• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제45권1호
• /
• pp.34-42
• /
• 2019

Objectives: Various bone graft substitute materials are used to enhance bone regeneration in the maxillofacial skeleton. In the recent past, synthetic graft materials have been produced using various synthetic and natural calcium precursors. Very recently, eggshell-derived hydroxyapatite (EHA) has been evaluated as a synthetic bone graft substitute. To assess bone regeneration using EHA in cystic and/or apicectomy defects of the jaws through clinical and radiographic evaluations. Materials and Methods: A total of 20 patients were enrolled in the study protocol (CTRI/2014/12/005340) and were followed up at 4, 8, 12, and 24 weeks to assess the amount of osseous fill through digital radiographs/cone-beam computed tomography along with clinical parameters and complications. Wilcoxon matched pairs test, means, percentages and standard deviations were used for the statistical analysis. Results: The sizes of the lesions in the study ranged from 1 to 4 cm and involved one to four teeth. The study showed significant changes in the formation of bone, the merging of material and the surgical site margins from the first week to the first month in all patients (age range, 15-50 years) irrespective of the size of the lesions and the number of teeth involved. Bone formation was statistically significant from the fourth to the eighth week, and the trabecular pattern was observed by the end of 12 weeks with uneventful wound healing. Conclusion: EHA showed enhancement of bone regeneration, and healing was complete by the end of 12 weeks with a trabecular pattern in all patients irrespective of the size of the lesion involved. The study showed enhancement of bone regeneration in the early bone formative stage within 12 weeks after grafting. EHA is cost effective and production is environment friendly with no disease transfer risks. Thus, natural bioceramics will play an important role in the reduction of costs involved in grafting and reconstruction.

• 한국산학기술학회논문지
• /
• 제20권1호
• /
• pp.64-74
• /
• 2019

본 연구는 노인의 자살생각에 중요한 영향을 미치는 것으로 밝혀진 지각된 짐스러움과 절망감을 감소시킬 변인으로 사회적 지지를 제안하고, 사회적 지지가 지각된 짐스러움과 절망감을 매개로 노인의 자살생각에 미치는 부적 영향을 확인하기 위해 수행되었다. 연구결과, 사회적 지지의 하위차원 중 가족지지는 노인의 지각된 짐스러움을 줄여줌으로써 자살생각을 감소시킬 뿐 아니라, 감소된 짐스러움이 절망감을 감소시켜 노인의 자살생각을 줄여주는 것으로 나타났다. 친구지지는 노인의 지각된 짐스러움 및 절망감을 줄여줌으로써 자살생각을 줄여줄 뿐 아니라, 감소된 짐스러움이 절망감을 낮춤으로써 노인의 자살생각을 줄여주고 있었다. 지역사회지지는 노인의 지각된 짐스러움에 영향을 미치지는 못했으나 노인이 느끼는 절망감을 줄여줌으로써 자살생각을 줄여주는 것으로 나타났다. 한편, 사회적 지지의 하위요인들(가족, 친구, 지역사회)은 자살생각에 대해 직접적인 효과를 보여주기보다, 다른 부정적인 요인을 감소시킴으로써 자살생각에 대한 간접적인 효과를 보여주었다. 이상의 결과에 근거하여, 고령화 사회와 핵가족화 사회에서 자칫 소원해 질 수 있는 가족관계를 개선하기 위한 노력의 필요성과 노인의 대인관계 및 사회적 네트워크 형성에 대한 지원, 그리고 지역사회 지원정책의 이용을 장려하는 적극적인 홍보 노력이 병행될 필요가 있음을 제안하였다.

• Psychiatry investigation
• /
• 제15권12호
• /
• pp.1162-1167
• /
• 2018

Objective Motor, perceptual, and cognitive functions are known to affect driving competence. Subcortical ischemic changes on brain magnetic resonance imaging (MRI) can reflect reduction in cognitive and motor performance. However, few studies have reported the relationship between subcortical ischemic changes and driving competence of the elderly. Thus, the objective of this study was to investigate the association between subcortical ischemic changes on MRI and driving abilities of the elderly. Methods Participants (n=540) were drawn from a nationwide, multicenter, hospital-based, longitudinal cohort. Each participant underwent MRI scan and interview for driving capacity categorized into 'now driving' and 'driving cessation (driven before, not driving now)'. Participants were divided into three groups (mild, n=389; moderate, n=116; and severe, n=35) depending on the degree of white matter hyperintensity (WMH) on MRI at baseline. Driving status was evaluated at follow-up. Statistical analyses were conducted using ${\chi}^2$ test, analysis of variance (ANOVA), structured equation model (SEM), and generalized estimating equation (GEE). Results In SEM, greater baseline degree of WMH was directly associated with driving cessation regardless of cognitive or motor dysfunction (${\beta}=-0.110$, p<0.001). In GEE models after controlling for age, sex, education, cognitive, and motor dysfunction, more severe change in the degree of WMH was associated with faster change from 'now driving' state to 'driving cessation' state over time in the elderly (${\beta}=-0.508$, p<0.001). Conclusion In both cross-sectional and longitudinal results, the degree of subcortical ischemic change on MRI might predict driving cessation in the elderly.

• 대한족부족관절학회지
• /
• 제22권3호
• /
• pp.95-99
• /
• 2018

Purpose: The purpose of this study was to evaluate the radiologic outcomes of distal fibular fractures and to analyze the risk factors associated with nonunion. Materials and Methods: Between January 2009 and March 2016, 13 patients who had final nonunion with ankle fracture were included. In the control group, 370 patients who had undergone bony union and removed metal implants were included. All patients underwent the same surgical procedure and had the same treatment method, ultimately achieving satisfactory open reduction results with less than 2 mm fracture gap. Surgical treatment of fracture was considered to have the same effect on nonunion, and factors that might be associated with nonunion were evaluated. SPSS ver. 13.0 (SPSS Inc., USA) was used for all statistical analyses. Pearson's chi-square test and multi-variate regression analysis were performed to determine the factors affecting nonunion of distal fibular fracture. A p-value less than 0.05 was considered statistically significant, and relative risk was assessed. Results: The mean age of 13 patients was 46.9 years (range, 16~57 years); there were 8 men and 5 women. Among the 13 patients with nonunion, atrophic was the most common (12 cases). The association between the injury mechanism and the Lauge-Hansen classification and diabetes mellitus was not statistically significant. Distal fibular fractures with tibia shaft fracture (p=0.015) and Danis-Weber type C fracture (p=0.023), open fracture (p=0.011), and smoking (p=0.023) were significantly associated with nonunion. Conclusion: In this study, the combined injury of the ipsilateral tibia shaft fracture, open fracture, and Danis-Weber type C fracture may increase the possibility of nonunion. Therefore, caution is advised to prevent nonunion.

• 한국건설순환자원학회논문집
• /
• 제7권1호
• /
• pp.74-81
• /
• 2019

본 연구에서는 산업부산물을 활용한 CSA와 이수석고를 광산 차수재에 적용하기 위한 기초자료를 제시하고자 CSA와 이수석고 첨가량에 따른 차수재의 특성을 검토하였으며 그 결과를 다음과 같이 나타내었다. CSA 첨가량에 따른 광산 차수재의 압축강도, 길이변화, 흡수율 측정결과 CSA30%까지는 초기재령에서의 강도증가와 더불어 수축 및 흡수율저감 효과에 긍정적인 영향을 미치는 것으로 나타났다. 그러나 CSA50%에서는 과량 사용으로 인하여 수축보상 및 공극충진보다는 과팽창으로 인한 흡수율 증가와 시멘트양 감소로 인하여 OPC와 비교하여 15% 감소하였다.

• 지역사회간호학회지
• /
• 제30권2호
• /
• pp.206-216
• /
• 2019

Purpose: This study is to investigate the low back pain, social support, impediment in daily living activities and to identify factors affecting impediment in elderly farmer' daily living activities. Methods: The participants were 128 elderly farmers who had received nerve block. Data were collected using a structured questionnaire from February to March, 2018. They were analyzed using t-test, ANOVA, pearson's correlation coefficient, and linear multiple regression. Results: The score of low back pain was $6.27{\pm}1.69$ (10 points), that of social support $2.92{\pm}0.76$ (1~5 points), and that of impediment in activity of daily living $2.01{\pm}0.82$ (0~5 points). Factors affecting impediment in activity of daily living were found to include age (p=.017), daily hours of farm work (p<.001), fear for the nerve block (p<.001), low back pain (p<.001), and social support (p<.001); the explanatory power of these variables was 58.8%. Conclusion: This study has found the controllable factors affecting impediment in activity of daily living among the rural elderly engaging in farm work include low back pain, social support, and daily farming hours. Therefore, to reduce impediment in activity of daily living among them, it is necessary to develop nursing interventions that can improve impediment in activity of daily living through reduction of daily farming hours using local resources. It is also desirable to improve their health status by reducing low back pain, and develop and apply social supports with health education programs that fit the local resources and the needs of the rural elderly.

• 대한한방소아과학회지
• /
• 제33권2호
• /
• pp.22-31
• /
• 2019

Objective This study is to learn the effects of Hataedock method using Coptidis rhizoma and Glycyrrhiza uralensis mixed extract on inflammatory response in allergic rhinitis-induced obese NC/Nga mice. Materials and Methods The mice were fed with high fat-diet to be obese, and were divided into 3 groups as follows; allergic rhinitis-induced obese mice group with Hataedock method (CGT, n=10), no treatment group (Ctrl), allergic rhinitis elicited obese mice group (ARE). To induce allergic rhinitis, NC/Nga mice of 3 weeks age were sensitized on 7, 8 and 9 weeks by ovalbumin antigen in intraperitoneal space. After 7 days of final sensitization, allergic rhinitis was initially induced in mice through nasal cavities for 5 days. After 1-week, allergic rhinitis was induced again by the same method. Histological examination was used to identify distribution of IL-4, CD40, STAT6, $Fc{\varepsilon}RI$, substance P, MMP-9, NF-${\kappa}B$ p65, iNOS and COX-2. Results Hataedock method significantly reduced IL-4, STAT6 and CD40 response (p<0.05). In CGT, the inhibition of Th2 differentiation decreased inflammatory mediators such as $Fc{\varepsilon}RI$, substance P, MMP-9, NF-${\kappa}B$ p65, iNOS and COX-2 (all p<0.05). The immunological improvement led reduction of respiratory epithelial damage and mucin secretion in goblet cell. Conclusion The results of this study show that the Hataedock method suppresses the expression of allergic rhinitis by decreasing the inflammatory mediators through the regulation of Th2 differentiation even when the inflammation reaction is increased by obesity. Therefore, Hataedock may have potential preventive measure of allergic rhinitis accompanied by obese.

• 한국생활환경학회지
• /
• 제24권5호
• /
• pp.549-561
• /
• 2017

We conducted a nationalwide questionnaire to investigate accidental experiences and injuries at flashover or flame-fire for active firefighters in the line of duty. A total of 794 firefighters participated in this survey (764 males, 27 females, and 3 respondents; $39.2{\pm}8.4yr$ in age, $173.7{\pm}5.1cm$ in height, $73.4{\pm}8.6kg$ in body mass). The results showed that high risk circumstances the most frequently experienced while firefighting in Korea was flashover followed by backdraft, rollover and flameover. At the high risk circumstances the most frequently-experienced injuries were bruise, stabs and burns. Firefighters hoped to reduce the total mass of personal protective equipment (PPE), improve the mobility of the PPE and dexterity of protective gloves, so that they could escape from the high risk circumstances as fast as possible. In particular, requirements for improvement on protective gloves were greater than those on other PPE. The present study suggested that the need for improvements on the current firefighters' PPE to cope with emergency high risk situations in terms of PPE mass reduction and mobility.

• 생물정신의학
• /
• 제27권2호
• /
• pp.64-73
• /
• 2020

Suicidality is the most serious complication of mood disorders and psychosis; effective treatment should reduce suicide rates. The Organization for Economic Cooperation and Development age-standardized suicide rate in Korea was 22.6 in 2018, much higher compared to other countries worldwide. As mental and psychiatric problems are the main reasons for suicide attempts, accounting for 31.6% in 2018, targeting such problems should be the focus of efforts to reduce suicide rates. However, the ability of current pharmacotherapeutic and psychotherapeutic interventions to reduce suicide rates is limited due to their delayed effects. Therefore, electroconvulsive therapy (ECT) has been proposed as an alternative treatment. This approach is effective for treating most mental disorders associated with high suicide rates, including severe depression, bipolar disorder, and intractable psychotic disorders; ECT is also effective for Parkinson's disease, which has the highest suicide rate among all disorders in Korea. The acute, long-term, and prophylactic effects of ECT on suicidality have been reported in the literature, and treatment guidelines outside of Korea recommend that ECT be used at an early stage for rapid reduction of suicide rates, as opposed to being applied as a treatment of last resort. However, only ~0.092 of every 10000 members of the Korean general population received ECT in 2018; this is much lower than the average rate worldwide, of 2.2 per 10000. Elimination of obstacles to the use of ECT, early crisis intervention involving administration of ECT for rapid stabilization, and maintenance ECT to prevent recurrence should reduce suicide rates.

• 국제물리치료학회지
• /
• 제10권2호
• /
• pp.1803-1809
• /
• 2019

Background: Cervical mobilization has been applied mainly for the improvement of arm and neck movements and pain reduction, and little research has been done to improve the executive function. Since this kind of so-called mechanical neck pain is one of most common symptoms, there are controversial issues about this with spine alignment. Posteroanterior (PA) mobilization from the Maitland concept is a process of examination, assessment, and treatment of neuromusculoskeletal disorder by manipulative physical therapy. Objective: To examine the short-term benefits of mobilization for patients with non-specific neck pain. Design: Dual-group Pretest-Posttest Design from the Quasi-Experimental research Methods: Fourteen participants (male 8, female 6; 20's of their age) with non-specific neck pains which are distributed all the unilateral or bilateral body side were recruited. Participants were categorized to Neck Pain with Movement Coordination Impairments (NPMCI) and Neck Pain with Mobility Deficits (NPMD) groups according to the results of physical examination. Professional physical therapist who has over 15-years-of clinical experience applicated manipulative therapy for the neck pain, an occupational therapist only conducted evaluations; K-NDI (Korean version of the Neck Disability Index), VAS (Visual Analog Scale), BDS-K (Korean version of Behavioral Dyscontrol Scale) for decreasing possible adverse effects; there were no person who reported other symptoms followed 4 weeks from the trial. Results: In the NPMCI group, data analysis indicated statistical differences between the PA mobilization interventions in NDI and BDS-K; even though, pain was reduced in VAS, this is not a significantly differ. In the NPMD group, data analysis represented statistical differences between the PA mobilization interventions in NDI, VAS and BDS-K; the scores were represented to be increased or the pain got relief. Conclusions: PA mobilization techniques according to Maitland concept have beneficial effects in patients with neck pain and other clinical positive effects which included neck disability, pain itself and motor function of upper extremity.