• Title/Summary/Keyword: aglycone

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A Study on the Hydrolyzed Ginseng Saponin-Quaternary and its Application in Cosmetics (가수분해된 인삼사포닌 4급 암모늄엽과 화장품으로의 응용에 관한 연구)

  • 김영대;김창규;이정남;하병조
    • Journal of Ginseng Research
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    • v.13 no.2
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    • pp.189-197
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    • 1989
  • A new quaternary ammonium compound, hydrolyzed ginseng-saponin quaternary (HGSQ), from Korean ginseng saponin and 2,3-epoxypropyltrimethylammonium chloride has been developed as a conditioning agent in cosmetics. This structure has a hydrophobic group from the aglycone of ginseng saponin which is biologically active and considered to be the most important component of the Korean ginseng. Its properties : surface tension, critical micelle concentration (CMC), eye irritation, sorption onto hair, force reduction(%) and moisture retention effect were studied. Its cationic character allows the molecule to be more substantive than ginseng saponin. HGSQ had good physical properties and was safe. enough as a cosmetic raw material. Also half-head tests of HGSQ-containing shampoo were carried out to compare the conditioning effects in shampoos. HGSQ was an excellent conditioning agent in shampoo..

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Studies on the anti-inflammatory glycosides of panax ginseng

  • Han, Byung-Hoon;Han, Yong-Nam;Woo, Lin-Keun
    • YAKHAK HOEJI
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    • v.16 no.3
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    • pp.129-136
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    • 1972
  • Two anti-infalmmatory glycosides, Panax saponin A, $C_{47}H_{72}O_{14}$ center dot $2H_{2}O$, m.p. $208-10^{\circ}$ and C, m.p. $196-202^{\circ}$, were isolated from the methanol extract of Panax ginseng. The anti-inflammatory activity of Panax saponin A was found to have delayed and prolonged characteristics. The partial structure of Panax saponin A was established to be ${\beta}{\betha}$'20S-protopanaxatriol-diglucoside. One of glucose residues was bound to the 20S-hydroxyl group of aglycone.

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Studies on Identification of the Anthocyanins in Raspberries (나무딸기 Anthocyanin에 관한 연구)

  • Joo, Kwang Jee;Park, Jung Mi
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.12 no.1
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    • pp.31-36
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    • 1983
  • The anthocyanins isolated from raspberries, were studied by column chromatography on polyvinylpyrroldone, paper chromatography, total hydrolysis, partial hydrolysis, color classification and spectroscophy. Four individual pigments were identified as cyanidin 3 digalactoside with caffeic acid, cyanidin 3 diglucoside with caffeic acid, cyanidin-3, 5-diglucoside with caffeic acid and cyanidin-3-monoglucoside with caffeic acid, respectively.

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Determination of Phenolic acids and Flavonol Aglycone Contents in Orostachys japonicus A. Berger Grown under Various Cultivation Conditions

  • Jang, Sang-Hun;Lee, Sang-Gyeong;Kang, Jin-Ho;Park, Jong-Cheol;Shin, Sung-Chul
    • Korean Journal of Medicinal Crop Science
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    • v.14 no.5
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    • pp.311-316
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    • 2006
  • The content of four phonolic acids 1-4, and two flavonol aglycones 14 and 15 from Orostachysjaponicus A. Berger grown under night-break and day-length controlled experiments was estimated and compared with those in wild plants. The amount of the phenolic acids 1-4 and the flavonol aglycones 14 and 15 increased with increasing light irradiation under both the night-break and day-length control conditions. It was disclosed that the cultivation conditions such as the night-break and the day-length control were not adversely affect the production of phenolic acids and flavonols in Orostachys japonicus A. Berger extracts.

Purification of Isoflavone from Soybean Hypocotyl Using Different Solvents

  • Park, Yeon-Bae;Kim, Min-Jung;Lee, Yoon-Bak;Sohn, Heon-Soo;Lee, Ok-Hee;Kim, Kang-Sung
    • Korean Journal of Environmental Biology
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    • v.21 no.3
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    • pp.245-250
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    • 2003
  • Composition of isoflavone in cotyledon and hypocotyl of soybean were detected using HPLC. Optimum conditions for extracting isoflavone from hypocotyl were studied as well. Contents of isoflavone in soybean cotyledon and hypocotyl were 482.5 mg 100 $g^{-1}$ and 3453.3 mg 100 100 $g^{-1}$, respectively. Hypocotyl contained 7~8 times move isoflavone than corresponding cotyledon of the soybean. Malonyl glycoside accounted for move than 70% of the total isoflavone, followed by glycoside, acetyl glycoside, and aglycone. Aqueous ethanol of 60~80% was the most suitable solvent for extracting isoflavone from the hypocotyl. Optimum temperature and time was $90^{\circ}C$, 1hr. Acetic acid, NaCl, and NaOH added to 80% ethanol suppressed extraction yield of the phytochemieal.

서목태의 식물성 에스트로겐과 프럭토즈폴리머 레반의 보충에 의한 폐경 후 여성의 골질환 개선 효과

  • 강순아;김승현;장기효;장병일;임융호
    • Proceedings of the KSCN Conference
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    • 2004.05a
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    • pp.436-437
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    • 2004
  • 폐경기성 골다공증의 치료 방법인 에스트로겐 투여에 의한 위험성을 보완하기 위해 한약재 및 식품 등 천연물의 활성성분을 이용한 대체 요법에 대한 연구가 진행되면서, 이소플라본(isoflavone)계 식물성 에스트로겐을 함유한 기능성식품의 개발이 진행되고 있다. 특히 콩과식물 중 isoflavone 함량뿐 아니라 배당체와 결합되지 않은 aglycone 함량이 높은 서목태(쥐눈이콩; 약콩)와 무기질 홉수 중진 효과를 지닌 프럭토즈폴리머(levan; beta-2,6 linked fructose polymer, ∼6,000,000 Da)를 폐경 후 여성들에게 공급하여 골형성 지표와 골흡수 지표의 변화, 혈중 칼슘 농도, 골대사를 살펴보고 골밀도의 변화를 살펴봄으로써 골다공증 예방제로서의 기능성물질의 효능을 살펴보고 신물질의 개발에 기여하고자 하였다.(중략)

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Antioxidant Activity of Flavonoids and Their Glucosides from Sonchus oleraceus L.

  • Yin, Jie;Si, Chuan-Ling;Wang, Myeong-Hyeon
    • Journal of Applied Biological Chemistry
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    • v.51 no.2
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    • pp.57-60
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    • 2008
  • Eight compounds, including 2 flavones, luteolin (1) and apigenin (2), 2 flavonols, kaempferol (3) and quercetin (4), and 4 flavonoid glucosides, luteolin-7-O-${\beta}$-D-glucoside (5), apigetrin (6), astragalin (7), and isoquercitrin (8), isolated from the whole herb of Sonchus oleraceus L. were analyzed on the basis of chemical and spectroscopic evidence. This was the first time to report compounds 3, 4, 6, 7 and 8 from the Sonchus oleraceus L. The antioxidant activities of the isolated flavonoids and their glucoside derivatives were evaluated by DPPH free radical-scavenging assay, showing that compounds 1, 3, 4 and 8 exhibited stronger antioxidant activities compared with ${\alpha}$, tocopherol and curcumin. Flavonoids containing more hydroxyl groups exhibited better antioxidant activities. The antioxidant activity of flavonols was superior to their corresponding flavones, and that of aglycone are more potent than their glucoside derivatives.

Structure elucidation of 11-epiterpestacin glycoside (11-ETG) isolated from Bipolaris sorokiniana NSDR-011

  • Lim, Chi-Hwan;Nihashi, Youichirou
    • Journal of Applied Biological Chemistry
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    • v.61 no.1
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    • pp.79-82
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    • 2018
  • An ${\alpha}-{\text\tiny{D}}-glucoside$ of sesterterpene, 11-epiterpestacin, was isolated from the culture of a filamentous fungus Bipolaris sorokiniana NSDR-011. The structure was elucidated by chemical studies and spectroscopic methods including NMR and ESI-MS. 11-ETG (1) named arbitrarily did not inhibit the root growth of Italian ryegrass seedlings even at the level of 200 ppm, while its aglycone 11-ET (2) completely inhibited root growth at level of 100 ppm.

Effect of Triterpenoidal Glycosides of Dammarane Series and Their Aglycones on Phase Transitions of Dipalmitoylphosphatidylcholine (DPPC의 상전이에 미치는 Dammarane Series의 Triterpenoidal Glycoside와 그 Aglycone의 영향)

  • Kim, Yu.A.;Park, Kyeong-Mee;Park, Hwa-Jin
    • Journal of Ginseng Research
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    • v.20 no.1
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    • pp.23-29
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    • 1996
  • The effect of ginseng glycosides and their aglycones on the thermodynamic characteristics of membranes from dipalmitoylphosphatidylcholine (DPPC) was investigated. Total saponins (TS) from Korean red ginseng, Panax ginseng C.A. Meyer, interacted with the Eel Phase of lipid in the Polar region and did not penetrate the deeper glycerol backbone of lipid molecule. From the all investigated components of TS (aglycons and ginsenosides), only 20-(S)-panaxadiol (PD) had an effect similar to TS. High concentration of TS penetrated in hydrophobic Cl-C8 region. The presence of cholesterol did not influence the interaction of TS with DPPC. An elimination of transition, however, took place at 10~100 $\mu\textrm{g}$/ml of TS. DPPC had a low ability to interact with cholesterol (CHL) as compared with other lecithins except ethanolamine. From our results, only TS and PD, at high concentrations (100 mol%), influenced the phase transition of mixture of DPPC:CHL.

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Species Differences of Dammarane Aglycones of Ginsengs (한국산(韓國産) 및 외국산(外國産) 인삼(人蔘)의 성분(成分) 비교(比較))

  • Woo, Lin-Keun;Han, Byung-Hoon;Park, Dae-Sung;Lah, Woon-Lyong
    • Korean Journal of Pharmacognosy
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    • v.4 no.4
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    • pp.181-184
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    • 1973
  • In the light of quality comparison the ratio of panaxadiol and panaxatriol contents was assayed in the extract of various ginseng products, whose origin of production and species of the original plants are different. Aglycone compositions of other ginsengs were not comparable with Korean ginseng in their ratio of panaxadiol and panaxatriol contents of dammarane glycosides.

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