• 제목/요약/키워드: aPTT

검색결과 247건 처리시간 0.02초

반복자연유산 환자에서 Antithrombin III 결핍증에 대한 연구 (The Study of Antithrombin III Deficiency in Patients with Recurrent Spontaneous Abortion)

  • 남윤성;차광렬;김남근;강명서;오도연
    • Clinical and Experimental Reproductive Medicine
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    • 제28권4호
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    • pp.301-305
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    • 2001
  • Objective : To analyze the antithrombin II deficiency in patients with recurrent spontaneous abortion. Material and Method: The blood samples were tested by chromogenic assay to evaluate the activity of antithrombin III. Results: There was only one case of antithrombin III deficiency. This patient experienced one neonatal death after delivery and one FDIU (fetal death in utero). And also this patient showed a lupus anticoagulant and the prolongation of PTT. Conclusions: Women with recurrent miscarriage who have no obvious identified cause should consider hematologic screening. Antithrombin III deficiency could be a cause of recurrent spontaneous abortion. But the incidence is very rare in Korean patients.

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해상 LNG 인수시설 대구경 강관말뚝 시공 사례 연구 (A Case Study of large diameter steel pipe pile Foundation for Offshore LNG Facility)

  • 류대영;김형욱;장우영;최기병;조성한
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2010년도 춘계 학술발표회
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    • pp.70-77
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    • 2010
  • In this paper, a case study of drivability and bearing capacity of large diameter steel pipe piles at PTT LNG site in Thailand is introduced. The LNG facilities were designed to be founded on steel pipe pile foundations driven into the weathered rock formation overlaid by sand layers. The drivability analyses of open ended pipe piles were carried out using GRL WEAP program and the bearing capacities of the piles were estimated. Dynamic load tests were performed to evaluate end bearing resistance, and it is shown that the measured end bearing resistance is smaller than the calculated end bearing because the plugging does not develop sufficiently in case of large diameter pipe piles.

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데이터 추출 과정을 적용한 Block-wise Adaptive Predictive PLS (Block-wise Adaptive Predictive PLS using Block-wise Data Extraction)

  • 김성영;정창복;최수형;이범석
    • 제어로봇시스템학회논문지
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    • 제12권7호
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    • pp.706-712
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    • 2006
  • Recursive Partial Least Squares(RPLS) method has been used for processing the on-line available multivariate chemical process data and modeling adaptive prediction model for process changes. However, RPLS method is unstable in PLS model updating because RPLS method updates PLS model by merging past PLS model and new data. In this study, Adaptive Predictive Partial Least Squres(APPLS) method is suggested for more sensitive adaptation to process changes. By expanding APPLS method, block-wise Adaptive Predictive Partial Least Squares(block-wise APPLS) method is suggested for a lager scale data of chemical processes. APPLS method has been applied to predict the reactor properties and the product quality of a direct esterification reactor for polyethylene terephthalate(PTT), and block-wise APPLS method has been applied to predict the cetane number using NIR Diesel Spectra data. APPLS and block-wise APPLS methods show better prediction and updating performance than RPLS method.

The Effect of K Promoter on Ni-Co (Bimetallic) Catalyst for Dry Methane Reforming

  • Dharmasaroja, Nichthima;Phongaksorn, Monrudee;Tungkamani, Sabaithip;Ratana, Tanakorn;Sornchammi, Thana
    • International Journal of Advanced Culture Technology
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    • 제3권2호
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    • pp.110-117
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    • 2015
  • 10 wt% (Ni-Co) catalysts with different Ni and Co content : 10%Ni, 9%Ni1%Co, 7%Ni3%Co, 5%Ni5%Co, 3%Ni7%Co, and 10%Co; were prepared using sol-gel method followed by incipient wetness impregnation method. To investigate the catalytic activity including the stability, dry methane reforming were demonstrated over the pelletized catalysts at $620^{\circ}C$ under atmospheric pressure in a $CH_4:CO_2:N_2$ feedstock for 360 min. The results showed that bimetallic catalysts with the Co content equal to or greater than 3% were more stable than monometallic catalysts (10%Ni and 10%Co). The temperature programmed hydrogenation interpreted that the additional of Co into Ni catalyst improved the carbon resistance from methane cracking. Promoted this type of bimetallic catalyst using 1wt% K (trimetallic catalyst) prevented the carbon formation on the catalyst. The temperature programmed desorption of $CO_2$ indicated that this trimetallic catalyst has a greater number of strong basic sites. Moreover, the appearance of K lowered the number of weak basic sites and decreased the conversion of methane by 12 %.

900MHz대 FDD방식을 이용한 선내용 Tranceiver에 관한 연구 (A Study on the 900MHz FDD Tranceiver for the Vessel)

  • 송면규;조학현;김정년
    • 한국정보통신학회논문지
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    • 제2권3호
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    • pp.359-365
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    • 1998
  • The portable two way radio telephone amongst GMDSS equipment in the vessel is very important portable wireless one for search and rescue in distress situation. Although the portable two way radio telephone must be equipped with in the vessel by IMO & RR, other kinds of wireless tranceivers are widely used to communicate with crew members who are separately appointed at bridge forecastle and poop in leaving or arriving at the port, passing through a narrow canal or voyaging in the foggy weather, Most of those wireless tranceivers except portable two way radio telephone are allocated at 27MHz band with PTT simplex system that makes crew members difficult to work effectively in the vessel. In this research 900MHz band FDD(frequency duplex division) tranceiver system is studied to help crew members in the vessel to communicate with themselves freely and to work easily meanwhile with simple operation. 900MHz band FDD tranceiver system uses one chip FM frontend IC to realize the miniaturization and downsizing of tranceiver and small size head set attached to helmet. The credibility of this research's result is highly evaluated by circuit analysis with computer aided simulation, and partly modified 900MHz band cordless phone circuit.

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900MHz대 FDD 방식을 이용한 선내용 Tranceiver에 관한 연구 (A Study on the 900MHz FDD Tranceiver for the Vessel)

  • 김정년;조학현;송면규;김기문
    • 한국정보통신학회:학술대회논문집
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    • 한국해양정보통신학회 1998년도 춘계종합학술대회
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    • pp.365-370
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    • 1998
  • The portable two way radio telephone amongst GMDSS equipment in the vessel is very important portable wireless one for search and rescue in distress situation. Although the portable two way radio telephone must be equipped with in the vessel by IMO RR, other kinds of wireless tranceivers are widely used to communicate with crew members who are separately appointed at bridge forecastle and poop in leaving or arriving at the port, passing through a narrow canal or voyaging in the foggy weather. Most of those wireless tranceivers except portable two way radio telephone are allocated at 27MHz band with PTT simplex system that makes crew members difficult to work effectively in the vessel. In this research 900MHz band FDD(frequency duplex division) tranceiver system is studied to help crew members in the vessel to communicate with themselves freely and to work easily meanwhile with simple operation. 900MHz band FDD tranceiver system uses one chip FM frontend IC to realize the miniaturization and downsizing of tranceiver and small size head set attached to helmet. The credibility of this research's result is highly evaluated by circuit analysis with computer aided simulation. and partly modified 900MHz band cordless phone circuit.

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헤파린 기인성 혈소판감소증 환자에서의 개심술 (Open Heart Surgery in Patient with Heparin- Induced Thrombocytopenia)

  • 송석원;홍유선;곽영란;안신기
    • Journal of Chest Surgery
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    • 제35권6호
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    • pp.475-478
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    • 2002
  • 42세 남자환자가 내원 3개월전부터의 호흡곤란, 복부팽만 및 식욕부진으로 내원하였다. 이학적 검사상 심잡음이 청진되어 심초음파를 시행한 결과, 좌심방 혈전을 동반한 승모판협착증 및 삼첨판폐쇄부전이 진단되어 수술전 헤파린 지속 주입을 시작하였다. 내원 11일째 혈소판수치가 감소하여 시행한 항체검사 및 혈소판응괴능 검사에서 음성이 나왔지만 임상적으로 헤파린 기인성 혈소판감소증을 진단하였다. 수술중 심폐우회술시 헤파린 대체약물인 히루딘(hirudin)을 사용하였으며, ACT, aPTT를 측정하며 수술대에서 육안적으로 혈전형성여부를 확인함으로써 성공적으로 수술을 하였다, 수술 중 및 수술 후 헤파린 접촉은 없었으며, 수술 후 과다 출혈 및 전신적 혈전색전증 등의 합병증은 발생하지 않았다.

腦硬塞 患者에서 銀杏葉椎出物의 治療效果 (Effect of Ginkgo biloba extract in treatment of cerebral infarction)

  • 박양춘;임석린;김병탁
    • 한방안이비인후피부과학회지
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    • 제11권1호
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    • pp.240-250
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    • 1998
  • Background: Ginkgo biloba extract is used in disorser of cerebral and peripheral blood circulation, dysfunction of brain, atherosclerosis etc., but there are little study about GbE in oriental medicine. We wished to assessthe efficacy of GbE for the treatment of cerebral infarction Method : The study group comprised 40 patients who arrived at hospital during 48 hours after attack. All patient were devided into two group. The control group was treated with Uhuangcheongsimhuan, Seonghyangjeonggisan, acupuncture therapy only, while the GbE group was treated with above therapy plus 5 days of administration of GbE(40mg three times per day). Result: 1. Symptom improve scores did not showed significant difference between control and GbE group. 2. Vasoreactivity of carotid siphon increased significantly in GbE group after treatment (in the left only : p<0.05). 3. Vasorcactivity of radial artery increased significantly in GbE group after treatment(in the right only ; p<0.05). 4. PT, a-PTT, Fibrinogen did not showed significant changes between before and after treatment in both group. Conclusion: These findings suggest that vasoreactivity increasing effect of GbE may be useful in the prevention and treatment of cerebral infarction. But the vasoreactivity increasing effect of GbE may be different from symptom imroving.

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약용 및 야생식물로부터 트롬빈 저해물질의 탐색 (Screening of Thrombin Inhibitors from Medicinal and Wild Plants)

  • 권윤숙;김영숙;권하영;권기석;김경재;권정숙;손건호;손호용
    • 생약학회지
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    • 제35권1호통권136호
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    • pp.52-61
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    • 2004
  • Inhibitory activities of 264 methanol extracts, which were prepared from different parts of 210 kinds of wild and medicinal plants, against human thrombin were evaluated. Based on the anti-coagulation activity determined by thrombin time and activated partial thromboplastin time, the 14 extracts were screened. The fibrinolytic activity, heat stability and inhibition of other proteolytic digestive enzymes, such as pepsin, papain, trypsin and chymotrypsin, of the 14 extracts were further determined, and Ginko biloba (herba), Ephedra sinica (radix), Reynoutria elliptica (herba), Amomum tsao-ko Crevost (fructus), and Magnolia officinalis Rehd. et Wils (bark) were finally selected as possible plant sources for anti-thrombosis agent. These results suggested that medicinal and wild plants could be the potential source of thrombin inhibitor.

인지과제 수행시 배경 소음의 크기에 따른 생리적 반응차 (The role background noise intensity on Physiological activity during performance of mental task)

  • 손진훈;;민윤기;이경화;최상섭
    • 한국음향학회:학술대회논문집
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    • 한국음향학회 1999년도 학술발표대회 논문집 제18권 1호
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    • pp.269-273
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    • 1999
  • Combination of mental stress task with noise background is a traditional tool employed in psychophysiology. However, intensity of background noise is a factor affecting both performance on test and psychophysiological responses associated with stress evoked by mental load in noisy environment. In the current study on 7 subjects we analyzed the influence of white noise (WN) intensity (55, 70, and 85 dB[A] ) on psychophysiological responses during word recognition test performed on noise background. There were recorded following physiological variables: electrodermal activity (EDA) , namely, skin conductance level (SCL), skin conductance response (SCR) amplitude (SCR-A), rise time and total number of SCRs (N-SCR); cardiovascular activity, e.g., heart rate (HR), respiratory sinus arrhythmia (RSA) index, pulse transit time (PTT), finger pulse volume (PV), skin temperature (SKT) and respiratory activity, such as respiration rate (RESP-R) and inspiration wane amplitude (RESP-A) during baseline resting state and 40 s long performance on 3 similar Korean word recognition tests with different WN intensity (55, 70, and 85 dB). Electrodermal responses (SCR-A, SCL, N-SCR) demonstrated gradual increment with increased intensity of noise, and this increase of response magnitude with higher intensity of noise was typical also for r skin temperature (phasic SKT decrease) and pulse volume (phasic and tonic PV decrease). However, some cardiovascular and respiratory responses did not exhibit same tendency of gradual increase of reactivity , namely HR, as well as RESP-R and RESP-A showed decrement of response magnitudes. Important finding in terms of cardiovascular reactivity was that 55 and 70dB evoked similar profiles, while 85dB WN resulted in significantly different profile of reactions, suggesting that there exists a threshold level after which intensive auditory stimulation elicits psychophyslological responses pattern of different quality. There are discussed potential autonomic mechanism involved in mediation of observed physiological responses.

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