• Title/Summary/Keyword: active principles

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Sedative activity and its active components of zizyphi fructus

  • Han, Byung-Hoon;Park, Myung-Hwan
    • Archives of Pharmacal Research
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    • v.10 no.4
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    • pp.208-211
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    • 1987
  • Sedative activity of Zizyphi fructus was evaluated by potentiation of hexobarbital-induced hypnosis test and its active principles have been characterized as nornuciferine and lysicamine. A new cyclopeptide alkaloid, daechucyclopeptide-1 was isolated together with zizyphusine.

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Shape and Compound Relationship in Ginseng Quality (인삼품질에 있어 체형과 화합물과의 관계)

  • Park Hoon;Lee Mee-Kyoung;Cho Byung Goo
    • Proceedings of the Ginseng society Conference
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    • 1988.08a
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    • pp.133-138
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    • 1988
  • The traditional concept of ginseng quality was investigated in relation to historical experiences. traditional quality measure and mordern analytical method. The traditional concept appears to be based on the original Korean thought of oneness in life and universe. The outside appearance such as shape and size in traditional quality measure includes the inside quality. Since certain shape and size define specific tissues. cells and biologically active substances in cells the traditional measure will he a map for analytical method to find active principles. Traditional method suggests that the balance among biologically active compounds seems to he more important than the large amount of one active compound and that the mode of active compounds in ginseng for the homeostasis of human body is the multicompound to multitarget system. Traditional method strongly suggests the importance of nitrogen compounds. especially soluble protein and heat stable protein for the balance of active principles since nitrogen compounds are more abundant in the central part (xylem-pith) that grows faster than the outer part (cortex-epidermis). The balance of physiologically active principles appeares to be meaningful in relation to the difference in traditional use of Panax species.

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Microbial Fuel Cells: Principles and Applications to Environmental Health (미생물 연료전지의 원리 및 환경보건 분야로의 응용)

  • Han, Sun-Kee
    • Journal of Environmental Health Sciences
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    • v.38 no.2
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    • pp.83-94
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    • 2012
  • The research on microbial fuel cells (MFCs) needs various knowledge of different fields such as electrochemistry, microbiology, environmental engineering, and material engineering. Although electrochemically active bacteria are very diverse, the performance of MFCs is affected primarily by the structure of the reactor system. Thus, the development in the system architecture is critical to lower internal resistance and increase power generation for commercialization. This paper summarizes the principles of MFCs and demonstrates the infinite potential of MFCs in various applications including wastewater treatment, biosensors, biohydrogen production, remote power sources, implantable medical devices, etc.

Search for Naturally Occurring Hypolipidemic Principles (천연에 존재하는 고지질혈증 개선 활성성분의 탐색)

  • 최재수;양한석
    • Journal of Life Science
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    • v.3 no.2
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    • pp.79-90
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    • 1993
  • The present paper reviews the active natural principles and crude extracts of plants which have been experimentally studied for hyploipidemic activity in the last decades. Phytoconstituents with known structures have been classified in appropriate chemical groups The data are reported on their pharmacological activity, mechanism of action and other properties. This review also describes the inducing method of experimental hypolipidemic animals appeared in the literature.

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Interface Design Principles for Digital Content (디지털 콘텐츠를 위한 인터페이스 설계 원칙)

  • Park, Sang-Jin
    • Proceedings of the Korea Contents Association Conference
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    • 2006.11a
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    • pp.860-864
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    • 2006
  • Various kinds of digital contents developers are recognizing the importance of interface design, but they have no integrated and arranged interface design principles, so are facing difficulties in applying them. About the interface of web-site which is one field of the digital contents, there came out necessary principles about the interface design to some extent by the active studying activities in and out of the country. However, the researchers are proposing various principles, so it is difficult to apply which design principle in what situation. To this, this study looks into the common design principles while comparing and analyzing the design principles of Donald A. Norman, Jakob Nielson, Jeff Johnson and Manna Sjoberg. Based on this, we suggest 10 interface design principles to improve the functionality and aesthetics of the digital contents.

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Characteristics of Boost Input Type Active Clamp Forward ZVS Converter (Boost 입력형 능동클램프 Forward ZVS Converter)

  • Oh Yong-Seung;Kim Hee-Jun
    • Proceedings of the KIPE Conference
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    • 2002.07a
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    • pp.386-389
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    • 2002
  • This paper proposes the boost input type active clamp forward ZVS(zero voltage switching) DC-DC converter which can provide high efficiency and improved EMI characteristics. Moreover, it has active clamp circuit for reducing the voltage stress and zero voltage switching technique for minimizing switching loss. The detailed operation principles and the simulation results are presented.

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Evidence-based herbal medicine in efficacy and safety assessments

  • Park, Jin-Han
    • Advances in Traditional Medicine
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    • v.8 no.2
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    • pp.103-110
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    • 2008
  • Herbal medicine is the use of medicinal plants for prevention and treatment of diseases: it ranges from traditional and popular medicines of every country to the use of standardized and tritated herbal extracts. Generally cultural rootedness enduring and widespread use in a traditional medical system may indicate safety, but also efficacy of treatments, especially in herbal medicine where tradition is almost completely based on remedies containing active principles at very low and ultra low concentrations or relying on magical-energetic principles. The efficacy and safety assessments of medicines, whether modern or herbal, invariably encounter challenges or problems during the course of pre-clinical and clinical research. Some of the challenges in evidence-based herbal medicinal research are unique, and the researcher must be cognizant of them in order to safeguard the quality of the data obtained. Key challenges are: the quality of raw materials; appropriateness of biological/pharmacological activity assessment methodology, and data interpretation; standardization methodology; pharmacokinetics and bioavailability of active constituents and metabolites; clinical dosage formulation/production; and clinical study designs and outcome measures.

Brassinosteroid-like Activity of Monoglyceride Analogues (Monoglyceride 관련물질의 Brassinosteroid-like 생물활성)

  • Park, Jong-Dae;Park, Keun-Hyung
    • Applied Biological Chemistry
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    • v.40 no.4
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    • pp.357-360
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    • 1997
  • The biological activity of monoglycerides, diglycerides, triglycerides and free fatty acids were investigated by the rice inclination test that is specific bioassay for brassinosteroids. The experimental results revealed that some diglycerides, triglycerides and free fatty acids as well as monoglycerides showed positive response. ${\alpha}-Monoolein$ and diolein as active principles showed higher activity than indole-3-acetic acid at the same concentration. From the results, it can be confirmed that the active principles are related to olein which especially have a high activity.

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Studies on the Active Principles of Wild Vegetables on Biotransformation of Drug (야생 식용식물의 약물대사 활성성분에 관한 연구)

  • Choi, Jae-Sue;Park, Si-Hyang;Kim, Il-Sung
    • Korean Journal of Pharmacognosy
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    • v.20 no.2
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    • pp.117-122
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    • 1989
  • The effect of wild vegetables such as Allium tuberosum, Allium monanthum, Sedum sarmentosum, Ixeris dentata and Capsella-bursa pastoris on hexobarbital induced hypnosis was tested in mice. Among them, the methanol extract of Allium tuberosum exhibited significant lengthening of the barbiturate hypnosis. When various fractions prepared from the methanol extract of the Allium tuberosum were administered, the chloroform, ethylacetate and butanol extracts caused a significant activity. Through systematic fractionation by $SiO_2$ column monitoring by bioassays, $1,2,3,4-tetrahydro-{\beta}-carboline$ 3-carboxylic acid from the butanol extract was isolated as one of the active principles of this plant.

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Anti-hyperlipidemic Effect of Phragmites communis and Its Active Principles (갈대의 고지혈증 개선효과와 그 활성성분)

  • 최재수;이지현;양한석
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.4
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    • pp.523-529
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    • 1995
  • Administration of an MeOH extract of Pharagmites communis on hyperlipidemic rats produced a significant decrease in blood triglyceride. The fatty acid mixtures, $\beta$ -sitosterol and its glucoside, p-coumaric acid, vanilic acid, ferulic acid, p-hydroxybenzaldehyde and sucrose were isolated. Sterol and p-coumaric acid were shown to be effective in reducing the elevated level of triglyceride. The wet weight and the level of triglyceride in epididymal adipose tissue increase following administration of the methanol extract in rats fed the purified diets at the 1% level for 4 weeks. This results suggest that the methanol extract may accelerate the accumulation of lipid in adipose tissue.

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