• Biomedical Science Letters
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• v.13 no.3
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• pp.183-187
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• 2007

Monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) playa key role in development of atherosclerosis. To take into account the atherogenic properties of MCP-1 and IL-8 and its influence on insulin resistance, we examined circulating levels of MCP-1 and IL-8 in adults. We recruited 292 subjects (84 males and 208 females) aged between 29 and 79 years. MCP-1 and IL-8 levels were measured by enzyme-linked immunosorbent assay. Age, total cholesterol, HDL-cholesterol, and LDL-cholesterol levels were significantly higher in female subjects (P<0.01, respectively), but diastolic blood pressure (BP) was significantly lower in female subjects compared to male subjects. MCP-1 and IL-8 levels were tended to increase with age, the highest in their seventies. MCP-1 (P=0.05) and IL-8 (P<0.01) levels were higher in males than in females. MCP-1 was positively correlated with age (r=0.17, P<0.05), IL-8 (r=0.26, P<0.01), fasting insulin (r=0.30, P<0.01), and HOMA-IR (r=0.29, P<0.01). In linear regression analysis, age was found to be independent factor associated with MCP-1 adjusted by age, BMI, fasting glucose, triglyceride, and systolic BP. In conclusion, age was found to be independent factor associated with MCP-1. It is possible that an increase of MCP-1 in adults with age may be risk to atherosclerosis and diabetic properties.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.17 no.3
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• pp.155-161
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• 2014

Purpose: Constipation is a common pediatric problem worldwide. This study aims to describe the clinical characteristics of pediatric constipation in south Jordan according to gender and age group. Methods: All patients with constipation managed at our pediatric gastroenterology service between September 2009 and December 2012 were included. Hospital charts were reviewed. Demographic data, clinical characteristics, and final diagnosis were recorded. Data were analyzed according to gender and the following age groups: infants, pre-school, school age, and adolescents. Results: During the study period, 126 patients were enrolled. The number (percentage) of patients according to age were the following infants: 43 (34.1%), pre-school: 55 (43.7%), school age: 25 (19.8%), and adolescents: 3 (2.4%). Males made up 54.8% of the study population. There were no statistical gender differences in any age group. The most common symptom in all age groups was dry, hard stool. Infrequent defecation was found in almost one-half of the patients. Fecal incontinence was more common in school-aged children compared to pre-school-aged children and adolescents. Abdominal pain was seen in almost 40% of the constipated children. Abdominal pain was more prevalent in girls and older children. Fecal mass in the rectum was the most common physical finding, with constipated boys exhibiting higher rates. Functional constipation was the most common etiology. Conclusion: Clinical characteristics of constipation in children vary according to age group and gender. Older children had less frequent bowel motions, a longer duration of symptoms, and a higher prevalence of long-standing constipation compilations (fecal incontinence and abdominal pain).

• Journal of Animal Environmental Science
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• v.6 no.2
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• pp.97-104
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• 2000

This study was carried out to determine the effects of different weaning age on feeding performance and behaviour of piglets. Sixty crossbred(YLxD) litters of piglets were randomly alloted to be 15 pens with 4 piglets per pen and 5 pens per treatment by weaned at 14, 21, and 28 days. Pens were video-taped for 24 hours immediately at 7 weeks and 8 weeks of age. The piglets weaned at 14 and 21 days were significantly (P<0.05) much intake than piglets weaning at 28 days. The piglets weaning at 14 days were significantly lighter than piglets weaning at 14 and 21 days fro m2 weeks to 8 weeks age. However, feed conversion ration was significantly(P<0.05) improved according to late weaning days. Times spent engaged in Feeding, lying and walking were similar in piglets across weaning age. They also showed similar occurrence of drinking and agonistic behaviour at 7 weeks and 8 weeks of age. Piglets weaned at 14 days exhibited more belly-nosing behaviour at 7 weeks of age, but similar in piglets at 8 weeks of age across weaning age. We concluded that piglets performance influenced by weaning day, however time spent for feeding, lying and walking behaviour were no significance. Drinking, Agonistic and belly-nosing were not significantly different by weaning age.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1995.04a
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• pp.90-90
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• 1995

The Influence of age on the endothelial modulation of angiotensin II (AII)-induced contractile response was investigated in isolated aortic rings of rats ranging in age from 0.7 to 20 months. Hemoglobin and L-NAME were used to examine whether age-related changes in the EDRF-releasing system were involved in endothelial modulation of All-induced contraction in rat aorta. In all five age groups (0.7, 1.5, 3, 6, 20 months), hemoglobin (10 ${\mu}$M) significantly enhanced All-induced contractile response only in aorta with endothelium intact. L-NAME (10 ${\mu}$M) Produced a significant enhancement in All responses in endothelium-intact aortas from rats aged 0.7 and 1.5 months, but it had no effect in aortas from older rats aged 6 and 20 months. Indomethacin (10 ${\mu}$M) did not affect All-induced contractile responses in both endothelium intact and removed aortas from rats at the age of 0.7 to 20 months. Hemoglobin (10 ${\mu}$M) abolished acetylcholine-induced relaxation response in aortas from young and old rats. L-NAME completely abolished the relaxation in aortas from young (0.7 and 1.5 months), but incompletely in aortas from older (6 and 20 months) rats. The sensitivity of endothelium-dependent relaxation to A23187 increased with age between ages of 0.7 and 6 months, with no further increase noted up to 20 months of age. These results suggest that endothelial modulation of AII-induced contraction in rat aorta might involve age-related alteration in EDRF-releasing system, probably via post-receptor mechanism.

• Journal of the Korean Home Economics Association
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• v.34 no.4
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• pp.49-62
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• 1996

This paper is to examine the development of Korean young children's judgement on moral and conventional rules. The subjects are 120 children, 30 each at four age levels; age 3(2.8-3.5), age 4(3.7-4.4), age 5(4.8-5.5), and age 6(5.7-6.5) in a day care center in Taegu. Results are summarized as follows: 1. In terms of nonpermissibility, there was a significant difference in regard to the moral and the conventional rule transgression between the group of age 3 years and three groups of ages 4, 5, and 6. 2. In terms of seriousness, there was a significant difference according to domain. Three groups ages 4, 5 and 6 years evaluate moral transgressions to be more serious than conventional transgressions. 3. In terms of rule contingency and generalizability, there was a significant difference in regard to the moral and conventional transgression between the group of age 3 years and three groups of ages 4, 5 and 6. 4. In terms of punishment, there was significant difference according to domain. Three groups of age 4, 5, and 6 years evaluate moral transgressions to be more punishable than conventional transgressions. 5. Children of age 5 with institutional experience do not make a distinction between moral and conventional rules on punishment criterion.

• Archives of Pharmacal Research
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• v.19 no.6
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• pp.462-468
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• 1996

The present study was undertaken to investigate the effects of age on angiotensin II (AII) response and antagonistic activity of losartan using aortic rings and liver homogenates from rats ranging in age from 0.7 to 20 months. Whether the endothelium was present or not, the maximum contractile response to AII decreased with age. Removal of the endothelium enhanced AII-induced maximum contraction and these endothelial effects seemed to be due to endothelium-derived relaxing factor (EDRF) in all ages. Equilibrium binding studies demonstrated an age-related decrease in maximum binding $(B_{max})$ with little change in binding affinity $(K_d)$. In rat aorta, the extent of losartan-induced parallel shifts $(K_B)$ in AII concentration-response curves was not significantly different between ages. In addition, $IC_{50}$ value of losartan in competition binding was not changed with age in rat liver homogenates. These results suggest that the potency of losartan is not altered with age in rat aorta and liver, although AII-induced contractile response and the maximum AII binding decreased significantly with age.

• Korean Journal of Clinical Laboratory Science
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• v.42 no.3
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• pp.155-160
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• 2010

Transcranial Doppler ultrasonography (TCD) allows measurement of blood flow velocity to be made from the basal intracerebral vessels. Blood flow velocity in TCD is highly affected not only by blood vessel diameter, blood flow volume, blood viscosity, but also age and sex. Therefore, the study is focused on the correlation between TCD measurement index and sex/age. Subjects were 214 (male 147, famale 67) who had TCD for headache and stroke evaluations at Dongguk University Ilsan Hospital neurology department from December 2009 to April 2010. Sex did not show significant differences with mean flow velocity (MFV), peak systolic flow velocity (PSFV), end diastolic flow velocity (EDFV), pulsatility index (PI) and resistance index (RI) in middle cerebral artery (MCA). Although age also did not show significant differences with MFV and PSFV, EDFV has statistically decreased with age, and PI and RI has statistically increased with age. In addition, age showed significant correlation with MFV, EDFV, PI and RI, but not with PSFV. Therefore, TCD is definitely correlated with age and sex, so that those influencial factors must be considered when being tested.

• Journal of Families and Better Life
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• v.20 no.6
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• pp.141-149
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• 2002

In order to promote well-being during old age, it is important to start preparing early on for the later life. Based on this thesis, this study examined attitudes of the middle-aged women residing in rural towns on their preparation for old age as well as related variables. For this purpose, survey data from 200 individuals were analyzed using a SAS program. The overall degree of preparation for old age was quantified as about 67 points out of a 100 possible points. The variables that affected the level of preparedness include attitude toward using a paid nursing home ($\beta$=.23), type of agricultural work they engage in ($\beta$=-.21), who do you think is a supporter during your old age($\beta$=.20)］, type of decision-making in the household ($\beta$=.17). The explanatory power of such variables as standards of living ($\beta$=.18), family type ($\beta$=-.18), recognition of the entrance of old age ($\beta$=.17), and preparation behavior for old age ($\beta$=.15) were partially proved in three sub-areas (economical, emotional, and leisure areas) of preparation. The groundwork of this study could be used as basic materials to develop an educational program to improve the attitudes toward preparation for old age.

• Journal of the Korean Society of Clothing and Textiles
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• v.15 no.2 s.38
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• pp.103-113
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• 1991

The purpose of this study was to investigate the effect of physical type and age on preference for line in women's clothing design. Line preference in clothing design was concerned with varying in length, direction, division, and shape. All of the preference measures were devised specifically for this study. Furthermore, items on height and weight for physical type as well as age of the subjects were included in the questionnaire. Data were obtained by means of structured interviews and self-administered questionnaires from 588 women ($20\~60$ years of age) in Seoul. Analysis was by One·way ANOVA, Chi-square ($X^{2}$), and Scheffe test. It was found that 4 categories of line preference were affected by both body type and height. An age effect was found on 3 categories of design lines; however, preference for 2 categories of design lines in clothing styles were unaffected by either physical type or age. It was concluded that body type, height, and age are powerful predictive variables for line preference in clothing design. Generally, there was some similarities in preference for lines among slim body types, tall figures, and younger age group as well as heavy body types, short figures, and older age group.

• Safety and Health at Work
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• v.8 no.4
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• pp.393-397
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• 2017

Background: It has been suggested that engaging technology can empower individuals to be more proactive about their health and reduce their health risks. The aim of the present intervention was to study the effects of technology-aided testing and feedback on physical activity and biological age of employees in a middle-sized enterprise. Methods: In all, 121 employees (mean age $42{\pm}10$ years) participated in the 12-month three-arm cluster randomized trial. The fitness measurement process (Body Age) determined the participants' biological age in years. Physical activity was measured with the International Physical Activity Questionnaire Short Form. Results: Physical activity did not change during the intervention. Biological age (better fitness) improved in all groups statistically significantly (p < 0.001), but with no interaction effects. The mean changes (years) in the groups were -2.20 for the controls, e2.83 for the group receiving their biological age and feedback, and -2.31 for the group receiving their biological age, feedback, and a training computer. Conclusion: Technology-aided testing with feedback does not seem to change the amount of physical activity but may enhance physical fitness measured by biological age.