• Journal of Microbiology and Biotechnology
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• 제16권9호
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• pp.1434-1440
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• 2006

The stable anchorage of pyridoxal 5'-phosphate (PLP) in the active site of D-amino acid transaminase (D-AT) is crucial for the enzyme catalysis. The three-dimensional structure of D-AT revealed that Glu32 is one of the active site groups that may playa role in PLP binding. To prove the role of Glu32 in PLP stability, we firstly checked the rate of the potential rate-limiting step. The kinetic analysis showed that the rate of the ${\alpha}$-deprotonation step reduced to 26-folds in E32A mutant enzyme. Spectral analyses of the reaction of D-AT with D-serine revealed that the E32A mutant enzyme failed to stabilize the key enzyme-substrate intermediate, namely a quinonoid intermediate (E-Q). Finally, analysis of circular dichroism (CD) on the wild-type and E32A mutant enzymes showed that the optical activity of PLP in the enzyme active site was lost by the removal of the carboxylic group, proving that Glu32 is indeed involved in the cofactor anchorage. The results suggested that the electrostatic interaction network through the groups from PLP, Glu32, His47, and Arg50, which was observed from the three-dimensional structure of the enzyme, plays a crucial role in the stable anchorage of the cofactor to give necessary torsion to the plane of the cofactor-substrate complex.

• 한국환경보건학회지
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• 제22권3호
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• pp.98-102
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• 1996

This study investigated performance of the phenol degradation and reaction characteristics according to variation of phenol volumetric loading rates and dilution rates in suspension and PACT reactors using Pseudomonas sp. B3. 1. Removal efficiencies of the PAC unit indicated about 100 % with phenol volumetric loading rates from 0.4 phenol $kg/ma^3\cdot d$ to 1.2 phenol $kg/m^3\cdot d$, however, which of the suspension reactor showed about 100% with from 0.2 phenol $kg/m^3\cdot d$ to 0.75 phenol $kg/ma^3\cdot day$. 2. The cell density slightly was decreased from 298.2 mg/l to 272 mg/l, when dilution rate for suspension was reactor increased from 0.4 to 1.41 1/d, and also the cell density suddenly was decreased to 145.5 mg/l and was washed out at the dilution rate higher than 1.60 1/d. But the cell density for the PAC unit was linearly decreased with dilution rate of from 0.8 to 3.0 1/d, and showed 220.75 mg/l at maximum dilution rate. 3. The phenol utilization rate was increased from 0.008 to 0.031 phenol g/l$\cdot$h, when dilution rate for suspension reactor was increased from 0.4 to 1.5 1/d, however, the rate for the PAC unit was linearly increased from 0.017 to 0.061 phenol g/l$\cdot$h as variation changes from 0.017 to 0.061 phenol g/l$\cdot$h dilution rate.

• International Journal of Computer Science & Network Security
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• 제22권12호
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• pp.51-56
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• 2022

In space based constellation network, users are allowed to enter or leave the network arbitrarily. Hence, the number, identities and transmitted data of active users vary with time and have considerable impacts on the receiver's performance. The so-called problem of multiuser detection means identifying the identity of each active user and detecting the data transmitted by each active user. Traditional methods assume that the number of active users is equal to the maximum number of users that the network can hold. The model of traditional methods are simple and the performance are suboptimal. In this paper a Maximum A Posteriori Probability (MAP) based multiuser detection method is proposed. The proposed method models the activity state of users as Markov chain and transforms multiuser detection into searching optimal path in grid map with BCJR algorithm. Simulation results indicate that the proposed method obtains 2.6dB and 1dB E_b/N₀ gains respectively when activity detection error rate and symbol error rate reach 10^-3, comparing with reference methods.

• 한국재료학회지
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• 제31권12호
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• pp.710-718
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• 2021

Recently, due to high theoretical capacitance and excellent ion diffusion rate caused by the 2D layered crystal structure, transition metal hydroxides (TMHs) have generated considerable attention as active materials in supercapacitors (or electrochemical capacitors). However, TMHs should be designed using morphological or structural modification if they are to be used as active materials in supercapacitors, because they have insulation properties that induce low charge transfer rate. This study aims to modify the morphological structure for high cycling stability and fast charge storage kinetics of TMHs through the use of nickel cobalt hydroxide [NiCo(OH)₂] decorated on nickel foam. Among the samples used, needle-like NiCo(OH)₂ decorated on nickel foam offers a high specific capacitance (1110.9 F/g at current density of 0.5 A/g) with good rate capability (1110.9 - 746.7 F/g at current densities of 0.5 - 10.0 A/g). Moreover, at a high current density (10.0 A/g), a remarkable capacitance (713.8 F/g) and capacitance retention of 95.6% after 5000 cycles are noted. These results are attributed to high charge storage sites of needle-like NiCo(OH)₂ and uniformly grown NiCo(OH)₂ on nickel foam surface.

• 한국정보전자통신기술학회논문지
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• 제9권2호
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• pp.196-204
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• 2016

세계보건기구협회에의 통계에 따르면 심장 혈관 질환의 발병률이 가장 높은 것으로 알려져 있다. CTA영상을 사용하여 관상동맥 및 대동맥 질환을 치료 및 검사할 수 있다. 혈관을 3차원으로 복원하는 과정이 의사의 숙련도에 따라 결과가 상이하며 복원 시간이 길다는 단점이 있으며 이를 극복하고자 자동으로 정확한 혈관을 추출하는 연구들이 진행되어 왔다. 본 논문에서는 자동 및 반자동 분할 기법인 Region Competition, Geodesic Active Contour(GAC), Multi-atlas based segmentation, Active Shape Model(ASM) 알고리즘을 CTA영상에 적용하여 대동맥 기부를 추출하였으며 하우스도르프 거리, 볼륨, 영상처리속도, 사용자 관여 여부, 그리고 관상동맥 심문 검출률을 비교 및 분석하였다. 추출된 3차원 대동맥 모델 중 가장 높은 정확도를 나타낸 알고리즘은 GAC인 반면 사용자 관여가 가장 높았기 때문에 실제 시술에 적용하기 위해서는 자동 분할 알고리즘 개선이 필요하다

• 약학회지
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• 제29권6호
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• pp.357-361
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• 1985

Two glycosides, assumed to be one of the potential active principles, is isolate from the root bark of Acanthopanax koreanu Nakai, identified to be acanthoside D, $C_{34}H_{46}O_{18}$, mp $242^{\circ}C$, and syringo side, $C_{17}H_{24}O_{9}$ mp $192^{\circ}C$. Acanthoside D has been found to have s-GPT, s-GOT lowering effect, BSP-retention rate and survival rate in the toxic state through the bio-pharmacological experiments.

• 오토저널
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• 제5권1호
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• pp.32-44
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• 1983

In case of $K_{Imax}$ < $K_{Iscc}$, the corrosion fatigue of high strength steel in 0.1N $H_{2}$S $O_{4}$ solution and 3.5% salt water is as follows. 1. The fatigue life shortens in order of 3.5% salt water and 0.1N $H_{2}$S $o_{4}$ solution. 2. The fatigue crack growth rate in air is obtained as the following equation. (dc/dN)$_{atr}$=7.23*10$^{-6}$ (.DELTA. K)$^{2.23}$ 3. The corrosion fatigue crack growth rate in environment is divided into three regions, that is, First Region, Second Region and Third Region from the small cyclic stress intensity. 4. The formation rate of the active surface on metal is slower than the mechano-chemical reaction rate in First Region. The crack growth rate depends on time and the cyclic stress intensity and is expressed as the following equation. (dc/dN)$_{I}$=C(/DELTA. K)$^{\delta}$ 5. The formation rate of the active surface is faster than the mechano-chemical reaction rate in Second Region and the synergistic effect by stress and corrosion becomes slow. In case the fatigue load is large, we have the critical crack growth rate which is not related to the cyclic stress intensity. 6. The corrosion crack growth rate by the mechano-chemical reaction is the same in $H_{2}$S $O_{4}$ solution and salt water, so Hydrogen accelerates the crack growth. 7. The environment has no effect on the corrosion fatigue crack growth rate in Third Region. 8. In First Region and Second Region, dimple is observed on the fatigue fracture surface in 0.1N $H_{2}$S $O_{4}$ solution. 9. The striation is observed in any environment as in air in Third Region and its interval approximately coincide with the crack growth rate.ate.e.e.

• 소음진동
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• 제8권4호
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• pp.683-689
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• 1998

A control algorithm for multi-stage dampers is developed based on the mode skyhook control concept, and implemented on the full vehicle system environment. The test vehicle system is equipped with the real time controller, four-stage variable dampers and sensors. The real time controller is developed using a digital signal processor(DSP), digital I/O, A/D and D/A converters. The dampers are driven by the electromagnetic actuators of less than 20 msec response time. The sensors include accelerometers, relative displacement transducers, and steering wheel rate sensors, etc. Through a series of tests in laboratory and proving ground, the performance of the semi-active suspension system is evaluated and it is shown that the vehicle dynamic characteristics is improved with the developed damping system. Futhermore, the parameter tuning methods to enhance vehicle dynamic performance are propsoed.

• Corrosion Science and Technology
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• 제20권5호
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• pp.249-255
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• 2021

In this work, we proposed a facile method to fabricate the three-dimensional porous copper current collector (3D Cu CC) for a Si-dominant anode in a Li-ion battery (LiB). The 3D Cu CC was prepared by combining chemical etching and thermal reduction from a planar copper foil. It had a porous layer employing micro-sized Cu balls with a large surface area. In particular, it had strengthened attachment of Si-dominant active material on the CC compared to a planar 2D copper foil. Moreover, the increased contact area between a Si-dominant active material and the 3D Cu could minimize contact loss of active materials from a CC. As a result of a battery test, Si-dominant active materials on 3D Cu showed higher cyclic performance and rate-capability than those on a conventional planar copper foil. Specifically, the Si electrode employing 3D Cu exhibited an areal capacity of 0.9 mAh cm^-2 at the 300^th cycles (@ 1.0 mA cm^-2), which was 5.6 times higher than that on the 2D copper foil (0.16 mAh cm^-2).

• 한국광학회지
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• 제10권3호
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• pp.248-253
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• 1999

본 논문에서는 측면이 연마된 단일모드 광섬유와 폴리머 다중 평면도파로가 결합했을 때 발생하는 모드 결합현상을 이용한 능동형 광결합기를 연구하였다. 제안된 소자는 파장가변 광필터나 광변조기로 이용할 수 있을 뿐만 아니라, 광도파로 물질의 굴절률, 복굴절, 전기광학 계수, 열광학 계수 등을 측정하는 도구로 응용할 수 있다. BPM으로 최적화된 결합기를 설계하였고, 열광학 폴리머를 능동 평면 도파로층으로 이용하여 결합기를 제작하였다. 제작된 소자는 -0.5dB 이하 손실, 공진파장 -13dB 소멸비. 그리고 열광학 효과에 의해 -1.5nm/$^{\circ}C$ 정도의 파장 가변성을 보였다. 본 연구의 결과로 볼 때 열광학 능동형 광결합기는 광변조기, 파장가변 광필터, 광센서 등으로 이용될 가능성이 높다.