• Title/Summary/Keyword: activity.

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Physiological Activity of Extracts of Bark from Ulmus davidiana var. japonica and its fractions (유근피 추출물 및 분획의 생리활성)

  • Yang, Sun a;Kim, A young;Pyo, Byoung sik;Kim, Sun min
    • Korean Journal of Pharmacognosy
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    • v.50 no.2
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    • pp.112-117
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    • 2019
  • In this study, extracts of bark from Ulmus davidiana var. japonica and its fractions were investigated the antioxidative, antibacterial and tyrosinase inhibition activity for physiological activity towards functional applications. In the measurement of DPPH radical scavenging activity, the ethyl acetate fraction showed higher radical scavenging ability than others. Moreover, in the tyrosinase inhibition assay, showed that the ethyl acetate fraction has good inhibition effects. Results of the DPPH radical scavenging and tyrosinase inhibition activity are related with the total polyphenol concentrations of ethyl acetate fraction. In antibacterial activity used to find out by utilizing the disc diffusion assay, chloroform fraction showed strong effect against Staphylococcus aureus and S. epidermidis. These results are related with the flavonoid contents of chloroform fraction. On the other hand, in the L929 cell viability measurement by MTT assay, the hexane, butanol and aqueous fraction treated at high concentration were showed cytotoxicity. But the others samples were exhibited a moderate viabilities. As a result of investigated the antioxidant and tyrosinase inhibition activity, the ethyl acetate fraction could be applicable for cosmetics related fields. And the chloroform fraction showed significant antibacterial activity against S. aureus and S. epidermidis.

Study on Bioactive Materials Using By-Products of Alcohol Fermentation (Tapioca-Unhulled Barley Dried Distiller's Grains) (알코올 발효 부산물(타피오카 · 겉보리 주정박) 활용한 생리활성 및 기능성 소재연구)

  • Eun-Jeong Jeong
    • Journal of the Korean Society of Industry Convergence
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    • v.26 no.1
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    • pp.47-57
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    • 2023
  • In this study, the bioactive activities (antioxidant activity, whitening activity, and anti-wrinkle effect) of dried tapioca-unhulled barley grain residue (TUDDG) obtained after alcohol fermentation, were measured. In the case of DPPH radical scavenging activity, the 50% ethanol extract of TUDDG showed the highest level of about 83% at the concentration of 100 mg/ml, and the ABTS radical scavenging activity was also about 98% of the 50% ethanol extract of TUDDG even at the concentration of 10 mg/mL. In the case of mushroom tyrosinase inhibitory activity, the 50% ethanol extract of TUDDG showed the highest activity at 100 mg/ml concentration of 37%. As a result of collagenage activity inhibition and elastase analysis, the 50% ethanol extract of TUDDG showed high activity with 4.2 mg/mL (IC50) and 26.1 mg/mL (IC50), respectively. Therefore, considering the physiological activity as well as the extraction efficiency of physiologically active substances, the 50% ethanol extract of TUDDG is judged to be highly effective.

Characterization of antioxidant and anti-inflammatory activities in the grains of collected Sorghum bicolor varieties

  • Ji Won Seo;Jae Geun Lee;Bimal Kumar Ghimire;Myong Jo Kim;Chang Yeon Yu;Eun Soo Seong
    • Journal of Applied Biological Chemistry
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    • v.66
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    • pp.227-235
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    • 2023
  • The current study evaluated the presence and concentration of health-promoting phenolic antioxidants in sorghum seed accessions from seven regions in three different countries (Uzbekistan, Myanmar, and the United States). The free radical scavenging activity using the 2,2-diphenyl-1-picrylhydrazyl assay was 13.10±2.37 ㎍/mL in the Uzbekistan sorghum seed extracts, demonstrating the highest antioxidant activity. Additionally, the total phenol content was the highest in the Uzbekistan sorghum seed extracts [157.87±4.04 mg GAE/g (gallic acid equivalents per gram)]. The total flavonoid content was 12.69±0.72 mg QE/g (quercetin equivalents per gram) and represents the highest value in the Myanmar collection. The Uzbekistan collection demonstrated the greatest potential for whitening activity, with the tyrosinase inhibition rate of 79.20±4.15%. The wrinkle improvement function using elastase also showed the highest anti-aging activity of 55.85±4.78% in the same seed extract. The Uzbekistan seed extract had the highest NO production inhibitory activity of 144.35±4.55%. We conclude from these results that the Uzbekistan sorghum seed has excellent antioxidant activity, content of various functional ingredients, and anti-inflammatory activity.

Carbohydrate, Lipid Inhibitory Activity and Antioxidant Activity of Extracts from Several Economic Resource Plants in Vitro

  • Boo, Hee-Ock;Shin, Jeoung-Hwa;Choung, Eui-Su;Bang, Mi-Ae;Choi, Kyung-Min;Song, Won-Seob
    • Korean Journal of Plant Resources
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    • v.26 no.3
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    • pp.374-382
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    • 2013
  • The objective of this study was determined to evaluate ${\alpha}$-amylase, ${\alpha}$-glucosidase, pancreatic lipase inhibition in vitro and DPPH radical scavenging activity of the several Korean resources plants. The ${\alpha}$-amylase inhibitory activity of Salicornia herbacea, Erythronium japonicum (flower) and Phragmites communis (root) in water extract showed relatively high 62.8%, 66.5% and 69.3%, respectively. The ${\alpha}$-amylase inhibitory activity of Citrus junos (pericarp) and Cornus officinalis in methanol extract was found to have an effect with 32.8% in Citrus junos (pericarp) and 60.9% in Cornus officinalis. Corylopsis coreana in both water and methanol extract had the highest ${\alpha}$-glucosidase inhibitory activity of 81.7% and 89.5%, while the extract of Portulaca oleracea, Ficus carica and Citrus junos was not measured ${\alpha}$-glucosidase inhibitory activity at given experiment concentration. Depending on the extraction solvent and the plant species, it was observed that there was a significant difference in ${\alpha}$-glucosidase inhibitory activity. The pancreatic lipase inhibitory activity showed relatively higher in the methanol extract than water extract except pericarp of Citrus junos. The DPPH radical scavenging activity of selected plants was much difference between measured plant species, and showed that the increase was proportional to the concentration. These results suggested that selected plants had the potent biological activity on carbohydrate, lipid Inhibitory activity and antioxidant activity, therefore these plant resources could be a good materials to develop medicinal preparations, nutraceuticals or health functional foods for diabetes or obesity.

Relation of Physical Activity and Visceral Adipose Tissue Accumulation in Korean Obese and Overweight Women (한국 비만 및 과체중 여성에서 내장 지방과 신체 활동 사이의 연관성)

  • Cho, Yu-Jeong;Lee, A-Ra;Hwang, Mi-Ja;Chung, Won-Suk;Song, Mi-Yeon
    • Journal of Korean Medicine for Obesity Research
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    • v.8 no.2
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    • pp.49-62
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    • 2008
  • Objectives Physical activity is known to be beneficial to prevent weight gain and to be physically healthy. In this study, we tried to find out the relationship between body composition with physical activity. Methods International Physical Activity Questionnaire(IPAQ)-short form was given to premenopausal women aged 20~55 and BMI${\geq}23\;kg/m^2$. Subcutaneous and visceral adipose tissue of the subjects by CT scanning was obtainedin a single slice. They were given written consent and this study is performed under the permission of institutional review board of Kyung Hee East-west Neo Medical Center. Results The mean of physical activity of total subjects was 1935.18 MET-min/week(n=63). When three groups of physical activity pattern(inactive, minimally active, and HEPA(Health-enhancing physical activity) active) was analyzed, all of them were heavily relied on the activity intensities of walking. The VSR(visceral/Subcutaneous adipose tissue Ratio) was correlated with total physical activity in vigorous activity group. Conclusions The physical activity of Korean obese and overweight women was on the average, but the vigorous activity is thought to be necessary. The vigorous physical activity was related with visceral adipose tissue.

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Fear of Falling, Depression, Physical Fitness and Physical Activity among Community Dwelling Elders (지역사회 노인의 신체활동도와 낙상 두려움, 우울, 신체기능)

  • Lee, Young-Hee;Choi, Mi-Kyoung
    • Korean Journal of Adult Nursing
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    • v.23 no.4
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    • pp.351-362
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    • 2011
  • Purpose: This study was designed to examine fear of falling, depression, physical fitness, and physical activity and further to identify the factors that predict physical activity among community dwelling elders. Methods: This study was a cross-sectional descriptive survey. Participants were 153 community dwelling elders from G city. Data were collected using structured questionnaires and were analyzed using descriptive statistics, ${\chi}^2$-test, t-test, ANOVA, and multinominal logistic regression analysis. Results: Activity levers were coded as inactive, minimal activity and enhancing physical active. Thirty-three point three percent reported inactivity, forty-seven point seven percent reported minimal activity and nineteen percent reported health enhancing physical activity. There were significant differences in physical activity relative to gender, age, falling experience, perceived health, and living situation. Further, there was significant difference in fear of falling, depression, and physical fitness by physical activity. For instance, Fear of falling (OR=1.04, p=.014) was a significant predicting factor for physical activity, In contrast for the enhancing physical active the variables of gender (OR=0.28, p=.046), age (OR=0.86, p=.021), perceived health (fair: OR=13.61, p=.006), fear of falling (OR=1.04, p=.026), and two-minute step (OR=1.04, p=.049) were significant. Conclusion: The results of this study indicate that physical activity intervention programs are needed to increase physical activity for community dwelling elders. Physical activity intervention programs should be developed and evaluated.

Antimicrobial Activity on Respiration Diseases Inducing Bacteria and Antioxidant Activity of Water Extracts from Wild Edible Vegetables (산채류 추출물의 항산화 활성 및 호흡기 질환을 유발하는 세균에 대한 항균활성)

  • Lee, In-Soon;Moon, Hae-Yeon
    • KSBB Journal
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    • v.27 no.2
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    • pp.114-120
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    • 2012
  • To investigate the antimicrobial activity on bacteria causing a respiration disease and antioxidant effects of water extracts from 12 kinds of wild edible vegetables, we extracted the water extracts for 72 h in $7^{\circ}C$ using distilled water as solvent. The water extracts except Ixeris dentate and Allium monanthum had high concentrations of phenol compounds and flavonoids. Liguraia fischeri specially had the highest level on total phenol compounds and flavonoids with 205 ${\mu}g/mL$ and 98. 86 ${\mu}g/mL$, respectively. The each 0.05% extracts of Sedum sarmentosum and Liguraia fischeri had high effect on the DPPH radical scavenging activity among wild edible vegetables and the most extracts promoted antioxidant activity with increasing concentration of extract. The catalase activity of Erysimum aurantiacum and Aralia elata showed more than 150 units per g of fresh tissue. The effect of antimicrobial activity on water extracts showed characteristic activity. Only Staphylococcus aureus KCTC 1928 and Corynebacterium diptheriae KCTC 3075 were inhibited cell growth on the other hands, the remainder of bacteria was not inhibited cell growth. Nevertheless, the extracts of wild edible vegetables had specific concentration as MIC for antimicrobial activity respectively. In case of the extract of Aster scaber, Erysimum aurantiacum, and Allium monanthum had over 30% antimicrobial activity on the bacteria causing a respiration disease. In results, the wild edible vegetables include high concentrations of total phenol compounds and flavonoids that give a good antioxidant activity and antimicrobial activity. Therefore the wild edible vegetables are functional food for anti-aging and physiological activation.

Related Factors of Physical Activity in Rural Elderly Chronic Disease (농촌 만성질환 노인의 신체활동관련 요인)

  • Peak, Hyun-Hee;Kim, Jeong-Ja
    • Journal of Korean Clinical Health Science
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    • v.2 no.4
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    • pp.247-255
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    • 2014
  • Purpose. This study is based on physical and mental health and physical activity differences in Practice rate each physical activity according to the body to target the 319 people who live in rural areas of 65 and older who have chronic diseases Practice rate activities, general characteristics of chronic diseases, elderly differences in physical activity and investigate the factors that influence. Methods. Physical activity Practice rate was used for descriptive statistics. Each physical activity Practice rate in accordance with the general characteristics of the rural elderly chronic disease were independent T test and One-way ANOVA test. To evaluate the factors influencing the physical activity was the multiple logistic regression analysis. Results. Results of physical activity practice was the most flexibility exercise was walking then, Practice rate each physical activity in accordance with the general characteristics of the elderly are tangible and physical activity radish age, housing type, education level, health insurance part statistically significant were different. Physical health status according to the presence or absence of physical activity showed a significant difference in daily life activities and limited mental health differences were not significant. Factors affecting the physical activity of the elderly with chronic diseases appeared to limit the presence and activities of daily living. Conclusions. As well there is no activity restrictions can be more physically active everyday life well. It is suggested that it is important to approach everyday life, I can help eliminate the factors that independently giving limits on the activities of the elderly with chronic diseases.

Indoor Physical Activity Reduces All-Cause and Cardiovascular Disease Mortality Among Elderly Women

  • Park, So-Young;Lee, Joong-Yub;Kang, Dong-Yoon;Rhee, Chul-Woo;Park, Byung-Joo
    • Journal of Preventive Medicine and Public Health
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    • v.45 no.1
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    • pp.21-28
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    • 2012
  • Objectives: The aim of this study was to investigate whether a medium to high degree of total physical activity and indoor physical activity were associated with reduced all-cause and cardiovascular mortality among elderly Korean women. Methods: A prospective cohort study was done to evaluate the association between physical activity and mortality. The cohort was made up of elderly (${\geq}65$ years of age) subjects. Baseline information was collected with a self-administered questionnaire and linked to death certificates retrieved from a database. Cox proportional hazard models were used to estimate the hazard ratios (HRs) with 95% confidence interval (CI) levels. Results: Women who did not suffer from stroke, cancer, or ischemic heart disease were followed for a median of 8 years (n=5079). A total of 1798 all-cause deaths were recorded, of which 607 (33.8%) were due to cardiovascular disease. The group with the highest level of total physical activity and indoor physical activity was significantly associated to a reduced all-cause mortality (HR, 0.60; 95% CI, 0.51 to 0.71 and HR, 0.58; 95% CI, 0.50 to 0.67, respectively) compared to the group with the lowest level of total physical activity and indoor physical activity. Additionally, the group with the highest level of total physical activity and indoor physical activity was significantly associated to a lower cardiovascular disease mortality (HR, 0.53; 95% CI, 0.40 to 0.71 and HR, 0.51; 95% CI, 0.39 to 0.67, respectively) compared to the group with the lowest level of total physical activity and indoor physical activity. Conclusions: Our study showed that regular indoor physical activity among elderly Korean women has healthy benefits.

Analysis of Youth Center Programs Based on the Domains for Creative Activity (창의적 체험활동 영역별 경남지역 청소년 수련시설 프로그램의 분석)

  • Choi, Byung-Ok
    • Journal of Fisheries and Marine Sciences Education
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    • v.24 no.4
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    • pp.516-527
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    • 2012
  • This study analyzed the programs offered in the youth center located in Gyeongsangnam-do Province in accordance with the domains for creative activity. The creative activity, introduced through the 2009 revised national curriculum, puts an emphasis on the experiential activities to enhance the creativity of students. The creativity activity needs to be operated as intended in order to ensure that the students can grow into adults, who have creativity and good personality, by amassing a variety of experiences. For that, various human resources and physical resources of communities need to be utilized efficiently. Thus, this study explored the measures to achieve the original objectives of creativity activity by analyzing the programs - offered by the youth centers in Gyeongsangnam-do Province - based on the scope of creativity activity. The followings are the results of the analysis of 177 programs offered in 12 organizations that came under the three categories (training facilities operated directly by the Education Office, public training centers, culture center) of the youth centers located in Gyeongsangnam-do Province. Autonomous activity' comprised the highest proportion in the youth center programs of the three categories, followed by club activity. The programs associated with the 'career activity' - which most students have the highest expectations in relation to the creativity activity - comprised relatively low proportion. In conclusion, the programs offered by the youth centers in communities need to become more diversified in order to achieve the intended results of creative activity. In addition, the programs associated with the 'career activity', which student prefer the most, need to be operated in a more diversified manner with greater emphasis. Furthermore, the measures should be explored which may increase the involvement of youth education experts of community in the operations of creativity activity.