiated with half of MRD or 6.0 J/cm$^2$ of UVA. Readings were evaluated according to the reading criteria of the ICDRG. Photoallergens were suggested in 20 cases (69.0%). Among them, we could find out the causative products in 7 cases (24.1%). Photopatch tests, performed by an appropriate method, are useful in some cases not only for diagnosis of photocontact dermatitis but also diagnosis of systemic photoallergic disorders.

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Repellent effect of Eucalyptus detergent against house dust mites (Dermatophagoides farinae and Dermatophagoides pteronyssinus) (집 먼지 진드기에 대한 유칼립투스 세제의 기피효과)

  • Kim, Hye-Sung;Jee, Cha-Ho
    • Korean Journal of Veterinary Service
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    • v.38 no.2
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    • pp.83-87
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    • 2015
  • The exposure to house dust mites is closely connected with allergic diseases such as atopic dermatitis, allergic rhinitis and asthma. Control of house dust mite populations has been principally achieved by using chemical insecticides. But the risk to human health would be a potential problem. Moreover, house dust mite remain as allergens even after death. Therefore, repelling the house dust mites is more effective method than killing them. The use of plant-derived repellents has been considered as a promising alternative to chemical repellents. Eucalyptus oils are regarded as safe compounds, there have been attempts to commercialize and market the insecticides/repellent products containing Eucalyptus oil as such or based upon them. For that reason, we experimented repellent activity against these mites using laundry detergent with Eucalyptus oil in this experiment. House dust mites (Dermatophagoides farinae and Dermatophagoides pteronyssinus) were exposed at different concentrations (4, 8, 16, $32{\mu}L/mL$) in fabric treated laundry detergent with Eucalyptus oil for 24 hours. The repellent effects (%) of laundry detergent with Eucalyptus oil exposed at 4, 8, 16, and $32{\mu}L/mL$ were 48.16%, 74.62%, 52.67%, and 44.47%, respectively. These results suggest that laundry detergent with Eucalyptus oil have potential effect to repel the house dust mites.

Study of Prevalence of Symptom and Common Allergen of Allergic Conjunctivitis (알레르기성 결막염의 유병률 및 주요 알레르겐에 관한 연구)

  • Lee, Eun-Hee;Pak, Yun-Suk;Paek, Do-Myung
    • Journal of Korean Ophthalmic Optics Society
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    • v.11 no.3
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    • pp.159-164
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    • 2006
  • Our study investigated the prevalence of allergic conjunctivitis and skin prick test reactivity and type of allergen from 1352 individuals living in Gwangyang city. The prevalence of allergic conjunctivitis symptom were 40,2% of study subjects and diagnosised subjects with allergic conjunctivitis of them were 15.8%. In skin prick test, 20.2% of total subjects had at least one positive skin prick reaction and positive skin prick reaction with allergic conjunctivitis of subjects was 21.3%(n=103). Their major allergens were indoor allergen like dermatophagoides pteronyssinus, Dermatophagoides farinae.

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Anti-inflammatory Effects of Aster yomena Extracts by the Suppression of Inducible Nitric Oxide Synthase Expression

  • Kim, Ah-Yeon;Shin, Hyeon-Myeong;Kim, Ji-Soo;Shim, Hyun-Jin;Nam, Kung-Woo;Hwang, Kyung-A;Youn, Hyung-Sun
    • Biomedical Science Letters
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    • v.23 no.2
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    • pp.104-110
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    • 2017
  • Inflammation is a pathophysiological process that is known to be involved in numerous diseases. Microbial infection or tissue injury activates inflammatory responses, resulting in the induction of proinflammatory proteins including inducible nitric oxide synthase (iNOS). Aster yomena is used in traditional Korean remedies. Here, we investigated the effects of ethanol extracts of Aster yomena (EAY) on the expression of iNOS induced by ovalbumin (OVA), one of the major egg allergens, or lipopolysaccharide (LPS), a Toll-like receptor 4 agonist. EAY inhibited OVA- or LPS-induced $NF-{\kappa}B$ activation. EAY also suppressed OVA- or LPS-induced iNOS expression and nitrite production. These results suggest that EAY has the specific mechanism for anti-inflammatory responses and the potential to be developed as a potent anti-inflammatory and anti-allergic drug.