• 제목/요약/키워드: abnormal development

검색결과 1,209건 처리시간 0.027초

MRI Findings to Predict Neurodevelopmental Outcomes in Preterm Infants Near Term-Equivalent Age

  • Hong, Hyun Sook;Kim, Sung Shin;Park, Ga Young
    • Investigative Magnetic Resonance Imaging
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    • 제24권1호
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    • pp.30-37
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    • 2020
  • Purpose: Preterm infants are at high risk for adverse neurodevelopmental outcomes. Magnetic resonance imaging (MRI) has been proposed as a means of predicting neurodevelopmental outcomes in this population. It is controversial whether diffuse excessive high signal intensity (DEHSI) represents damage to the white matter or delayed myelination in preterm infants. This study investigated MRI findings for predicting the severity of neurodevelopmental outcomes and assessing whether preterm infants with DEHSI near term-equivalent age have abnormal neurodevelopmental outcomes. Materials and Methods: Preterm infants (n = 64, gestational age at birth < 35 weeks) undergoing brain MRI near term-equivalent age and subsequent neurodevelopmental outcomes were evaluated between 18 and 24 months of age. The associations of MRI findings and the risk of severe cognitive delay, severe psychomotor delay, cerebral palsy (CP), and neurosensory impairment were analyzed. The associations of DEHSI with risks of severe cognitive delay, severe psychomotor delay, CP, and neurosensory impairment (hearing or visual impairment) were analyzed. Outcome data were evaluated by logistic regression and the Fisher's exact test. Results: There were significant associations between abnormal white matter findings and delayed mental development, delayed psychomotor development, neurosensory impairment, and presence of CP. The presence of DEHSI was not correlated with delayed neurodevelopmental outcomes or presence of CP. In multivariate logistic regression analyses, cystic encephalomalacia, punctate lesion, loss of white matter volume and ventricular dilation were significantly associated with CP. Conclusion: Abnormal MRI findings near term-equivalent age in preterm infants predict adverse neurodevelopmental outcomes. No significant association between DEHSI and adverse neurodevelopmental outcomes was demonstrated.

기술·사회적 특성을 고려한 워터프론트 도시의 리질리언트 공간계획 (A Planning Direction of Resilient Waterfront City considering Technological and Social Meaning)

  • 이금진;최진희
    • 한국재난정보학회 논문집
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    • 제14권3호
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    • pp.352-359
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    • 2018
  • 연구목적: 본 연구는 급속히 진행되는 온난화로 인해 발생되는 예측 불가한 기상이변에 대한 사전 대응방안뿐 아니라 재난재해 위기 시 및 복구 중에도 도시의 기능을 유지하도록 하는 사후 회복과 안정성 방안을 제안하고자 한다. 연구방법: 기술적 관점과 사회적 관점에서 리질리언스 이론을 살펴보고 네덜란드의 리질리언트 정책과 전략을 통해 워터프론트 공간의 리질리언트 계획방안을 모색한다. 연구결과: 기후변화로 인한 해수면 상승과 홍수에 유연하게 대응하기 위한 지역 특성에 따른 예방계획 및 재해 후 도시기능 유지방안과 재해재난 위험을 고려한 공간계획 수립 및 홍수위험수준을 고려한 계획방안은 워터프론트 이용을 위한 토지이용과 사회적 성장 동반, 지역특성을 고려한 재난재해 취약성을 고려한 계획, 재난재해위험을 고려한 물관리 계획 등이다. 결론: 도시공간을 창출함에 있어 기존의 공간계획방식을 넘어 이상기후에 대응한 새로운 도시개발방식이 필요하며, 특히 기후변화에 가장 취약한 워터프론트의 공간적 특성에 따른 리질리언스 전략이 요구된다.

여중생의 체형인식 개선을 위한 영양교육 프로그램 개발(I);여중생의 체형인식에 따른 문제점 분석 (The Development of Nutrition Education Program for Improvement of Body Perception of Middle School Girls (I);The Analysis of Problems According to the Body Perception of Middle School Girls)

  • 소혜경;이은주;최봉순
    • 한국식생활문화학회지
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    • 제23권3호
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    • pp.403-409
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    • 2008
  • Recently, the desire for low body weight, which is an abnormal weight construct along with obesity, has become an evident and serious problem in teenagers. In Korea, the desire for low weight is not perceived as an important problem, but it is rapidly expanding relative to the physical changes and developmental issues teenagers experience. The social atmosphere presented through mass media is the key influencer for the increasing low weight occurrence in teenagers. Because thoughts about beauty have changed among people, and since there is apparent blind interest in slim body shape and appearance, already low-weight individuals are attempting to lose weight along with obese persons. Thus, we consider it necessary to guide teenagers toward having correct perceptions with regard to weight and their own body shape, and that a healthy and appropriate weight is beautiful. Therefore, for this study, we investigated body perception, abnormal weight, attitude toward weight control, and factors related to eating behavior among teenage girls, who are considered the at risk group for overt body weight control behavior. Based on this, we have attempted to set in motion a systematic and active nutrition education program that will allow us to increase body satisfaction by educating on nutritional issues related to development, and ultimately, implant healthy body shape perceptions.

A novel PLL control method for robust three-phase thyristor converter under sag and notch conditions

  • Lee, Changhee;Yoo, Hyoyol
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2014년도 추계학술대회 논문집
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    • pp.87-88
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    • 2014
  • The paper presents a novel phase locked loop(PLL) control method for robust three-phase thyristor dual converters under sag, notch, and phase loss conditions. This method is applied to three line to line voltages of grid to derive three phase angle errors from three separated single-phase PLLs. They can substitute for abnormal phase to guarantee the synchronization in the various grid fault conditions. The performance of novel PLL with moving average method is verified through simulations.

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Cytoskeletal Alteration of Mammalian Oocytes During Meiotic Maturation, Fertilization and Parthenogenesis

  • 김남형
    • Clinical and Experimental Reproductive Medicine
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    • 제22권3호
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    • pp.253-258
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    • 1995
  • Microtubules and microfilaments are major cytoskeletal components in mammalian ova that provide the framework for chromosomal movement and cellular division. Extensive changes of cytoskeletal organization occur during maturation and fertilization. The changes in cytoskeletons are essential for the normal meiotic maturation and for the formation of the biparental diploid genome of the embryo, and thus are repeated at each cell cycle during embryonic development. Disturbance of the cytoskeletal organization could result in abnormal gamete development and early embryonic death.

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Complete trisomy 14 mosaicism: first live-born case in Korea

  • Hur, Yun Jung;Hwang, Taegyu
    • Clinical and Experimental Pediatrics
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    • 제55권10호
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    • pp.393-396
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    • 2012
  • Trisomy 14 mosaicism is a rare chromosome disorder characterized by delayed development, failure to thrive, and facial dysmorphism. Only approximately 30 trisomy 14 mosaicism cases have been reported in the literature because trisomy 14 is associated with early spontaneous abortion. We report a case of a 17-month-old girl with abnormal skin pigmentation, delayed development, facial dysmorphism, and failure to thrive with the 47,XX,+14/46,XX chromosome complement.

휴대형 전원 순단 시험 장치의 개발 (Development of Portable Power Interrupt Tester using Microcontroller)

  • 박찬원;노재관
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2003년도 학술회의 논문집 정보 및 제어부문 B
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    • pp.962-964
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    • 2003
  • In this paper, development of portable power interrupt tester to evaluate microprocessor based control circuits for an endurance under abnormal power source. 89C2051 micro-controller is performed to make power interrupt signal, and software controls peripheral hardwares and built-in functions. Experimental results of this study will offer a good application to electronic appliance maker as a test device of hardware and software debugging use.

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