• Title/Summary/Keyword: access probe

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Backbone assignment of HMGB1 A-box and molecular interaction with Hoxc9DBD studied by paramagnetic probe

  • Choi, Ji Woong;Park, Sung Jean
    • Journal of the Korean Magnetic Resonance Society
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    • v.25 no.2
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    • pp.17-23
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    • 2021
  • High mobility group protein B1 (HMGB1) is a highly conserved, non-histone, chromatin associated nuclear protein encoded by HMGB1 gene. HMGB1 proteins may be general co-factors in Hox-mediated transcriptional activation that facilitate the access of Hox proteins to specific DNA targets. It is unclear that the exact binding interface of Hoxc9DBD and HMGB1. To identify the interface and binding affinity of Hoxc9DBD and HMGB1 A-box, the paramagnetic probe, MTSL was used in NMR titration experiment. It is attached to the N-terminal end of HMGB1 A-box by reaction with thiol groups. The backbone assignment of HMGB1 A-box was achieved with 3D NMR techinques. The 15N-labeled HMGB1 A-box was titrated with MTSL-labeled Hoxc9DBD respectively. Based on the chemical shift changes we can identify the interacting residues and further map out the binding sites on the protein structure. The NMR titration result showed that the binding interface of HMGB1 A-box is around loop-1 between helix-1 and helix-2. In addition, the additional contacts were found in N- and C-terminus. The N-terminal arm region of Hoxc9DBD is the major binding region and the loop between helix1 and helix2 is the minor binding region.

Performance of an Efficient Association Control Scheme for Public Wireless LAN Systems (고속 공중 무선랜 시스템을 위한 효율적인 연결 요청 제어방법의 성능분석)

  • Lee Hyun woo;Kim Se han;Ryu Won;Yoon Chong ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.3A
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    • pp.209-216
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    • 2005
  • This paper generally relates to the field of wireless local area networks(WLANs), and more particularly, to AP selection and association methods for the performance of a station. In these days, IEEE 802.11 Wireless LAN network is widely deployed and used as an emerging service to connect high-speed Internet in the public wireless environment. But, if there are many users in hot spot area, they suffer a severe decrease of performance. Thus it needs an association and access control mechanism especially when it is used in the public environment. In this paper, we suggest a selection and association method using Beacon or Probe Response frames based IEEE 802.11. Station selects AP using the information of the capacity area in a Beacon or a Probe Response frame. According to the present paper, an association method for a public WLAN service, which includes a WLAN user terminal and an AP for relaying WLAN communications to and from the user terminal, includes the steps of the user terminal asking the AP's states for access to a radio channel; and the station selects and associates with the AP According to the above-described selection in a high speed wireless Internet service based on public WLAN technologies that are currently in operations. Further, it is possible to improve the efficiency of network management.

A Study of an Association Admission Method for Public Wireless LAN Systems (고속 공중 무선랜 시스템을 위한 효율적인 연결 수락 제어방법의 연구)

  • Lee, Hyun-Woo;Yoon, Hong;Yoon, Chong-Ho
    • Journal of Advanced Navigation Technology
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    • v.7 no.2
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    • pp.149-155
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    • 2003
  • This paper generally relates to the field of wireless local area networks(WLANs), and more particularly, to AP selection and association methods for the performance of a station. In these days, IEEE 802.11 Wireless LAN network is widely deployed and used as an emerging service to connect high-speed Internet in the public wireless environment. But, if there are many users in hot spot area, they suffer a severe decrease of performance. Thus it needs an association and access control mechanism especially when it is used in the public environment. In this paper, we suggest a selection and association method using Beacon or Probe Response frames based IEEE 802.11. Station selects AP using the information of the capacity area in a Beacon or a Probe Response frame. According to the present paper, an association method for a public WLAN service, which includes a WLAN user terminal and an AP for relaying WLAN communications to and from the user terminal, includes the steps of the user terminal asking the AP's states for access to a radio channel; and the station selects and associates with the AP. According to the above-described selection in a high speed wireless Internet service based on public WLAN technologies that are currently in operations. Further, it is possible to improve the efficiency of network management.

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Percutaneous Discectomy of Herniated Intervertebral Disc with a Dekompressor(R) (요추 추간판 탈출증에서 Dekompressor(R)를 이용한 경피적 수핵 감압술)

  • Cho, OiGyeong;Kim, Chan;Han, Kyung Ream;Lee, Hyun Ho;Cho, Hye Won
    • The Korean Journal of Pain
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    • v.18 no.2
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    • pp.192-197
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    • 2005
  • Background: Radicular pain, associated with herniated intervertebral disc, has been treated with either conservative treatments or a traditional surgical discectomy. Several modalities for minimally invasive percutaneous procedures have been developed as alternatives to a surgical discectomy. Percutaneous decompression using a $Dekompressor^{(R)}$ probe has been recently introduced. Herein, we report the outcome of percutaneous decompression with a $Dekompressor^{(R)}$ for the treatment of a herniated intervertebral disc. Methods: Between August 2004 and April 2005, percutaneous decompression was performed using a $Dekompressor^{(R)}$, 1.5-mm percutaneous lumbar discectomy probe in 17 patients with a herniated lumbar intervertebral disc resistant to conservative treatments, with the results reviewed retrospectively. The procedure was performed under fluoroscopic guidance after local anesthesia. Disc access was gained with a posterolateral approach on the symptomatic side and intradiscal placement of the discectomy probe in the herniated disc confirmed from the anteroposterior and lateral views on the fluoroscopy. Results: We obtained satisfactory clinical results in 14 patients with a decrease in the initial Visual analogue scale (VAS) of more than 55% and the elimination or reduction of analgesic medication, with a follow-up of 3 to 11 months. Conclusion: We concluded that a percutaneous discectomy with a $Dekompressor^{(R)}$ probe might be an effective alternative for the treatments of painful disc herniations resistant to conservative managements when performed under proper selection criteria.

Development of SD-OCT for Imaging the in vivo Human Tympanic Membrane

  • Cho, Nam-Hyun;Jung, Un-Sang;Kwon, Hyeong-Il;Jeong, Hyo-Sang;Kim, Jee-Hyun
    • Journal of the Optical Society of Korea
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    • v.15 no.1
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    • pp.74-77
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    • 2011
  • We report a novel extension of 840 nm wavelength- based spectral domain optical tomography to in vivo/real-time human middle ear diagnosis. The system was designed to access the middle ear region with a specifically dedicated handheld probe. The real-time displaying feature was mandatory for in vivo imaging human subject with the handheld probe, and the system could provide about 20 frames per second for 2048 pixels by 1000 A-scans without using any graphics process units under the Labview platform. The inner ear structure of a healthy male volunteer was imaged with the developed system with the axial and lateral resolutions of $15\;{\mu}m$ and $30\;{\mu}m$, respectively. The application of the OCT technology to early diagnose otitis media(OM) is very promising and could be another extensive branch in the OCT field because it provides the depth resolved image including tympanic membrane (TM) and structures below TM whereas the conventional otoscope technique only gives asurface image of the TM.

Design and Fabrication of Wideband Antenna Using E-shaped Stacked Patches for IMT-Advanced AccessPoint. (E형 적층패치를 이용한 4세대 이동통신 AccessPoint용 광대역 안테나의 설계 및 제작)

  • Yoon, Hyun-Soo;Choi, Byoung-Ha
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2007.10a
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    • pp.223-228
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    • 2007
  • In this paper, Wideband antenna using E-shaped stacked patches has been designed and fabricated for 4th generation mobile communication(IMT-Advanced) AccessPoint application. E-shaped patch was miniature and brodband by made the movement route of current long. And inductive of coaxial probe compensates capacitive by slot. Therefore we fabricated to improve the bandwidth of proposed antenna. The E-shaped single patch antenna has an impedance bandwidth of about 13%(510[MHz]), By adding a second patch at the top of the first patch a bandwidth of 56%(2060[MHz]). The final fabricated antenna could have a good return loss(Return loss ${\leq}-10dB$) and a high gain(over 9.6dBi) at the range of 3.23 ${\sim}$ 5.29 [GHz].

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A Study on Flow Velocity Distribution at Inlet and Exit of Diesel Particulate Filter with L-Shape Inlet Connector Using Automatic Measurement (측정자동화에 의한 입구연결부 형상이 L-형인 디젤매연필터 입.출구에서의 유속 분포에 관한 연구)

  • Lee, Choong-Hoon;Bae, Sang-Hong;Choi, Ung;Lee, Su-Ryong
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.16 no.4
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    • pp.93-100
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    • 2007
  • The flow velocity distribution at inlet and exit of Diesel Particulate Filter(DPF) by fabricating L-shape connector with the DPF was measured using a Pitot-tube and 2-D transverse machine. An adaptor designed for making the Pitot tube probe access to the inlet and exit of the DPF was connected with the inlet and exit flange of the DPF, respectively. The Pitot tube which was mounted in the 2-D positioning machine could access to the inlet and exit of the DPF through the rectangular window of the adaptor. The L-shape connector in the DPF inlet has a flow guide which is a perforated steel pipe. The flow velocity distribution at the inlet of the DPF showed a chaotic velocity distribution which is different from that with a diffuser type connector. The velocity distribution at the exit of the DPF showed a crown shape which is similar to that of the diffuser type connector. The velocity distribution at the exit of DPF showed different patterns according to the air flow rate.

Asymmetric Signal Scanning Scheme to Detect Invasive Attacks (침투 공격 검출을 위한 비대칭 신호 스캐닝 기법)

  • Da Bin Yang;Ga Young Lee;Young-woo Lee
    • Smart Media Journal
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    • v.12 no.1
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    • pp.17-23
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    • 2023
  • Design-For-Security (DFS) methodology is to protect integrated circuits from physical attacks, and that can be implemented by adding a security circuit to detect abnormal external access. Among the abnormal accesses called invasive attack, microprobing and FIB circuit editing are classified as the most powerful methods because they have direct access. Microprobing deliberately inject defects into the wire of circuit through probes, or reads and changes data. FIB circuit editing is methods of reconnecting or destroying circuits to neutralize security circuits or to access data. Previous DFS methodology have responded to the attacks by detecting arrival time asymmetry between the two signals or by comparing input/output data based on encrypted communication. This study conducted to reduce hardware overhead, and the proposed circuit detects the reflected signal asymmetry generated through probe or FIB circuit editing and detects the attacks through comparison. Since the proposed security circuit reduces the size and test cycle of the circuit compared to previous studies, the cost used for security can be reduced.

Tool-path Generation for a Robotic Skull Drilling System (로봇을 이용한 두개골 천공 시스템의 공구 경로 생성)

  • Chung, YunChan
    • Korean Journal of Computational Design and Engineering
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    • v.18 no.4
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    • pp.243-249
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    • 2013
  • This paper presents a tool-path generation methods for an automated robotic system for skull drilling, which is performed to access to some neurosurgical interventions. The path controls of the robotic system are classified as move, probe, cut, and poke motions. The four motions are the basic motion elements of the tool-paths to make a hole on a skull. Probing, rough cutting and fine cutting paths are generated for skull drilling. For the rough cutting path circular paths are projected on the offset surfaces of the outer top and the inner bottom surfaces of the skull. The projected paths become the paths on the top and bottom layers of the rough cutting paths. The two projected paths are blended for the paths on the other layers. Syntax of the motion commands for a file format is also suggested for the tool-paths. Implementation and simulation results show that the possibility of the proposed methods.

Development of Integrated Product Information Model Using STEP (STEP 을 이용한 통합제품정보모델(IPIM) 개발)

  • Suh, Hyo-Won;Yoo, Sang-Bong
    • Journal of Korean Institute of Industrial Engineers
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    • v.21 no.3
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    • pp.441-461
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    • 1995
  • This research proposes an Integrated Product Information Model (IPIM) using STEP (Standard for the Exchange of product model data) for Computer Integrated Manufacturing (CIM) of Concurrent Engineering (CE). IPIM is based on Geometry and Topology (STEP Part 42), Form Feature (STEP Part 48), and Tolerance (STEP Part 48) for representing the integrated information of mechanical parts. For the IPIM, 1) new entities are developed for integration of existing entities, and 2) the existing entities are restructured and modified for a special application protocol. In CIM or CE, the advantages of using IPIM having integrated form of geometry, feature and tolerance are 1) integration of product design, process design and manufacturing sequentially or concurrently. 2) keep the product data consistency, modified by different domain, and 3) automatic data exchange between different application software and different hardware. The prototype system is composed of CAD, Data Probe, DBMS and SDAI (Standard Data Access Interface), and the generated STEP data is stored in a step file of DBMS for other applications.

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