• Advances in Traditional Medicine
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• 제9권4호
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• pp.335-338
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• 2009

Aerial parts of Sida rhombifolia Linn. (Malvaceae) were extracted successively using various solvents and screened for various parameters of antiarthritic activity such as adjuvant-induced arthritis, motor performance, and histopathological study. The ethanol and the aqueous extracts showed potent activity; further these extracts were fractionated by using column chromatography. The fraction ET1 isolated from ethanol extract showed the most potent antiarthritic activity.

• Archives of Pharmacal Research
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• 제24권5호
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• pp.427-430
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• 2001

The antioxidant activity of Lactuca scariola (Compositae) was investigated by measuring the radical scavenging effect on DPPH (1,1-diphenyl-2-picrylhydrazyl) radical. The methanolic extract of the aerial parts of Lactuca scariola showed strong radical scavenging activity. The EtOAc soluble fraction exhibited a stronger activity than the others, and was purified by silica gel and Sephadex LH-20 column chromatography. Quercetin-3-O-$\beta$-D-glucopyranoside, luteolin-7-O-$\beta$-D-glucopyranoside, luteolin, quercetin and kaempferol, together with 11$\beta$,13-dihydrolactucin were isolated from the EtOAc soluble fraction as active ingredients.

• Natural Product Sciences
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• 제15권2호
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• pp.66-70
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• 2009

Phytochemical investigation of the aerial parts of Conyza discoridis (L.) Desf. resulted in the isolation of the new sesquiterpene dilactone ester vernomenin-6-(2-hydroxymethyl)-acrylate (4) and two known sesquiterpene dilactones vernolepin (1) and vernomenin (3). Two known flavonols, 3-O-methylquercetin (2) and transilin (3-O-methylquercetin 7-O-${\beta}$-D-glucopyranoside) (5), were also identified. The structures were determined utilizing physical, chemical and spectral methods.

• 생약학회지
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• 제25권1호
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• pp.73-75
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• 1994

A flavone glycoside was isolated from the aerial parts of Cirsium nipponicum Makino in good yield and identified as pectolinarigenin $7-O-{\alpha}-{_L}-rhamnopyranosyl(1{\longrightarrow}6)-{\beta}-{_D}-glucopyranoside$, pectolinarin, on the basis of chemical and spectroscopic evidence.

• 약학회지
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• 제54권3호
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• pp.164-167
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• 2010

Column chromatographic separation of the MeOH extract from the aerial parts of Hibiscus manihot led to the isolation of four compounds. Their structures were characterized to be hentriacontane (1), palmitic acid (2), daucosterol (3) and 3-dihydrocaffeonyl-5-p-coumaroylquinic acid (4) by spectroscopic methods. The compounds (1~4) were for the first time reported from this plant. The solvent fractions were tested for their antioxidant activities by free radical scavenging and superoxide dismutase (SOD).

• 약학회지
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• 제48권1호
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• pp.65-69
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• 2004

The chromatographic separation of MeOH extract of the aerial parts of Aster glehni (Compositae) led to the isolation of three sesquiterpenes, two sterols and four terpenes. Their structures were determined to be $\beta$-amyrin acetate (1), phytol (2), alismol (3), $\alpha$-tocopheryl quinone (4), $\alpha$-spinasterol (5), 10-O-methyl alismoxide (6), alismoxide (7), and 3-O-(6'-O-palmitoyl-$\beta$-D-glucosyl)-spinasta 7,22-diene (8) by physicochemical and spectroscopic methods . These compounds (1-8) were first isolated from the Aster glehni.

• Natural Product Sciences
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• 제18권3호
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• pp.195-199
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• 2012

Nine iridoid glycoside derivatives were elucidated from the methanolic extract of the aerial parts of Galium spurium (Rubiaceae) through repeated column chromatography. Their chemical structures were characterized as 10-O-trans-p-coumaroylscandoside (1a), 10-O-cis-p-coumaroylscandoside (1b), 10-O-trans-p-coumaroyl-10-O-deacetyldaphylloside (2), 10-O-cis-p-coumaroyl-10-O-deacetyldaphylloside (3), asperulic acid methylester (4), asperuloside (5), asperulosidic acid (6), scandoside (7), and deacetyl asperulosidic acid (8) by spectroscopic analysis. This is the first report of the characterization of compounds 1a, 1b, 2, 3 and 7 from this plant.

• Natural Product Sciences
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• 제14권4호
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• pp.265-268
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• 2008

Phytochemical investigations on the aerial parts of Asplenium scolopendrium led to the isolation of four terpenoids, the structures of which were assigned as lutein (1), (6S,9S)-roseoside (2), icariside $B_2$ (3), and picrionoside A (4) using spectroscopic data.

• 한국식품저장유통학회지
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• 제16권3호
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• pp.412-418
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• 2009

우산나물의 식품학적 가치와 기능성 식품 소재로서의 개발 가능성을 검토하기 위하여 우산나물의 지상부와 뿌리에 함유된 수용성 단백질과 당, 아미노산, 무기질 그리고 폴리페놀과 플라보노이드 화합물의 함량을 측정하였다. 지상부의 수용성 단백질은 210.36 mg%였으며 뿌리는 870.42 mg%, 환원당은 지상부 848.12 mg%, 뿌리 1,420.91 mg%, 그리고 유리당은 각각 14.85 mg%와 355.00 mg%로 뿌리의 glucose 함량이 256.25 mg%로 전체 유리당의 약 70% 이상을 차지하였다. 유리아미노산은 지상부에서 1,613.10 mg%으로 glutamic acid(233.24 mg%)와 lysine(211.13 mg%)을, 뿌리에서는 3,282.96 mg%로 arginine(896.32 mg%), alanine(448.37 mg%)의 함량이 비교적 많았다. 아미노산 유도체는 지상부에서 377.83 mg%였으며, 뿌리에서는 1,126.57 mg%를 함유하였다. 무기질은 지상부와 뿌리에서 각각 3,531.53과 1,878.34 mg%으로 K가 75% 이상을 함유하였으며, Ca와 Mg의 함량도 비교적 많았다. 그리고 우산나물 지상부는 1,920.00 mg%의 폴리페놀과 843.95 mg%의 플라보노이드를 함유하며 뿌리에는 각각 487.56과 91.07 mg%를 함유하는 것으로 분석되었다. 우산나물 지상부는 뿌리보다 무기질과 폴리페놀 그리고 플라보노이드 화합물의 함량이 높았고, 뿌리는 수용성 단백질, 환원당과 유리당 그리고 아미노산의 함량이 지상부보다 높은 것으로 나타났다. 이상의 결과 우산나물의 어린순만 식용하나 뿌리에서도 다량의 생리활성 물질과 영양성분을 함유하므로 기능성 식품소재로서의 개발 가능성이 있는 것으로 사료된다.

• 한국약용작물학회지
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• 제24권6호
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• pp.437-443
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• 2016

Background: Previous phytochemical studies of whole Vernonia cinerea L. plants have identified sesquiterpene lactones, sterols, and triterpenes, which possess anticancer, antifeedant, and antimalarial activities. However, there are no reports of other types of bioactive metabolites. Therefore, the present study aimed to identify phenolic compounds with anti-inflammatory activity in the aerial parts of the plant. Methods and Results: Compounds were isolated from the aerial parts of V. cinerea using a silica and C-18 gel columns and semi-preparative HPLC instrument, and the structures of the compounds were determined using one- and two- dimension nuclear magnetic resonance spectroscopy and mass spectroscopy. The chloroform soluble extracts and isolated compounds were evaluated for their anti-inflammatory potential based on their ability to inhibit nitric oxide production and $TNF-{\alpha}$ induced $NF-{\kappa}B$ activity. Conclusions: Phytochemical study of the aerial parts of V. cinerea led to the isolation of six phenolic compounds. Compound 1 was a major metabolite, and to the best of our knowledge, compounds 2 - 6 were isolated from V.cinerea for the first time. Among the isolates, compounds 1 and 3 exhibited $TNF-{\alpha}$-induced $NF-{\kappa}B$ activity with $IC_{50}$ values of 7.5 and 11.5 M, respectively, and the inhibitory activity of phenyl propanoid compound 3 on $TNF-{\alpha}$-induced $NF-{\kappa}B$ was evaluated for the first time.