• 재활복지공학회논문지
• /
• 제11권3호
• /
• pp.239-245
• /
• 2017

본 연구는 비만 청소년기 남성을 대상으로 복부지방면적과 피하지방두께, 신체둘레, 신체구성, 혈중 지질 간의 상관관계를 분석하였으며 주요 결과는 다음과 같다. 첫째, 복부지방면적과 피하지방두께 간의 관련성과 관련하여 전체지방면적과 피하지방면적은 피하지방두께를 구성하는 대부분의 변인과 관련성이 있었으며 특히 견갑골 아래 피부두께는 전체지방면적을 포한한 피하지방면적과 관련성이 높은 것으로 나타났다. 반면 피하지방 두께 변인들 중 가슴 부위 피하지방두께는 내장지방면적을 예측할 수 있는 유일한 변수로 조사되었다. 둘째, 신체둘레 및 신체구성 변수는 내장지방면적과는 상관관계가 없었으나 전체 및 피하지방면적과 관련성이 높은 것으로 나타났다. 신체둘레와 전체 및 피하지방면적과의 관련성에 있어서 허리둘레는 엉덩이 둘레 및 허리와 엉덩이 둘레를 더한 값보다 상관계수가 높게 나타났다. 또한 전체 및 피하지방면적의 예측에 있어서 체지방량은 체지방율 및 근육량 보다 관련성이 높은 것으로 나타났다. 셋째, 혈중 중성지방과 수축기 혈압은 각각 내장지방면적 및 피하지방면적을 예측할 수 있는 유일한 변수로 조사되었다.

• 대한영양사협회학술지
• /
• 제8권2호
• /
• pp.175-184
• /
• 2002

This study is to investigate consequent nutrient intake status, influence of body mass index(BMI), and fat distribution on the silk amino peptide(SAP) and dietary fiber supplementation. During 2 months of this research (January to March, 2002), 45 women aged 20yr – 30yr (average age 24.6yr) were selected as subjects. Nutrient intake was investigated by questionnaire, 24-hr recall method. Antropometric assessments of the subjects were investigated by SBIA method(Segmental bioimpedance assay, In body 3.0). The results are as follows: mean body weight 57.7kg, mean body height 161.9cm mean BMI 22.0, and mean food habit score was 8.47. Defecation frequency was increased by dietary fiber supplementation. Frequency of pain during defecation was significantly decreased by dietary fiber supplementation (p<0.01). Feeling of residual feces was significantly improved by dietary fiber supplementation(p<0.001). Status of energy and carbohydrate intakes significantly decreased after dietary fiber supplementation(P<0.05). Body fat and WHR(waist hip ratio) significantly decreased after dietary fiber supplementation(P<0.001), and percent body fat was decreased by dietary fiber supplementation, significantly(P<0.05). Above results of this study show that dietary fiber-added routine diet improves defecation condition, and lessens body fat, percent body fat without losing body muscle. Especially, declination of abdominal fat and WHR were notable. That meant decreased risk factor.

• Journal of Veterinary Science
• /
• 제23권6호
• /
• pp.70.1-70.13
• /
• 2022

Background: Fat stranding is a non-specific finding of an increased fat attenuation on computed tomography (CT) images. Fat stranding is used for detecting the underlying lesion in humans. Objectives: To assess the clinical significance of fat stranding on CT images for identifying the underlying cause in dogs and cats. Methods: In this retrospective study, the incidence, location, extent, distribution, and pattern of fat stranding were assessed on CT studies obtained from 134 cases. Results: Fat stranding was found in 38% (51/134) of all cases and in 35% (37/107) of tumors, which was significantly higher in malignant tumors (44%) than benign tumors (12%). Moreover, fat stranding was found in more than two areas in malignant tumors (16/33) and in a single area in benign tumors (4/4). In inflammation, fat stranding was demonstrated in 54% (7/13) in a single area (7/7) as a focal distribution (6/7). In trauma, fat stranding was revealed in 50% (7/14) and most were in multiple areas (6/7). Regardless of the etiologies, fat stranding was always around the underlying lesion and a reticular pattern was the most common presentation. Logistic regression analysis revealed that multiple areas (p = 0.040) of fat stranding and a reticulonodular pattern (p = 0.022) are the significant predictors of malignant tumor. Conclusions: These findings indicated that CT fat stranding can be used as a clue for identifying the underlying lesion and can be useful for narrowing the differential list based on the extent and pattern.

• Journal of Applied Biological Chemistry
• /
• 제66권
• /
• pp.328-337
• /
• 2023

We investigated the effects of single and combined administrations of Lactobacillus species (L. plantarum, LP; L. gasseri, LG; L. casei, LC) on blood lipid metabolism and obesity in mice fed a high-fat diet (HFD). The mice were continuously supplemented with LP, LP/LG, or LP/LG/LC, along with HFD, for 12 weeks. The consumption of HFD led to significant increases in body weight, total cholesterol, and triglyceride levels compared to the normal control group. However, administration of LP, LP/LG, or LP/LG/LC to HFD-fed mice reduced body weight gain and showed a tendency to suppress the levels of total cholesterol, triglycerides, and LDL-cholesterol, while increasing HDL-cholesterol levels. The HFD group exhibited increased abdominal fat weight and larger adipocytes in the epididymal adipose tissue compared to the NC group. However, the administered probiotics led to a significant reduction in adipocyte size with decreasing tendency in abdominal fat weight compared with the HFD group. Additionally, the deposition of giant vesicular fat cells in the liver of the HFD group considerably decreased in the probiotic-administered group. Microbiome analysis revealed an imbalance in intestinal microbes in the HFD group, characterized by lower Bacteroidetes and higher Proteobacteria ratios. However, probiotic administration tended to restore the microbial distribution by controlling the abundance of Bacteroidetes and Proteobacteria, resulting in decreased Firmicutes/Bacteroidetes and Proteobacteria/Bacteroidetes ratios. These results suggest that single and combined administration of LP and other probiotics holds enormous potential in reducing obesity in HFD-fed mice as they regulate lipid metabolism, reduce adipocyte size, and restore the balance of intestinal microbes.

• Archives of Plastic Surgery
• /
• 제37권5호
• /
• pp.535-546
• /
• 2010

Purpose: The subcutaneous fat tissue is separated into 2 layers by the subcutaneous fascia: the superficial and deep fat layers. The two fat layers have different structures according to the body regions. The purpose of this study is to evaluate the distribution and pattern of the two fat layers in the human body by computed tomography (CT) and histological analysis according to age, sex, anatomical region, and body mass index (BMI). Methods: This study included 200 males and 200 females who underwent 64-channel dynamic CT in our hospital. The patients were divided into 5 groups according to 10 years of their ages separately in either male or female gender. The thickness of the superficial and deep fat layers was measured in the abdominal, pelvic, and femoral regions, and we analyzed the values. Statistical analyses were performed using SPSS software. The $3{\times}3$-cm whole fat layers were harvested from the same sites of 3 cadavers for histological examination, and one cadaver was dissected for gross evaluation. Results: The total thickness of subcutaneous fat tissue was greater in females than in males, and the ratio of the superficial fat layer to the whole fat layer was higher in females. The superficial fat layer became thinner with increasing age in males. As BMI increased, the total fat layer became thicker, and the superficial fat layer became thicker than the deep fat layer. On histological examination, the superficial fat layer had small adipose lobules and showed a densely distributed pattern in the abdominal region, whereas in the femoral region, it had large adipose lobules and showed a sparsely distributed pattern. There were no significant differences in the histological findings of the deep fat layer between the 3 body regions. Conclusion: Significant differences in histological findings of the two fat layers were found in relation to age, sex, anatomical region, and BMI. The superficial fat layer became thinner with increasing age in males, but it was constant in females. As BMI increased, the total thickness of subcutaneous fat tissue became greater, and the superficial fat layer became thicker than the deep fat layer. Our measurements can be used to understand the characteristics of the fat layers in relation to age, sex, anatomical region, and BMI.

• Journal of Nutrition and Health
• /
• 제26권1호
• /
• pp.47-55
• /
• 1993

To investigate the effects of exercise-training on serum lipids, fat distribution and several parameters of body fatness(percent body fat, skinfolds thickness, body circumference) were assessed in 24 healthy male subjects submitted to an 8-wk high intensive exercise-training. Blood sample was taken twice, per and post exercise-training, Exercise-training took place 5 days a week and daily energy intake and expenditure were observed. The results obtained are summarized as follows: 1) Through exercise-training body weight (changes : 1.1$\pm$1.1kg ; p=0.000) and percent body fat (changes : 2.4$\pm$1.3% ; p=0.000) decreased significantly . 2) Suprailiac was the most reduced site by exercise-training among eight site skinfolds. Central skinfolds were changed more by exercise-training than peripheral skinfolds with reduction of 1.7$\pm$1.7mm and 0.2$\pm$1.9mm. Central site circumferences were reduced more by exercise-training than peripheral site circumferences. 3) Total cholesterol, HDL-cholesterol and LDL-cholesterol were not significantly changed by exercise-training while only triglyceride decreased (changes : 20.7$\pm$44.8mg/dl ; p<0.05). Changes in body weight were grately related to changes in total cholesterol. Changes in deep abdominal adipose tissue were related to changes in triglyceride.

• Journal of Nutrition and Health
• /
• 제40권7호
• /
• pp.630-638
• /
• 2007

This study was performed to examine the combined effects of L-carnitine and isoflavone supplementation on weight reduction and body fat distribution in overweight women. Overweight/obese women (body mass index > $23kg/m^2$) who were not diagnosed any type of diseases were included in this study and sixty subjects ($41.1{\pm}1.5$ years, $25.9{\pm}0.3kg/m^2)$ were randomly assigned to a placebo (n=30) or a supplement group (n=30, L-carnitine 300 mg+isoflavone 40 mg/day). We measured anthropometric parameters, abdominal fat distribution by computerizd tomography and blood components before and after the 12 week intervention period. After the 12 weeks of supplementation, subjects in L-carnitine and isoflavone supplement group showed a significant reduction of body weight (p < 0.001), body fat % (p < 0.05), and waist to hip ratio (p < 0.01) whereas placebo group did not show any changes. In a CT-scanned results, total fat area at L4 level was significantly reduced by 8.1% (p < 0.01) with the reduction of visceral fat area (-11.1%, p < 0.001) and subcutaneous fat area (-7.0%, p < 0.05) in the supplement group. The supplementation of L-carnitine and isoflavone showed the significant improvement of HDL-C (p < 0.01) and apoB (p < 0.05) concentrations, however, change values in those markers were not significant compared with those of the placebo group. In addition, a significant increase of adiponectin level (p<0.001) was observed in the supplement group after the intervention. The result of present study demonstrated that supplementation of 300 mg L-carnitine and 40 mg isoflavone per day fur 12 weeks can give beneficial effects on weight reduction and visceral fat accumulation. These potential antiobesity supplement can produce more favorable effects when combined with lifestyle modification.

• Nutritional Sciences
• /
• 제5권1호
• /
• pp.13-19
• /
• 2002

A mutation in the promoter region of uncoupling protein 3 (UCF3), specifically the -55C longrightarrow T transition, may influence an individual's energy metabolism and body weight. The objective of this study was to investigate the effect of a weight reduction program on endocrine functions and body fat distribution, related to UCP3 promoter genotype. Ninety overweight pre-menopausal female subjects participated in the weight reduction program at Yonsei University Hospital, and were placed on a calorie-restricted diet (300 kcal less than their daily requirements) for 12 weeks. After 12 weeks, all subjects on the program lost approximately 5% of their initial body weights and had lower Body Mass Index (BMI) values. Among the 90 women, 56 had a normal (without mutation) UCP3 genotype, while 34 women had mutations in the promoter region of UCP3. Despite similar weight reductions in both groups, a significantly higher decrease in abdominal adipose tissue was observed in the normal UCP3 genotype group, compared to the group with mutations. In particular, there was a significant reduction of fat at the lumbar 1 (Ll) level in the without-mutation group. Serum levels of total cholesterol, apolipoprotein Al were significantly decreased in the without-mutation group, by 4.4% and 5.7% respectively. Serum levels of hormones were not significantly changed in both groups artier the intervention. However, in the group without the mutations, the leptin level significantly reduced by 23.4% (p<0.001). Serum free fatty acid (FFA) concentration was significantly increased in the group with mutation following the weight reduction program. On the other hand, FFA responses were shown similar increases in both groups. In conclusion, although no difference was found in the magnitude of weight reduction in both groups, there were significant differences in body fat distribution and in endocrine function between the groups.

• Tuberculosis and Respiratory Diseases
• /
• 제49권4호
• /
• pp.495-501
• /
• 2000

배경 : 운동부하심폐기능검사는 운동 장애의 조기진단과 환자의 심폐 예비능력을 측정할 수 있는 유용한 방법이다. 또한 비만이 최대운동의 제한인자로 작용함이 알려져 있다. 따라서 본 연구에서는 운동부하심폐기능검사와 체성분분석기를 통하여 비만과 비만의 부위가 최대 운동능력에 미치는 영향을 살펴보고자 하였다. 방법 : 건강한 자원자 42명을 대상으로 하여 체성분분석기 Inbody 2.0 (Biospace Co)와 bicycle ergometer 2900 model(Sensormedic Co, USA)을 이용하여 체생분분석과 운동부하심폐기능검사를 시행하였다. 결과 : 전체 대상군에서 $VO_2$max/min/kg은 비만도와 의미있는 역상관관계를 보였고, 체지방율과도 통계적으로 의미있는 역상관관계를 보였다. 전체 대상군에서는 $VO_2$max/min/kg이 복부지방률과 통계적으로 유의한 상관관계를 보이지 않았지만, 남자대상군에서는 $VO_2$max/min/kg와 복부지방률이 통계적으로 유의한 역상관관계를 보였다. 결론 : 비만이 운동에 제한인자로 작용한다는 것을 확인하였고, 남자에서는 비만 중에는 특히 북부미만이 운동능력에 제한적인 영향을 미친다는 사실을 확인하였다. 여성 대상자에서는 복부비만의 기준을 만족하는 대상자가 적어서 복부비만의 영향평가가 어려웠다. 이상의 결과로 임상에서 운동부하심폐기능검사 결과 판독시에는 비만과 비만부위에 의한 영향을 고려하는 것이 필요할 것으로 판단된다.

• 비만대사연구학술지
• /
• 제2권1호
• /
• pp.25-28
• /
• 2023

Early evaluation of obesity is important. Obesity is defined as an excessive accumulation of fat that causes harm to health. Among patients who visit a hospital for weight-related issues, diseases other than body fat gain may be present; however, people often cannot distinguish between these issues and concerns. Therefore, among patients who visit the hospital with weight gain concerns, it is necessary to determine whether the weight gain is actually the result of excessive fat accumulation. After being diagnosed with obesity, the cause and degree of obesity, the amount and distribution of body fat, and the degree of risk should be evaluated. Additionally, obesity-related complications should be identified and, even if there are no complications, all related risk factors should be evaluated and managed. In all these processes, diagnostic methods such as history taking, physical examination, body fat measurement, blood tests, and imaging tests are necessary, but history taking and physical examination, which can provide a lot of information from the beginning, should not be overlooked.