• 한국미생물·생명공학회지
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• 제1권2호
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• pp.105-113
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• 1973

1) 탄소원으로서 glucose medium에서 Brevibacterium flavum을 배양할때 Biotin 5${\gamma}$/1, Desthiobiotin 5${\gamma}$/1, 7.8-Diaminopelargonic acid 10${\gamma}$/l 에서 L-GA생성이 가장 양호하였다. 2) 탄소원으로서 glucose-acetate혼합배지를 4구분하여 사용한 결과 생육도, L-GA생성은glucose 2%-acetate 혼합배지가 가장 양호하였다. 3) 탄소원으로서 Methanol, Ethanol, Ethylacetate, Acetic acid (free acetate), Na-acetate :NH$_4$-acetate=2 : 1의 배지를 사용한 결과 Na-acetate : NH$_4$-acetate=2 : 1 > Acetic acid (free acetate) > Ethylacetate > Ethanol> Methanol 의 순으로 L-GA 생성이 나타났다. 4) 생장촉진제로 각종 Biotin vitamer를 첨가하고 탄소원으로 glucose 또는 Acetate 배지를 사용하였을때 요구되는 농도는 Biotin에 대하여 Desthiobiotin은 대략 동양, 7.8-Diaminopelargonic acid는 3~4배 였으며 Bisnorbiotin은 대체효과가 없었다.

• 한국의류산업학회지
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• 제7권1호
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• pp.85-90
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• 2005

The effect of sodium acetate to reduce the fiber damage and hardening of acetate fabrics during alkaline treatment is studied. The optimal condition is controlled concentration 2%, at $50^{\circ}C$ for 6 minutes and at $70^{\circ}C$ for 2 minutes through the result of weight loss, shrinkage and tensile strength. Alkaline treated acetate fabrics under optimal condition show softer than untreated acetate fabrics. Alkaline treatment with sodium acetate brings the reduction in hardening and shrinkage in internal fiber of acetate fabric. Also, alkaline treatment with sodium acetate improves the tensile strength of acetate fabrics compared with only alkaline treatment. The moisture regain of acetate fabrics is also improved by alkaline treatment under optimal condition.

• 한국미생물·생명공학회지
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• 제23권5호
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• pp.519-525
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• 1995

This study was carried out to enhance the production of sisomicin by Micromonospora inyoensis ATCC 276000. The effect of various sugars and organic acids as the supplements to a basal mineral medium was tested for the sisomicin production by fully grown mycelium. Among the substances tested, acetate and citrate greatly increased the production of sisomicin at the sixth day of culture. Especially, in the basal mineral medium containing 0.1M sodium acetate, sisomicin production was 6.7 times more than that in the same medium with glucose. When 0.1M sodium acetate was added in the fermentation medium initially, the cell growth was inhibited by sodium acetate, although specific productivity was higher than that in the same medium without sodium acetate. On the contrary, when sodium acetate was added to the culture after three days, the sisomicin production and specific productivity were 1.6 times higher than those in the same medium without sodium acetate. The results suggested that sodium acetate was a stimulating substance of sisomicin production by M. inyoensis.

• 한국응용곤충학회지
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• 제5_6권
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• pp.65-69
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• 1968

본 실험에 있어서는 phenylmercuric acetate에 못지 않은 살균력을 나타낸다고 보고된 phenylemercuric 8-oxyquinolinate를 phenylmercuric acetate 와 대비시켜 벼 고마엽고병균 에 대하여 먼저 균체의 건물량에 의한 균사발육 효과를 확인하고 포자 및 균사의 호흡 저해효과를 검토한 바 그 결과를 보고하는 바이다. (1) 균사발육 억제효과를 보면 phenylmercuric 8-oxyquinolinate는 phenylmercuric acetate보다 약간 떨어지나 현저한 차이는 없으며, 양자 모두 0.01ppm부터 1.0ppm까지의 사이에서 급격히 발육 억제효과가 증가한다. (2) 포자효흡 저해작용은 0.1ppm을 제외하고는 phenylmercuric acetate가 phenylmercuric 8-oxyquinolinate보다 약간 강하나 뚜렷한 차이는 인정할 수 없으며 0.01ppm에서는 거의 저해효과가 없는 듯하다. (3) 균사호흡 저해작용은 포자호흡과는 반대로 phenylmercuric 8-oxyquinolinate 가 phenylmercuric acctate 보다 강하며, 또한 그 차도 커서 약 $10\%$쯤 된다. (4) 이상의 결과로 미루어 보아 phenylmercuric 8-oxyquinolinate의 포자발아 억제효과는 phenylmercuric acetate와 동정도이거나 약간 높으며, 균사발육 억제효과는 phenylmercuric acetate보다 낮음이 명백하다.

• Journal of Pharmaceutical Investigation
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• 제35권3호
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• pp.173-177
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• 2005

Addition of 30% propylene glycol was required to maintain sink condition in the evaluation of percutaneous absorption of estradiol and norethindrone acetate. The permeability of estradiol was higher in silicone and SIS adhesives. However, estradiol was crystallized in silicone, SIS, and SBS adhesive matrix. The permeability ratio of estradiol or norethindrone acetate from acrylic pressure sensitive adhesives varied widely depending on the functional group of the acrylic adhesives. PEO grafting to acrylic adhesive seemed to change physicochemical property of acrylic adhesive and increased the permeability of estradiol and norethindrone acetate significantly. On the contrary, highly cross-linked enhancer compatible acrylic adhesive decreased the permeability of both estradiol and norethindrone acetate. $Span^{\circledR}$ 20 provided the highest enhancing effect on the permeability of both estradiol and norethindrone acetate followed by oleic acid and $Crovol^{\circledR}$ EP40. The permeability of the drugs from the developed system was comparable to that from commercial $Combitran^{\circledR}$, although significantly lower amount of estradiol and norethindrone acetate were loaded in the developed system.

• 한국연초학회지
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• 제22권2호
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• pp.157-163
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• 2000

Filter hardness is important to filter and cigarette manufactures because it is directly related to the ability of a plugmaker during making filter and to the acceptability of the filter by the consumer. In general, glycerol triacetate(Triacetin, TA) is the currently used common plasticizer in making filters from cellulose acetate tow and the effect of triacetin on hardness of filter which is made of mono cellulose acetate tow was well known. But unfortunately, the effect of triacetin on the hardness of cellulose acetate filter containing ativated carbon(carbon filter) was not reported so far. In this study, we manufactured filters with various carbon content at different triacetin concentrations and then analyzed the filter hardness and pressure drop. Filter hardness was directly increased with triacetin concentration but pressure drop was not affected and the effect of carbon content on filter hardness was smaller than that of triacetin concentration. However, pressure drop was directly increased with carbon content.

• 생약학회지
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• 제44권4호
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• pp.379-383
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• 2013

Portulaca oleracea L. is known to have many biological benefits such as anti-oxidant, anti-inflammatory, anti-allergic and anti-tumor. The objective of this study is to explore the neuroprotective effect of P. oleracea L. against glutamate-induced oxidative stress in mouse hippocampal HT22 cells. P. oleracea L. 70% ethanol extract and solvent fractions have the potent neroprotective effects on glutamate-induced nerotoxicity by induced the expression of heme oxygenase (HO)-1 in HT22 cells. Especially, ethyl acetate fraction showed higher protective effect. In HT22 cell, P. oleracea L. treatment with ERK inhibitor (PD98059) and c-JUN N-terminal kinase (JNK) inhibitor (SP600125) reduced P. oleracea L. ethyl acetate fraction induced HO-1 expression and P. oleracea L. ethyl acetate fraction also increased ERK and JNK phosphorylation. Furthermore, we found that treatment of P. oleracea L. caused the nuclear accumulation of Nrf2. In conclusion, the ethyl acetate fraction of 70% ethanol extract of P. oleracea L. significantly protect glutamate-induced oxidative damage by induction of HO-1 via Nrf2, ERK and JNK pathway in mouse hippocampal HT22. Taken together these finding suggest that P. oleracea L. ethyl acetate fraction is good source for taking active compounds and may be a potential therapeutic agent for brain disorder that induced by oxidative stress and neuronal damage.

• 한국응용과학기술학회지
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• 제35권4호
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• pp.1269-1275
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• 2018

Raphiolepis indica (R. indica) is one of evergreen shrubs belonging to the Rosaceae and is grown wildly in Jeju. This study was performed to evaluate the hepatoprotective effect of different fractions (n-hexane, dichloromethane, ethyl acetate, butanol, water) from R. indica. Anti-oxidative effects were determined using 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging activity and total phenol contents. Hepatoprotective effect was identified by 3-[4, 5-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide (MTT) assay in Huh7 cells. Among various fractions, ethyl acetate and butanol fractions showed the lowest DPPH remained rate reaching approximately 78.7 and 65.5% at $400{\mu}g/mL$. Ethyl acetate and butanol fractions showed the total phenolic content at 164.5 and 137.3 mg GAE/g extract. The ethyl acetate and butanol fractions were resistant against oxidative stress in MTT assay and showed higher hepatoprotective effect than other fractions. Therefore, these results suggest that the ethyl acetate and butanol fractions of R. indica might have therapeutic value in liver damage.

• Environmental Analysis Health and Toxicology
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• 제1권1호
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• pp.37-46
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• 1986

Experiments were performed to investigate the effect of Panax ginseng petroleum ether fraction on delayed type hypersensitivity, rosette formation, phagocytic activity and histophathological influence in lead acetate treated mice. Lead acetate was administered in the drinking water and ginseng pet. ether fraction was injected i.p.. Mice were sensitized and challenged with sheep red blood cells. Erythrocyte(I) rosette formation and DTH reaction were significantly depressed in lead acetate treated mice, and those were restored administration of ginseng fraction. Ginseng pet. ether fraction administration did not have any effect on decreased phagocytic activity. Follicular and parafollicular areal destruction of spleen, and destruction of thymus were finded in lead acetate exposed-mice. Small dose of ginseng pet. ether fraction (5 mg/kg, 10 mg/kg), administraction inhibited those histopathological changes, but large dose (20 mg/kg) didn't.

• 한국재료학회지
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• 제28권4호
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• pp.227-234
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• 2018

We investigate the effect of the modification of cellulose acetate propionate as an organic vehicle for silver paste on solar cell efficiency. For the modification of cellulose acetate propionate, poly(ethylene glycol) is introduced to the hydroxyl groups of a cellulose acetate propionate backbone via esterification reaction. The chemical structure and composition of poly(ethylene glycol) functionalized cellulose acetate propionate is characterized by Attenuated total reflectance Fourier transform infrared, $^1H$ nuclear magnetic resonance, differential scanning calorimetry and thermogravimetric analysis. Due to the effect of structural change for poly(ethylene glycol) functionalized cellulose acetate propionate on the viscosity of silver paste, the solar cell efficiency increases from 18.524 % to 18.652 %. In addition, when ethylene carbonate, which has a structure similar to poly(ethylene glycol), is introduced to cellulose acetate propionate via ring opening polymerization, we find that the efficiency of the solar cell increases from 18.524 % to 18.622 %.