• BMB Reports
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• v.52 no.4
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• pp.259-264
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• 2019

Social requirements are needed for living in an aging society and individual longevity. Among them, improved health and medical cares, appropriate for an aging society are strongly demanded. Human cord blood-derived plasma (hUCP) has recently emerged for its unique anti-aging effects. In this study, we investigated brain rejuvenation, particularly olfactory function, that could be achieved by a systemic administration of young blood and its underlying mechanisms. Older than 24-month-old mice were used as an aged group and administered with intravenous injection of hUCP repetitively, eight times. Anti-aging effect of hUCP on olfactory function was evaluated by buried food finding test. To investigate the mode of action of hUCP, brain, serum and spleen of mice were collected for further ex vivo analyses. Systemic injection of hUCP improved aging-associated olfactory deficits, reducing time for finding food. In the brain, although an infiltration of activated microglia and its expression of cathepsin S remarkably decreased, significant changes of proinflammatory factors were not detected. Conversely, peripheral immune balance distinctly switched from predominance of Type 1 helper T (Th1) cells to alternative regulatory T cells (Tregs). These findings indicate that systemic administration of hUCP attenuates age-related neuroinflammation and subsequent olfactory dysfunction by modulating peripheral immune balance toward Treg cells, suggesting another therapeutic function and mechanism of hUCP administration.

• Korean Journal of Community Nutrition
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• v.14 no.2
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• pp.168-174
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• 2009

This study was conducted to investigate the effectiveness of a nutrition and exercise education program on weight control of adult women. The subjects of this study were 28 adult women aged 20-59 years residing in the Daegu area. The nutrition-exercise educational period was 12 weeks. The collected data consisted of items on general characteristics, anthropometric data, blood biochemical values, physical strength data, dietary behavior and nutrition knowledge scores of the subjects. During the 12 weeks of weight control, body mass index(BMI), % of body fat, body fat mass and waist-hip ratio significantly decreased. The level of plasma triglyceride decreased, but not significantly. The level of total cholesterol did not change compared to baseline before the program. After the weight control program, back muscle strength, sit-ups, push-ups, and sit-and-reach tests of the subjects significantly improved. The nutrition knowledge scores of the subjects significantly increased. Therefore, these results suggest that the nutrition-exercise education program may contribute effectively to weight reduction with improvement of physical strength in adult women.

• Korean Journal of Adult Nursing
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• v.19 no.4
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• pp.535-546
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• 2007

Purpose: This study was conducted to evaluate life satisfaction(LS) and to assess the factors that influence LS in senior center elderly people. Methods: The subjects were 253 elders who visited the Y city Senior Welfare Center between July 2006 and August 2006. Data were collected using structured questionnaires. The instruments were composed of Kang's Family Support Scale, Depression Scale by Sheikh & Yesavage, Laffery's Health Concept Scale, and LS scale by Choi. T-test, ANOVA, Duncan test, Pearson coefficients correlation and stepwise multiple regression were used to analyze the data using the SPSS Win 12.0 program. Results: The LS level showed a maximum score of 38 with a mean score of 23.23. The mean scores for depression, health perception and family support were 5.52(maximum score, 15), 77.46(maximum score, 112), 43.45(maximum score, 55) respectively. The LS were significantly correlated with health perception, depression and family support. Depression was the most powerful predictor of and it accounted for 42.0% of the total variance in LS. A combination of significance of eudaimonistic health perception and satisfaction with pocket money accounted for 47.2% in LS. Conclusion: Depression and health perception were identified as affecting variables for the LS. Based upon these results, nurses should help the aged to enhance their LS.

• Korean Journal of Community Nutrition
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• v.12 no.4
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• pp.477-488
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• 2007

Prevalence of an obese population has been increasing in Korea. Obesity is considered a major risk factor for chronic degenerative diseases. Specifically, prevalence of obesity is prominent for adult woman in Korea. In many weight control programs, weight change did not often show any beneficial effects for health. These facts discourage people in the program. Thus in this study, the anthropometry, blood pressure, serum biochemical indices and dietary habits were compared by percent body fat change for adult women to show the beneficial effects of the weight control program. Study subjects were 134. Measurements were done before and after the weight control program. Percent Body Fat (PBF) was measured by bioelectrical impedance analysis. Using PBF changes, subjects were grouped as I (more than 1% increase), M (${\pm}1%$ change), and D (more than 1% decrease). Data were analyzed using SPSS 12.0 program. Among the 134 participants, 13 increased their weight and 100 decreased. For PBF, 19 increased and 59 decreased. Statistical significant differences were shown for anthropometric assessments before and after for all weight, fat mass, percent body fat, waist-hip ratio and body mass index. I had increases, and D shows decreases. But the difference of D is large than M. Systolic and diastolic blood pressures decreased in all groups (p < 0.05). Fasting blood glucose decreased in all groups but were statistically significant only in D. Also triglyceride decreased in D (p < 0.05). Thus health conditions showed desirable changes in I < M < D in order. Dietary habit changes were desirable with only D. Weight, BMI and other indicators for obesity is not the real indicator for PBF. Recently it is easy to measure PBF. Thus, for weight control programs and to show benefits of the program, PBF is a good indicator for adult women in Korea.

• Journal of Korean Academy of Nursing
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• v.37 no.4
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• pp.613-623
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• 2007

Purpose: The purpose of this study was to describe the operation, staffing, and services provided at adult day care centers in Korea. Methods: The study was a cross-sectional descriptive survey. The subjects were 209 centers among 280 centers registered in Korea (response rate 74.6%). The data was collected from August to December in 2006. Results: 48.8% of centers were located in a city area. The centers were based on the Social Model 65.5% of the centers were open Monday to Friday, an average of $7{\sim}8$ hours per day Dementia, stroke or frail elderly could use the center, and 57.4% of centers were used for dementia and stroke elderly together. The enrollment of elderly was 13.5. The number of total staff was 8.27, the number of RN's and social workers was 0.67, and 2.54 respectively. The social services(Meal preparation 98.6%, Special event 98.1%, Transportation, 97.1%) were provided more than the health services(Physical therapy 98.1%, ADL training 95.2%, Counseling 84 7%, Vaccination 82.8%, Health monitoring 78.9%, Health education 78.5%, Bathing 66.1%, and Speech therapy 28.2%). Conclusion: These results suggest we have to develop a health-focused adult day health care model based on the needs of elderly and their families. Nurses will have an important role in adult day health care.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.21 no.1
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• pp.11-16
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• 2010

This review aimed to assist clinicians in the identification and assessment of adult attention-deficit hyperactivity disorder (ADHD) with an emphasis on diagnostic and rating instruments. Pubmed and RISS were utilized to identify relevant studies and critical reviews on the diagnosis and assessment of adult ADHD, published between 1988 and 2010. The Adult ADHD Self-Report Scale-v1.1, the ADHD Rating Scale-IV, the Conners Adult ADHD Rating Scale, and the Current Symptoms Scale have been utilized for self-reporting of current ADHD symptoms. The Brown ADD Rating Scale, the ADHD Rating Scale-IV, the Current Symptoms Scale, and the Conners Adult ADHD Rating Scale have also been evaluated by an observer. The Childhood Symptom Scale and the Wender-Utah Rating Scale have been used for retrospective assessment of childhood ADHD symptoms and the Adult ADHD Investigator Symptom Rating Scale, the Adult Interview, the Brown ADD Diagnostic Form, the Conners adult ADHD diagnostic interview for DSM-IV, and the Wender-Reimherr Interview have been available as comprehensive diagnostic interviews. There is a wide variety of instruments available with respect to adult ADHD. The choice of appropriate instruments is essential for achieving accurate diagnosis and assessment of this disorder.

• Korean Journal of Adult Nursing
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• v.27 no.4
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• pp.428-437
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• 2015

Purpose: The aim of this study was to describe health status and to identify the factors related to health behavior in older adults in South Korea. Methods: A cross-sectional survey was conducted with a convenience sample of 186 older people (mean age =68.2yrs, 65.1% Female) registered at one senior center. Data were collected by self-report questionnaires or through face to face interview. The instruments were the Modified Health Behavior Assessment Scale, Stanford Research Instruments for Chronic Disease, Self-Efficacy, SOF Frailty Index and Quality of life questionnaire. The data were analyzed using t-test, ANOVA, Pearson's correlation, and stepwise multiple regression. Results: 58.6% older adults perceived their health status positively. Education level and economic status were significantly related to health behaviors of older adults. Self-rated health, sleep, stress, quality of life, health distress, depression, and frailty were significantly correlated with the health behaviors of older adults. Frailty, education level, and sleep disturbance were the significant factors predicting the health behaviors. Conclusion: The findings from this study suggest that nurses should take into consideration education level of older adults to promote their health behaviors and health promotion program which focuses on maintaining the quality of sleep and preventing frailty.

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2004.05a
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• pp.103-104
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• 2004

• Journal of Korean Academy of Nursing
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• v.36 no.5
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• pp.691-700
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• 2006

Purpose: This study was done to analyze variations in unit staffing and recommend policies to improve nursing staffing levels in intensive care units (ICUS). Method: A cross-sectional study design was used, employing survey data from the Health Insurance Review Agency conducted from June-July, 2003. Unitstaffing was measured using two indicators; bed-to-nurse (B/N) ratio (number of beds per nurse), and patient-to-nurse (P/N) ratio (number of average daily patients per nurse). Staffing levels were compared according to hospital and ICU characteristics. Result: A total of 414 institutions were operating 569 adult and 86 neonatal ICUs. Tertiary hospitals (n=42) had the lowest mean B/N (0.82) and P/N (0.76) ratios in adult ICUs, followed by general hospitals (B/N: 1.34, P/N: 0.97). Those ratios indicated that a nurse took care of 3 to 5 patients per shift. Neonatal ICUs had worse staffing and had greater variations in stafnng ratios than adult ICUs. About 17% of adult and 26% of neonatal ICUs were staffed only by adjunct nurses who had responsibility for a general ward as well as the ICU Conclusion: Stratification of nurse staffing levels and differentiation of ICU utilization fees based on staffing grades are recommended as a policy tool to improve nurse staffing in ICUs.

• Korean Journal of Adult Nursing
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• v.16 no.4
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• pp.575-584
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• 2004

Purpose: To describe the performance in the health-promoting lifestyle and to identify the major factors affecting the health-promoting relationships between self care behaviors and health promoting lifestyle profile in patients with pulmonary tuberculosis. Method: A convenience sample for this study was 172 pulmonary tuberculosis patients who have taken TB medications in urban city. The HPLP-II was selected to measure the concept of health-promoting lifestyle because of the number of research studies conducted using both the original HPLP and the revised HPLP-II. The statistical methods used in this study were t-test, ANOVA, Pearson correlations, and multiple regression. Result: The differences of the HPLP-II were found to have a significance of age, marital status, education level, and health service center. The level of self care behaviors was related positively to the level of health promoting lifestyle and their subcategories. Based on stepwise multiple regression analysis, the model that predicted factors included self care behaviors, age, health service center and education. Conclusion: After decades of decreasing rates, TB has reemerged as a serious national problem in Korea. The careful clinical management and more national concern of TB may help to improve the outcomes of many patients. The findings of this study suggest that TB patients who are more fulfilled in health-promoting lifestyles and self-care behaviors may be able to make better decisions regarding positive health-promoting behaviors.