• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.18 no.2
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• pp.104-108
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• 2005

Drug eruption refers to an adverse effect which is unintentionally given rise to by dosage, injection, inhalation, suppository and ointment, etc. Maculopapular, urticarial, morbilliform, papulosquamous, pustular, and bullous morphologies may be encountered. Adverse drug reactions also can cause pruritus or dysesthesia unaccompanied by rash. We treated a patient suffered from maculopapular rash and pruritus with acupuncture, herb medication and wet dressing. After treatment we observed the improvement. Based on this study, it is considered that oriental medical treatment can be applied to the management of drug eruption.

• Biomedical Science Letters
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• v.16 no.3
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• pp.139-149
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• 2010

The present study was carried out to elucidate whether an environmental strain of Cryptococcus neoformans (environmental C. neoformans) isolated from an environmental source in a park of Busan has an acute pathophysiological effect in rats. On the second day after peritoneal inoculation of environmental C. neoformans, adverse effects occurred from the viewpoint of hematology and biochemistry. Eosinophil damages and crystal formations were found in the blood. Disturbances in cytokines production were observed in the cerebral and pulmonary tissues. Fungal budding existed in the brain, lung, liver and kidney. Tissue injury findings such as inflammation, leukocyte infiltration, bleeding, or degeneration were found in the brain, lung, liver and kidney. The present data suggest that the environmental C. neoformans can cause systematically harmful effects even for short periods of infection (two days of cryptococcal infection) and the adverse effects are summarized as immune derangements and biochemical and/or histological dysfunction and injury on major organ such as the brain, lung, liver and kidney in the immunocompetent hosts. Further studies should be focused on comparing the differences between environmental and clinical strains of C. neoformans.

• Journal of The Korean Society of Clinical Toxicology
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• v.9 no.2
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• pp.101-104
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• 2011

Nicolau syndrome is a rare adverse reaction at the site of an intramuscular injection, and is characterized by severe pain immediately after the injection and rapid development of distinct skin lesions. As this syndrome is rare, it may be overlooked at the early clinical phase and subsequently, clinical outcomes may be worse due to delay in treatment. We report on a female who developed Nicolau syndrome following intramuscular diclofenac injection, which required surgical reconstruction. Understanding the characteristics of Nicolau syndrome and careful surveillance for relevant clinical features may help physicians to more quickly diagnose and treat this condition.

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2006.06a
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• pp.67-71
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• 2006

Strong oxidizing biocides are commonly used to control biofilm formation in alkaline papermaking systems. However, paper streams contain many substances that react with or consume oxidizers (e.g., fiber and starch, Therefore, to achieve effective microbiological control, the oxidizer must be overfed to overcome the effect of these substances. When dosed in this manner, the oxidizer can cause many unwanted reactions and adverse side effects, including the consumption of costly papermaking additives increased corrosion rates, and reduced felt life. Some oxidizers also contribute to the formation of halogenated organic compounds. When used for biofilm control, strong oxidizers can cause more problems than they remedy. A patented biocide that effectively controls biofilm without the adverse side effects associated with strong oxidizing biocides is available from Hercules. $Spectrum^{(R)}$ XD3899 Ammonium Bromide Technology, which can be described as a mild oxidizer, is currently used on more than 300 machines globally and has resulted in numerous production and/or machine efficiency records since its introduction in 2001.

• 한국전산유체공학회:학술대회논문집
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• 2008.03b
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• pp.341-344
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• 2008

The complicated helical flow formed in the regenerative turbomachines is usually decomposed into a peripheral component and a circulatory component. On the basis of the momentum exchange theory, the circulatory flow plays a critical role of imparting angular momentum to the peripheral flow. Therefore, the accuracy of performance prediction is dominated by the circulatory flow modeling. Until now the circulatory flow has been accounted of a standstill flow normal to the peripheral flow. However, the circulatory path from the impeller exit to the re-entrance inlet is exposed to the adverse pressure gradient, so it would be more realistic to describe that the circulatory flow is formed on the skewed plane not perpendicular to the peripheral flow. Present study suggests new circulatory flow loss model including the effect of adverse pressure gradient and modifies the effective circulatory flow rate and circulatory pivot which were previously published.

• Journal of Korean Society for Atmospheric Environment
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• v.11 no.4
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• pp.373-375
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• 1995

In order to turn the Bag Filter to the Purse Filter, the past system that the adverse reason is removed, the input of synthetic materiality of dust and air is placed down, and the output is placed up has been improved so that any adverse effect shall not be raised. The form of filteration mechanism is changed from a cylinder from, and the dust and air is mixed to make the entry velocity and one person can velocity of the mixed materiality become lower by the use of infinity, and the reception of filteration mechanism has been made reasonably. The dust separated from the filteration mechanism is desceded down, snd the mixde materiality is ascended up. So, a cross point is formed, and a collision and a friction is occurred from its process, and at its result, dust is scattered to stick to a filter cloth, therefore, the loss of pressure shall ont be appeared by cause of the increase of dust-loading.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.10a
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• pp.871-872
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• 2013

최근 스마트폰의 급속한 보급에 따라 트위터, 페이스북과 같은 실시간 SNS(Social Network Service)가 폭발적으로 성장하고 있다. 본래 SNS는 지인과의 소통을 위한 온라인 커뮤니티로 출발했으나 지금은 새로운 커뮤니케이션으로 마케팅, 미디어, 커머스 등 다양한 영역의 플랫폼으로 진화하며, 그 파급력을 이어가고 있다. SNS, 소셜 미디어 시대를 맞이하여 소비자가 수동적 입장에서 능동적 입장으로 변경되고 있는 상황에서 블로그, 카페, 트위터 등 에서의 평가를 통한 고객 피드백 정보에 따라 서비스 제공자의 판매율이 많은 영향을 받고 있다. 따라서 효율적인 기업경영을 위해서는 SNS 등을 통한 고객의 목소리를 분석하는 작업과 그것을 기반으로 고객만족도 평가모형에 대한 연구가 필요하다. 본 논문에서는 이러한 SNS를 이용한 활용분야에 대해서 고찰해 보고 SNS가 점차 확대됨에 따라 발생할 수 있는 SNS 환경에서의 역기능은 어떤 것이 있는지 살펴보고 대응방안을 제안한다.

• Annals of Clinical Neurophysiology
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• v.17 no.2
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• pp.91-94
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• 2015

The adverse effects of systemic steroid medications are well known, whereas those of local steroid injections are unclear even to clinicians. We report two cases of localized lipoatrophy and depigmentation following local steroid injection. Although the incidence of soft tissue atrophy after local steroid injection is rare, it will increase in proportion to the frequency of the procedure. All clinicians, even those who do not perform steroid injections, should be aware of the occurrence of this cosmetically disturbing adverse effect.

• YAKHAK HOEJI
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• v.47 no.2
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• pp.104-109
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• 2003

The present paper reviews the notion and comparison of the Korea Food and Drug Administration(KFDA) general pharmacology and the International Conference on Harmonisation (ICH) safety pharmacology. General pharmacology or safety pharmacology is termed the study to determine the potential of a compound to induce adverse pharmacological effects. KFDA general pharmacology studies have been considered an important component in drug safety assessment and these were originally referred to those designed to examine effects other than the primary therapeutics effect of a drug candidate. The KFDA notified the Guideline for General Pharmacology in 1997. Safety pharmacology studies were focused on identifying adverse effects on physiological functions. In the ICH came into place S7A Safety Pharmacology Studies for Human Pharmaceuticals in 2001. A new chemical entity should be assessed for its side effects, initially in those physiological systems which are generally agreed to be the key systems that are essential for life; these "core system" include the central nervous system, cardiovascular system and respiratory system in safety pharmacology studies. These studies should be performed in compliance with Good Laboratory Practice (GLP).

• Proceedings of the KIEE Conference
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• 2004.11b
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• pp.60-62
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• 2004

Transmission line outage is influenced by several weather factors: wind, rain snow, temperature, cloud and humidity. And most power system reliability studies assume a failure rate. It can be calculated by transmission line outage data and weather data. Also weather is divided into normal weather and adverse weather by failure rate analysis. The effect of failure rate is discussed with both normal weather and adverse weather. It can be used in effective information about system operation and planing.