• YAKHAK HOEJI
• /
• v.55 no.5
• /
• pp.391-397
• /
• 2011

KML001 reduced the proliferation of HCT116 cells in a concentration- and time-dependent manner without change of cell viability. Beclin-1 expression was significantly attenuated by KML001 (P<0.05), but no significant changes were observed in KML001-treated cells. The number of cells in G1 phase was increased 48 hr after KML001 treatment. Furthermore, a dramatic reduction in the frequency of beating and the number of embryoid bodies of the cells was noted after treatment. Taken together, KML001 suppresses the proliferation of HCT116 cells, which might be due to G1 phase arrest.

• Restorative Dentistry and Endodontics
• /
• v.47 no.3
• /
• pp.30.1-30.15
• /
• 2022

Objectives: This study aimed to evaluate the effectiveness of final irrigation with cold saline solution after endodontic treatment compared with saline solution at room temperature against postoperative pain following endodontic treatment. Materials and Methods: A broad search was performed in the PubMed, Web of Science, Scopus, Cochrane Library, Virtual Health Library (LILACS), and Grey Literature databases. Two independent reviewers performed data extraction, risk of bias using the Cochrane methodology, and certainty of evidence using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. Results: Eight studies were included in qualitative synthesis. Intracanal cryotherapy favored the reduction of postoperative pain in the systematic review. Four studies were included in meta-analyses. The meta-analysis showed that intracanal cryotherapy reduced postoperative pain in teeth with symptomatic apical periodontitis (SAP) at 24 hours. There was no association between intracanal cryotherapy and control (room temperature) groups in teeth with normal periapical tissue with respect to postoperative pain at 24 hours and 48 hours. Conclusions: Intracanal cryotherapy was effective in reducing postoperative pain after endodontic treatment in teeth with SAP.

• Journal of the Korean Dietetic Association
• /
• v.30 no.2
• /
• pp.140-151
• /
• 2024

This study evaluated the effectiveness of an obesity program developed to solve 'obesity', which was selected as the top priority for urgent improvement among the dietary problems of elementary school students in Busan. The program aimed to practice four health rules every day (sleep early, eat two vegetables with each meal, reduce sugary snacks, and exercise for 30 minutes every day). The participants were trained to practice the four rules online in real time every day for three weeks, and their performance in nutrition education tasks was monitored using Padlet. The anthropometric measurements showed no change in the overall average weight before and after participating in the program, but all students grew in height (z=-6.978, P<0.001), and the number of obese students decreased significantly (z=-3.317, P<0.001). This obesity program was effective in improving height growth and obesity in elementary school students. In terms of dietary changes, after participating in the program, the frequency of vegetable consumption increased significantly (z=-4.849, P<0.001), the frequency of sweet snack consumption decreased significantly (z=-4.298, P<0.001), and the bedtime improved (z=-1.000). Therefore, the non-face-to-face, self-directed obesity program developed in this study is expected to reduce the workload of nutrition teachers carrying a heavy workload such as meal service and nutrition classes, and can be used as an efficient nutrition counseling program.

• Physical Therapy Korea
• /
• v.17 no.4
• /
• pp.61-68
• /
• 2010

The purpose of this study was to investigate the effects of a workplace-based work-conditioning program (WCP) on the management of work-related musculoskeletal disorders (WRMDs) in an automobile-parts manufacturing company. In total, 1,110 subjects with WRMDs participated in workplace-based WCP emphasizing function-centered management and ergonomics. We investigated the incidence of WRMDs variables (number of persons diagnosed with industrial accident-related WHMDs, number of cases of WRMD) and financial benefits (cost of workers' compensation insurance and lost work days related to WRMDs) per year before and after WCP. Additionally, we compared self-reported pain intensity and functional disability in subjects with musculoskeletal pain before and after the WCP. Pain intensity was measured using a visual analog scale (VAS), and functional disability was measured by the neck disability index (NDI) and the Oswestry disability Index (ODI). The number of person diagnosed with industrial accident-related WRMDs, the number of cases of WRMD, the cost of workers' compensation insurance and lost work days related to WRMDs per year decreased by 51%, 37%, 34%, and 47%, respectively, and VAS, NDI, and ODI scores decreased significantly after implementation of WCP (p<.05). Thus, the results of the present study suggest that function-centered, workplace-based WCP was effective in managing WRMDs at an automobile-parts manufacturing company.

• Journal of the Korean Data and Information Science Society
• /
• v.22 no.5
• /
• pp.867-875
• /
• 2011

In this paper, we investigate the true state of administration about after-school programs of disability schools, study the requests of the children' protectors, and support the basic materials to find the systematic and concrete after-school programs of disability schools.

• Journal of the Korean Society of Earth Science Education
• /
• v.4 no.2
• /
• pp.102-107
• /
• 2011

In this study, elementary school science program, this category did not affect any troubleshooting analyzed. Thinking Science Program to buy for them in group activities by using one of the elements of a program of treatment and cognitive level effects were two kinds of research questions. 102, 5th grade four classes were involved, these two classes of the experimental group and the remaining two classes were divided into a control group. Pre-test between the two groups is compared to the level and classification problem-solving skills but the skills did not show a statistically significant difference. Thinking Science activity after application of classification and posttest the experimental group than in the control group problem solving abilities of students classified at the level of statistical significance was higher. Thinking Science program is a treatment effect for each level of analysis, tests, regardless of cognitive level was more effective. Through theses findings, Thinking Science activities 5th grade category classification problem-solving skills of students found to be effective in improving and these types of programs actively introduced in the field suggests that we need to see.

• Journal of Korean Academy of Nursing Administration
• /
• v.7 no.2
• /
• pp.253-263
• /
• 2001

Purpose : To determine the change of effects of nursing ethics education on the nurses' ethical decision making with the time relapse of one month, three months and six months. Method : Thirteen participated in free discussion group, and fourteen participated in expert-guided discussion group for five weeks. Two weeks before the education, DIT and JAND were assessed, and JAND was assessed again on month, three months and six months after the five weeks' education program. Results : 1) Average realistic scores of JAND did not showed significant differences as times went by. However, scores were highest at three months after the education in general. 2) In both of free discussion and expert-guided discussion group, JAND score increased after the education, and highest at three months in general. 3) Low level moral development group showed highest scores at one month after the education, and declined at three month. However, in middle and high level of moral development groups, scores were higher at three months than at one month after the education. Scores were declined again at six months after the education. Conclusion : Effects of moral education program were highest at three months after the education, and were lessened as times went by. Especially for the low moral development group, effect was not continued more than one month. Therefore, more persistent, periodic education program was required until the ability of ethical decision making is settled down.

• Nutritional Sciences
• /
• v.5 no.4
• /
• pp.221-227
• /
• 2002

The objective of this study was to examine the effects of a weight loss program on the degree of obesity and levels of resting energy expenditure (REE) in overweight subjects according to their mitochondrial uncoupling protein 2 (UCP 2) genotype. Twenty-three subjects with a body mass index (BMI) greater than 27 were recruited from the Obesity Clinic of the Kyung-Hee University Hospital during the period of December 2000 - August 2001. The subjects were genotyped for the exon 8 allele; 15 subjects were found to be of del/del genotype, 8 were del/ins, and none were of ins/ins genotype. No significant association was found between the different UCP 2 genotypes and the initial levels of weight, fat mass (FM), lean body mess (LBM), BMI, REE, and REE/LBM ratio. After 12 weeks of a weight loss program, body weight and FM were significantly decreased, while LBM, total body water (TBW), and REE were not changed, irrespective of UCP 2 genotype. Initial fasting plasma levels of albumin, glucose, triglyceride, lipoprotein cholesterol, insulin, free triiodo-thyronine (T3), free fatty acid (FFA), and leptin were not different according to the UCP 2 genotype; furthermore, these blood parameters were not changed after the 12-week weight loss program. However, plasma levels of leptin decreased in both the del/del and ins/del genotypes, from 18.7 ng/ml to 13.4 ng/ml (p<.05), and from 18.1 ng/ml to 13.9 ng/ml (p＜.05), respectively, after the weight loss program. In conclusion, this study found no significant association between the del/del or del/ins UCP 2 genotypes and differing levels of REE or differing degrees of obesity, either before or after a weight loss program. This study provided evidence that a well- managed weight loss program could maintain levels of REE, which plays an important role in the maintenance of energy balance.

• Journal of dental hygiene science
• /
• v.12 no.3
• /
• pp.287-294
• /
• 2012

The aim of this study was to investigate the effect of standardized oral health care program by dental hygiene school students. Target population was 100 University students who attended standardized oral health care program by a dental hygiene school students. Present study was conducted during first and second semester in 2011 at E dental hygiene school. We analysed students' oral health related knowledge, attitude, behavior, and self-oral hygiene care ability after the program. Univariate analysis, Chi-square test and paired t-test were conducted using SAS version 9.2. University students' who attended standardized oral health care program by dental hygiene school students oral health related knowledge, attitude, behavior, and self oral-hygiene care ability were significantly improved whether they have attended oral health related lectures or not(p<.05). It is recommended provide standardized oral health care program to university students by dental hygiene school students to promote their oral health related knowledge, attitude, behavior, and self-oral hygiene care ability.

• International Journal of Advanced Culture Technology
• /
• v.10 no.1
• /
• pp.36-41
• /
• 2022

Cyberbullying and digital drama are on the rise among students. Therefore, this paper proposes an educational program that can enhance students' ability to use artificial intelligence(AI) technology and develop the power to respond to digital drama. In order to understand the effect of the proposed education program, this education was applied on a trial basis to 205 middle school students residing in South Korea. Moreover, the change of coping ability to the digital drama was observed before and after education. After applying for the educational program, the students' empathy(t=-5.506, p<0.001), peer conflict resolution(t=-3.842, p<0.01), and peer mediation(t=-4.213, p<0.001) improved, and did not significantly affect their anger control ability(t=-0.272, p>0.05). The educational program proposed in this paper uses AI to make it more attractive for students familiar with digital devices to participate in education and increase their educational concentration. This paper has its limitations as it is a study only for middle school students in South Korea. However, it is significant that the educational program proposed in this paper prevented the recently increased digital drama and led to a crucial change in coping ability.