• 생명과학회지
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• 제16권7호
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• pp.1112-1118
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• 2006

돼지 위축성 비염과 개의 kennel cough의 원인균인 B. bronchiseptica는 각 숙주의 상부 호흡기관의 점막에 집락을 형성하는 병원균으로서 철이 부족한 환경에서 hydroxamate type의 alcaligin이 라는 siderophore를 생산한다. Alcaligin의 생합성에 관련하는 구조유전자 중 alcA 유전자의 기능을 밝히고자 alcA 결손돌연변이주 구축을 통하여 확인하였다. alcA 유전자 결손 돌연변이를 위해 0.6 kb alcA 5' flanking DNA와 0.7 kb alcA 3' flanking DNA fragment들을 pCP1.11을 주형으로 하여 PCR법으로 증폭한 후, 5' flanking과 3' flanking DNA가 연결된 재조합 suicide vector pDMl을 구축하여 세포 접합을 통해 B. bronchiseptica로 도입시켰다. 도입된 pDM1으로부터 allelic exchange법에 의해 alcA 유전자가 결손된 돌연변이주 B. bronchiseptica H1을 얻을 수 있었다. B. bronchiseptica H1은 야생형인 B. bronchiseptica에 비하여 alcaligin siderophore를 거의 생성하지 못하였다. alc 오페론 중 promoter와 alcA 유전자만을 가지는 재조합 플라스미드를 B. bronchiseptica Hl에 도입하였을 때 alcaligin siderophore의 생산이 회복됨을 확인할 수 있었다. 이상의 결과로부터 alcA 유전자가 alcaligin 생합성에서 매우 중요한 역할을 수행하는 것을 알 수 있었다.

• 한국건설순환자원학회논문집
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• 제7권3호
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• pp.70-76
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• 2012

ALC의 탄산화를 분석 평가하기 위하여 비중을 0.4, 0.5 및 $0.7g/cm^3$로 제어하였으며, 이중 $0.5g/cm^3$ ALC에 실리케이트 및 실록산계 발수제를 표면 도포하였다. 또한 슬러리에 실리콘 오일 발수제를 첨가하여 ALC를 제조하기도 하였다. ALC의 탄산화는 비중과 밀접한 관련이 있었으며, ALC의 비중이 높아짐에 따라 탄산화도는 감소하였다. 이는 ALC 조직이 치밀할수록 $CO_2$ 가스의 침투가 어려워지기 때문이다. 실리케이트 및 실록산계 발수제를 표면 도포한 ALC에서는 Ref. ALC 보다 탄산화 저항성이 우수하였다. 또한 슬러리에 실리콘 오일을 첨가한 ALC에서 가장 우수한 탄산화 저항성을 나타내었다.

• 한국세라믹학회지
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• 제48권6호
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• pp.595-599
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• 2011

ALC(Autoclaved Lightweight Concrete) is produced using quartz sand, lime and cement and water. And aluminum powder is used for blowing agent. ALC is manufactured by autoclave chamber under high-temperature and high-pressure. Generally, ALC is 1/4 levels lighter than concrete and mortar, because it has a lot of pores. So density of ALC is about 0.45~0.65 g/$cm^3$. But, ALC has a weakness, typically low strength, with its porous structure. So, it is necessary to excellent strength properties for extensive apply of ALC materials in high porosity. In this study, melamine resin was used to improve the strength characteristics of ALC materials. We performed compressive and bending strength measurements. Compressive strength of ALC with 2% melamine resin increased 26.88% than 'melamine-free' ALC. Also we performed functionality evaluation such as thermal conductivity, sound absorption, and flame-resistance.

• Archives of Pharmacal Research
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• 제27권6호
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• pp.676-681
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• 2004

Acetyl-L-camitine (ALC), a naturally occurring endogenous compound, has been shown to improve the cognitive performance of patients with senile dementia Alzheimer＇s type, and to be involved in cholinergic neurotransmission. Because ALC is an endogenous compound, valida-tion of the analytical methods of ALC in the biological fluids is very important and difficult. This study was presented validation and correction for plasma ALC concentrations and pharmacok-inetics after oral administration of ALC to human volunteers. ALC concentrations in human plasma were corrected by subtracting the concentration of blank plasma from each sample. Precision and accuracy (bias %) for uncorrected ALC concentrations were below 2.6 and 6.5% for intra-days, and 4.0 and 9.4% for inter-days, respectively. Precision and accuracy (bias %)for corrected ALC concentrations were below 10.9 and 6.0% for intra-days, and 10.5 and 16.9% for inter-days, respectively. Quantitation limit was $0.1{\;}\mu\textrm{g}／mL$. After oral administration of a 500 mg ALC tablet to 8 healthy volunteers, the principle pharmacokinetic parameters were 4.2 h of the half-life$ (t_{1/2},{\beta})$, the area under the curve $(AUC_{0{\rightarrow}8){\;}of{\;}9.88{\;}\mu\textrm{g}{\cdot}h/mL$, and 3.1 h of the time ($T_{max}$) to reach $C_{max}$. This study first describes the pharmacokinetic study after oral admin-istration of a single dose of ALC in human volunteers.

• 한국토양비료학회지
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• 제31권4호
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• pp.368-372
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• 1998

한국산 잔디를 미사질 식양토에 경량기포 콘크리트 부산물(ALC)를 2.0, 4.0, $6.0Mg\;ha^{-1}$의 처리구별로 시용하고 재배하였을 때 잔디의 생육상태, 무기양분의 흡수와 수량 및 시험후의 토양의 화학적 성질변화에 미치는 영향을 포장시험에 의하여 조사한 결과는 다음과 같다. 잔디 이식 180일 후의 지상포복졍의 총길이, 지상포복경수 및 지상포복경수당 길이는 ALC $2.0{\sim}6.0Mg\;ha^{-1}$구에서는 증가하였고 $8.0Mg\;ha^{-1}$구에서는 감소하였다. 잔디 수확후의 생체중과 건물중은 ALC $6.0Mg\;ha^{-1}$구에서 가장 많았고 $8.0Mg\;ha^{-1}$구에서는 오히려 감소하였으며 ALC 처리구간에 유의성이 인정되었다. 수확기에 잔디의 무기성분 중 Si와 Ca는 ALC 처리량이 많을수록 높았고 기타성분은 차이가 크지 않았다. 시험후의 토양의 pH는 특히 ALC 시용량이 많을수록 pH는 5.7~6.4까지 상승하였으며 Si는 $19{\sim}28Mg\;ha^{-1}$ 수준으로 높았다.

• 한국세라믹학회지
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• 제49권6호
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• pp.535-541
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• 2012

ALC was fabricated using cement, lime, quartzite and a foaming agent via a hydrothermal reaction. ALC has various hydrothermal reaction products and many pores. The properties and colors of ALC surfaces were changed by various factors during ALC fabrication process. This study tested various staying times to analyze these phenomena. It was found that the staying time of green body influenced the properties of hydrothermal products and color of ALC surface. The longer staying time of green body, the lower tobermorite content and cumulative loss weight. An increase in holding time changed color and decreased whiteness of ALC surface. The relationship between whiteness and cumulative loss weight was very high (Coefficient, r = 0.95). It was surmised that tobermorite content was an important factor for enhancement of whiteness However, ettringite and quartzite did not contribute to whiteness.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2007년도 추계 학술논문 발표대회
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• pp.79-82
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• 2007

Recently, the use of ALC has became increasingly popular. ALC is a unique building material. Because of its cellular nature, it is lightweight, self-insulating, sound and fireproof, as well as insect and mold resistant. Furthermore, ALC is free of VOCs and various fibers associated with wood and glass wool construction. However, ALC have high water absorption, low compressive strength and popout the origin of the low surface strength in its properties. These properties make troubles under construction such as cracking and popout. Thus, this study is to improve the fundamental strength by controls of increasing of admixtures, and grain size. Admixtures make use of metakaolin, silica fume, sodium silicate and sodium hydroxide. From the test result, the ALC using admixture have a good fundamental properties compared with plain specimen. Compressive strength, specific strength and abrasion's ratio were improved depending on increasing admixtures ratio's, and grain size.

• 한국건축시공학회지
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• 제15권1호
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• pp.1-7
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• 2015

본 연구의 목적은 ALC 블록대체를 위한 고성능 기포콘크리트 배합설계를 개발하는 것이다. 대기양생 하에서 기포콘크리트의 고강도 발현(특히 초기재령에서)을 위하여 결합재 및 혼화제를 사전연구에서 다음과 같이 설계하였다. 규산3칼슘이 60% 이상인 보통포틀랜드시멘트에 무수석고 3%를 첨가하였으며, 폴리카르본산계 감수제에서 폴리알킬에테르 성분을 28%로 조절하였다. 이들 재료를 사용하여 물-결합재비와 단위결합재양을 변수로 기포콘크리트 11배합을 실험하였다. 배합된 기포콘크리트의 품질 및 실용성은 KS 규격의 ALC 블록의 요구조건 및 기존의 일반 기포콘크리트와 비교하였다. 실험결과 본 연구의 고성능 기포콘크리트는 ALC 블록의 요구조건을 만족하면서 높은 실용가능성을 보였다.

• 한국디지털건축인테리어학회논문집
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• 제12권4호
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• pp.87-95
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• 2012

Autoclaved lightweight concrete (ALC), also known as autoclaved aerated concrete (AAC), is a lightweight, precast building material that simultaneously provides structure, insulation. ALC is a unique building material. Because of its cellular nature, it is lightweight, self-insulating, as well as sound and fireproof. ALC products include blocks, wall panels, floor and roof panels, and lintels. Recently, the use of ALC has became increasingly popular. However, ALC have high water absorption, low compressive strength and popout the origin of the low surface strength in its properties. Thus, this study is to improve the fundamental strength by controls of increasing of admixtures and chemical reactants. Admixtures make use of meta kaolin and silica fume, chemical reactants make use of sodium silicate and sodium hydroxide. From the test result, the ALC using admixtures and chemical reactants have a good fundamental properties compared with plain ALC. These good fundamental properties is caused by the admixtures and chemical reactants of ALC by the reason of the micro filling effect and chemical binding of C-S-H gel, tobermolite and quartz.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1993년도 가을 학술발표회 논문집
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• pp.65-70
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• 1993

The effect of particle size of Al powder, water repellent agent and finishing agent on frost resistance, absorption ratio and structure of micropore was examined to improve the physical properties and durability of ALC. According as the amount added of water repellent agent was increased, frost resistance was improved and absorption ratio was decreased. From one side freezing /thaw test, finishing agent which has a low vapor permeation located the crack at close indoor point of ALC specimen. ALC produced from fine Al powder has a low volume reduction by scalling and a sound appearance after freezing/thawing test and top surface freezing test, The crystal of tobermorite in ALC matrix was converted to calcium carbonate by carbonation which was accelerated with the decreasing of water content. Since the micropore of ALC was filled up by calcium carbonate, void ratio was reduced and crack was detected after complete carbonation.