• 한국산업융합학회 논문집
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• 제7권3호
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• pp.299-303
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• 2004

A systematic investigation for the reactivity and solvent effect was studied on the reaction of optical resolving agents with the optically active assistant compounds. The reaction rate constants of the nucleophillic substitution reactions were determined by means of conductometric method The linear solvent energy relationship based on the solvent parameters and the thermodynamic parameters was discussed on the reactions of various physiological active compounds and optical resolving agents The reaction mechanism was discussed from the kinetic results compared with the optical purity.

• Tribology and Lubricants
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• 제15권3호
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• pp.272-277
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• 1999

The objective of this investigation is to examine the influence of the micro catheters, which mimic the intravascular micro active endoscopes, on local pressure changes and flow rate in an arterial branch model similar to the femoral artery of human. The effects of branch to main lumen flow rate ratios and the locations of a catheter tip were found to be significant on the local pressure changes. Relatively large pressure drops and an increase in shear stress due to the obstruction effects may induce an endothelial cell damage and a change in arterial wall permeability, which have been reported to be the primary cause of the initiation of the atherosclerosis and other major vascular diseases.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2003년도 봄 학술발표회 논문집
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• pp.403-410
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• 2003

A new semiactive control strategy for seismic response reduction using a neuro-controller and a magnetorheological (MR) fluid damper is proposed. The proposed control system adopts a clipped algorithm which induces the MR damper to generate approximately the desired force. The improved neuro - controller, which was developed by employing the training algorithm based on a cost function and the sensitivity evaluation algorithm replacing an emulator neural network, produces the desired active control force, and then by using the clipped algorithm the appropriate command voltage is selected in order to cause the MR damper to generate the desired control force. The simulation results show that the proposed semiactive neuro-control algorithm is quite effective to reduce seismic responses. In addition, the semi-active control system using MR fluid dampers has many attractive features, such as the bounded-input, bounded-output stability and small energy requirements. The results of this investigation, therefore, indicate that the proposed semi-active neuro-control strategy using MR fluid dampers could be effectively used for control of seismically excited structures.

• Journal of Pharmaceutical Investigation
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• 제40권4호
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• pp.201-212
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• 2010

Self-organized nanogels from polysaccharide derivatives offer a promising approach in treatment of cancer due to their flexibility in chemistry and their ability to improve the therapeutic index of a drug by modifying biodistribution by their preferential localization at target sites and lower distribution in normal healthy tissues. These properties have promoted studies of active cancer targeting by self-organized nanogels for even better accumulation in solid tumors. However although many researchers have reported their potential by using cell culture systems and small animal tumor models in cancer therapy, these nanogels need more decoration such as conjugation with targeting moiety and endowment of stimuli-sensitivity for precise targeting of the cancer site. In this review, we summarize the recent efforts in developing novel targeting approaches via active endocytosis and stimuli-sensitive systems responding to hyperthermic or acidic tumor pH conditions.

• 한국정밀공학회지
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• 제13권8호
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• pp.102-111
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• 1996

This paper presents a proof-of-concept investigation on an active tension control using an ER (electro-rheological) brake actuator. Firstly, an ERF (electro-rheological fluid) which has an inherent reversible feature from Newtonian fluid to Bingham fluid upon applying an electric field is composed, and its property is tested to obtain intrinsic parameters of the Bingham model. An appropriate size of the ER brake is manufactured on the basis of the Bingham model, and dynamic characteristics of the brake are experimentally identified. After formulating a governing equation of motion of the tension control system, a sliding mode controller is designed to achieve a certain desired level of tension. Both simulation and experimental works are undertaken in order to demonstrate the efficiency and feasibility of the proposed active tension control method.

• 한국소음진동공학회논문집
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• 제15권12호
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• pp.1408-1415
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• 2005

Active vibration control of smart hull structure using Macro Fiber Composite (MFC) actuator is performed. Finite element modeling is used to obtain governing equations of motion and boundary effects of end-capped smart hull structure. Equivalent interdigitated electrode model is developed to obtain piezoelectric couplings of MFC actuator. Modal analysis is conducted to investigate the dynamic characteristics of the hull structure, and compared to the results of experimental investigation. MFC actuators are attached where the maximum control performance can be obtained. Active controller based on Linear Quadratic Gaussian (LQG) theory is designed to suppress vibration of smart hull structure. It is observed that closed loop damping can be improved with suitable weighting factors in the developed LQG controller and structural vibration is controlled effectively.

• Smart Structures and Systems
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• 제15권3호
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• pp.863-879
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• 2015

This paper experimentally investigates the effectiveness and applicability of the time delay control (TDC) algorithm, which is simple and robust to unknown system dynamics and disturbance, for an active mass damper (AMD) system to mitigate the excessive vibration of a building structure. To this end, the theoretical background including the mathematical formulation of the control system is first described; and then, a thorough experimental study using a shaking table system with a small-scale three-story building structural model is conducted. In the experimental tests, the performance of the proposed control system is examined by comparing its structural responses with those of the uncontrolled system in the free vibration and forced vibration cases. It is clearly verified from the test results that the TDC algorithm embedded AMD system can effectively reduce the structural response of the building structure.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2005년도 추계학술대회논문집
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• pp.217-222
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• 2005

Active vibration control of smart hull structure using Macro Fiber Composite (MFC) actuator is performed. Finite element modeling is used to obtain governing equations of motion and boundary effects of end-capped smart hull structure. Equivalent interdigitated electrode model is developed to obtain piezoelectric couplings of MFC actuator. Modal analysis is conducted to investigate the dynamic characteristics of the hull structure, and compared to the results of experimental investigation. MFC actuators are attached where the maximum control performance can be obtained. Active controller based on Linear Quadratic Gaussian (LQG) theory is designed to suppress vibration of smart hull structure. It is observed that closed loop damping can be improved with suitable weighting factors in the developed LQG controller and structural vibration is controlled effectively.

• Journal of international Conference on Electrical Machines and Systems
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• 제1권2호
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• pp.30-37
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• 2012

This paper presents the performance investigation and design technology of a Line Start-up Permanent Magnet Synchronous Motor (LSPMSM) with super premium efficiency, including a design consideration and evaluation for motor start-up, key performance, and advanced finite element analysis FEA) for the design, improvement and verification, prototype build and test, design and test data comparison with a $Premium^{(R)}$ Efficient Induction Motor (PEIM). To assess the design technology, the LSPMSM prototype was built amended from a PEIM with the same frame, stator punching and rated output. Based on the prototype test, two novel design improvements and analyses have been done to eliminate noise and vibration. Additionally, the comparisons with the PEIM on the power factor, efficiency, frame size and active material consumption indicated that a significant performance improvement and active material cost reduction can be achieved by the LSPMSM.

• Parasites, Hosts and Diseases
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• 제58권5호
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• pp.559-564
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• 2020

A survey of rodents and chiggers associated with Orientia tsutsugamushi was conducted in a rural region of the Republic of Korea (Korea) between 2014 and 2018. Overall Apodemus agrarius 15.2% had the highest seropisitive for O. tsutsugamushi, followed by Myodes regulus 11.4%. Monthly risk factors using logistic regression analysis were not associated with O. tsutsugamushi infections in rodents. The overall prevalence rate of O. tsutsugamushi among chiggers was 0.3%. The chigger (Leptotrombidium scutellare) and monthly (October) risk factors were associated with O. tsutsugamushi human infections (P<0.05). Orientia tsutsugamushi infections are endemic in rodents in Korea and people, for example, soldiers who are active outdoors, must employ preventive measures, especially during October (P<0.05). When there are many reports of O. tsutsugamushi infections in Korea. The Boryong strain 85.7% (2/14) was the most common strain detected in chiggers, followed by the Shimokoshi 7.1% (1/14) and Karp 7.1% strains.