• Parasites, Hosts and Diseases
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• 제38권3호
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• pp.119-138
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• 2000

Korean vivax malaria had been prevalent for longtime throughout the country with low endemicity. As a result of the Korean war (1950-1953), malaria became epidemic. In 1959-1969 when the National Malaria Eradication Service (NMES) was implemented, malaria rates declined, with low endemicity in the south-west and south plain areas and high endemic foci in north Kyongsangbuk-do (province) and north and east Kyonggi-do. NMES activities greatly contributed in accelerating the control and later eradication of malaria. The Republic of Korea (South Korea) was designated malaria free in 1979. However, malaria re-emerged in 1993 and an outbreak occurred in north Kyonggi-do and north-west Kangwon-do (in and/or near the Demilitarized Zone, DMZ) , bordering North Korea. It has been postulated that most of the malaria cases resulted from bites of sporozoite-infected females of An. sinensis dispersed from North Korea across the DMZ. Judging from epidemiological and socio-ecological factors, vivax malaria would not be possible to be endemic in South Korea. Historical data show that vivax malaria in Korea is a typical unstable malaria. Epidemics may occur when environmental, socio-economical, and/or political factors change in favor to malaria transmission, and when such factors change to normal conditions malaria rates become low and may disappear. Passive case detection is a most feasible and recommendable control measure against the unstable vivax malaria in Korea in cost-effect point of view.

• 한국지형학회지
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• 제26권3호
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• pp.1-17
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• 2019

Naeseongcheon is Korea's representative sand stream, and it is one of the regions where the dynamic changes of various river topography developed in the sand bed can be observed. Most of drainage area near of the river channel are formed with Daebo granite, and the granite weathering zone is developed at the surface of hill. Due to the massive input of sediment flux, braided channel reaches are found some of the area. However, the results of the study shows that the alluvial layer is very thin in some reaches. In addition, bedrock or weathered materials, including the Tors are exposed at the channel beds. On the other hand, during the flood, a considerable amount of sediment was introduced, causing the massive sediment to be close to 1m thick. In addition, despite the short distance, large changes in the particle size and sorting of the sediment were observed. Vegetation, on the other hand, has been shown to have a significant effect on the development of the overall channel bed topography, as reported in previous studies. In small floods or low water levels, vegetation's protection role of the surface is predominates, but in large flood conditions, herbaceous loss at the surface of the point bars, accelerating the erosion of surface.

• 한국레이저가공학회지
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• 제10권4호
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• pp.13-17
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• 2007

Electron beam weldability was investigated for 1mm thick cold rolled sheets of commercially pure grade titanium and Ti-6Al-4V alloy. Accelerating voltage of 40kV, beam current of 6mA, and weld speed of 0.8m/min was used and focal position of focused electron beam was just on the surface of workpiece. Microstructure of weld metal, the heat affected zone and base metal was observed using optical microscope. Vickers hardness was measured across the welds and the transverse tensile test was carried out. Hydroformability test was also carried out for the butt welded coupons of commercially pure grade titanium. For the electron beam welded C P Ti, the average grain size was equiaxed $\alpha(15{\sim}25{\mu}m)$ for base metal, coarse equiaxed $\alpha(80{\sim}200{\mu}m)$ for weld metal and annealed and enlarged grain($40{\sim}120{\mu}m$) for the HAZ. The vickers hardness of C P Ti was $180{\sim}200Hv$ for base metal, and $160{\sim}180Hv$ for the weld metal and the HAZ. For the electron beam welded Ti-6Al-4V alloy, the vickers hardness was 360Hv for the base metal, abd $400{\sim}425Hv$ for the weld metal and the HAZ. All the failure occurred at the base metal, when the transverse weld tensile test was carried out for both electron beam welded C P Ti and Ti-6Al-4V alloy. The formability of electron beam welded C P Ti was decreased compared with that of C P Ti base alloy.

• Molecules and Cells
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• 제41권5호
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• pp.465-475
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• 2018

The advent of massively parallel sequencing, also called next-generation sequencing (NGS), has dramatically influenced cancer genomics by accelerating the identification of novel molecular alterations. Using a whole genome sequencing (WGS) approach, we identified somatic coding and noncoding variants that may contribute to leukemogenesis in 11 adult Korean acute myeloid leukemia (AML) patients, with serial tumor samples (primary and relapse) available for 5 of them; somatic variants were identified in 187 AML-related genes, including both novel (SIN3A, C10orf53, PTPRR, and RERGL) and well-known (NPM1, RUNX1, and CEPBA) AML-related genes. Notably, SIN3A expression shows prognostic value in AML. A newly designed method, referred to as "hot-zone" analysis, detected two putative functional noncoding variants that can alter transcription factor binding affinity near PPP1R10 and SRSF1. Moreover, the functional importance of the SRSF1 noncoding variant was further investigated by luciferase assays, which showed that the variant is critical for the regulation of gene expression leading to leukemogenesis. We expect that further functional investigation of these coding and noncoding variants will contribute to a more in-depth understanding of the underlying molecular mechanisms of AML and the development of targeted anti-cancer drugs.

• 사물인터넷융복합논문지
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• 제8권3호
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• pp.63-68
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• 2022

코로나19로 인하여 기존의 제조 시설에 많은 패러다임의 변화와 비대면 서비스의 확대가 전 세계적으로 가속화되고 있다. 대표적인 기술이 디지털 트윈기술이다. 이러한 디지털 트윈기술은 과거에 개념적으로만 존재하던 것이 최근 5G 기반의 네트워크가 구성되며 실현 가능해졌다. 이에 본 논문은 이러한 패러다임의 변화에 맞추어 USB 공정 일부를 실제 사물 객체와 가상현실 기반의 USB 공정과정을 표준 연동구조인 OPC UA 통신을 기반으로 디지털 트윈이 가능하도록 설계하고 구현하였으며, 이때, 가상세계에 실제 사물의 물리적 특성을 같이 반영하여 이를 실제 사물과 실시간으로 동기화한 시뮬레이션이 가능하도록 하였다. 향후 이는 다양한 산업 분야에 적용 가능하며, 의사결정을 위한 비용 절감 및 위험한 사고로부터 예방이 가능할 것으로 기대한다.

• Steel and Composite Structures
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• 제48권1호
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• pp.59-71
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• 2023

Corrosion of the headed studs shear connectors is an important factor in the reduction of the durability and mechanical properties of the steel-concrete composite structure. In order to study the effect of stud corrosion on the mechanical properties in the negative moment region of steel-concrete composite beams, the corrosion of stud was carried out by accelerating corrosion method with constant current. Static monotonic loading was adopted to evaluate the cracking load, interface slip, mid-span deflection, and ultimate bearing capacity of four composite beams with varying corrosion rates of headed studs. The effect of stud corrosion on the stiffness of the composite beam's hogging moment zone during normal service stage was thoroughly examined. The results indicate that the cracking load decreased by 50% as the corrosion rate of headed studs increase to 10%. Meanwhile, due to the increase of interface slip and mid-span deflection, the bending stiffness dropped significantly with the same load. In comparison to uncorroded specimens, the secant stiffness of specimens with 0.5 times ultimate load was reduced by 25.9%. However, corrosion of shear studs had no obvious effect on ultimate bending capacity. Based on the experimental results and the theory of steel-concrete interface slip, a method was developed to calculate the bending stiffness in the negative bending moment region of composite beams during normal service stage while taking corrosion of headed studs into account. The validity of the calculation method was demonstrated by data analysis.

• 보존과학회지
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• 제32권3호
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• pp.353-364
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• 2016

구리 현릉의 능상석조물은 주로 자철석계열의 흑운모화강암으로 구성되었으며 풍화도가 높다. 손상 특성으로는 미생물 및 토사 유입과 흑색오염물의 발생률이 높게 나타났다. 봉분 부재에 대한 손상도 평가 결과, 토사(50.5%)와 지의류(47.6%)의 피도가 주요 요인으로 나타났으며 북면에서 지의류 외의 생물생육(8.6%)이 두드러진다. 표면오염물은 광물산화와 부재간 이음부에서 석고가 생성되었고 주요 변색양상인 흑색은 유기물에 의한 것으로 해석되었다. 각 단위 부재별 초음파 측정 결과, 평균 2,195 m/s의 속도로 심한풍화(HW)가 진행된 상태이며 대부분 부재에서 4~5등급에 도시되었다. 따라서 현릉의 능상석물에 대한 보존처리가 필요한 상태로 판단된다. 훼손을 촉진하는 토사 및 높은 점유율을 보이는 지의류 등 생물오염 세척과 상당한 풍화가 진행된 부재에 대한 강화 및 접합 충전이 요구된다. 또한 Ca를 주성분으로 하는 보수물질과 백화에 대한 제거 및 재처리 여부에 대한 논의가 필요하다 .

• 한국조경학회지
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• 제43권6호
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• pp.109-126
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• 2015

본 연구는 백사실계곡 생태 경관보전지역의 생물다양성 확보와 건강한 생태계 유지에 필요한 정밀 자료를 구축하고, 보전지역 특성에 맞는 생태적 관리계획을 제시하고자 하였다. 연구기간은 2010년 4월부터 2013년 5월까지이다. 백사실계곡은 최근 시민들의 이용 증가와 외래식물 식재 및 확산이 되고 있어 생태계 교란이 가속화 되고 있다. 주요 연구내용은 보호지역 관리시스템 고찰, 유역권 차원의 생태적 관리 필요성 고찰, 관리계획 수립 체계 설정, 사례 대상지 현황조사 및 분석, 위협요인 도출, SWOT 분석을 통한 목표 설정, 관리 전략, 관리계획 수립이었다. 현황조사 항목은 자연기반 환경, 동 식물 현황, 이용 환경으로 구분하여 파악하였다. 백사실계곡 생태 경관보전지역의 생태적 관리계획의 목표는 양서류의 안정적인 산란 및 서식을 위한 유역권 관리, 까막딱다구리의 영구적 서식 유도를 위한 산림 식생 보전 및 복원, 대경목 느티나무 군락 경관 보전을 위한 기반 환경 관리, 보호생물의 안정적 서식을 위한 이용자 관리로 설정하였다. 세부 관리계획 내용으로 보전 계획은 상류부 점 비점오염원 관리, 자생식물 생육환경 확보, 안전한 양서류 서식처 확보, 주요 야생조류 서식지 확보를 제시하였고, 복원 계획은 인공림의 자연림 복원, 자생초본 및 외래초본 관리, 훼손된 숲길 복원을 제시하였다.

• 대한토목학회논문집
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• 제28권6C호
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• pp.339-347
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• 2008

현장 관입 실험은 프로브 관입에 따라 주변 지반을 의도적으로 파괴시켜 지반특성을 파악할 수 있다. 본 논문의 목적은 현장 점토지반에 서로 다른 크기의 프로브 관입으로 인한 간극 수압 소산 특성을 이용하여 파괴에 따른 교란 효과를 분석하는 것이다. 현장 실험을 수행하기 위해 콘관입 시험(CPT), 딜라토미터 시험(DMT) 그리고 현장 속도 프로브 장비(FVP: Field Velocity Probe)가 사용되었다. 샌드 매트(sand mat), PBD 그리고 사석을 이용한 지반 개량 중인 부산 북컨테이너 현장에서 실험이 진행 되었으며, 샌드 매트(sand mat)공법 이후 실내 실험을 수행하기 위해 시료가 채취 되었다. 실내에서는 물성치 실험 및 압밀 실험을 수행하여 지반 특성과 수평압밀계수 값을 도출하였다. 현장 실험은 지반 개량 후 압밀도 90% 시점에서 사석 제거 후 케이싱을 통해 CPT, DMT 그리고 FVP 순서대로 실험이 수행 되었다. 관입에 따른 영향 범위를 최소화 시키기 위해 각각의 실험은 3m 간격을 유지 하였으며, 매 심도 24m에서 관입을 멈추고 시간에 따른 간극 수압 변화 양상을 측정하였다. 실내 압밀 실험을 통해 수평 압밀 계수$(C_h)$를 산정하였으며, 현장 실험을 통해 각 프로브에 따른 $t_{50}$ 값을 계산 하였다. $t_{50}$값을 이용하여 산정된 등가 유효 반경은 FVP가 가장 작게 그리고 DMT가 가장 크게 산정되었다.

• 한국환경복원기술학회지
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• 제9권2호
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• pp.59-71
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• 2006

Due to the rapid process of industrialization the cities of Korea confront changes of climate, destructions of the habitate and decrease of the green. Recently Seoul and other local governments have implemented policies and projects to improve the environmental surroundings. In reality, however, those policies and projects face difficulties in the course of implementation. The fact that there are no concrete regulations and specific legal procedures turns out to be one of the main difficulties. The aim of this study is to present specific plans and methods of wall-planting and to provide basic guidelines for the future direction of wall-planting and offer ideas of facilitating wall-planting. This study is based on questionnaires from specialists of landscape architecture through individual interviews and/or e-mails. The questionnaire is consisted of following 4 sections. 1. Show the experts current regulations and/or legal procedures and ask them improvements and suggestions. 2. Ask them choose matters of the highest priority by using Ricardo's diagram method. 3. Ask them to make a graded list in terms of the location and method of wall-planting. 4. Study the maketability of the wall-planting products currently in circulation. The city of Seoul and the Ministry of Environment recommend that trellis and/or planting inducement structures be installed on the building wall by regulation. The specialists responded to the questionnaire advocate that green wall without trellis should be allowed as green zone. Therefore regulations concerning the wall-planting should be determined specifically according to the characteristics of individual plants and walls. It has been urged that legal aid and social support must be reinforced to establish rules dealing with wall-planting. The respondents also point out that significant cutting down of the tax is far more effective in accelerating the wall-green instead of administrative support. The highest priority in terms of planting has been given to sound-proof wall, retaining wall and building wall. Concerning the maketability of the wall-planting products, panel products are recommended for early-planting and building planting. It has been suggested that the research and study of new materials and species be done in advance.