• Applied Microscopy
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• 제19권1호
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• pp.27-33
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• 1989

Six cases of ovarian fibrous stromal neoplasm were studied clinically, light microscopically and ultrastructurally for the clinico-pathological evidences of hormone production. Of the six cases, two cases were fibroma, three cases were fibrothecoma, and one case was thecoma. Two cases of fibroma and one fibrothecoma were associated with clinical history of menstrual abnormality, however fat staining of the tumor was negative or weakly positive. Two cases of fibrothecoma and one thecoma were negative for the clinical history of hormone imbalance. Fat stain of those cases revealed positive in varying intensity. Ultrastructural examination of fibroma-thecoma group revealed dark and pale cells by their nuclear characteristics. The dark cells had indented nucleus and abundant cytoplasmic organelles of rough ER, Golgi apparatus and mitochondria. Intracytoplasmic cisternal spaces were seen in the dark cell cytoplasm and some lipid droplets were seen around the cisternae. Pale cells had pale swollen nucleus and fine chromatins. Their cytoplasm showed scanty amount of organelles. Fibroma-thecoma spectrum showed varying degree of population of dark cells, light cells and intervening collagenous stroma. Lipid droplet was structurally associated with intracytoplasmic cisterna and they were frequently seen in thecoma and two of the fibrothecoma. But clinical history of hormone imbalance was poorly related to the light microscopic morphology and ultrastructural organization.

• Journal of Ecology and Environment
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• 제33권1호
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• pp.3-13
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• 2010

The Tsushima leopard cat, Prionailurus bengalensis euptilurus, a small felid, inhabits only the Tsushima Islands in Japan. Previous studies of the Tsushima leopard cat revealed that natural factors; including sex, reproductive activity, season, and prey distribution and abundance affect leopard cat home range variation and habitat use. In this study, we focused on clarifying how anthropogenic factors influenced home range variation and habitat use of a male Tsushima leopard cat living near a suburban area in January, March, May and September 2005 using radio-tracking. The home range size (100% MCP) of this cat was $0.78\;{\pm}\;0.26\;km^2$ (mean ${\pm}$ SD, n = 4 tracking sessions) across the whole study period. However, the cat did not use all parts of its home range uniformly; rather it used some habitat types selectively. The cat avoided agriculture areas and residential areas in all of the tracking-sessions. On the other hand, the cat showed a weak preference for artificial structures and a strong preference for baiting sites in January and March, while it avoided them in May, and no baiting site was included in its home range in September. These results suggest that anthropogenic factors influenced the ranging patterns and habitat use of the leopard cat living near a suburban area. Artificial structures might provided good resting spaces for the cat in bad weather. When the density of its main prey was low in the winter, the cat tended to rely on artificial prey and had a small home range size.

• 한국실내디자인학회논문집
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• 제19권6호
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• pp.224-232
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• 2010

This paper aims to identify the characteristics and the current situation of the architectural characteristics, children's characters using facilities, and status of management and utilization by surveying 'Day Service for Children' in Tokyo-do. First, About the status of management and utilization, 'Day Service for Children' is operated by a local government, NPO corporate group and social welfare corporate. There are not big differences of the care program or running hours depending on operating principals but there are differences depending on staff organization, number of children and space constitution. Also, infants ratio at 'Day Service for Children' is high for the purpose of detecting disability early and supporting their development early. They have diverse disabilities but developmental disabilities' ratios high and most children are using both this facility and normal nursery centers together. Samples for proper child care based on status of space constitutions were installing lock, raising door knobs and using softer floor materials which are for children's safety. For the problem of space utilization, most comments were about lack of space which is not enough for teaching and training materials. Therefore, as an example, observation rooms for parents and teachers were sometimes used as storages and it changes teachers' moving direction, staying area and behavior zone. The programs of 'Day Service for Children' are divided to group teaching and private one. It will be the best if they have separate spaces such as group class room, private class room and play room. When they were operated by NPO corporate group or Social welfare corporate, there are many cases that their space was not properly zoned for each activity.

• Toxicological Research
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• 제26권3호
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• pp.217-222
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• 2010

Many studies have reported that bleomycin, anti-cancer drug, induces pulmonary fibrosis as a side effect. However, few investigations have focused on the dose-response effects of bleomycin on pulmonary fibrosis. Therefore, in the present study, we investigated the effects of different doses of bleomycin in male mice. ICR mice were given 3 consecutive doses of bleomycin: 1, 2, or 4 mg/kg in bleomycin-treated (BT) groups and saline only in vehicle control (VC) groups. The animals were sacrificed at 7 and 24 days postinstillation. The severity of pulmonary fibrosis was evaluated according to inflammatory cell count and lactate dehydrogenase (LDH) activity in the broncho alveolar lavage fluid (BALF), and lung tissues were histologically evaluated after hematoxylin and eosin (H&E), and Masson's trichrome staining. BT groups exhibited changed cellular profiles in BAL fluid compared to the VC group, which had an increased number of total cells, neutrophils, and lymphocytes and a modest increase in the number of macrophages at 7 days post-bleomycin instillation. Moreover, BT groups showed a dose-dependent increase in LDH levels and inflammatory cell counts. However, at 24 days after treatment, collagen deposition, interstitial thickening, and granulomatous lesions were observed in the alveolar spaces in addition to a decrease in inflammatory cells. These results indicate that pulmonary fibrosis induced by 4 mg/kg bleomycin was more severe than that induced by 1 or 2 mg/kg. These data will be utilized in experimental animal models and as basic data to evaluate therapeutic candidates through non-invasive monitoring using the pulmonary fibrosis mouse model established in this study.

• 정보교육학회논문지
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• 제9권4호
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• pp.607-616
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• 2005

7차 교육과정에서 추구하는 초등미술교육은 모든 학생이 화가가 되기를 바라는 것이 아니라 아름다움을 보고 느끼고 생활에 적용하여 보다 아름다운 생활을 가꾸어 갈 수 있는 심미적 인간을 기르고자 하는 것이다. 즉, 감상활동의 중요성이 나타나 있다고 할 수 있다. 그러나 교육현장 특히 학원가를 중심으로 감상영역 보다는 테크닉 위주의 학습이 행해지고 있는 것이 현실이며 도서 벽지의 학생들이 갤러리와 같은 물리적 공간에서 감상학습을 한다는 것은 더욱이 어렵고, 기존의 감상 자료들이 텍스트 기반으로 소수의 학생들만이 공유할 수 있다는 단점을 해결하고자 본 논문에서는 인간 감각 형태와 가장 비슷하다고 할 수 있는 웹 기반의 3차원적 학습 패턴을 기본으로 하는 갤러리 형태의 감상 학습 자료를 제공하는 시스템을 설계 및 구현하였다.

• 한국환경보건학회지
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• 제44권4호
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• pp.330-339
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• 2018

Objectives: The occurrence characteristics of BTEXS and phytoncides were investigated by type of urban forest. Methods: Four types of urban green space (Hongneung Forest, Mt. Chunjang, residential park, and traffic island) and Gwangneung Forest were selected. Monitoring of phytoncides and BTEXS was conducted considering the activity times of urban residents (five times per day) using a Tenax TA tube and suction pump in June 2017 (one day). Results: Phytoncide concentrations were ranked as Gwangneung Forest>Hongneung Forest>Mt. Cheonjang>traffic island>residential park. Relatively high concentrations of phytoncides were also identified in the urban forest. There was no significant difference between Gwangneung Forest and the urban forest. BTEXS concentrations were ranked as traffic island>residential park>Hongneung Forest>Gwangneung Forest>Mt. Cheonjang. Traffic island and residential park showed high levels of BTEXS depending on the inflow of vehicles. The difference in concentration by time was significant for the traffic island in particular. Pollutant levels in Hongneung Forest were as low as in Gwangneung Forest. Conclusion: The concentrations of phytoncides and BTEXS were different by types of urban green space, and the potential for health and hygiene of urban forests were able to be investigated. This study is expected to provide as basic data for the creation of urban forest spaces in the future.

• Tuberculosis and Respiratory Diseases
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• 제65권3호
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• pp.222-224
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• 2008

자발성 종격동기종은 기저질환이나 외상의 병력이 없이 발생할 수 있고 드물게는 운동중에 발생할 수 있다. 저자들은 23세 남자 환자에서 태권도중에 발생한 자발성 종격동기종 1예를 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다.

• 한국주거학회논문집
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• 제27권5호
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• pp.55-63
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• 2016

This study intended to establish a direction for the revitalization of youth culture centers by examining the current status of youth centers operated in Daejeon and how they have been used. Four youth centers in Daejeon were visited and a survey was conducted targeting 180 people using the centers. Frequency, Mean, and ${\chi}^2$ analysis were performed by using SPSS statistics package, and major research outcomes are as follows; There were 6 youth culture centers in Daejeon and showed a lower construction rate of 7.4% on the basis of 81 up, myun and dong. Most youth centers were small, around $300-500m^2$ in total floor area, and accommodated 100-200 people, and the space comprised multipurpose hall, cafeteria, open space, club space, multimedia space, information service room, and guide booth. There were no sports spaces among the target facilities. So, it has created the need for physical activity space to promote health & development. Most users visited centers with their friends and simply to use the facilities, and the satisfaction with the facilities was relatively high at 4.32. The role of the local community and financial support of the government is required to activate the youth culture. Also, for the role of youth culture center, it was suggested that the youth culture center should develop program which corresponds with the level of the youth and boast the interest of the youth.

• 한국콘텐츠학회논문지
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• 제16권1호
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• pp.274-284
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• 2016

본 연구는 테마형 박물관 중 하나인 춘천 애니메이션 박물관의 어린이 놀이공간(에어바운스)을 대상으로 실제 공간을 이용하는 어린이들의 놀이행태와 놀이환경을 분석하였다. 이를 위해 어린이들의 특성을 고려하여 사용자 조사법 중 사용자 관찰법과 사용자 행동 인터뷰 조사를 병행하였다. 사용자 관찰법을 통해 연구 대상지의 어린이 놀이행태를 분석한 결과, 신체 운동, 정서, 인지, 사회성 발달과 관련된 놀이행태가 모두 관찰되었으나, 매달리거나 역할놀이와 같은 일부 행동은 관찰되지 않았다. 사용자 관찰법과 인터뷰 조사 등을 종합하여 이용밀도(수용력) 제한, 연령별 공간구분, 동반자 대기공간 조성, 아동과 동반자간 친밀감형성을 위한 공간 조성, 안전요원의 배치 등의 다양한 계획적 함의들이 도출되었다. 이러한 연구결과는 추후 유사한 어린이 놀이공간의 계획 및 설계단계에서 유용한 가이드라인으로 활용될 수 있을 것이다.

• 한국생활과학회지
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• 제15권2호
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• pp.209-225
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• 2006

The purpose of this study is to research the actual condition of environment and management of outdoor play at child care centers in Seoul, and to present a planning guideline for outdoor play environment. For this purpose, data were collected by a structured questionnaire and subjects were 164 directors of child care centers located in Seoul. The contents of the questionnaire were composed of general facts about the respondent and facility, environmental condition, managerial condition, and director's understanding about outdoor play. The data were then analyzed using the frequency, percentage, mean and crosstab. The major results have shown the following: 1) Most child care centers in Seoul had some space for outdoor play. 62% of them used front yard and 11 % a rooftop. 2) The space usually included fixed play instruments such as slide and complex unit structures, sand play area, and open area. It also had many natural elements as shrubs and earth. 3) 78% of the centers had a schedule for outdoor play. The schedule operates flexibly according to each center's own day schedule. Generally, a time for outdoor play was 21 to 30 minutes. 4) The directors of child care centers thought highly of outdoor play for it contributes to the balanced development of children. They answered that equipments and spaces, program devices, and teacher's understanding are some of the important factors for active outdoor play. 5) Most of them wanted wood-working area (construction activity area), water play area, and cages.