• Title/Summary/Keyword: activity function

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The Effect of Sodium Orthovanadate on Renal Na-K-ATPase Activity and Renal Function in Rabbits (Vanadium이 신장 Na-K-ATPase에 미치는 영향)

  • Kim, I.S.;Lee, S.B.;Cho, K.C.
    • The Korean Journal of Pharmacology
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    • v.19 no.1
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    • pp.101-106
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    • 1983
  • Vanadium is widely distributed in animal tissues and it is supposed to be a regulator of Na-K-ATPase activity. The effect of sodium orthovanadate on Na-K-ATPase activity in rabbit kidney was measured in vitro and compared with that of ouabain. The influence of sodium orthovanadate on the renal function of rabbits was also investigated. 1) Na-K-ATPase activity was decreased by sodium orthovandate at the concentrations of $10^{-7},\;10^{-6},\;10^{-5}\;and\;10^{-4}\;M$ to 73.89, 36.49, 6.50 and 4.99% of the control activity respectively. 2) Na-K-ATPase activity was decreased by ouabain at the concentrations of $10^{-4},\;10^{-3}\;and\;10^{-2}\;M$ to 69.52, 22.84 and 3.88% of the control activity respectively. 3) Urine volume, urinary excretion of $Na^+,\;K^+\;and\;Cl^-$, clearances of inulin and p-amino-hoppuric acid were decreased until after 60 minutes following the administration of sodium orthovanadate 0.5 mg/kg intravenously $Na^+\;reasorption$ rate was not changed and mean arterial pressure was significantly elevated during 60 minutes after the administration of sodium orthovanadate.

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The Impact of Board Activity on The Audit Committee's Effectiveness Score: Empirical Evidence from Saudi Arabia

  • ALJAAIDI, Khaled Salmen;BAGAIS, Omer Ali;ADOW, Anass Hamad Elneel
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.1
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    • pp.179-185
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    • 2021
  • The aim of this study is to examine the impact of board of directors' activity on the audit committee's effectiveness score among manufactured listed companies on Saudi Stock Exchange (Tadawul) for the period 2015-2017. The final sample of this study consists of 195 firm-year observations that represent manufactured companies listed on Saudi Stock Exchange (Tadawul) for the years 2015-2017. The data of this study in terms of board of directors' meetings, audit committee size and meetings, firm leverage, firm performance, and firm age were hand-collected from the annual reports of the considered companies. The Pooled OLS regression's result indicate that audit committee's effectiveness score is influenced by the board of directors' activity. This result gives support to the agency theory prediction. This result is also consistent with the complementary function of corporate governance mechanisms in which board of directors' activity complements the function of audit committee's effectiveness score. The result of this study should be useful for manufacturing companies, Saudi Stock Exchange, auditors, and regulators which relates to the association between board of directors' activity and audit committee's effectiveness score. This study provides a new empirical evidence on the impact of board activity on the audit committee's effectiveness score in an interesting context which is Saudi Arabia.

The Effects of Table Tennis Program on Self Efficacy, Cardiopulmonary Function, Serum Lipids, Catalase Activity in the Physical Disabilities (탁구프로그램이 지체장애인의 자기효능감, 심폐기능, 혈청지질, Catalase 활성도에 미치는 영향)

  • Jeong, Yeong-Ju;Park, Jae-Gyeong;Yu, Gyeong-Won;Lee, Hee-Kyung;Kim, Mi-Ran;Kim, Kweon-Young
    • Journal of Korean Biological Nursing Science
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    • v.11 no.1
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    • pp.1-13
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    • 2009
  • Purpose: This study was conducted to evaluate the effects of table tennis program on self efficacy, cardiopulmonary function, serum lipids, catalase activity in the physical disabilities. Method: Physical disabilities were allocated to one of two groups: control group (n=7), experiment group (n=8). The experiment group took table tennis program four times a week for 12 weeks. Self efficacy was measured by questionnaire. Serum lipid profiles, catalase and cardiopulmonary function were checked after the exercise program and compared with pre-exercise data. Result: Self efficacy was significantly higher in the table tennis group. Maximum oxygen consumption and forced vital capacity were significantly increased and heart rate at rest was decreased in the table tennis group. Total cholesterol and triglyceride were decreased in the table tennis group. There was no significant change in catalase activity between two groups. Conclusion: These results indicate that table tennis program has positive effects on the health of the physical disabilities by improving the self efficacy and cardiopulmonary function and serum cholesterol profile.

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The Effect of Horticultural Therapy on Cognitive Function, Depression, Self-esteem and Activity Daily Living(ADL) in Dementia Care - A Systematic Review and Meta-Analysis - (치매환자의 인지기능, 우울, 자아존중감, 일상생활수행능력에 미치는 원예치유 효과 - 체계적 문헌고찰 및 메타분석 -)

  • Bae, Seung-Jong;Lee, Sun-Hee;Kim, Dae-Sik
    • Journal of Korean Society of Rural Planning
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    • v.27 no.4
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    • pp.97-107
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    • 2021
  • The purpose of this study is to systematically review and to objectively identify the effect size in order to understand the effects of horticultural therapy on cognitive function, depression, self-esteem, and activity daily living(ADL) of dementia patients. Related studies published in Korean and English were selected by searching domestic and foreign academic databases. The risk of bias assessment of individual studies was performed on the included 18 literatures. Horticultural therapy was found to be significantly effective in cognitive function(effect size=1.06), depression(effect size=0.64), self-esteem(effect size=0.99), and ADL(effect size=1.98) in dementia care. It is expected that related experimental studies will be repeatedly conducted to produce a more objective effect size calculation.

The Effect of Group Motor Activity Program on Motor Function and Self-efficacy of Children in the Community Children's Center (집단 운동 활동 프로그램이 지역아동센터 아동의 운동기능 및 자기효능감에 미치는 영향)

  • Kim, Hye Jin;Je, Young Hyeon;Seo, Jeong Min;Kim, Eun Young
    • The Journal of Korean Academy of Sensory Integration
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    • v.18 no.1
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    • pp.23-33
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    • 2020
  • Objective : The current study investigated the effectiveness of group motor activity programs on motor function and perceived self-efficacy of children in the community children's center. Methods : Nine children aged six to nine years participated in this study. We applied the group motor activity program for 7 sessions. Before and after the intervention, children's motor function and self-efficacy were assessed using the Bruininks-Oseretsky Test of Motor Proficiency, Second Edition, Short Form (BOT-2 SF) and the Perceived Efficacy and Goal Setting, Second Edition (PEGS-2), respectively. Results : The group motor activity program enhanced the motor function and self-efficacy of children. Conclusion : This study showed that the group motor activity program was effective for increasing the objective motor function and the subjective self-efficacy of children in the children's community centers. The result suggests that programs using activities in the community centers can facilitate children's self-development.

Resveratrol Extraction from Grape Fruit Stem and its Antioxidant Activity (포도 송이가지를 이용한 레스베라트롤의 추출 및 항산화 활성)

  • Cho, Cheol-Hee;Kim, So-Young;Yoo, Gui-Jae;Son, Min-Hee;Park, Keun-Hyoung;Lim, Byung-Lak;Kim, Dong-Chung;Chae, Hee-Jeong
    • Applied Biological Chemistry
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    • v.51 no.1
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    • pp.11-16
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    • 2008
  • The extraction conditions for resveratrol production from grape fruit stem, which is a by-product of grape processing, were optimized to develop high-functional grape-based products. Additionally, the bioefficacy of grape fruit stem extract (GFSE) as an antioxidant agent was evaluated. Resveratrol was extracted using various experimental conditions such as extractant type, extractant concentration, raw material-extractant ratio, extraction time and temperature, and the results were analyzed using a statistical program (SPSS). The resveratrol yield was the highest when 80% ethanol with a raw-material-extractant ratio of 1:10 (w/v) was used. In addition, the optimal temperature and time were selected as $60^{\circ}C$ and 90 min, respectively. When the antioxidant activity was analyzed and expressed as DPPH radical scavenging activity and SOD-like activity, the antioxidant activity of GFSE was higher than that of BHT, BHA and L-ascorbic acid. Finally, it was found that GFSE could be used as a raw material for the production of high antioxidant agents.

Relationships between Cognitive Function and Self Efficacy, Health Behavior of the Elderly Participation to Physical Activity (신체활동 참여 노인의 인지기능과 자기효능감, 건강행위와의 관계)

  • Park, Gyeong A;Oh, Myung Hwa
    • 재활복지
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    • v.20 no.1
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    • pp.189-210
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    • 2016
  • The purpose of this study was to investigate the relationships between cognitive function and self efficacy, health behavior of the elderly participation to physical activity. Data were collected from November 2015 to January 2016. The study subjects were 61, aged 65 years or older, to visit health town. The questionnaire was composed general characteristics and K-MoCA, self-efficacy scale, self-efficacy for exercise tools, Korea's elderly health behavior. The results of the study were as follows: As for cognitive function and exercise self-efficacy by general characteristics, there were differences in that regard according to gender, education, marital status, dependents form, duration of the program(p <.05), the general self-efficacy showed differences in gender, age, education, economic status, duration of the program(p <.05), and the health behavior showed differences in gender, education, marital status, dependents form, activity program, duration of the program(p <.05). There was a significant correlation between cognitive function and exercise self-efficacy, health behavior(p <.01). General self-efficacy was correlated with exercise self-efficacy, health behavior. And exercise self-efficacy was correlated with health behavior(p <.01). Exercise self-efficacy were the factor affecting the cognitive function(p <.01). Therefore, the activity program development for the practice and sustainable participation in physical activity in the elderly is believed to be made.

Effect of Mutations of Five Conserved Histidine Residues in the Catalytic Subunit of the cbb3 Cytochrome c Oxidase on its Function

  • Oh Jeong-Il
    • Journal of Microbiology
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    • v.44 no.3
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    • pp.284-292
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    • 2006
  • The cbb3 cytochrome c oxidase has the dual function as a terminal oxidase and oxygen sensor in the photosynthetic bacterium, Rhodobacter sphaeroides. The cbb3 oxidase forms a signal transduction pathway together with the PrrBA two-component system that controls photosynthesis gene expression in response to changes in oxygen tension in the environment. Under aerobic conditions the cbb3 oxidase generates an inhibitory signal, which shifts the equilibrium of PrrB kinase/phosphatase activities towards the phosphatase mode. Photosynthesis genes are thereby turned off under aerobic conditions. The catalytic subunit (CcoN) of the R. sphaeroides cbb3 oxidase contains five histidine residues (H2l4, B233, H303, H320, and H444) that are conserved in all CcoN subunits of the cbb3 oxidase, but not in the catalytic subunits of other members of copper-heme superfamily oxidases. H214A mutation of CcoN affected neither catalytic activity nor sensory (signaling) function of the cbb3 oxidase, whereas H320A mutation led to almost complete loss of both catalytic activity and sensory function of the cbb3 oxidase. H233V and H444A mutations brought about the partial loss of catalytic activity and sensory function of the cbb3 oxidase. Interestingly, the H303A mutant form of the cbb3 oxidase retains the catalytic function as a cytochrome c oxidase as compared to the wild-type oxidase, while it is defective in signaling function as an oxygen sensor. H303 appears to be implicated in either signal sensing or generation of the inhibitory signal to the PrrBA two-component system.

An investigation of factors influencing the participation of stroke survivors in social and leisure activities

  • Ahn, Si-Nae;Hwang, Sujin
    • Physical Therapy Rehabilitation Science
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    • v.7 no.2
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    • pp.67-71
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    • 2018
  • Objective: Participation restrictions are serious problems that stroke survivors experience while reintegrating into family, work, community, and social situations after participating in rehabilitation programs. The purpose of this study was to explore the factors affecting participation in activities of daily living (ADL), as well as social and leisure activities of individuals with hemiparetic stroke. Design: Cross-sectional study. Methods: The study involved 96 participants who were diagnosed with a first stroke 6 months before the study (58 men, 38 women; $60.3{\pm}14.3years$). The Berg Balance Scale, Modified Barthel Index, Manual Function test, and Activity Card Sort were used to assess static and dynamic balance function, upper limb function, level of independence, and their level of participation within the community. A regression analysis was used to identify the influence of factors affecting participation in ADL, social and recreational activities. Results: The Activity Card Sort scores were significantly affected by the Manual Function test and Modified Barthel Index scores (p<0.05). Participation in leisure activities was affected by the level of independence. Participation in social activities was affected by the balance function and level of independence of the participants. Conclusions: The results of this study have shown that participation restrictions are affected by upper limb function, balance function, and the level of independence in individuals with hemiparetic stroke.

Effects of Carthami Tinctorius on Rat Calvarial Cell Activity and MG63 Cell mRNA Synthesis (랫드의 두개골세포 활성 및 mRNA 발현에 미치는 홍화자의 영향)

  • Kim, Tae-Woong;Hwang, Gwi-Seo
    • Journal of Society of Preventive Korean Medicine
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    • v.11 no.1
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    • pp.9-21
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    • 2007
  • This study was performed to evaluate the effect of Carthami tinctorius(HH) on osteoblast function and gene expression. The osteoblasts separated from the rat calvariae were cultivated to evaluate the cell function, and MG-63 cell was also cultivated for the test of mRNA synthesis. In this experiments, cell proliferation of rat calvarial cells was increased by HH. PKC activity, intracellular free calcium level and collgen synthesis from calvarial cells were increased by HH, but not PKA activity. And the mRNA of $PLA_2$, COX-2, and $PGE_2$ synthase from MG-63 were decreased by HH, but the mRNA of prostacyclin synthase was increased. It is concluded that HH might increase the proliferation of calvarial cell resulted from augumentation of osteoblast activity and its mRNA synthesis.

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