• Journal of Nutrition and Health
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• 제49권1호
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• pp.8-17
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• 2016

Purpose: The aim of this study is to summarize and report on the change of food allergy in elementary school students and perception and practices in school nutritionists in Korea from 1995 to 2015. Methods: The search strategy was "(food allergy AND elementary school AND Korea) AND (nutritionist OR perception OR practice)". The search was conducted via KISS, DBPIA, RISS, NDSL, PubMed, Scopus, and Google scholar and full text and abstracts on the topic of food allergy evaluating prevalence, allergen, symptom, perception and practices were included in this review. Results: Out of 1379 records found in the sources, 13 related studies were included in the final analysis. The results showed that the number of students who had experienced food allergy was increasing. The two frequent allergenic foods were eggs and milk. The perception and practices of food allergy in school nutritionists was gradually increased. Conclusion: Further objective evaluations are required to confirm the food allergy status and its management in school.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2006년도 춘계학술대회
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• pp.115-115
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• 2006

• 한국식품영양과학회지
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• 제30권3호
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• pp.500-504
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• 2001

Gamma irradiation was applied to reduce egg allergy. Ovalbumin (OVA), an egg white protein, was used as model allergen and was gamma-irradiated at 3, 5, or 10 kGy in an aqueous state (2.0 mg/mL). The changes in allergenic and antigenic properties of OVA resulted from gamma irradiation were monitored by ELISA with serum from egg-hypersensitive patients (H-IgE), and mouse monoclonal IgG (M-IgG) or rabbit polyclonal IgG (R-IgG). The binding ability of H-IgE to irradiated OVA was dose-dependently reduced. However, IgGs from animal did better recognize 3 or 5 kGy-irradiated OVA. In the evaluation of immune reactivity using blind test, the reactivity of H-IgE rapidly decreased depending upon the irradiation dose. However, the reactivities of M-IgG and R-IgG was higher at 5 and 3 kGy-irradiated OVA than non-irradiated control. The results provide a new possibility to use irradiation process for reducing the allergenicity of egg white.

• 한국환경보건학회지
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• 제33권6호
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• pp.497-501
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• 2007

The objective of the study is to determine the contents of total chromium, water-soluble chromium and hexavalent chromium in cements and concretes specimens taken from manufacturing or construction sites. Chromate is an allergen that is widespread in the environment and is richly contained in cements. Metals were extracted with microwave oven and analyzed by atomic absorption spectrometer. Hexavalent chromium was analysed by ion chromatography. The concentrations of total chromium, water-soluble chromium and hexavalent chromium in cements were $36.02{\sim}108.01,\;15.95{\sim}89.01\;and\;26.77{\sim}89.61\;mg/kg$, respectively. The concentrations of hexavalent chromium in cements were higher than 2 mg/kg, a maximum value recommended in Northern European Countries. The concentrations of total chromium, water-soluble chromium and hexavalent chromium in concretes were $17.44{\sim}76.25,\;0.98{\sim}17.71\;and\;ND{\sim}24.13\;mg/kg$, respectively. Especially Hexavalent chromium was detected only from concrete specimens from construction sites. It is oxidized or reduced status by environmental condition or surrounding materials.

• Parasites, Hosts and Diseases
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• 제45권3호
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• pp.239-243
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• 2007

Many allergists are currently focusing on the development of new diagnostic tools, and are attempting to improve both the sensitivity and specificity. A multiple allergen simultaneous test-chemiluminescent assay (MAST-CLA) is one of the most popular diagnostic tools used in the Republic of Korea. However, there remains controversy among allergists with regard to the cut-off point for a positive result. The present study was conducted in order to determine the validity of MAST-CLA as compared with that of the skin prick test, with particular emphasis on arthropod allergens, on the basis of percentage agreement rates and k-values, and also to suggest the optimal positive cutoff points using receiver operating characteristic (ROC) curves. The study was conducted with 97 subjects (54 men, 43 women). Optimal individual cut-off points were calculated as follows; class II for Dermatophagoides farinae, class I for Dermatophagoides pteronyssinus, and trace for a cockroach mix. These findings suggest that attempting to apply optimal individual cut-off points will be a good way of improving diagnostic tests, particularly MAST-CLA.

• Journal of Dairy Science and Biotechnology
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• 제31권1호
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• pp.67-73
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• 2013

Food allergy is defined as adverse reactions toward food mediated by aberrant immune mechanisms. Cow's milk allergy is one of the most common food allergies in childhood. This allergy is normally outgrown in the first year of life, however 15% of allergic children remain allergic. Cow's milk allergy seem to be associated with casein (${\alpha}_{s1}$-CN), ${\beta}$-lactoglobulin and whey protein. In addition to this, many other milk proteins are antigenic and capable of inducing immune responses. Various food processing affects the stability, structure and intermolecular interactions of cow milk proteins, as a result reduction the allergenic capacity. Heating, hydrolysis, chemical, proteolytic and other processes such as gamma-ray irradiation, high pressure, using probiotics treatments of milk to obtain hypoallergenic milk have been developed to reduce allergic reactions.

• 한국임상수의학회지
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• 제34권4호
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• pp.245-248
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• 2017

Modified rush ASIT protocol has been performed to identify the ideal schedule that allows the dose considered effective to be reached in the shortest possible time with the fewest adverse effects. Ten atopic dogs of this study includes fulfillment of Favrot's criteria. Offending allergens were identified by the use of IDST. During the induction period, the dogs were received a total of 15 injections. Ten injections were administrated every 30 minutes in a day with gradually increasing amounts and concentrations of allergens, and the last 5 injections were administered every 3 days. Disease severity was quantified by using the canine atopic dermatitis extent and severity index (CADESI). During induction period, reduction rate from baseline scores varied between 1% and 67% and the improvement of ${\geq}50%$ was recorded after induction period of therapy for CADESI-03 score in 6 of the 10 dogs. This study of ten dogs with atopic dermatitis provide evidence for the efficacy and safety of modified rush ASIT for clinical improvement.

• 대한본초학회지
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• 제20권2호
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• pp.35-42
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• 2005

Objective : This study was performed to investigate the effect of oral administration of Oldenlandiae Diffusae Herba (ODH) on eosinophil, immunoglobulin-E and interleukin-4 in the experimental asthma induced by ovalbumin. Methods : Asthma was induced to Balb/c mouse by i.p. injection and aerosol immunization with ovalbumin. It was observed the change of the eosinophil number in the BALF. And, it was observed the change of the concentrations of IL-4 in BALF and splenocyte, IgE in serum by ELISA. Results : 1. The number of eosinophil in BALF was significantly decreased in ODH group copared with control group. 2. Concentration of IL-4 in serum, BALF and splenocyte was significantly decreased in ODH group compared with control group, respectively. 3. Level of IgE in serum was significantly decreased in ODH group compared with control group. Conclusion : We found that the effect of ODH extract in asthma was implicated in reductions of IL-4 released from Th2 cell, and decreases of IgE from plasma cell. These findings suggest that ODH extract can produce anti-asthmatic effect, which may playa role in allergen-induced asthma therapy.

• 한국식품영양학회지
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• 제19권3호
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• pp.267-270
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• 2006

한국에서 옻나무(Rhus verniciflua)는 전통적으로 약용식물로 오랫동안 사용되어 왔다. 민간요법으로 위장병 치료를 목적으로 옻나무껍질을 닭과 함께 넣어 끊여서 백숙형태로 옻닭으로 식용하였다. 그러나 일부 사람에게서 피부발진이 발생하는 극심한 알러지 반응을 일으키는 나무로 인식되어 왔다. 알러지 발생을 유발시키는 우루시올은 옻나무의 수지상 옻칠 액의 주성분이다. 이 성분의 화학적 구조는 카테친의 기본구조에 알킬기인 불포화지방산(C$_{15}_{\sim}_{17}$)이 곁사슬로 붙어 있다. 곁사슬의 불포화지방산 성분은 칠기의 고분자화 및 경화과정에 중요한 역할을 하며, 옻칠공예품의 색상 및 품질에 커다란 영향을 미친다. 한국에서 생산되는 원주산 옻칠액의 우루시올성분은 역상 컬럼을 사용하여 고속 액체 크로마토그라피 (HPLC)법으로 정제하여 ESI(-), FAB(+) 질량분석기(MS)로 분석한 결과 분자량 340인 Hetadecatetetraenyl catechol 이었다.

• 한국대기환경학회지
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• 제22권5호
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• pp.719-723
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• 2006

House dust mite was the most important cause of allergic asthma and rhinitis. More than 70% of Korean children and about 50% of adult with respiratory allergy were sensitive to house dust mite. This experiment was indoor environment in house and house dust mite existence inquiry. From 23rd December 2005 to 28th February 2006, dust samples were collected from the bedclothes by a vacuum cleaner and air sampler And the levels of Der f1 and Der p1 were determined by ELISA((Enzyme-Linked Immunosorbent Assay). The results were as follows : 1 The dust mites allergy contaminations of bedclothes in house were higher than international standards(2000 ng/g). 2. In type of dust mite, the Korean house the almost have the D. farinae other than D. pteronyeeinus of mite. 3. The Der f1 and Der p1 levels per gram of dust from the bedclothes were 2074.99 ng on average, but they did not exist in air. The concentrations of house dust mite were significantly high in the bedclothes. This results suggest that the bedclothes have enough concentrations of dust mites to develop the sensitization. The control of indoor environment should be emphasized to prevent the sensitization by the repeated exposure to dust mite.