• Quality Improvement in Health Care
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• v.30 no.1
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• pp.165-168
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• 2024

Quality improvement activities are especially important in middle to small-sized hospitals as well as in large hospitals. Hospital accreditation would play a crucial role in the re-establishment of the healthcare delivery system, which is now nearly collapsed in Korea. To achieve all these goals, it is also important to educate prospective medical personnel at college on the concepts of quality improvement and patient safety.

• Journal of Acupuncture Research
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• v.18 no.2
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• pp.175-185
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• 2001

Objectives : In order to study the effect of taping therapy on the activity of daily living of poststroke-hemiplegic patients, a clinical study was performed. Methods : Twenty patients with poststroke-hemiplegia were randomized into two groups. Ten patients treated with kinesio taping. The other ten patients didn't treat with kinesio taping. Tapes were applied to the Deltoid, Supraspinatus, Infraspinatus, Brachioradialis, Gluteus Maximus, Adductor muscles of the hip, Sartorius and Tibialis Anterior. The activity of daily living was measured with a modifted barthel index(MBI). The taping therapy was performed twice a week for 2 weeks. Results : In terms of improvement of activity of daily living, the smaple group showed statistically meningful increase after 2 times treatment compared with control group(p<0.05). In terms of self care score of MBI, the sample group showed statistically meningful increase after 1 time treatment with the control group(p<0.05). In terms of mobility score of MBI, the sample group showed statistically meningful increase after 3 times treatment with the control group(p<0.05). Conclusions : These results support that taping therapy is significantly effective in improvement of the activity of daily living of poststroke-hemiplegic patients.

• Korean Journal of Plant Resources
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• v.36 no.3
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• pp.198-206
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• 2023

The effectiveness of the extracts of Alnus japonica and Portulaca oleracea, which are effective in improving alcohol-induced liver damage, was confirmed using acute and chronic alcoholic liver injury animal models. In the acute alcoholic liver injury model, dieting Alnus japonica and Portulaca oleracea complex (ALPOC) at a dose of 50 mg/kg showed no significant change in liver or body weight, while measured plasma ALT activity to be deficient (28.12 U/ml) compared to the alcohol intake group (42.5 U/ml), and confirmed that restored it to an average level. It showed an improvement of 34.9% compared to the alcohol intake group. AST activity confirmed that it showed a very effective liver protection activity by showing a gain of 12.6%. The chronic alcoholic liver damage animal model demonstrated that ALT showed an improvement effect of 25%, and AST showed an effect similar to that of the positive control group, Hovenia extract. In addition, through H&E staining analysis, observed that the ALPOC improved the necrosis and bleeding of the liver. And the ALPOC group showed intense antioxidant activity of 127% or more compared to the alcohol intake group, and this was confirmed to have a very high activity, which is more than 20% higher than that of the hovenia fruit extract.

• The Microorganisms and Industry
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• v.19 no.2
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• pp.34-41
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• 1993

Industrial strain improvement is concerned with developing or modifying microorganisms used in production of commercially important fermentation products. The aim is to reduce the production cost by improving productivity of a strain and manipulating specific characteristics such as the ability to utilize cheaper raw materials or resist bacteriophages. The traditional empirical approach to strain improvement is mutation combined with selection and breeding techniques. It is still used by us to improve the productivity of organisms in amino acids, organic acids and enzymes production. The breeding of high L-lysine-producing strain Au112 is one of the outstanding examples of this approach. It is a homoserine auxotroph with AEC, TA double metabolic analogue resistant markers. The yield reaches 100 g/l. Besides, the citric acid-producing organism Aspergillus niger, Co827, its productivity reaches the advanced level in the world, is also the result of a series mutations especially with $^60Co{\gamma}$-radiation. The thermostable .alpha.-amylase producing strain A 4041 is the third example. By combining physical and chemical mutations, the strain A 4041 becomes an asporogenous, catabolite derepressed mutant with rifamycin resistant and methionine, arginine auxotroph markers. The .alpha.-amylase activity reaches 200 units/ml. The fourth successful example of mutation in strain improvement is the glucoamylase-producing strain Aspergillus niger SP56, its enzyme activity is 20,000 units/ml, 4 times of that of the parental strain UV-11. Recently, recombinant DNA approach provides a worthwhile alternative strategy to industrial strain improvement. This technique had been used by us to increase the thermostable .alpha.-amylase production and on some genetic researches.

• Journal of International Academy of Physical Therapy Research
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• v.9 no.4
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• pp.1636-1641
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• 2018

The purpose of this study was to investigate the relationship between the needs for environmental improvement and dementia patients' activity of daily living (ADL) and behavior and psychological symptoms of dementia (BPSD) in dementia patients living in urban type dementia care villages. The subjects of this study were 70 households with cognitive impairment and dementia among residents of dementia care village in Gunsan City. The survey was conducted with the permission of their family. Frequency analysis and descriptive statistical analysis were performed on the main variables to analyze the characteristics of the subjects. Bivariate correlation analysis was performed to verify the relationship between the two variables. According to the analysis results, the order of environment improvement was in the order of entrance (51.4%), toilet and stairs (48.6%), kitchen (11.4%), bedroom and laundry room (10.0%). In the relationship between the variables, The ADL was correlated with age (r=.315, p <.01), BPSD (r=.322, p<.01) and living environment inconvenience (r=.640, p<.01) while, living environment inconvenience correlated with environment improvement need (r=.669, p<.01). This study suggests that improvement of the residential environment of dwellers in dementia care villages, especially the stairway and entrance hall is necessary.

• International conference on construction engineering and project management
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• 2020.12a
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• pp.409-416
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• 2020

This paper proposes a study measuring productivity improvement by using a type of technology called "Machine Guidance" through work sampling in earthwork. Earthwork is the activity typically on the critical path, indicating that productivity for the activity is critical for managing schedule on time. Thanks to the development of sensing and information system technologies, productivity for earthwork has been improved. While there have been many studies investigating the application of a certain type of technology to earthwork, few studies have measured the productivity improvement and presented how the technology leads to productivity improvement. Based on the thorough literature review, it is hypothesized that Machine Guidance contributes to improving productivity of earthwork by reducing indirect workhours spent for information waiting and inspection. In addition to the literature review, this paper presents a research model to test the hypothesis by using the work sampling technique. By proving and quantifying the productivity improvement from the technology use, this study can help practitioners justify the investment for technology use, which will contribute to the deployment of technology and more effective execution of earthwork.

• Korean Journal of Pharmacognosy
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• v.38 no.4
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• pp.363-371
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• 2007

Schizandrae Fruits has been used as a traditional Oriental medicine for treatment of many stress-induced diseases. In the present study, we investigated inhibitory activity of enzymatic hydrolysate of Schizandrae fructus (SC-EX) in growth of tested intestinal microorganism and activity of bowel inflammation related enzyme. SC-EX was added to the proteose peptone-yeast extract-fildes (PYF) media to investigation the effect on the growth of type culture of intestinal microorganism. The growth of lactic acid bacteria such as Bifidobacterium species and Lactobacillus species was accelerated by more than 3% concentration of SC-EX. But, growth of harmfulness bacteria such as E.coli, Clostridium sp. Staphylococcus sp. Streptococcus sp. was inhibited by more than 3% concentration of SC-EX. Also, SC-EX was exhibited a concentration-dependent inhibitory activity of the bowel inflammation related enzymes. The SC-EX was showed 76% and 92% inhibitory activity of 5-lipoxygenase and cyclooygenase at 5% additional concentration respectively. Our results indicated that SC-EX may possess improvement effect on the intestinal flora and Anti-inflammatory effect on the bowel.

• Journal of Korean Academy of Nursing Administration
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• v.9 no.1
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• pp.5-18
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• 2003

Purpose : For improvement of nursing services in ambulatory unit, ambulatory nursing activity was identified and the required time by nursing activity was measured. Method : The data were collected from 4 tertiary hospitals and 2 secondary hospitals. The method of data collection was used the self-reporting method. The 123 nurse-work days and 137 nurse-aid-work days in 6 hospitals were analyzed. Results : As a result, 11 ambulatory nursing domains and 79 ambulatory nursing activities were confirmed. Above 50% of subjects performed the general outpatient affair domain. The percentage of total time spent in each domain were as follows : general outpatient affair domain, 58.3%, patient education ${\cdot}$ counseling domain, 10.8%, therapeutic care domain, 8.6% and so on. And the average hours were measured by activity and domain. Conclusion : For the improvement of ambulatory nursing care, the strategies that keep the legal standard of number of ambulatory nurse and exchange the nursing-aid for the nurse is needed. And it is also needed to standardize the ambulatory nursing services.

• Journal of Korean Society for Quality Management
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• v.45 no.3
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• pp.561-582
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• 2017

Purpose: The purpose of this study is to share the right conception of win-win partnership innovative activity. This study suggests the desirable methodology to Win-win Partnership. Also, through the in-depth analyzing of the existing problems, we intend to exclude such a formal and erroneous direction of the research. Methods: This study systematically analyzes the best cases of the win-win partnership focusing on the proceedings of the companies participating in the field of win-win Partnership at the national quality-circle contest. Results: This study reveals the underlying problems of win-win partnership innovative activity and draws the conclusion in the way of improvement about the win-win partnership innovative activity. This study also suggests the efficient method of the function and improvement of a system for activating win-win partnership innovative activity. Conclusion: Promoting the effective way of boosting win-win partnership innovative activity, we seek to improve the quality of the product among the companies, and let the a rising curve of the mutual growth continue among the companies by strengthening the competitiveness.

• Journal of Microbiology and Biotechnology
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• v.22 no.5
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• pp.607-613
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• 2012

Improvement of endoglucanase activity was accomplished by utilizing error-prone rolling circle amplification, supplemented with 1.7 mM $MnCl_2$. This procedure generated random mutations in the Bacillus amyloliquefaciens endoglucanase gene with a frequency of 10 mutations per kilobase. Six mutated endoglucanase genes, recovered from six colonies, possessed endoglucanase activity between 2.50- and 3.12-folds higher than wild type. We sequenced these mutants, and the different mutated sites of nucleotides were identified. The mutated endoglucanase sequences had five mutated amino acids: A15T, P24A, P26Q, G27A, and E289V. Among these five substitutions, E289V was determined to be responsible for the improved enzyme activity. This observation was confirmed with site-directed mutagenesis; the introduction of only one mutation (E289V) in the wild-type endoglucanase gene resulted in a 7.93-fold (5.55 U/mg protein) increase in its enzymatic activity compared with that (0.7 U/mg protein) of wild type.