• Physical Therapy Rehabilitation Science
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• 제11권4호
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• pp.571-578
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• 2022

Objective: Cognitive-motor trainings had a positive impact on cognitive function and dual-task trainings led to improvements of global cognitive function. The brain activity of the prefrontal cortex (PFC) is another indicator that can infer cognitive function. This study aims to confirm the usability of the interactive system cognitive-motor training program and the changes in the prefrontal cortex through training. Design: Cross-sectional study Methods: In this study, two cognitive tasks were randomly applied to 20 adults as cognitive-motor training using an interactive system, and the same task was performed using the original method. During all tasks, the brain activity of the prefrontal cortex was measured by the change in oxyhemoglobin (HbO) in real-time using Functional Near-Infrastructure. After performing the tasks, the usability of the developed interactive system was evaluated by a usability questionnaire which consists of five items, and each item consists of a 7-point Likert scale that responds from 1 point to 7 points. Results: The HbO levels were increased during cognitive task performance than at the resting phase. And evaluating the usefulness of the interactive system, a questionnaire result showed that it would be useful for cognitive-motor programs. Conclusions: The cognitive-motor training using the interactive system increased the activity of the prefrontal cortex, and the developed wearable sensor-based interactive system confirmed its usefulness.

• The Korean Journal of Physiology and Pharmacology
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• 제9권1호
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• pp.63-68
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• 2005

Hydrogen peroxide ($H_2O_2$) causes oxidative stress and is considered as an inducer of cell death in various tissues. Two-pore domain $K^+$ ($K_{2p}$) channels may mediate $K^+$ efflux during apoptotic volume decreases (AVD) in zygotes and in mouse embryos. In the present study, we sought to elucidate linkage between $K_{2p}$ channels and cell death by $H_2O_2$. Thus $K_{2p}$ channels (TASK-1, TASK-3, TREK-1, TREK-2) were stably transfected in HEK-293 cells, and cytotoxicity assay was preformed using cell counting kit-8 (CCK-8). Cell survival rates were calculated using the cytotoxicity assay data and dose-response curve was fitted to the $H_2O_2$ concentration. Ionic currents were recorded in cell-attached mode. The bath solution was the normal Ringer solution and the pipette solution was high $K^+$ solution. In HEK-293 cells expressing TREK-1, TREK-2, TASK-3, $H_2O_2$ induced cell death did not change in comparison to non-transfected HEK-293. In HEK-293 cells expressing TASK-1, however, dose-response curve was significantly shifted to the left. It means that $H_2O_2$ induced cell death was increased. In cell attached-mode recording, application of $H_2O_2$ (300μM) increased activity of all $K_{2p}$ channels. However, a low concentration of $H_2O_2$ ($50{\mu}M$) increased only TASK-1 channel activity. These results indicate that TASK-1 might participate in $K^+$ efflux by $H_2O_2$ at low concentration, thereby inducing AVD.

• Physical Therapy Rehabilitation Science
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• 제1권1호
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• pp.1-5
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• 2012

Objective: Dual-task walking deficits impact functional daily life, which often requires walking while performing simultaneous tasks such as talking, thinking or carrying an object. This study is to find out the latest trend of dual-task training's influence on ambulatory abilities of a stroke patient. Design: Systematic review of randomized controlled trials. Methods: This literature review was conducted in Pubmed and Sciencedirect with the follwing key words:stroke, cerebro-vascular accident, hemiplegia, gait, rehabilitation, exercise. 7 studies were chosen in findings by search tool. 3 studies were case study, 3 studies were cross sectional observational study and 1 study was randomized controlled trial. Results: It was found that stroke patients have difficulties in doing 2 motor tasks simultaneously and when they do 2 tasks, one is done in a naturally preferred activity areas. Moreover, when simply applying dual-tasks, the walking speed decreased. Meanwhile, when applying them through training, the speed increased. This showed the improvement of effective task-implementation abilities after dual-task training using task-integration models. Conclusions: In the beginning of the 2000s, dual-tasks were implemented by simply combining walking and cognition or exercise task, and the results of this study suggest that subjects with stroke have difficulty performing dual task. However, the latest trend is to let patients do the dual-task training by combining it with virtual reality. Therefore, dual task training could be performed in a safe in the environment such as virtual reality or augment reality.

• 한국산학기술학회논문지
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• 제16권2호
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• pp.1153-1163
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• 2015

본 연구는 수부손상환자를 대상으로 과제 지향적 활동이 손 기능에 미치는 효과를 알아보고자 하였다. 2011년 12월부터 2012년 10월까지 경남 창원에 위치하는 C병원에 내원한 16명의 수부손상환자를 두 그룹으로 무작위 할당한 후 실험군에 과제 지향적 활동을 1일 1회, 주 3회, 4주 동안 적용하고 그룹 간 비교를 실시하였다. 과제 지향적 활동군은 캐나다 작업수행측정(Canadian Occupational Performance Measure; COPM)을 통해 대상자가 선호하는 일상생활활동영역에 대한 과제를 제공하였다. 이때 중재의 효과를 검증하기 위해 손 기능 평가로 장악력 검사, 파악력 검사, 엄지의 맞섬, 손가락의 벌림 범위와, Purdue pegboard test, Disabilities of the Arm, Shoulder, and Hand(DASH)를 사용하였다. 중재 전후 비교에서 과제 지향적활동군은 모든 손 기능 평가에 유의하게 향상되었고(p<.05), 대조군의 손 기능도 유의하게 향상되었다(p<.05). 그룹 간 비교에서 과제 지향적 활동군은 손끝집기, 측면집기, 세점집기, Purdue pegboard test, DASH에서 대조군과 유의한 차이가 있었으나(p<.05), 장악력 검사와 엄지의 맞섬 및 손가락의 벌림 범위는 그룹 간 유의한 차이가 없었다. 본 연구의 결과를 통해 과제지향적 활동이 수부손상환자의 손 기능 향상에 더 효과적임을 알 수 있었다.

• 과학교육연구지
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• 제46권1호
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• pp.30-39
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• 2022

이 연구의 목적은 중등학생의 자기조절 과정에서 동화, 갈등, 조절의 세부 과정에 대한 뇌 활성을 비교하고 분석하는 것이다. 자기조절 과제는 생물학적 계통발생 과제로 제시되었고, 뇌활성은 fNIRS로 측정 및 분석되었다. 그 결과 동화 과정과 비교하여 갈등 과정에서 좌측 DLPFC, OFC, FP 영역에서 유의미한 활성이 발견되었고, 조절 과정에서는 DLPFC, VLPFC에서 유의미한 활성화가 발견되었다. 중등학생의 학년이 높아질수록 갈등 과정에서도 DLPFC가 증가하고 동화 과정에서도 VLPFC가 증가한다. 또한, 갈등과 조절 과정을 비교한 결과, 7학년 학생들은 오른쪽 VLPFC에서 유의미한 뇌 활동을 보였고, 9학년 학생들은 조절 과정에서 왼쪽 FP와 DLPFC 영역에서 유의미한 뇌 활동을 보였지만, 11학년 학생들은 이 과정에서 유의미한 뇌 활동을 보이지 않았다. 이러한 결과는 신경학적 연구 방법이 인지 활동과 강의실 교육 상황과 관련된 교육 연구에 적용될 수 있음을 보여준다.

• 한국비블리아학회지
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• 제32권4호
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• pp.89-109
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• 2021

본 연구는 대학도서관 전자책 서비스 담당자의 업무 활동과 업무 수행의 어려운 점을 분석하여 서비스 업무 개선에 필요한 기초자료를 제시하고자 하였다. 이를 위해 학술정보통계시스템을 참고하여 전자책 보유 종수가 많은 대학의 전자책 서비스 담당자 9명을 대상으로 반구조화된 면담을 실시하였고, 수집한 자료는 활동이론을 적용하여 분석하였다. 연구 결과, 담당자들은 전자책 서비스 목표를 달성하기 위해 다양한 도구를 활용하고 있었으며, 교내외의 여러 구성원들과 소통하고 있었다. 또한 각 구성원들의 분업을 통해 서비스 업무가 지속되고 있었으며, 전자책 서비스 업무 활동과 관련한 교내 및 교외 수준의 규칙이 존재했다. 그러나 업무 활동 과정에서 예산 부족, 국내 전자책의 상이한 제작 방식과 이로 인한 이용의 불편함, 일부 구성원과의 의견 충돌 등의 갈등이 파악되었다. 나아가 담당자들이 언급한 전자책 서비스 개선방안을 콘텐츠 측면, 시스템 측면, 정책적 측면으로 구분하여 제시하였다.

• PNF and Movement
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• 제20권1호
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• pp.135-145
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• 2022

Purpose: The purpose of this study was to investigate the association between cognitive and motor inhibition by comparing muscle activity and ground reaction force during unplanned gait termination according to reaction time measured through the stop-signal task. Methods: Sixteen young adults performed a stop-signal task and an unplanned gait termination separately. The subjects were divided into fast and slow groups based on their stop-signal reaction time (SSRT), as measured by the stop-signal task. Electromyography (EMG) and ground reaction force (GRF) were compared between the groups during unplanned gait termination. The data for gait termination were divided into three phases (Phase 1 to 3). The Mann-Whitney U test was used to compare spatiotemporal gait parameters and EMG and GRF data between groups. Results: The slow group had significantly higher activity of the tibialis anterior in Phase 2 and Phase 3 than the fast group (p <0.05). In Phase 1, the fast group had significantly shorter time to peak amplitude (TPA) of the soleus than the slow group (p <0.05). In Phase 2, the TPA of the tibialis anterior was significantly lower in the fast group than the slow group (p <0.05). In Phase 3, there was no significant difference in the GRF between the two groups (p >0.05). There were no significant difference between the two groups in the spatiotemporal gait parameters (p >0.05). Conclusion: Compared to the slow group, the fast group with cognitive inhibition suppressed muscle activity for unplanned gait termination. The association between SSRT and unplanned gait termination shows that a participant's ability to suppress an incipient finger response is relevant to their ability to construct a corrective gait pattern in a choice-demanding environment.

• The Journal of Korean Physical Therapy
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• 제27권5호
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• pp.325-331
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• 2015

Purpose: This study attempts to understand the effect of stabilization exercise of biofeedback scapular on muscle activity and functional evaluation of the upper extremity in stroke patients. Methods: Patients were divided into two groups; a biofeedback scapular stabilization exercise group comprised of 8 patients and a task-oriented training group including another 8 patients, and 30-minute exercise was performed 5 times a week for 8 weeks. Electromyogram was used to measure muscular activity of lower trapezius, deltoid middle, and serratus anterior. Fugl-Meyer Assessment and Manual Function Test were used to evaluate functions of the muscles mentioned. Results: Significant difference was observed in the comparison group before and after exercise in muscular activity of lower trapezius, deltoid middle, and serratus anterior, Fugl-Meyer Assessment, and Manual Function Test. Conclusion: Therefore, we could see that biofeedback scapular stabilization exercise is more effective than task-oriented training in facilitating muscle activation and functional capacity of upper limb.

• 대한물리의학회지
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• 제6권4호
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• pp.465-473
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• 2011

Purpose : This study was to evaluate gait velocity and muscle activity on 3 different gait conditions in elderly women. Methods : There were one group was 20's generation(n=12), and the other group was over 60's generation (n=12). The velocity of gait was analysed for using the Footscan system, EMG(MP150) for muscle activity. Subjects were measured 3 gait condition(normal, obstacle-10cm, dual obstacle-10cm. Measured values were used by the independent t-test for analysing between groups, and repeated measurement of ANOVA for analysing within group. Results : The results were as follow: velocity and acticities of lower 4 muscles were significantly differences in experimental group. In control group, there were not significantly differences. Contrast-groups were significantly differences of velocity(obstacle, dual obstacle), muscle activities(soleus-dual obstacle, hamstring-all). Conclusion : These results indicate that elderly people are reduced gait ability in dual task, and obstacle gait. So Elderly women need to training obstacle/dual gait for preventing falling.

• 수도
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• 통권70호
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• pp.15-21
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• 1994