• Title/Summary/Keyword: advanced stage

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Single Axis Vibration Isolation System Using Series Active-passive Approach (직렬형 능-수동 제진 방법을 이용한 1축 제진 시스템)

  • Banik, Rahul;Lee, Dong-Yeon;Gweon, Dae-Gab
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2005.11a
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    • pp.176-179
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    • 2005
  • To control the vibration transmitted to the precision instruments from ground has always been of great interest among the researchers. This paper proposes a single axis vibration isolation system which can be used as a module far a table top six axis isolator for highly precise measurement and actuation system. The combined active-passive isolation principle is used for vertical vibration isolation by mounting the instrument on a passively damped isolation system made of Elastomer along with the active stage in series which consists of very stiff piezo actuator. The active stage works in combination with the passive stage for working as a very low frequency vibration attenuator. The active stage is isolated from the payload disturbance through the Passive stage and thus modularity in control is achieved. This made the control algorithm much easier as it does not need to be tuned to specific payload.

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Electromagnetic Micro x-y Stage for Probe-Based Data Storage

  • Park, Jae-joon;Park, Hongsik;Kim, Kyu-Yong;Jeon, Jong-Up
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.1 no.1
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    • pp.84-93
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    • 2001
  • An electromagnetic micro x-y stage for probe-based data storage (PDS) has been fabricated. The x-y stage consists of a silicon body inside which planar copper coils are embedded, a glass substrate bonded to the silicon body, and eight permanent magnets. The dimensions of flexures and copper coils were determined to yield $100{\;}\mu\textrm{m}$ in x and y directions under 50 mA of supplied current and to have 440 Hz of natural frequency. For the application to PDS devices, electromagnetic stage should have flat top surface for the prevention of its interference with multi-probe array, and have coils with low resistance for low power consumption. In order to satisfy these design criteria, conducting planar copper coils have been electroplated within silicon trenches which have high aspect ratio ($5{\;}\mu\textrm{m}$in width and $30{\;}\mu\textrm{m}$in depth). Silicon flexures with a height of $250{\;}\mu\textrm{m}$ were fabricated by using inductively coupled plasma reactive ion etching (ICP-RIE). The characteristics of a fabricated electromagnetic stage were measured by using laser doppler vibrometer (LDV) and dynamic signal analyzer (DSA). The DC gain was $0.16{\;}\mu\textrm{m}/mA$ and the maximum displacement was $42{\;}\mu\textrm{m}$ at a current of 180 mA. The measured natural frequency of the lowest mode was 325 Hz. Compared with the designed values, the lower natural frequency and DC gain of the fabricated device are due to the reverse-tapered ICP-RIE process and the incomplete assembly of the upper-sided permanent magnets for LDV measurements.

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Survival Outcomes of Advanced and Recurrent Cervical Cancer Patients Treated with Chemotherapy: Experience of Northern Tertiary Care Hospital in Thailand

  • Boupaijit, Kuanoon;Suprasert, Prapaporn
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1123-1127
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    • 2016
  • Chemotherapy is the primary treatment for advanced and recurrent cervical cancer. To evaluate the survival outcomes of chemotherapy and the prognostic factors in this setting, we conducted a retrospective study by reviewing the medical records of advanced and recurrent cervical cancer patients treated with systemic chemotherapy at our institute between January, 2008 and December, 2014. One hundred and seventy-three patients met the criteria with a mean age of 50.9 years. 4.1% of them were HIV positive. The most common initial stage was stage IVB (30.1%) and the most common histology was squamous cell carcinoma (68.6%). Ninety-two (53.2%) patients were previously treated with concurrent chemoradiation with 53% developing combined sites of recurrence. The median recurrence free interval was 16.7 months. Cisplatin + 5 fluorouracil (5FU) (53.2%) was the most frequent first line chemotherapy followed by carboplatin + paclitaxel (20.2%) with an objective response of 39.3%. Seventy-two patients received subsequent chemotherapy. The median overall survival of all studied patients was 13.2 months. Only a recurrence free interval of less than 12 months was an independent prognostic factor for survival outcome. In conclusion, chemotherapy treatment for advanced and recurrent cervical cancer patients showed modest efficacy with a shorter recurrence free survival less than 12 months as a significant poor prognosis factor.

Two-Stage Ring Oscillator using Phase-Look-Ahead Mehtod and Its Application to High Speed Divider-by-Two Circuit (진상 위상 기법을 이용한 2단 링 구조 발진기 및 고속 나누기 2 회로의 고찰)

  • Hwang, Jong-Tae;Woo, Sung-Hun;Hwang, Myung-Woon;Ryu, Ji-Youl;Cho, Gyu-Hyeong
    • Proceedings of the KIEE Conference
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    • 1999.07g
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    • pp.3181-3183
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    • 1999
  • A CMOS two-stage oscillator applicable to requiring in- and quadrature-phase components such as RF and data retiming applications are presented using phase-look-ahead technique. This paper clearly describes the operation principle of the presented two-stage oscillator and the principle can be also applicable to the high speed high speed divide-by-two is usually used for prescaler of the frequency synthesizer. Also, the sucessful oscillation of the proposed oscillator using PLA is confirmed through the experiment. The test vehicle is designed using 0.8 ${\mu}m$ N-well CMOS process and it has a maximum 914MHz oscillation showing -75dBclHz phase noise at 100kHz offset with single 2V supply.

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A Stage Model of Organizational Knowledge Management: A Latent Content Analysis (조직의 지식경영 단계모델 : 잠재내용 분석관점)

  • Lee, Jang-Hwan;Kim, Young-Gul
    • IE interfaces
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    • v.13 no.1
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    • pp.1-9
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    • 2000
  • This study developed an integrated management framework for KM, consisting of four major management objects and organizational initiatives: managerial and technical initiatives. Based on the developed framework, it proposes a stage model of organizational KM from Initiation, Propagation, Integration to Networking stage with detail explanations focusing on management goals and activities. To validate the proposed stage model, this study conducted a preliminary study with a latent content analysis of 15 KM cases. Form the results, though is could not validate the time sequence of each stage because of the limited information of cases, it shows meaningful findings in that there are a kind of relationship among management goals, activities and characteristics of management object of cases.

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A study on the Life Cycle Cost reduction of the LRT's power systems based on the advanced Systems Engineering (시스템엔지니어링 기법 적용에 따른 경량전철 전기시스템의 생명주기비용 절감에 관한 연구)

  • Choi, Won-Chan;Bae, Joon-Ho;Heo, Jae-Hun;Joo, Ji-Young
    • Proceedings of the KSR Conference
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    • 2011.05a
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    • pp.1434-1439
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    • 2011
  • The purpose of this study is based on the optimize the system life cycle cost apply to the advanced systems engineering techniques consideration thought to the system life cycle for the power system which is the one of the major component of the light rail transit system. Generally, the systems engineering techniques apply to the LRT's power systems are not optimize the whole life cycle cost of the power systems because systems engineering management activities are concentrate in performing the key-technology oriented at the construction stage of the dedicated power systems for light rail transit. Through this study, All the stakeholders can be utilize a this advanced systems engineering techniques which is fully considered the life cycle cost through the considering in whole system life cycle (such as concept, design, operation, maintenance and dispose stage as well as construction stage) and adopted by KSX ISO/IEC 15288 system life cycle processes.

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Lived Experience among Patients Newly Diagnosed with Lung Adenocarcinoma Stage IV within One Year

  • Shih, Whei-Mei Jean;Hsu, Hsiu-Chin;Jiang, Ru-Shang;Lin, Mei-Hsiang
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.15
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    • pp.6633-6638
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    • 2015
  • Background: lung cancer (LC) is the fifth of the 10 leading causes of death in the world. LC is in first place for cancer-related mortality for both males and females in Taiwan. It is one of the most difficult cancers to treat and is often diagnosed at a late stage. Patients with stage IV are often unprepared for the diagnosis. Materials and Methods: To explore lived experience among patients newly diagnosed with lung adenocarcinoma stage IV within one year. Results: Twelve participants were recruited in this study. Content analysis of the interviews revealed four themes: (1) emotional roller coaster, (2) trying to find out causes, (3) adjusting my lifestyle, and (4) cancer fighter. Conclusions: This study provides new insight into the experiences of lung cancer patients y with newly diagnosed lung adenocarcinoma stage 4. These results will inform future supportive care service development and intervention research for patients with advanced stage cancer.

Radiotherapy as an effective treatment modality for follicular lymphoma: a single institution experience

  • Choi, Seo Hee;Cho, Jaeho;Kim, Jin Seok;Cheong, June-Won;Suh, Chang-Ok
    • Radiation Oncology Journal
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    • v.33 no.4
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    • pp.310-319
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    • 2015
  • Purpose: Follicular lymphoma (FL) is an indolent non-Hodgkin's lymphoma that is highly sensitive to radiotherapy (RT). However, the effectiveness of RT has not been well established. We reviewed our experiences to assess the role of RT for FL and analyze treatment results. Materials and Methods: Retrospective analysis was done on 29 patients who received first RT between January 2003 and August 2013. Of 23 early stage (stage I, II) patients, 16 received RT alone, four received chemotherapy followed by RT, two received RT postoperatively, and one received salvage RT for relapse after resection. Six advanced-stage (stage III, IV) patients received RT after chemotherapy: two received consolidation RT, three received salvage RT for residual lesions, and one received RT for progressive sites. Median RT dose was 30.6 Gy (range, 21.6 to 48.6 Gy). Median follow-up duration was 62 months (range, 6 to 141 months). Results: All patients showed complete response in the radiation field. Eight outfield relapses were reported. Seven patients received salvage treatment (three chemotherapy, four RT). Four patients showed excellent responses, especially to RT. Estimated 5-year and 10-year relapse-free survivals were 72% and 60%. In the RT-alone group, 5-year relapse-free survival was 74.5%. All advanced-stage patients were disease-free with 100% 5-year overall survival. Disease-specific death was noted in only one patient; four others died of other unrelated causes. No significant toxicity was reported. Conclusion: RT resulted in excellent treatment outcomes for all FL stages when used as a primary treatment modality for early stage or salvage-treatment modality for advanced-stage disease.

Multi-Valued Decision Making for Transitional Stochastic Event: Determination of Sleep Stages through EEG Record

  • Nakamura, Masatoshi;Sugi, Takenaop;Morota, Yukinao;Tachibana, Naoko;Shibasaki, Hiroshi
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.493-493
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    • 2000
  • Multi-valued decision making for transitional stochastic events was newly derived based on conditional probability of database. The two values (on-off) decision making method without transition had been proposed by one of the author in a previous work for a purpose of realizing human on-off decision making. The current method is an extension of the previous on-off decision making. By combining the conditional probability and the transitional probability, the closed form of the algorithm for the multi-valued transitional decision making was derived. The proposed multi-valued decision making was successfully applied to the determination of the five levels of the vigilance of a subject during the EEG recording; awake stage, drowsy stage and sleeping stages (stage 1, stage 2/3, REM (rapid eye movement)). The method for determining the vigilance level can be directly usable for the two purposes; selection of awake EEG segments for automatic EEG interpretation, and determination of sleep stages through sleep EEG. The proposed multi-valued decision making with a mathematical background of the probability can be applicable widely, in industries and in medical fields for purposes of the multi-valued decision making.

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The Structural Model of Nursing Performance for Advanced Beginner-Stage Nurse (상급초보간호사의 간호업무성과 구조모형)

  • Jung, Young Soon;Kim, Hye Sook
    • The Korean Journal of Health Service Management
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    • v.12 no.3
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    • pp.63-78
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    • 2018
  • Objectives: To construct a structural equation model to explain and predict nursing performance in advanced beginner-stage nurses. Methods: This study was conducted from September 1 to October 10, 2017. Participants in this study were 220 nurses recruited from general hospitals with over 300 beds in P and K cities. Confirmatory factor and path analyses were conducted using AMOS 18.0. Results: Nursing performance was affected by self-leadership and self-efficacy; self-efficacy (${\beta}=.794$, p=.025) had a greater effect. Problem-solving competency was affected byself-leadership and self-efficacy ;self-efficacy(${\beta}=.712$, p=.016) had a greater effect. Self-leadership was affected byself-efficacy(${\beta}=.820$, p=.013). Conclusion: Based on the results of this study, it is recommended that a new program be developed and applied to improve advanced beginner-stage nurses' self-leadership and self-efficacy to enhance nursing performance.