• Title/Summary/Keyword: alarming level

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Molecular phylogenetic relationships within the PSP producing marine dinoflagellate, genus Alexandrium

  • Kim, Choong-jae;Kim, Sook-Yang;Kim, Kui-Young;Kang, Young-Sil;Kim, Hak-Gyoon;Kim, Chang-Hoon
    • Proceedings of the Korean Aquaculture Society Conference
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    • 2003.10a
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    • pp.136-137
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    • 2003
  • The marine dinoflagellate genus Alexandrium has been recognized as the most representative toxic phytoplankton on account of production of paralytic shellfish poisoning (PSP) throughout the world. PSP producers, generally A, tamarense and A. catenella, within the genus Alexandrium have caused high level intoxicauon of fisheries products and even death of human. In addition, more recent increasing of geographical range of this deleterious species has given rise to alarming tension. The study presented here aimed construction of the molecular phylogenetic relationships through sequences-determination from 16 morphotypic species (containing newly sequenced 3 morphotypic species, A. tamiyavainchii, A. fraterculus and A. pseudogonyaulax) in LSU rDNA D1-D2 and 12 morphotypic species (containing newly sequenced 6 - morphotypic species, A. catenella, A. tamiyavanichii, A. fraterculus, A. affine, A. insuetum and A. pseudogonyaulax) in SSU rDNA region, and the sequences were subjected to comparative-analysis in respect to regional population using functionally expressed rDNA genus and pseudogenes. And we discussed on genetic differentiation between A. tamarense and A. catenella together with putative PSP divegence of the genus Alexandrium. The results of phylogenetic analysis showed the robust monophyletic 14 distinct classes of A. tamarense, A. excavatum, A. catenella, Tasmanian A. tamarense, A. affine (and/or A. concavum), Thai A. tamarense, A. tamiyavanichii, A. fraterculus, A. margalefii, A. andersonii, A. ostenfeldii, A. minutum (and/or A. lusitanicum), A. insuetum, and A, pseudogonyaulx clade. A. fraterculus and A. tamiyavanichii were sister relationship and they were positioned independently between A, affine cluster and those of A. margalefi, A. andersonii, A. ostenfeldii, A. minutum and A. insuetum. A. pseudogonyaulax appeared to be an ancestral taxon among Alexandrium.

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Potential of Social Media as a Channel for Film Marketing : Focusing on the Case of the Documentary Film (영화 마케팅 채널로서 소셜미디어의 가능성: 다큐멘터리 영화 <땅의 여자> 트위터 마케팅 사례를 중심으로)

  • Ahn, Ji-Hye;Min, Byung-Hyun
    • The Journal of the Korea Contents Association
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    • v.11 no.6
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    • pp.228-241
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    • 2011
  • This study aims to consider the effects of the change in communication culture affected by 'Social Media' on the film marketing. Particularly, Twitter, a kind of Social Media which shows the most rapid growth recently, is examined for what kind of benefits it's functional characteristics would provide for film marketing. Twitter, which has distinctive characteristics such as free access, the high level of attention resulting from its simplicity, alarming speed of spreading information and low costs, offers a variety of marketing opportunities not only for general commercial films but for low budget or independent films that do not have sufficient marketing opportunity. In the case of the documentary film (2010, Woo-jung Kwon), starting from the process of the film production through release to the time after the screening, it continued to communicate with potential audiences via Twitter and tried every tool of film marketing like advertising, PR, promotion and word of mouth. By doing so, it provides a model for low budget or independent films about what alternative activities they might be able to conduct for film marketing.

Development of a Control Algorithm for Automatic Ventilation (환기창 자동제어용 제어 알고리즘 개발)

  • 박규식;이기명
    • Journal of Bio-Environment Control
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    • v.6 no.4
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    • pp.242-249
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    • 1997
  • Environmental control operations have been considerably contributed to the reduction of labor cost in both plastic film and glass greenhouses since government supported projects were begun. However, some problems are still remaining on the optimal environmental control and excessive operation due to an inflexible software regulating ventilation gear - reducers. The unadjustable software caused the damage of ventilation system, resulting in heat stresses of crops. This study was performed to develop a ventilation software controlling the vent opening level, opening sequence, based on the wind direction, and control interval according to the difference between ambient and set- up temperatures. The software included a beeper system alarming urgent cases, while a manager was remote from the greenhouse. A compatible hardware with the software was also developed by using a low-cost diffused DSP controller.

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Evaluation Model of Business process Contextual Situations using goal-scenario (목표 시나리오를 이용한 비즈니스 프로세스 외부상황 평가 모델)

  • Baek, Su-Jin;Ko, Jong-Won;Song, Young-Jae
    • The Journal of the Korea Contents Association
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    • v.11 no.8
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    • pp.43-50
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    • 2011
  • The scope of the problems that could be solved by monitoring and the improvement of the recognition time is directly correlated to the performance of the management function of the business process. However, the current event-managing monitoring system and the real-time advanced alarming business monitoring system decided whether to apply warnings or not by assuming a fixed environment and showing expressions based on the design rules. Therefore, there is a limit for distinguishing the range of occurrence and the level of severity in regard to the new external problems occurring in a complicated environment. Such problems cannot be abstracted. In this paper, evaluation model of business process contextual situations using goal scenario is suggested to provide constant services through the current monitoring process in regard to the service demands of the new scenario which occurs outside. The new demands based on the outside situation are analyzed according to the target scenario for the process activities. Also, a similar process model is found and identified by combining similarity and interrelationship. The process can be stopped in advance or adjusted to the wanted direction.

Impact of Pig Slurry from WangGoong Farm Cluster on Water Quality of the Iksan Stream

  • Choi, Hong-Lim;Suresh, A.;Babu, T.;Mansyur, Mansyur
    • Journal of Animal Science and Technology
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    • v.53 no.6
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    • pp.549-561
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    • 2011
  • Livestock wastewater is being discharged without treatment from Hasen's pig farm cluster in WangGoong (WG) area into the Iksan Stream, eventually flowing into the ManGyung (MG) at the upstream junction. Although it is well known that before discharge, wastewater must satisfy the pig slurry discharge standards; because of ongoing remodeling, proper treatment is not being performed. According to public records, wastewater from the WG pig farm cluster is responsible for 3.6% of MG River pollution and 2.0% of the SaeManGuem (SMG) Reservoir pollution. As a result, upstream water treatment quality has become primary concern for development of the SMG project. All physicochemical constituents and pathogenic microbes, such as chemical oxygen demand ($COD_{Cr}$), biochemical oxygen demand ($BOD_5$), total suspended solids (TSS), total nitrogen (TN), total phosphorous (TP), fecal coliforms, Escherichia coli and Salmonella at the effluent of WG Plant (S-1) exceed the effluent standards. This is mainly due to insufficient wastewater treatment: the WG Plant is under renovation to increase water purification efficiency. By comparing the water quality at the S-7 junction, where the the Iksan Stream (pig farms) and the Wanggoong Stream (no pig farms) merge, it is clear that farming facilities and improper treatment can critically affect surrounding water quality. While it is clear throughout this study that the level of all physicochemical parameters and pathogenic microbes along the Stream decreased due to sedimentation, biodegradation and/or dilution. An alarming problem was discovered: the existence of pathogenic microbe count(E coli, Salmonella) in the lagoon wastewater and the stream water. Not only were high concentrations of these pathogens themselves found, but the potential existence of more serious pathogens could rise to more dangerous conditions.

A Study on the Co-Relation of Organizational Culture and Organizational Commitment Among Startup Companies Employees (신생기업 임직원들의 조직문화와 조직몰입의 상관관계에 관한 연구)

  • Bokhari, Syed Asad Abbas;Aftab, Muhammad;Shahid, Manzoor
    • Industry Promotion Research
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    • v.6 no.4
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    • pp.95-103
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    • 2021
  • Startup enterprises are expanding at an alarming rate in both industrialized and developing countries simultaneously. Many difficulties confront young entrepreneurs in terms of organizational and human resource management. As a result, it is critical to research startup enterprises because they have received little attention from the scientific community. In this study, we solely considered new startup enterprises operating at the small and medium-sized enterprise (SME) level in a developing country (Pakistan). The information was gathered through a survey method from ten businesses located in the metropolitan metropolis of Lahore. The correlation analysis was conducted to determine whether or not the hypothesized relationship between research variables was true. We discovered a positive and statistically significant association between all of the proposed hypotheses. The findings of this study have significant implications for industry, academics, and policymakers.

Malware Detection Via Hybrid Analysis for API Calls (API call의 단계별 복합분석을 통한 악성코드 탐지)

  • Kang, Tae-Woo;Cho, Jae-Ik;Chung, Man-Hyun;Moon, Jong-Sub
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.17 no.6
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    • pp.89-98
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    • 2007
  • We have come a long way in the information age. Thanks to the advancement of such technologies as the internet, we have discovered new ways to convey information on a broader scope. However, negative aspects exist as is with anything else. These may include invasion of privacy over the web, or identity theft over the internet. What is more alarming is that malwares so called 'maliciouscodes' are rapidly spreading. Its intent is very destructive which can result in hacking, phishing and as aforementioned, one of the most disturbing problems on the net, invasion of privacy. This thesis describes the technology of how you can effectively analyze and detect these kind of malicious codes. We propose sequencial hybrid analysis for API calls that are hooked inside user-mode and kernel-level of Windows. This research explains how we can cope with malicious code more efficiently by abstracting malicious function signature and hiding attribute.

CA 15-3 (Mucin-1) and Physiological Characteristics of Breast Cancer from Lahore, Pakistan

  • Begum, Mumtaz;Karim, Sajjad;Malik, Arif;Khurshid, Rukhshan;Asif, Muhammad;Salim, Asmat;Nagra, Saeed Ahmed;Zaheer, Ahmad;Iqbal, Zafar;Abuzenadah, Adel Mohammed;Alqahtani, Mohammed Hussain;Rasool, Mahmood
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.10
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    • pp.5257-5261
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    • 2012
  • Background: High incidence of breast cancer and its fatal effect has reached an alarming stage across the globe, including the third world countries. Many factors have been reported to be associated with the development of breast cancer but detailed structural and functional information is missing. CA 15-3 is one of the known potential tumor marker of breast cancer; however little is known about structure and functional site of this protein. Present study aims to investigate the functional role of CA 15-3 in breast cancer, especially in development and metastasis. Material and Methods: Hundred female breast cancer patients confirmed by histopathological reports were included in the study. Their physiological characters were recorded in a performa. Enzyme linked immunosorbent assay (ELISA) technique was used to estimate serum CA 15-3 level. Immunohistochemistry was done for estrogen (ER), progesterone (PR) and Her2/neu receptors expression. Results: The study revealed the details of physiological characteristics of female breast cancer. Mean age was $37.72{\pm}5.99$ and $55.05{\pm}7.28$ years and serum CA 15-3 (MUC1) level was $60.47{\pm}8.59$ and $63.17{\pm}4.58$ U/ml in pre and post-menopause respectively, and both groups of women had sedentary life style. Their receptor status especially of progesterone, estrogen and HER-2/neu were positive in 50% of premenopausal women and 65% of postmenopausal women. Conclusion: There are multiple physiological factors promoting breast cancer. High serum CA 15-3 level and hormonal imbalance of ER, PR and Her2/neu appears to be the main cause of breast cancer. It may be possible that the functional sites of these proteins may be altered which may increase the chances of metastasis in breast cancer.

Transduced PEP-1-Grb7 Fusion Protein Suppressed LPS-induced COX-2 Expression

  • An, Jae-Jin;Kim, So-Young;Lee, Sun-Hwa;Kim, Dae-Won;Ryu, Hea-Jin;Yeo, Seung-Il;Jang, Sang-Ho;Kwon, Hyung-Joo;Kim, Tae-Yoon;Lee, Sang-Chul;Poo, Ha-Ryoung;Cho, Sung-Woo;Lee, Kil-Soo;Park, Jin-Seu;Eum, Won-Sik;Choi, Soo-Young
    • BMB Reports
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    • v.40 no.2
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    • pp.189-195
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    • 2007
  • Although the incidence and severity of atopic dermatitis (AD) is steadily increasing at an alarming rate, its pathogenic mechanisms remain poorly understood yet. Recently, we found that the expression of Grb7 protein was markedly decreased in AD patients using proteomic analysis. In the present study, human Grb7 gene was fused with PEP-1 peptide in a bacterial expression vector to produce a genetic in-frame PEP-1-Grb7 fusion protein. The expressed and purified PEP-1-Grb7 fusion proteins transduced efficiently into skin cells in a time- and dose-dependent manner when added exogenously in culture media. Once inside the cells, the transduced PEP-1-Grb7 protein was stable for 48 h. In addition, transduced PEP-1-Grb7 fusion protein markedly increased cell viability in macrophage RAW 264.7 cells treated with LPS by inhibition of the COX-2 expression level. These results suggest that the PEP-1-Grb7 fusion protein can be used in protein therapy for inflammatory skin disorders, including AD.

The relationship between the major market-based media and the government in Korea (한국의 민주화와 미디어 : 정부와 시장 주류 미디어의 관계)

  • Jo, Hang-Je
    • Korean journal of communication and information
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    • v.16
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    • pp.168-206
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    • 2001
  • This study attempts to examine the relationships between the major market-based media and the government after closing military regime era, 1961-1987. After the military regime was collapsed, while the mass media in Korea obtained independence and autonomy from government, they have been confronted with the terrible competition not so much comparatively as before. The watchdog role in the traditional liberalism, which is regarded as normative relationship between the media and the government would be transformed in accordance with the market condition and the maturity of democracy. Thus, the watchdog metaphor has been variously deviated in rower-centered society; lap dog, guard dog, attack dog. liberalists argue that the primary democratic role of the media is to art as a public watchdog overseeing the state. Social democrats, however, criticize them as simplistic conception which could be only applied to the government. They argue that the media should be seen as a source of redress against the abuse of all forms of power over others; the home, the economy, and the civil society. The lap dog view is that the media is overwhelmingly dependent on the established power structure contrary to the watchdog. While the guard dog perspective is a means to preserve the power structure alarming with playing 'conflict role', the attack do8 aims to the private interest of the media in intruding into the politics. The attack dog perspective by T. Patterson could be composed of the interpretive style of report, the game schema report over the policy schema in the election, and the negativism against politics and government. The market-dominant press has been likely to transform from lap-guard dog into attack-guard dog. In Roh Tae Woo government(1988-1992), while the press was a lessened lap-guard dog before three parties merger in 1990, after merger the press had been transformed as the reinforced lap-guard dog because this merger entailed joint, party-to-party negotiations, and the formation of the new party preceded by dissolution of the ruling blot. In the early stage of Kim Young Sam government(1993-1997), the press has kept in pace with the reform movement drive-forced by the government. However, the press withdrew the support of Kim's reform in reaching the level of threat to ruling bloc. The press coalesced only circumstantially with government and was interested in preserving some margin of independence. The failure of Kim's reform proved the political muscle of the press in post-autho-ritarianism. In the middle stage of Kim Dae Jung government (1998-) that resulted in the shift of power structure as once-opposition party leader, the stress has been a manifested attack-guard dog owing to the anti-cold war policy, the realignment policy of power, and the minority-base of Kim's government. The press has endeavored to hold political communication within limits relatively less threatening to the established order.

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