• Title/Summary/Keyword: adaptive method

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Evaluation of MR-SENSE Reconstruction by Filtering Effect and Spatial Resolution of the Sensitivity Map for the Simulation-Based Linear Coil Array (선형적 위상배열 코일구조의 시뮬레이션을 통한 민감도지도의 공간 해상도 및 필터링 변화에 따른 MR-SENSE 영상재구성 평가)

  • Lee, D.H.;Hong, C.P.;Han, B.S.;Kim, H.J.;Suh, J.J.;Kim, S.H.;Lee, C.H.;Lee, M.W.
    • Journal of Biomedical Engineering Research
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    • v.32 no.3
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    • pp.245-250
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    • 2011
  • Parallel imaging technique can provide several advantages for a multitude of MRI applications. Especially, in SENSE technique, sensitivity maps were always required in order to determine the reconstruction matrix, therefore, a number of difference approaches using sensitivity information from coils have been demonstrated to improve of image quality. Moreover, many filtering methods were proposed such as adaptive matched filter and nonlinear diffusion technique to optimize the suppression of background noise and to improve of image quality. In this study, we performed SENSE reconstruction using computer simulations to confirm the most suitable method for the feasibility of filtering effect and according to changing order of polynomial fit that were applied on variation of spatial resolution of sensitivity map. The image was obtained at 0.32T(Magfinder II, Genpia, Korea) MRI system using spin-echo pulse sequence(TR/TE = 500/20 ms, FOV = 300 mm, matrix = $128{\times}128$, thickness = 8 mm). For the simulation, obtained image was multiplied with four linear-array coil sensitivities which were formed of 2D-gaussian distribution and the image was complex white gaussian noise was added. Image processing was separated to apply two methods which were polynomial fitting and filtering according to spatial resolution of sensitivity map and each coil image was subsampled corresponding to reduction factor(r-factor) of 2 and 4. The results were compared to mean value of geomety factor(g-factor) and artifact power(AP) according to r-factor 2 and 4. Our results were represented while changing of spatial resolution of sensitivity map and r-factor, polynomial fit methods were represented the better results compared with general filtering methods. Although our result had limitation of computer simulation study instead of applying to experiment and coil geometric array such as linear, our method may be useful for determination of optimal sensitivity map in a linear coil array.

Hardware optimized high quality image signal processor for single-chip CMOS Image Sensor (Single-chip CMOS Image Sensor를 위한 하드웨어 최적화된 고화질 Image Signal Processor 설계)

  • Lee, Won-Jae;Jung, Yun-Ho;Lee, Seong-Joo;Kim, Jae-Seok
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.44 no.5
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    • pp.103-111
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    • 2007
  • In this paper, we propose a VLSI architecture of hardware optimized high quality image signal processor for a Single-chip CMOS Image Sensor(CIS). The Single-chip CIS is usually used for mobile applications, so it has to be implemented as small as possible while maintaining the image quality. Several image processing algorithms are used in ISP to improve captured image quality. Among the several image processing blocks, demosaicing and image filter are the core blocks in ISP. These blocks need line memories, but the number of line memories is limited in a low cost Single-chip CIS. In our design, high quality edge-adaptive and cross channel correlation considered demosaicing algorithm is adopted. To minimize the number of required line memories for image filter, we share the line memories using the characteristics of demosaicing algorithm which consider the cross correlation. Based on the proposed method, we can achieve both high quality and low hardware complexity with a small number of line memories. The proposed method was implemented and verified successfully using verilog HDL and FPGA. It was synthesized to gate-level circuits using 0.25um CMOS standard cell library. The total logic gate count is 37K, and seven and half line memories are used.

Robust Orientation Estimation Algorithm of Fingerprint Images (노이즈에 강인한 지문 융선의 방향 추출 알고리즘)

  • Lee, Sang-Hoon;Lee, Chul-Han;Choi, Kyoung-Taek;Kim, Jai-Hie
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.45 no.1
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    • pp.55-63
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    • 2008
  • Ridge orientations of fingerprint image are crucial informations in many parts of fingerprint recognition such as enhancement, matching and classification. Therefore it is essential to extract the ridge orientations of image accurately because it directly affects the performance of the system. The two main properties of ridge orientation are 1) global characteristic(gradual change in whole part of fingerprint) and 2) local characteristic(abrupt change around core and delta points). When we only consider the local characteristic, estimated ridge orientations are well around singular points but not robust to noise. When the global characteristic is only considered, to estimate ridge orientation is robust to noise but cannot represent the orientation around singular points. In this paper, we propose a novel method for estimating ridge orientation which represents local characteristic specifically as well as be robust to noise. We reduce the noise caused by scar using iterative outlier rejection. We apply adaptive measurement resolution in each fingerprint area to estimate the ridge orientation around singular points accurately. We evaluate the performance of proposed method using synthetic fingerprint and FVC 2002 DB. We compare the accuracy of ridge orientation. The performance of fingerprint authentication system is evaluated using FVC 2002 DB.

An Artificial Visual Attention Model based on Opponent Process Theory for Salient Region Segmentation (돌출영역 분할을 위한 대립과정이론 기반의 인공시각집중모델)

  • Jeong, Kiseon;Hong, Changpyo;Park, Dong Sun
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.7
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    • pp.157-168
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    • 2014
  • We propose an novel artificial visual attention model that is capable of automatic detection and segmentation of saliency region on natural images in this paper. The proposed model is based on human visual perceptions in biological vision and contains there are main contributions. Firstly, we propose a novel framework of artificial visual attention model based on the opponent process theory using intensity and color features, and an entropy filter is designed to perceive salient regions considering the amount of information from intensity and color feature channels. The entropy filter is able to detect and segment salient regions in high segmentation accuracy and precision. Lastly, we also propose an adaptive combination method to generate a final saliency map. This method estimates scores about intensity and color conspicuous maps from each perception model and combines the conspicuous maps with weight derived from scores. In evaluation of saliency map by ROC analysis, the AUC of proposed model as 0.9256 approximately improved 15% whereas the AUC of previous state-of-the-art models as 0.7824. And in evaluation of salient region segmentation, the F-beta of proposed model as 0.7325 approximately improved 22% whereas the F-beta of previous state-of-the-art models.

A Cell Loss Constraint Method of Bandwidth Renegotiation for Prioritized MPEG Video Data Transmission in ATM Networks (ATM망에서 우선 순위가 주어진 MPEG 비디오 데이터 전송시 대역폭 재협상을 통한 셀 손실 방지 기법)

  • Yun, Byoung-An;Kim, Eun-Hwan;Jun, Moon-Seog
    • The Transactions of the Korea Information Processing Society
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    • v.4 no.7
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    • pp.1770-1780
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    • 1997
  • Our problem is improvement of image quality because it is inevitable cell loss of image data when traffic congestion occurs. If cells are discarded indiscriminately in transmission of MPEG video data, it occurs severe degradation in quality of service(QOS). In this paper, to solve this problem, we propose two method. The first, we analyze the traffic characteristics of an MPEG encoder and generate high priority and low priority data stream. During network congestion, only the least low priority cells are dropped, and this ensures that the high priority cells are successfully transmitted, which, in turn, guarantees satisfactory QoS. In this case, the prioritization scheme for the encoder assigns components of the data stream to each priority level based on the value of a parameter ${\beta}$. The second, Number of high priority cells are increased when value of ${\beta}$ is large. It occurs the loss of high priority cell in the congestion. To prevent it, this paper is regulated to data stream rate as buffer occupancy with UPC controller. Therefore, encoder's bandwidth can be calculated renegotiation of the encoder and networks. In this paper, the encoder's bandwidth requirements are characterized by a usage parameter control (UPC) set consisting of peak rate, burstness, and sustained rate. An adaptive encoder rate control algorithm at the Networks Interface Card(NIC) computes the necessary UPC parameter to maintain the user specified quality of service. Simulation results are given for a rate-controlled VBR video encoder operating through an ATM network interface which supports dynamic UPC. These results show that dynamic bandwidth renegotiation of prioritized data stream could provided bandwidth saving and significant quality gains which guarantee high priority data stream.

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The Proposal of Evaluation Method for Local Government Infrastructure Vulnerability Relating to Climate Change Driven Flood (기후변화에 따른 홍수에 대한 지자체 기반시설 취약성 평가 방법 제시)

  • Han, Woo Suk;Sim, Ou Bae;Lee, Byoung Jae;Yoo, Jae Hwan
    • Journal of Climate Change Research
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    • v.3 no.1
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    • pp.25-37
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    • 2012
  • This research proposes the direction for the assessment of local government infrastructure vulnerabilities relating to climate change driven flood and analyzes the assessment result. In this research, the local government infrastructures are evaluated by three indices such as exposure, infrastructure sensitivity, adaptive capacity and each index is calculated by selected alternative variable. Climate change scenario(A1B) developed on National Institute of Environmental Research is used to calculate present and future(2020, 2050, 2100s) exposure. As the result of infrastructure vulnerability assessment on present, the infrastructures in Seoul, Northern Gyeonggi-do, Gangwon-do, coastal area of Gyeongsangnam-do are vulnerable to flooding. For future, although the spatial pattern of flooding vulnerable infrastructure are similar, the flooding vulnerabilities of infrastructure in Gyeonggido and Ganwon-do would be increased as close to 2100s. It is expected that this research can be utilized as the preliminary analysis for climate change adaptation in local government infrastructure because this research propose the method for the assessment of local government infrastructure vulnerability relating to climate change driven flood and the result such as a trend of infrastructure vulnerability to flooding and the level of contribution of each index and alternative variable.

Systematic Review of Method for Application of Oral Sensorimotor Intervention for Feeding Disorders in Children with Cerebral Palsy (섭식 장애가 있는 뇌성마비 아동에게 적용된 구강감각운동치료방법에 대한 체계적 고찰)

  • Seo, Sang-Min;Min, Kyung-Chul
    • Therapeutic Science for Rehabilitation
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    • v.8 no.3
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    • pp.31-41
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    • 2019
  • Objective: This study was conducted to comprehensively analyze domestic and international literature on the oral sensorimotor intervention approaches and evaluation/non-instrumental assessment methods for children with cerebral palsy with feeding disorders. Methods: One hundred and seventy-six papers published from January 2009 to December 2018 were screened. Forty-seven papers were selected based on the abstract and title, and five papers were selected through a secondary search. Results: The PEDro scale of the selected papers was high with an average of 7 points, and the therapeutic intervention period was found to be between 2 and 6 months, providing therapeutic interventions once to 5 times a week, at least 15 minutes to 1 hour a day. The treatment approach was used with impairment-based intervention and adaptive-based intervention, and the assessment method was divided into clinical evaluation and non-instrumental assessments. Conclusion: Through this systematic review, we found that there are a variety of oral sensorimotor interventions for children with cerebral palsy with feeding disorders. This study provides support for planning oral sensorimotor intervention programs for occupational therapy in clinical practice for children with cerebral palsy.

Urban Change Detection for High-resolution Satellite Images Using U-Net Based on SPADE (SPADE 기반 U-Net을 이용한 고해상도 위성영상에서의 도시 변화탐지)

  • Song, Changwoo;Wahyu, Wiratama;Jung, Jihun;Hong, Seongjae;Kim, Daehee;Kang, Joohyung
    • Korean Journal of Remote Sensing
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    • v.36 no.6_2
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    • pp.1579-1590
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    • 2020
  • In this paper, spatially-adaptive denormalization (SPADE) based U-Net is proposed to detect changes by using high-resolution satellite images. The proposed network is to preserve spatial information using SPADE. Change detection methods using high-resolution satellite images can be used to resolve various urban problems such as city planning and forecasting. For using pixel-based change detection, which is a conventional method such as Iteratively Reweighted-Multivariate Alteration Detection (IR-MAD), unchanged areas will be detected as changing areas because changes in pixels are sensitive to the state of the environment such as seasonal changes between images. Therefore, in this paper, to precisely detect the changes of the objects that consist of the city in time-series satellite images, the semantic spatial objects that consist of the city are defined, extracted through deep learning based image segmentation, and then analyzed the changes between areas to carry out change detection. The semantic objects for analyzing changes were defined as six classes: building, road, farmland, vinyl house, forest area, and waterside area. Each network model learned with KOMPSAT-3A satellite images performs a change detection for the time-series KOMPSAT-3 satellite images. For objective assessments for change detection, we use F1-score, kappa. We found that the proposed method gives a better performance compared to U-Net and UNet++ by achieving an average F1-score of 0.77, kappa of 77.29.

Single-Channel Seismic Data Processing via Singular Spectrum Analysis (특이 스펙트럼 분석 기반 단일 채널 탄성파 자료처리 연구)

  • Woodon Jeong;Chanhee Lee;Seung-Goo Kang
    • Geophysics and Geophysical Exploration
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    • v.27 no.2
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    • pp.91-107
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    • 2024
  • Single-channel seismic exploration has proven effective in delineating subsurface geological structures using small-scale survey systems. The seismic data acquired through zero- or near-offset methods directly capture subsurface features along the vertical axis, facilitating the construction of corresponding seismic sections. However, substantial noise in single-channel seismic data hampers precise interpretation because of the low signal-to-noise ratio. This study introduces a novel approach that integrate noise reduction and signal enhancement via matrix rank optimization to address this issue. Unlike conventional rank-reduction methods, which retain selected singular values to mitigate random noise, our method optimizes the entire singular value spectrum, thus effectively tackling both random and erratic noises commonly found in environments with low signal-to-noise ratio. Additionally, to enhance the horizontal continuity of seismic events and mitigate signal loss during noise reduction, we introduced an adaptive weighting factor computed from the eigenimage of the seismic section. To access the robustness of the proposed method, we conducted numerical experiments using single-channel Sparker seismic data from the Chukchi Plateau in the Arctic Ocean. The results demonstrated that the seismic sections had significantly improved signal-to-noise ratios and minimal signal loss. These advancements hold promise for enhancing single-channel and high-resolution seismic surveys and aiding in the identification of marine development and submarine geological hazards in domestic coastal areas.

Sensory Information Processing

  • Yoshimoto, Chiyoshi
    • Journal of Biomedical Engineering Research
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    • v.6 no.2
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    • pp.1-8
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    • 1985
  • The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

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