• Molecules and Cells
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• v.20 no.2
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• pp.288-296
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• 2005

Cytokines interleukin (IL) 12 and 23 play critical roles in linking innate and adaptive immune responses. They are members of heterodimeric cytokines, sharing a subunit p40. Although IL12/23 p40 is mainly induced in macrophages and dendritic cells (DCs) after stimulation with microbial Toll-like receptor ligands, methods to monitor the cells that produce IL12/23 p40 in vivo are limited. Recently, the mouse model to track p40-expressing cells with fluorescent reporter, yellow fluorescent protein, has been developed. Macrophages and DCs from these mice faithfully reported p40 induction using the fluorescent marker. Here we took advantage of these reporter mice to screen bio-compounds for p40-inducing activity. After screening hundreds of compounds, we found several extracts inducing IL12/23 p40 gene expression. Treatment of DCs with these extracts induced the expression of MHC class II and co-stimulatory molecules, which implies that these might be useful as adjuvants. Next, the in vivo target immune cells of candidate compounds were examined. The reporter system can be useful to identify cells producing IL12 or IL23 in vivo as well as in vitro. Thus, our cytokine reporter system proved to be a valuable reagent for screening for immunostimulatory molecules and identification of target cells in vivo.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.41 no.3
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• pp.103-114
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• 2004

This paper deals with a system that is capable of recognizing hand-signals in 3-dimensional space. The system uses 2 color cameras as input devices. Vision-based gesture recognition system is known to be user-friendly because of its contact-free characteristic. But as with other applications using a camera as an input device, there are difficulties under complex background and varying illumination. In order to detect hand region robustly from a input image under various conditions without any special gloves or markers, the paper uses previous position information and adaptive hand color model. The paper defines a hand-signal as a combination of two basic elements such as 'hand pose' and 'hand trajectory'. As an extensive classification method for hand pose, the paper proposes 2-stage classification method by using 'small group concept'. Also, the paper suggests a complementary feature selection method from images from two color cameras. We verified our method with a hand-signal application to our driving simulator.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.49 no.1
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• pp.58-66
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• 2012

Even after establishment of H.264/AVC standard, the video coding experts group (VCEG) of ITU-T has researched on development of promising coding techniques to increase coding efficiency based on the key technology area (KTA) software. Recently, the joint collaboration team video coding (JCT-VC) which was composed of the VCEG and the motion picture experts group (MPEG) of ISO/IEC is developing a next-generation video standard namely HEVC intended to gain twice efficiency than H.264/AVC. An adaptive interpolation technique, one of various next-generation techniques, reported higher coding efficiency. However, it has high computational complexity and does not deal with various error characteristics for videos. In this paper, we investigate characteristics of interpolation filters and propose an effective fixed interpolation filter bank including diverse properties of error. Experimental results is shown that the proposed method achieved bitrate reduction by 0.7% and 1.3% compared to fixed directional interpolation filter (FDIF) of the KTA and the directional interpolation filter (DIF) of the HEVC test model, respectively.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.45 no.2
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• pp.103-110
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• 2008

When there is uncertainty in topological rate of change, motility model and terrain condition, the performance severely degrades in MANET. The concept of transition of routing protocol on the fly according to the network parameters such as coverage, connectivity and mobility etc. may counterbalance the problems stated above. The mathematical modeling of feedback parameters has been derived, and the architecture for the multi-routing protocol system providing an adaptation from one routing protocol to another is also investigated. This paper is extensively devoted on the analysis of mobility, connectivity and their effects on the network and finally transition into another routing protocol according to them.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37 no.4C
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• pp.277-282
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• 2012

In this paper, we present a real-time eye contact system for realistic telepresence using a Kinect depth camera. In order to generate the eye contact image, we capture a pair of color and depth video. Then, the foreground single user is separated from the background. Since the raw depth data includes several types of noises, we perform a joint bilateral filtering method. We apply the discontinuity-adaptive depth filter to the filtered depth map to reduce the disocclusion area. From the color image and the preprocessed depth map, we construct a user mesh model at the virtual viewpoint. The entire system is implemented through GPU-based parallel programming for real-time processing. Experimental results have shown that the proposed eye contact system is efficient in realizing eye contact, providing the realistic telepresence.

• Computational Structural Engineering
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• v.10 no.4
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• pp.217-228
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• 1997

The high precision analysis by the p-version of the finite element method are fairly well established as highly efficient method for linear elastic problems, especially in the presence of stress singularity. It has been noted that the merits of the p-version are accuracy, modeling simplicity, robustness, and savings in user's and CPU time. However, little has been done to exploit their benefits in elasto-plastic analysis. In this paper, the p-version finite element model is proposed for the materially nonlinear analysis that is based on the incremental theory of plasticity using the constitutive equation for work-hardening materials, and the associated flow rule. To obtain the solution of nonlinear equation, the Newton-Raphson method and initial stiffness method, etc are used. Several numerical examples are tested with the help of the square plates with cutout, the thick-walled cylinder under internal pressure, and the circular plate with uniformly distributed load. Those results are compared with the theoretical solutions and the numerical solutions of ADINA

• Transactions of the Korean Society of Mechanical Engineers A
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• v.40 no.9
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• pp.783-790
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• 2016

One of the main factors related to the deterioration of estimation accuracy in inertial measurement unit (IMU)-based orientation determination is the object's acceleration. This is because accelerometer signals under accelerated motion conditions cannot be longer reference vectors along the vertical axis. In order to deal with this issue, some orientation estimation algorithms adopt acceleration-compensating mechanisms. Such mechanisms include the simple switching techniques, mechanisms with adaptive estimation of acceleration, and acceleration model-based mechanisms. This paper compares these three mechanisms in terms of estimation accuracy. From experimental results under accelerated dynamic conditions, the following can be concluded. (1) A compensating mechanism is essential for an estimation algorithm to maintain accuracy under accelerated conditions. (2) Although the simple switching mechanism is effective to some extent, the other two mechanisms showed much higher accuracies, particularly when test conditions were severe.

• Journal of the Korea Society of Computer and Information
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• v.17 no.6
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• pp.75-81
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• 2012

This paper has proposed Message Count Control Mechanism based Link State Update(LSU) Algorithm that has not had a strong influence on the depreciation of QoS routing performance. Most existing LSU algorithms have the limit that cannot control the count of LSU message. Especially, adaptive algorithms have a bad performance when traffic are excessive and fickle. We classify as the importance of LSU message that have a influence on available bandwidth and determine the transmission of the message according to update rate per a unit of time. We have evaluated the performance of the proposed model and the existing algorithms on MCI simulation network using the performance metric as the QoS routing blocking rate and the mean update rate per link, it thus appears that we have verified the performance of this algorithm.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.39 no.2
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• pp.69-78
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• 2002

This paper addresses a method to automatically detect out a person's face from a given image that consists of a hair and face view of the person and a complex background scene. Out method involves an effective detection algorithm that exploits the spatial distribution characteristics of human skin color via an adaptive fuzzy color classifier (AFCC), The universal skin-color map is derived on the chrominance component of human skin color in Cb, Cr and their corresponding luminance. The desired fuzzy system is applied to decide the skin color regions and those that are not. We use RGB model for extracting the hair color regions because the hair regions often show low brightness and chromaticity estimation of low brightness color is not stable. After some preprocessing, we apply convex-hull to each region. Consequent face detection is made from the relationship between a face's convex-hull and a head's convex-hull. The algorithm using the convex-hull shows better performance than the algorithm using pattern method. The performance of the proposed algorithm is shown by experiment. Experimental results show that the proposed algorithm successfully and efficiently detects the faces without constrained input conditions in color images.

• Journal of Korean Biological Nursing Science
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• v.17 no.1
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• pp.37-43
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• 2015

Purpose: Stress, depending on its intensity and duration, results in either adaptive or maladaptive physiological and psychological changes in humans. Also, it was found that stressful experiences increase the signs of behavioral despair in rodents. On the other hand, exercise and melatonin treatment is believed to have many beneficial effects on health. Thus, this study was designed to evaluate the anti-depressant effects of physical activity and melatonin against chronic stress-induced depression in rats. Methods: Adult male Sprague-Dawley(SD) rats(200-250g, 7 weeks of age) were subjected to depression induced by chronic stress. Chronic depression was induced with forced-swim stress (FSS) and repeated change of light-dark cycle for 4 weeks. In the last 2 weeks, some rats were confined in a cage enriched with a running wheel, seesaw and chewed a ball from 19:00 to 07:00 every day. Melatonin was injected intra-peritoneally (I.P), and the rats received intraperitoneal injections of melatonin (15 mg/kg). The Forced Swim Test (FST) was performed to evaluate the immobility behaviors of rats for a 5 min test. Results: It was found that, the immobility time in FST was significantly (p<.05) lower in physical exercise ($M=58.83{\pm}22.73$) and melatonin ($M=67.33{\pm}37.73$) than in depressive rats ($M=145.93{\pm}63.16$) without physical activity. Also, TPH positive cell in dorsal raphe was significantly (p<.05) higher in exercise ($M=457.38{\pm}103.21$) and melatonin ($M=425.38{\pm}111.56$) than in depressive rats ($M=258.25{\pm}89.13$). Conclusion: This study suggests that physical activity and melatonin produces antidepressant-like effect on stress-induced depression in rats. So, physical exercise and melatonin may be a good intervention in depression patients.