Cytokine Reporter Mouse System for Screening Novel IL12/23 p40-inducing Compounds
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Im, Wooseok
(Department of Bioscience and Biotechnology, Sejong University)
Kim, Hyojeong (Department of Bioscience and Biotechnology, Sejong University) Yun, Daesun (Department of Bioscience and Biotechnology, Sejong University) Seo, Sung-Yum (Department of Life Science, Kongju National University) Park, Se-Ho (School of Biotechnology, Korea University) Locksley, Richard M. (Howard Hughes Medical Institute and Department of Medicine and Microbiology & Immunology, University of California) Hong, Seokmann (Department of Bioscience and Biotechnology, Sejong University) |
1 | Akira, S. and Takeda, K. (2004) Toll-like receptor signalling. Nat. Rev. Immunol. 4, 499-511 DOI ScienceOn |
2 | Ardavin, C., Amigorena, S., and Reis e Sousa, C. (2004) Dendritic cells: immunobiology and cancer immunotherapy. Immunity 20, 17-23 DOI ScienceOn |
3 | Banchereau, J., Fay, J., Pascual, V., and Palucka, A. K. (2003) Dendritic cells: controllers of the immune system and a new promise for immunotherapy. Novartis. Found. Symp. 252, 226-235; discussion 235-228, 257-267 |
4 | Brasel, K., De Smedt, T., Smith, J. L., and Maliszewski, C. R. (2000) Generation of murine dendritic cells from flt3-ligandsupplemented bone marrow cultures. Blood 96, 3029-3039 |
5 | Hoebe, K., Janssen, E., and Beutler, B. (2004) The interface between innate and adaptive immunity. Nat. Immunol. 5, 971-974 DOI ScienceOn |
6 | Iwasaki, A. and Medzhitov, R. (2004) Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5, 987-995 DOI ScienceOn |
7 | Liu, Y. J. (2001) Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106, 259-262 DOI ScienceOn |
8 | Trinchieri, G. and Scott, P. (1995) Interleukin-12: a proinflammatory cytokine with immunoregulatory functions. Res. Immunol. 146, 423-431 DOI ScienceOn |
9 | Visser, L., Jan de Heer, H., Boven, L. A., van Riel, D., van Meurs, M., et al. (2005) Proinflammatory bacterial peptidoglycan as a cofactor for the development of central nervous system autoimmune disease. J. Immunol. 174, 808-816 |
10 | Wang, S., Zhu, G., Chapoval, A. I., Dong, H., Tamada, K., et al. (2000) Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS. Blood 96, 2808-2813 |
11 | Trinchieri, G. (2003) Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3, 133-146 DOI ScienceOn |
12 | Trinchieri, G. and Scott, P. (1999) Interleukin-12: basic principles and clinical applications. Curr. Top Microbiol. Immunol. 238, 57-78 |
13 | Schuler, G., Schuler-Thurner, B., and Steinman, R. M. (2003) The use of dendritic cells in cancer immunotherapy. Curr. Opin. Immunol. 15, 138-147 DOI ScienceOn |
14 | Cua, D. J., Sherlock, J., Chen, Y., Murphy, C. A., Joyce, B., et al. (2003) Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421, 744-748 DOI ScienceOn |
15 | Kawai, T. and Akira, S. (2005) Toll-like receptor downstream signaling. Arthritis Res. Ther. 7, 12-19 DOI ScienceOn |
16 | Langrish, C. L., McKenzie, B. S., Wilson, N. J., de Waal Malefyt, R., Kastelein, R. A., et al. (2004) IL-12 and IL-23: master regulators of innate and adaptive immunity. Immunol. Rev. 202, 96-105 DOI ScienceOn |
17 | Blattman, J. N. and Greenberg, P. D. (2004) Cancer immunotherapy: a treatment for the masses. Science 305, 200-205 DOI ScienceOn |
18 | Takeda, K. and Akira, S. (2004b) TLR signaling pathways. Semin. Immunol. 16, 3-9 DOI ScienceOn |
19 | Wilson, H. L. and O'Neill, H. C. (2003) Murine dendritic cell development: difficulties associated with subset analysis. Immunol. Cell. Biol. 81, 239-246 DOI ScienceOn |
20 | Wilczynski, J. R. (2005) Th1/Th2 cytokines balance-yin and yang of reproductive immunology. Eur. J. Obstet. Gynecol. Reprod. Biol. (in press) |
21 | Takeda, K. and Akira, S. (2004a) Microbial recognition by Tolllike receptors. J. Dermatol. Sci. 34, 73-82 DOI ScienceOn |
22 | Kopp, T., Lenz, P., Bello-Fernandez, C., Kastelein, R. A., Kupper, T. S., et al. (2003) IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: evidence for enhanced cutaneous immunity. J. Immunol. 170, 5438-5444 |
23 | Diamond, B. (2005) Autoimmunity. Immunol. Rev. 204, 5-8 DOI ScienceOn |
24 | Fortier, A. H., Hoover, D. L., and Nacy, C. A. (1982) Intracellular replication of Leishmania tropica in mouse peritoneal macrophages: amastigote infection of resident cells and inflammatory exudate macrophages. Infect. Immun. 38, 1304-1308 |
25 | Steinman, L. (2004) Immune therapy for autoimmune diseases. Science 305, 212-216 DOI ScienceOn |
26 | van de Vosse, E., Lichtenauer-Kaligis, E. G., van Dissel, J. T., and Ottenhoff, T. H. (2003) Genetic variations in the interleukin- 12/interleukin-23 receptor (beta1) chain, and implications for IL-12 and IL-23 receptor structure and function. Immunogenetics 54, 817-829 |
27 | Zuniga, E. I., McGavern, D. B., Pruneda-Paz, J. L., Teng, C., and Oldstone, M. B. (2004) Bone marrow plasmacytoid dendritic cells can differentiate into myeloid dendritic cells upon virus infection. Nat. Immunol. 5, 1227-1234 DOI ScienceOn |
28 | Takeda, K. and Akira, S. (2005) Toll-like receptors in innate immunity. Int. Immunol. 17, 1-14 |
29 | Gately, M. K., Desai, B. B., Wolitzky, A. G., Quinn, P. M., Dwyer, C. M., et al. (1991) Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor). J. Immunol. 147, 874-882 |
30 | O'Neill, L. A. (2004) Immunology. After the toll rush. Science 303, 1481-1482 DOI ScienceOn |
31 | Stetson, D. B., Mohrs, M., Reinhardt, R. L., Baron, J. L., Wang, Z. E., et al. (2003) Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J. Exp. Med. 198, 1069-1076 DOI ScienceOn |
32 | Gilliet, M., Boonstra, A., Paturel, C., Antonenko, S., Xu, X. L., et al. (2002) The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3- ligand and granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 195, 953-958 DOI |
33 | Langrish, C. L., Chen, Y., Blumenschein, W. M., Mattson, J., Basham, B., et al. (2005) IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201, 233240 DOI ScienceOn |
34 | Shortman, K. and Liu, Y. J. (2002) Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2, 151-161 DOI ScienceOn |
35 | Oppmann, B., Lesley, R., Blom, B., Timans, J. C., Xu, Y., et al. (2000) Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 13, 715-725 DOI ScienceOn |
36 | Banchereau, J. and Steinman, R. M. (1998) Dendritic cells and the control of immunity. Nature 392, 245-252 DOI ScienceOn |
37 | Pasare, C. and Medzhitov, R. (2004) Toll-like receptors: linking innate and adaptive immunity. Microbes Infect. 6, 1382-1387 DOI ScienceOn |
38 | Colonna, M., Trinchieri, G., and Liu, Y. J. (2004) Plasmacytoid dendritic cells in immunity. Nat. Immunol. 5, 1219-1226 DOI ScienceOn |
39 | Watford, W. T., Moriguchi, M., Morinobu, A., and O'Shea, J. J. (2003) The biology of IL-12: coordinating innate and adaptive immune responses. Cytokine Growth Factor Rev. 14, 361-368 DOI ScienceOn |
40 | Dalod, M., Hamilton, T., Salomon, R., Salazar-Mather, T. P., Henry, S. C., et al. (2003) Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/ beta. J. Exp. Med. 197, 885-898 DOI ScienceOn |
41 | Steinman, R. M. and Mellman, I. (2004) Immunotherapy: bewitched, bothered, and bewildered no more. Science 305, 197-200 DOI ScienceOn |
42 | Becher, B., Durell, B. G., and Noelle, R. J. (2003) IL-23 produced by CNS-resident cells controls T cell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis. J. Clin. Invest. 112, 1186-1191 |
43 | Abbas, A. K., Murphy, K. M., and Sher, A. (1996) Functional diversity of helper T lymphocytes. Nature 383, 787-793 DOI ScienceOn |
44 | Mohrs, M., Shinkai, K., Mohrs, K., and Locksley, R. M. (2001) Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter. Immunity 15, 303311 DOI ScienceOn |
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