Studies on the Active Principles of Wild Vegetables on Biotransformation of Drug

야생 식용식물의 약물대사 활성성분에 관한 연구

  • Choi, Jae-Sue (Department of Nutrition and Food Science, National Fisheries University of Pusan) ;
  • Park, Si-Hyang (Department of Nutrition and Food Science, National Fisheries University of Pusan) ;
  • Kim, Il-Sung (Department of Nutrition and Food Science, National Fisheries University of Pusan)
  • 최재수 (부산수산대학 식품영양학과) ;
  • 박시향 (부산수산대학 식품영양학과) ;
  • 김일성 (부산수산대학 식품영양학과)
  • Published : 1989.06.30

Abstract

The effect of wild vegetables such as Allium tuberosum, Allium monanthum, Sedum sarmentosum, Ixeris dentata and Capsella-bursa pastoris on hexobarbital induced hypnosis was tested in mice. Among them, the methanol extract of Allium tuberosum exhibited significant lengthening of the barbiturate hypnosis. When various fractions prepared from the methanol extract of the Allium tuberosum were administered, the chloroform, ethylacetate and butanol extracts caused a significant activity. Through systematic fractionation by $SiO_2$ column monitoring by bioassays, $1,2,3,4-tetrahydro-{\beta}-carboline$ 3-carboxylic acid from the butanol extract was isolated as one of the active principles of this plant.

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