• 운동영양학회지
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• 제16권1호
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• pp.11-17
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• 2012

The purposes of this study were to investigate the effects of acute exercise on blood vaspin, glucose level, and inflammatory cytokines in middle-aged women with pre-diabetes. Nineteen middle-aged women (normal women, n = 11) and women with pre-diabetes(n = 8), who were apparently healthy and not taking any medications affecting their blood pressure or blood glucose, participated. Body fatness parameters including body mass index, body fat percentage, and waist circumference were measured using a bio-impedance analyzer. Resting blood pressure was measured in duplicate, and mean values were used for the data analysis. Regardless of group assignments, all subjects participated in a 3-day consecutive walking exercise at an intensity of 65% VO_2max targeting an energy expenditure of 1200 kcal (400 kcal per day). The major outcome variables included total cholesterol, triglycerides, high-density lipoprotein cholesterol, glucose, vaspin, interleukin-6, and adiponectin levels. Unlike normal women, women with pre-diabetes had a significant improvement in the homeostatic model assessment of insulin resistance (p < 0.025) with no significant group difference in response to acute exercise. The findings suggest that acute exercise results in a significant improvement in insulin sensitivity without any change in serum vaspin levels in women with pre-diabetes.

• 운동영양학회지
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• 제24권1호
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• pp.29-36
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• 2020

[Purpose] The purpose of this study was to investigate the effects of short-term creatine intake on muscle fatigue induced by resistance exercise in healthy adolescent men, i.e., lactic acid concentration and wrist and head tremor measured by an accelerometer. [Methods] Twelve healthy adolescent men who had no experience with creatine intake were included. The subjects were randomly assigned to the creatine group and the placebo group, followed by 5 days of creatine and placebo intake, and 5 times of 5 sets of leg press, leg extension, bench press, and arm curl exercises at 70% repetition maximum (RM). The lactic acid concentration before and after exercising, rate of perceived exertion (RPE), and accelerometer-based wrist tremor and head tremor during exercise were measured. Subsequently, after 7 days to allow for creatine washout, the same exercise treatment and measurement were performed in each group after switching drug and placebo between the groups. [Results] The level of lactic acid before and after the acute resistance exercise trial was significantly lower in the creatine group than in the placebo group (P <0.05). The mean RPE during the resistance exercise was significantly lower in the creatine group than in the placebo group (P <0.05). There was no difference between the two groups in the mean wrist tremor during resistance exercise, but the mean head tremor values were significantly lower in the creatine group than in the placebo group in the arm curl, the last event of the exercise trials (P <0.05). [Conclusion] Short-term creatine intake reduces the blood fatigue factor increased by resistance exercise, and is thought to suppress fatigue, especially in the latter half of resistance exercise. Therefore, these findings indicate that short-term creatine intake can have an improved effect on anaerobic exercise performance.

• Nutrition Research and Practice
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• 제4권4호
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• pp.259-269
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• 2010

Resistance training (RT) is associated with reduced risk of low grade inflammation related diseases, such as cardiovascular disease and type 2 diabetes. The majority of the data studying cytokines and exercise comes from endurance exercise. In contrast, evidence establishing a relationship between RT and inflammation is more limited. This review focuses on the cytokine responses both following an acute bout, and after chronic RT. In addition, the effect of RT on low grade systemic inflammation such as individuals at risk for type 2 diabetes is reviewed. Cytokines are secreted proteins that influence the survival, proliferation, and differentiation of immune cells and other organ systems. Cytokines function as intracellular signals and almost all cells in the body either secrete them or have cytokine receptors. Thus, understanding cytokine role in a specific physiological situation such as a bout of RT can be exceedingly complex. The overall effect of long term RT appears to ameliorate inflammation, but the specific effects on the inflammatory cytokine, tumor necrosis factor alpha are not clear, requiring further research. Furthermore, it is critical to differentiate between chronically and acute Interleukin-6 levels and its sources. The intensity of the RT and the characteristics of the training protocol may exert singular cytokine responses and as a result different adaptations to exercise. More research is needed in the area of RT in healthy populations, specifically sorting out gender and age RT acute responses. More importantly, studies are needed in obese individuals who are at high risk of developing low grade systemic inflammatory related diseases. Assuring adherence to the RT program is essential to get the benefits after overcoming the first acute RT responses. Hence RT could be an effective way to prevent, and delay low grade systemic inflammatory related diseases.

• 한국산림과학회지
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• 제99권1호
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• pp.47-51
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• 2010

본 연구의 목적은 일회성 산림 걷기 운동이 내당능장애(impaired glucose tolerance, IGT)와 인슐린 비의존성 당뇨병(non-insulin-dependent diabetes mellitus, NIDDM)환자의 혈당치 변화에 어떠한 영향을 미치는 가를 알아보기 위한 것이었다. 연구의 대상자는 노인 여성(n=60)을 IGT 산림 걷기 운동군(n=15; $66.21{\pm}4.16$ yrs), NIDDM 산림 걷기 운동군(n=15; $64.85{\pm}3.23$ yrs), IGT 운동장 걷기 운동군(n=15; $67.44{\pm}1.78$ yrs), NIDDM 운동장 걷기 운동군(n=15; $65.55{\pm}8.21$ yrs)으로 구분하여 운동강도 HRmax 50~60%의 산림 걷기 운동(인터벌+저항성 근육운동)과 운동장 걷기 운동(유산소성 운동) 프로그램을 적용하여 운동 전과 후에 혈당을 측정하여 분석하였다. 그 결과, 첫째 내당능장애군에서 산림 걷기와 운동장 걷기 집단은 운동 후에 모두 유의한 수준에서 혈당치의 감소를 보였고, 둘째 인슐린 비의존성 당뇨병군에서 산림 걷기 집단은 운동 후에 혈당치가 유의하게 감소되었지만 운동장 걷기 집단은 특별한 혈당치의 변화가 없었다. 따라서 본 연구는 유산소 운동으로 지속적으로 운동장을 걷는 운동보다 오르막 내리막 지형을 이용한 인터벌 운동과 저항성 근육운동의 복합 형태인 산림 걷기 운동이 내당능장애와 인슐린 비의존성 당뇨병 환자에 더 효과적인 것으로 제안한다.

• 대한물리의학회지
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• 제13권3호
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• pp.141-150
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• 2018

PURPOSE: This study was conducted to understand the adaptive responses of different modes of physical exercises utilizing skeletal muscle and the comprehensive relevance of AMPK signaling that can be activated by physical exercise as a potential molecular target in human health problems such as neuromuscular disorders (NMDs). METHODS: Most of the contents in this review article are based on recent publications concerning the main topics of interest. The reference literatures cited were obtained by basic searches of overseas academic databases such as PubMed and ScienceDirect using EndNote X7.8. RESULTS: The phenotypic adaptive responses of skeletal muscle during endurance- and resistance-based exercise training (ET and RT respectively) appear to be distinct. To explain the adaptive responses in each single mode of exercises (ET, RT) along with combined exercise training (CT), AMPK signaling is proposed as an important molecular link among those differential modes of exercise and a promising molecular target of NMDs. CONCLUSION: Based on the available evidence, intracellular AMPK signaling activated by diverse stimuli including physical exercise can be a potential and promising therapeutic target for the prevention, amelioration or cure of various human health problems including NMDs and may also be beneficial for physical rehabilitation and emergency situations that may elicit acute metabolic stresses.

• 대한물리치료과학회지
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• 제5권4호
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• pp.751-761
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• 1998

The A.M.I(acute myocardiac Infarction) treated in Rehabilitation programs May be divided Into three general types, 1. mechanlcal derangement. 2. Increased resistance to blood flow. 3. decreased Energy production. in each case the heart Will be Limited in its ability to respond. to the demands of metabolic activites. cardiac rehabilitation programs following myocardiac infarction are of two general types:acute and delayed. There are fundamental differences in the philosophies, pathophilogical concepts, and psycosocial values in the two approach. both programs asplre to protect the patient through the period of Maximal risk and then safely restore him to a near normal home life and appropriate vocatlonal activity. Both programs assume that physical activity and emotional stress. increase the work of the heart and with it increase the likefood of venticular fibillation

• 생명과학회지
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• 제24권11호
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• pp.1180-1186
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• 2014

자가포식은 자가포식소체에서 리소좀으로 이어지는 경로를 통해 세포내에서 일어나는 자가분해 시스템으로 다양한 질병과 관련된 운동의 효과를 설명하는데 있어 중요한 역할을 하는 것으로 알려져 있다. 하지만 현재까지 보고된 대부분의 연구는 일회성 운동 혹은 저항성 운동에 의한 자가포식만을 조사한 것으로 일회성 운동과 만성적 운동을 함께 조사한 연구는 전무하다. 따라서 본 연구의 목적은 일회성 및 만성적 유산소운동이 자가포식에 미치는 영향을 알아보는 것이다. White-eyed mutant Drosophila melanogaster를 대상으로 하여 이들을 통제집단, 일회성 운동 집단, 일주일간 하루 2시간 또는 3시간씩 운동을 실시한 집단에 무선배정 하였고, 운동은 일회성 운동과 만성적 운동으로 구성하여 실시하였다. 정량 실시간 연쇄반응을 통해 Atg1, Atg6, Atg8a 유전자의 발현을 관찰한 결과 일회성 운동은 Atg8a mRNA 발현을 유의하게 증가시켰다. 그러나 Atg1, Atg6 mRNA 발현은 일회성 운동으로 유도되지 않았다. 또한 2시간의 만성적 운동에 의해서 Atg6 mRNA 발현이 유의하게 증가되었으나 Atg1, Atg8a mRNA 발현에는 유의한 변화가 나타나지 않았다. 반면 3시간의 만성적 운동을 실시한 결과 Atg1, Atg6, Atg8a mRNA 발현이 각각 57%, 37%, 71%로 모두 유의하게 증가된 것을 관찰할 수 있었다. 본 연구의 결과를 통해서 일회성의 운동은 선별된 자가포식 관련 유전자를 모두 활성화시키지는 못하지만 선택적으로 유도한다는 사실을 확인할 수 있었고, 만성적 운동은 자가포식 관련 유전자의 발현을 증가시킨다는 사실을 확인할 수 있었다. 따라서 본 연구는 일회성 및 만성적 유산소운동이 자가포식에 미치는 영향을 규명하였으며, 자가포식 관련 유전자가 일회성 운동과 만성적 운동에 의해 차별적으로 증가한다는 사실을 확인하였다는데 의의가 있다. 향후 운동에 의한 자가포식 연구에 있어 운동 형태 및 지속시간 등을 고려한 보다 세부적이고 체계적인 연구가 수행될 필요가 있을 것이라 사료되는 바이다.

• 대한통합의학회지
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• 제7권1호
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• pp.113-124
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• 2019

Purpose : The purpose of this study is to investigate the effect of strengthening program for improving the muscle strength and body function in rehabilitation of patients with stroke Methods : We found the 15 precedent studies at online portal site of "Korea education and Research information service" and found 5 precedent studies at "Pubmed". We analyzed and describe the total 19 studies involving national and international research. Results : The strengthening exercise was adapted to lower extremities and trunk muscle of participants and the isokinetic (concentric and eccentric) exercise was most of exercise type and then manual isometric exercise, functional activities, progressive task oriented resistance exercise, PNF pattern exercise was following. The studies reported that the strengthening program increased target muscle strength and improved balance capacity and walking function for the participants positively. Conclusion : Conclusionally the several strengthening program can be the intervention to increase the muscle strength without increasing spasticity for patients with stroke. We think that the strengthening of lower extremities an improve balance capacity and walking ability and it can use the intervention to change the quality of life in patients with stroke. More than 3weeks strength program might be effectiveness, in case of acute patients with stroke, the improving of muscle strength is available but need to study for improving balance and walking capacity more in the future.

• 한국산학기술학회논문지
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• 제13권3호
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• pp.1194-1202
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• 2012

최근에 발견된 Adiponectiin과 gut hormone은 지질대사와 인슐린 저항성, 그리고 식욕에 영향을 주는 것으로 보고되고 있다. 이 연구의 목적은 장기간 트레이닝을 한 고등학교 씨름선수 16명(경량급=8, 장사급=8)을 대상으로 일시적 운동을 실시하여, 운동 전 후의 혈중 Adiponectin과 Gut hormones 농도의 변화와 체중차이에 의한 농도에 차이가 있는지를 구명하고 체중의 차이가 운동의 효과에 어떠한 영향을 미치는지를 구명하고자 하였다. 실험방법으로 일시적 운동프로그램은 40분간 걷기를 한 후, 5분간 all-out 달리기를 실시하였으며 운동 전 후에 혈액을 채혈하여 분석하였다. 이 연구의 결과에서 Adiponectin과 Ghrelin의 농도는 경량급선수가 장사급선수보다 유의하게 높은 것으로 나타났으며(p<.05), 인슐린의 농도에서는 반대로 장사급선수가 경량급선수보다 유의하게 높은 것으로 나타났다(p<.01). 또한, 운동 전 후의 유의한 차이는 오직 글루카곤에서 운동 후에 유의하게 증가하였으며(p<.01), 다른 모든 변인에서 운동 전 후의 유의한 차이는 나타나지 않았다. 이 연구의 결과에서는 Adiponectin과 인슐린, Ghrelin 등의 혈중 농도에 대한 일시적인 운동 효과는 없었으며 체중 차이에 의해서 변화를 보였고, 글루카곤의 경우에만 일시적인 운동에 영향을 받아 증가되는 것으로 나타났다. 따라서 Adiponectin과 인슐린, Ghrelin 등의 농도는 지속적인 운동의 효과와 체중 차이에 영향을 받는 것으로 생각되며 글루카곤은 일시적인 운동에도 효과가 있는 것으로 사료된다.

• 운동영양학회지
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• 제24권2호
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• pp.6-10
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• 2020

[Purpose] Milk is a commonly ingested post-exercise recovery protein source. Casein protein, found in milk, is characterized by its slow digestion and absorption. Recently, several studies have been conducted with a focus on how pre-sleep casein protein intake could affect post-exercise recovery but our knowledge of the subject remains limited. This review aimed at presenting and discussing how pre-sleep casein protein ingestion affects post-exercise recovery and the details of its potential effector mechanisms. [Methods] We systematically reviewed the topics of 1) casein nutritional characteristics, 2) pre-sleep casein protein effects on post-exercise recovery, and 3) potential effector mechanisms of pre-sleep casein protein on post-exercise recovery, based on the currently available published studies on pre-sleep casein protein ingestion. [Results] Studies have shown that pre-sleep casein protein ingestion (timing: 30 minutes before sleep, amount of casein protein ingested: 40-48 g) could help post-exercise recovery and positively affect acute protein metabolism and exercise performance. In addition, studies have suggested that repeated pre-sleep casein protein ingestion for post-exercise recovery over a long period might also result in chronic effects that optimize intramuscular physiological adaptation (muscle strength and muscle hypertrophy). The potential mechanisms of pre-sleep casein protein ingestion that contribute to these effects include the following: 1) significantly increasing plasma amino acid availability during sleep, thereby increasing protein synthesis, inhibiting protein breakdown, and achieving a positive protein balance; and 2) weakening exercise-induced muscle damage or inflammatory responses, causing reduced muscle soreness. Future studies should focus on completely elucidating these potential mechanisms. [Conclusion] In conclusion, post-exercise ingestion of at least 40 g of casein protein, approximately 30 minutes before sleep and after a bout of resistance exercise in the evening, might be an effective nutritional intervention to facilitate muscle recovery.