• Advances in Computational Design
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• v.7 no.1
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• pp.69-79
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• 2022

In this research, the aeroelastic instability of a tail section manufactured from aluminum isotropic material with different shell thickness investigated. For this purpose, the two degrees of freedom flutter analytical approach are used, which is accompanied with simulation by finite element analysis. Using finite element analysis, the geometry parameters such as the center of mass, the aerodynamic center and the shear center are determined. Also, by simulation of finite element method, the bending and torsional stiffnesses for various thickness of the airfoil section are determined. Furthermore, using Lagrange's methods the equations of motion are derived and modal frequency and critical torsional/bending modes are discussed. The results show that with increasing the thickness of the isotropic airfoil section, the flutter and divergence speeds increased. Compared of the obtained results with other research, indicates a good agreement and reliability of this method.

• Structural Engineering and Mechanics
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• v.85 no.1
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• pp.81-88
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• 2023

This paper begins by analyzing cable vibrations due to external excitations and their effects on the overall dynamic behavior of cable-stayed bridges. It is concluded that if the natural frequency of a cable approaches any natural frequency of the bridge, the cable loses its rigidity and functionality. The results of this analysis explain the phenomenon that occurred on the Dubrovnik Bridge in Croatia during a storm and measures for its retrofit. A field test was conducted before the bridge was opened to traffic. It was concluded: "The Bridge excited unpleasant transverse superstructure vibration with the frequency of approximately 0.470 Hz. Hence, it seems possible that a pair of stays vibrating in phase may excite deck vibrations". Soon after this Bridge opened, a storm dumped heavy damp snow in the area, causing the six longest cable stay pairs of the main span to undergo large-amplitude vibrations, and the superstructure underwent considerable displacements in combined torsion-sway and bending modes. This necessitated rehabilitation measures for the Bridge including devices to suppress the large-amplitude vibrations of cables. The rehabilitation and monitoring of the Bridge are also presented here.

• Advances in Computational Design
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• v.8 no.1
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• pp.37-59
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• 2023

Squat reinforced concrete (SRC) shear walls are a critical part of the structure for both office/residential buildings and nuclear structures due to their significant role in withstanding seismic loads. Despite this, empirical formulae in current design standards and published studies demonstrate a considerable disparity in predicting SRC wall shear strength. The goal of this research is to develop and evaluate hybrid and ensemble artificial neural network (ANN) models. State-of-the-art population-based algorithms are used in this research for hybrid intelligence algorithms. Six models are developed, including Honey Badger Algorithm (HBA) with ANN (HBA-ANN), Hunger Games Search with ANN (HGS-ANN), fitness-distance balance coyote optimization algorithm (FDB-COA) with ANN (FDB-COA-ANN), Averaging Ensemble (AE) neural network, Snapshot Ensemble (SE) neural network, and Stacked Generalization (SG) ensemble neural network. A total of 434 test results of SRC walls is utilized to train and assess the models. The results reveal that the SG model not only minimizes prediction variance but also produces predictions (with R²= 0.99) that are superior to other models.

• Advances in Computational Design
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• v.8 no.1
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• pp.61-76
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• 2023

Fiber reinforced polymer (FRP) columns are increasingly being used in various engineering fields due to its high strength to weight ratio and corrosion resistance. Being a thin-walled structure, their designs are often governed by buckling.Buckling strength depends on state of stress of elements which is greatly influence by stacking sequence and various inaccuracies such as geometric imperfections and imperfections due to eccentricity of compressive load and non-uniform boundary conditions. In the present work, influence of load eccentricity on buckling strength of FRP column has been investigated by conducting parametric study. Numerical analyses were carried out by using finite element software ABAQUS. The finite element (FE) model was validated using experimental results from the literature, which demonstrated good agreement in terms of failure loads and deformed shapes.The influence of load eccentricity on buckling behavior is discussed with the help of developed graphs.

• Advances in Computational Design
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• v.8 no.1
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• pp.77-96
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• 2023

Calculating size-dependent mechanical properties of the nano-scale materials usually involves cumbersome numerical and theoretical works. In this paper, we aim to present a closed-form relation to calculate the length-dependent Young's modulus of carbon nanotubes (CNTs) based on nonlocal elasticity theory. In this regard, a single wall carbon nanotube (SWCNT) is considered as a rod structure and the governing nonlocal equations are developed under uniaxial tensile load. The equations are solved using analytical methods and strain distribution, total displacement and the size-dependent equivalent Young's modulus are obtained. Further, the results are compared with the molecular dynamics results from the literature. The outcome indicates that the calculated relations are coincident with the molecular dynamics results.

• Advances in Computational Design
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• v.8 no.3
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• pp.191-217
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• 2023

The objective of this study was to evaluate the foundation structure of a 3.6-MW wind turbine generator (WTG) installed offshore in Western Korea. The ultimate limit state (ULS) and fatigue limit state (FLS) of the multi-pile steel foundation (MSF) installed at the Saemangeum offshore wind farm were structurally investigated using the finite element (FE) software, ANSYS Workbench 19.0. According to the ULS analysis, no plastic deformation was found in any of the components constituting the substructure. At the same time, the maximal stress value reached the calculation limit of 335 MPa. According to the FLS results, the stress concentration factor (SCF) ranged from 1.00 to 1.88 in all components. The results of this study can be applied to determine the optimal design for MSFs.

• Advances in Computational Design
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• v.8 no.3
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• pp.255-271
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• 2023

The gear drive of a combat aircraft engine is responsible for power transmission to the different accessories necessary for the engine's operation. Incorrect power transmission can occur due to the presence of failure modes in the gears like bending fatigue, pitting, adhesive wear, scuffing, abrasive wear and polished wear etc. Fault diagnosis of the gear drive is necessary to get an early indication of failure of the gears. The present research is to develop an algorithm using different vibration signal processing techniques on industrial vibration acquisition systems to establish gear fault diagnosis architecture. The signal processing techniques have been used to extract various feature vectors in the development of the fault diagnosis architecture. An open-source dataset of other gear fault conditions is used to validate the developed architecture. The results is a basis for development of artificial intelligence based expert systems for gear fault diagnosis of a combat aircraft engine.

• Advances in Computational Design
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• v.8 no.2
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• pp.179-190
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• 2023

In this paper, building information modelling (BIM) associated to the principle of significant items emerged at quantities and costs in the optimization of productivity related to the rehabilitation of the building where proposed and discussed. A quantitative and qualitative study related to the field of application based on some parameters such as pathology diagnosis, projects documents and bills of quantities were used for model development at the preliminary stage of this work. The study identified 14 quantities significant items specified to cost value based on the use of the 80/20 Pareto rule, through the integration of building information modelling (BIM) in the optimisation of labour productivity for rehabilitation of buildings. The results of this study reveal the reliability and the improvement of labour productivity using building information modelling process integrating quantities and cost significant items.

• Biomolecules & Therapeutics
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• v.31 no.4
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• pp.388-394
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• 2023

Nitric oxide (NO) is a signaling molecule that plays a crucial role in numerous cellular physiological processes. In the skin, NO is produced by keratinocytes, fibroblasts, endothelial cells, and immune cells and is involved in skin functions such as vasodilation, pigmentation, hair growth, wound healing, and immune responses. NO modulates both innate and adaptive immune responses. As a signaling molecule and cytotoxic effector, NO influences the function of immune cells and production of cytokines. NO is a key mediator that protects against or contributes to skin inflammation. Moreover, NO has been implicated in skin sensitization, a process underlying contact dermatitis. It modulates the function of dendritic cells and T cells, thereby affecting the immune response to allergens. NO also plays a role in contact dermatitis by inducing inflammation and tissue damage. NO-related chemicals, such as nitrofatty acids and nitric oxide synthase (NOS) inhibitors, have potential therapeutic applications in skin conditions, including allergic contact dermatitis (ACD) and irritant contact dermatitis (ICD). Further research is required to fully elucidate the therapeutic potential of NO-related chemicals and develop personalized treatment strategies for skin conditions.

• Advances in Computational Design
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• v.7 no.4
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• pp.371-393
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• 2022

This paper presents a three-dimensional flexible pavement simulated in ANSYS subjected to moving vehicular load on the surface of the pavement typical for the road section in Nepal. The adopted finite element (FE) model of pavement is validated with the classical theoretical formulations for half-space pavement. The validated model is further utilized to understand the damping and dynamic response of the pavement. Transient analysis of the developed FE model is done to understand the time varying response of the pavement under a moving vehicle. The material properties of pavement considered in the analysis is taken from typical road section used in Nepal. The response quantities of pavement with nonlinear viscoelastic asphalt layer are found significantly higher compared to the elastic pavement counterpart. The structural responses of the pavement decrease with increase in the vehicle speed due to less contact time between the tires of the vehicle and the road pavement.