• 동의생리병리학회지
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• 제24권4호
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• pp.653-660
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• 2010

Pulsatillae Radix and Cicadidae Periostracum have long been used for treatment of injuries, inflammations or itchiness in Korea. This study was carried out to examine the acne-remedy effects of the mixture made with equal parts of Pulsatillae Radix extract and Cicadidae Periostracum extract (PRCP) compared with 2%-benzoyl peroxide (Standard) used commercially as anti-acne. The results showed the mixture (PRCP) was more effective than each crude drug extract. The 10%-PRCP showed significant antimicrobial activity against Propionibacterium acnes, the major cause of acne, and also showed significant inhibition from type 1 $5{\alpha}$-reductase ($5{\alpha}R$), another cause of acne, And the cream made with PRCP demonstrated anti-sebum and acne-improvement effects on examinee's facial skin.

• 한방안이비인후피부과학회지
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• 제16권2호
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• pp.177-188
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• 2003

Acne, which intrudes the pilosebaceous unit, is a chronic inflammatory disease. The symptom of comedones, papules, pustules, cysts, nodules and scar mainly raise on the face, upper back, shoulder and neck. The cause of acne is the secreting growth of sebum, abnormal follicular keratinization, the form of group of propionibacterium acnes, and the response of inflammation etc. But the original mechanism of the cytobiologic level is exactly not known yet. Chungsangbangpungtang is one of the most frequently used medical treatments for the acne. A study on 25 patients with acne who took Chungsangbangpungtang shows that the oral medication of Chungsangbangpungtang is the best efficient remedy for a person who has acne less than one year without nodules.

• 대한한방소아과학회지
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• 제21권1호
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• pp.27-40
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• 2007

Objectives : The purpose of this study is to make the oriental medical treatment useful, and to develop the ways of acne cure. Methods : Recent paper about Traditional Chinese medicine of acne was analyzed for this studying. Results : According to the latest researches of Acne treatment with Chinese medicine, oriental medical methods to chronic acne were effective. Conclusions : Oriental medical treatment can be classified into 3 parts; internal cure, external cure, and acupuncture therapy. All of these ways were efficacious to cure chronic Acne.

• 셀메드
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• 제10권2호
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• pp.15.1-15.9
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• 2020

Introduction: Buthūr Labaniyya (Acne vulgaris) is a multifactorial disorder of the pilosebaceous units characterized by non-inflammatory and inflammatory clinical lesions. Several Unani medications have been used for centuries to treat acne. Objectives: Evaluation of safety and efficacy of Tila-i Muhāsā in patients with acne vulgaris Materials and Methods: This clinical study was conducted in patients with acne vulgaris. Patients applied Tila-i Muhāsā or 5% Benzoyl Peroxide (BPO) once daily for 6 weeks. Assessment of efficacy was carried out by Global Acne Grading System (GAGS) and Patient Global Assessment (PGA) scores. In addition, overall severity of acne was evaluated on a 5-point Cook's acne grading scale using photographic standards. Assessment of safety was performed through adverse drug reactions, local dermal tolerability, vital signs, and routine laboratory investigations. Results: A total of 60 patients (30 in each group) completed 6 weeks of treatment. The mean percentage reduction in GAGS score at 6 weeks from baseline in Unani group (66.97%) and BPO group (59.09%) was statistically significant (P<0.0001). After 6 weeks of therapy, the mean percentage reduction in PGA score compared to baseline in Unani group (57.44%) and BPO group (50.23%) was statistically significant (P<0.0001). No serious adverse events were reported in both groups; however, mild adverse events occurred more frequently in BPO group (30%) compared to Unani group (10%). Conclusion: Tila-i Muhāsā was found to be effective and safe in the treatment of acne vulgaris. However, further clinical studies with larger sample size and longer duration of therapy need to be conducted.

• 대한한방부인과학회지
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• 제28권2호
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• pp.133-142
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• 2015

Objectives : Acne vulgaris is a common skin disorder prevalent among adolescence into adulthood, and its consequences can be detrimental especially for women. The purpose of this study was to investigate the effect of Yukul-tang Gamibang (YG) on female acne vulgaris. Methods : We treated 2 cases of female acne patients diagnosed as ‘Stagnation Pattern’ with herbal medication and external treatments. Herbal medication was orally administered 2 times a day and external treatments were applied once a week on average during the whole treatment period. Results : Photographs were taken at the start of each session, and the pictures of before and after the treatment period were compared. The severity of acne vulgaris was evaluated according to the Korean Acne Grading System (KAGS). We observed clinical improvement and decrease in KAGS grades after treatment. Conclusions : After taking YG, acne vulgaris was significantly improved in both patients. The results suggest that YG may be effective in treating acne vulgaris in female patients diagnosed as ‘Stagnation Pattern’.

• 대한본초학회지
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• 제34권3호
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• pp.37-44
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• 2019

Objectives : Acne is a common disease that affects more than 70% of adolescents. Acne patients have a poor quality of life compared to patients with other skin diseases. We tried to demonstrate the effectiveness of acne treatment using cleansing soap which is easily used in daily life. Methods : We selected 20 students with acne symptoms on their facial skin. We made herbal Cp (Cold process) soaps using Seosiokyongsan, Kyungohkgo, Hwangryunhaedoktang and Baeksoooh and distributed them to experiment participants. We let them wash their face in the morning and evening for 6 weeks using herbal Cp soap. Prior to the experiment, their skin condition was checked and assessed using A-ONE Smart One-Click Automatic Facial Diagnosis System three times at 3-week intervals. Acne status was classified into 6 stages according to KAGS and acne status was also measured 3 times in total. After the experiment, the changes of skin were analyzed through facial analysis test. Results : Based on the KAGS classification, the condition of acne has improved as a whole. The state of moisture was gradually increased and the state of skin oil was significantly decreased after 6 weeks of using soap compared to before using soap. Conclusions : Cp soaps made from four kinds of herbal medicine are believed to improve the condition of acne by increasing the moisture of the facial skin and decreasing the skin oil content.

• 사상체질의학회지
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• 제23권4호
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• pp.548-556
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• 2011

1. Objective To review the effectiveness affecting to acne patients by Yeoldahanso-tang(熱多寒少湯) and Hyangsayangyi-tang(香砂養胃湯) who were constitutionally typed as Taeeumin and Soeumin 2. Methods The patient's subjective and objective symptoms were observed. After treatment's we compared the photos before and after, and estimated by Korean Acne Grading System(KAGS-2) 3. Results After we treated two cases of acne patient with constitutional prescription, their symptoms and result of KAGS-2 improved 4. Conclusions This case study showed an effectiveness of using Sasang Constitutional prescription in Taeeumin and Soeumin to Acne.

• 한방안이비인후피부과학회지
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• 제19권3호통권31호
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• pp.215-223
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• 2006

Acne, which intrucdes the pilosebaceous unit, is a chronic inflammatory disease. The symptom of comedones, papules, pustules, cysts, nodules and scar mainly raises on the face, upper back, shoulder and neck. The cause of acne is the secreting growth of sebum, abnormal follicular keratiniziation, the form of group of propionibacterium acnes, and the respones of inflammation etc. But the original mechanism of the cytobiologic level is exactly not known yet. We treated three patients suffered from acne with acupuncture, venesection, Chungsangbangpung-tang, wet dressing with Gamihwangryunhaedok-tang. After treatments we observed the improvement. Based on this study, it is considered that acupuncture, venesection, Chungsangbangpung-tang wet drssing with Gamihwangryunhaedok-tang can be applied to the management of acne.

• 한방안이비인후피부과학회지
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• 제25권4호
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• pp.89-98
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• 2012

Objective : Photodynamic therapy (PDT) using topical aminolevulinic acid (ALA) has increasingly been used for the treatment of acne vulgaris and several studies have shown its clinical efficacy. However, ALA-PDT needs a relatively long incubation period and is frequently associated with adverse effects. Triptophan and Riboflavin has been introduced as a new photosensitizer for the treatment of acne recently. Method : 11 patients with acne vulgaris were received PDT with tryptophan and riboflavin four to six times over two to three months. The photos of each patient were taken before and after treatment. Result and conclusion : PDT with tryptophan and riboflavin may be an effective and safe treatment for the Acne vulgaris patients.

• Medical Lasers
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• 제10권4호
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• pp.242-245
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• 2021

Acne vulgaris is a common inflammatory skin disease of the pilose-baceous unit. It appears as lesions consisting of comedones, papules, pustules, and nodules of varying shapes and severity. In general, the first-line treatment for acne vulgaris includes topical and oral medication. Recently, various physical modalities have also been investigated. The use of laser therapy is steadily increasing because of its fewer side effects, short procedure time, and rapid results. In particular, laser therapy assisted with carbon suspension application is effective for acne vulgaris but may sometimes result in discomfort due to odor and dust formation during the procedure. Herein, we report that acne vulgaris and enlarged facial pores can be safely and effectively treated with laser therapy assisted with diamond particle suspension and gold microparticle application, which can address the discomfort caused by the carbon suspension application.