• Journal of the Optical Society of Korea
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• 제14권4호
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• pp.424-430
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• 2010

In coherent anti-Stokes Raman scattering (CARS) microscopy reported until now, conventional microscope objectives are used, so that they are limited for introduction into a living body. Gradient-index (GRIN) rod lenses might be a solution for miniaturized microscope objectives for in-vivo CARS microscopy. However, due to the inherent large amount of chromatic aberration, GRIN rod lenses cannot be utilized for this purpose. CARS imaging catheter, composed of miniaturized microscope objective and fiber bundle, can be introduced into a living body for minimally invasive diagnosis. In order to design the catheter, we have to first investigate design requirements. And then, the optical design is processed with design strategies and intensive computing power to achieve the design requirements. We report the miniaturized objective lens system with diffraction-limited performance and completely corrected chromatic aberrations for an in-vivo CARS imaging catheter.

• Parasites, Hosts and Diseases
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• 제41권1호
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• pp.41-45
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• 2003

Effects of gamma irradiation on the worm survival and chromosomal aberration of Clonorchis sinensis were studied. The metacercariae irradiated with various amounts of gamma radiation (ranging from 5 Gy to 50 Gy) were fed to rats, and the effects were compared with those of non-irradiated controls. Recovery rates of adult worms in irradiated groups were reduced gradually as increasing of the irradiation doses. No worm was recovered from rats which were fed with 50 Gy irradiated metacercariae. The chromosome number was 2n = 56 in all worms from all experimental groups. However, the groups irradiated with 20 Gy, 25 Gy or 30 Gy showed variations in the chromosome number, depending on different cells in the same individual. Radiation doses used in this study did not appear to induce chromosome aberrations, however, irradiation with 30 Gy showed slightly reduced chromosome size.

• 천문학회보
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• 제43권1호
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• pp.68.3-68.3
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• 2018

The MATS (Mesosphere Airglow / Aerosol Tomography Spectroscopy) satellite is a Swedish scientific microsatellite which Kyung Hee University participates in developing. The limb telescope of the MATS satellite is designed with linear astigmatism-free off axis optical configuration which allows wide field of view ($5.67^{\circ}{\times}0.91^{\circ}$). Here we present the full-field optical performance test setup that consists of a point source, a collimator, the limb telescope and a CCD (Charged Coupled Device). The incidence angle of the collimator was carefully controlled by the rotary stage under the limb telescope. The imaging tests represent expected results without dominant aberrations.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제4권2호
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• pp.182-186
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• 2004

This paper describes an advanced compensation for non-linear functions designed to remove steering aberrations from phased array antennas. This system alters the steering command applied to the antenna in a way that the appropriate angle commands are given to the array steering software for the antenna to point to the desired position instead of squinting. Artificial neural networks are used to develop the inverse function necessary to correct the aberration. Also a straightforward antenna steering function is implemented with neural networks for the 9-term polynomials of forward steering function. In all cases the aberration is removed resulting in small RMS angular errors across the operational angle space when the actual antenna position is compared with the desired position. The use of neural network model provides a method of producing a non-linear system that can correct antenna performance and demonstrates the feasibility of generating an inverse steering algorithm.

• 한국광학회지
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• 제9권4호
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• pp.227-230
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• 1998

가우스 동 결상광학계에서 Strehl ratio(SR)를 구하였다. 광원의 파장이 0.365$\mu\textrm{m}$, 광학계의 조리개수(NA)가 0.5이고 상의 분해 선폭이 0.5$\mu\textrm{m}$일 때 자오면에 비점수차가 있는 가우스 결상광학계와 일정한 진폭의 Rayleigh 동 광학계에서 SR을 이론적으로 구하여 비점수차의 Marechal 한계값을 비교한 결과 각각 0.65$\lambda$와 0.24$\lambda$를 얻었다. Seidel 제1차 수차에 대한 가우스 동과 Rayleigh 동의 Marechal 한계를 구한 결과 가우스 동의 Marechal 한계가 매우 큼을 알 수 있었다.

• Journal of Preventive Medicine and Public Health
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• 제17권1호
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• pp.245-250
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• 1984

Reciprocal exchanges of DNA in sister chromatids (SCEs) are induced by various carcinogens and mutagens, although the quantitative relationship between the number of mutations and SCEs induced varies among chemicals. Nevertheless, the analysis of SCEs production by various agents often proposed as a sensitive and quantitative assay for mutagenicity and cytotoxicity. Mercury, even if which has no evidences for mutagenicity and carcinogenicity, is reported to exert some cytotoxic effects, such as chromosomal aberrations or bad influences to ovulation and reproduction in experimental animals, etc.. In this study, tests for sister chromatid exchanges have been carried out on normal human lymphocytes in whole blood culture to add mercury chloride ($HgCl_2$) or methylmercury chloride ($CH_3\;HgCl$) for 72 hr. The results indicate the dose-dependent relationship between the frequencies of SCEs and the concentrations of $HgCl_2,\;CH_{3}HgCl$ and 5-bromo-2'-deoxyuridine (BrdU). Lymphocyte proliferation has depressed in the higher concentration of mercury.

• 한국광학회지
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• 제9권6호
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• pp.396-402
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• 1998

광학계의 결상성능평가는 optical transfer function(OTF)을 측정하는 것이 표준적인 방법으로 사용되고 있다. 그러나, 대량 생산되는 광학계의 경우에서는 측정의 편리함 때문에 test pattern을 투영하여 contrast를 검사하는 방법도 많이 사용되고 있다. 본 연구에서는 회절결상이론을 사용하여 주기적 line-space pattern에 대한 contrast transfer function(CTF)을 계산하는 프로그램을 개발하고, C­계수와 Zernike 다항식으로 표현되는 3차 파면수차에 의한 광학계의 modulation transfer function (MTF)과 CTF 변화를 비교, 분석하였다.

• Journal of the Optical Society of Korea
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• 제13권4호
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• pp.451-455
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• 2009

We present a numerical procedure that compensates for tilt phase aberration in in-line digital holography by computing the period of interference patterns in the reconstructed phase image. This method enables the reconstruction of correct and accurate phase information, even if strong tilt aberrations exist. Example applications of tilt aberration compensation are shown for a tilted plate, a micro-lens array, and a thin film transistor. This method is convenient because it uses only one hologram and no hardware to minimize the tilt aberration.

• Journal of the Optical Society of Korea
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• 제20권3호
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• pp.413-426
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• 2016

There has been much advancement in the field of aerial cameras for geographical features with the help of drones, image processing power and computer aided optical programs. In this study, we propose a new optical lens design technique which minimizes the amount of ‘the third order Seidel aberration’ for enhancing MTF. In addition, we suggest a new optical lens design which stabilizes the mass-production yield through R.S.M and has robustness secure through the Taguchi method. Eventually, the image processing algorithm of stereo matching is implemented in order to evaluate whether the proposed lens design result meets adequate specifications for the use of dual aerial photographs or not. This paper provides good guidance for the optical design by development of experiments.

• Journal of Plant Biology
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• 제38권4호
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• pp.321-328
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• 1995

Calli obtained from basal disc explants of Allium victorialis var.platyphyllum wre grown in three kinds of nutrient media (MS, BDS, and B5), and the frequencies of mitotic index and the chromosomal aberrations were analysed. The mitotic index varied from 0.55% to 1.01% with respect to culture media and ages. The mitotic irregularities like micro-, bi- and multi-nuclei, chromosome bridge and laggards were noted in each types of calli. The chromosome number variations observed in metaphase stage were identified aneuploid and tetraploid. Structural variations such as dicentric chromosomes, centromere breakage and small chromosomes were observed. Relationship between basal medium and chromosomal variability was not observed in this study. But, in BDS medium, NAA and BA had a more effect on number variation than kinetin.