• The Journal of Korean Association of Computer Education
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• v.10 no.5
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• pp.71-79
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• 2007

The purpose of this research is to show that elements of learning information's record(learning time and the score of practice test) have a significant effect on the correctness of decision when they are applied to e-Learning based on CAT with SPRT model. Especially, the score of practice test can be used in the real e-learning environment as its effect showed approximately 90% improvement. Therefore, if we apply learning information's record to SPRT in evaluation, we can evaluate the learner's ability more precisely and quickly, contributing to the enhancement of the individualization of learners. If an algorithm with variables from learning information's record can be developed, a better e-Learning evaluation program will be made in the future.

• Journal of Internet Computing and Services
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• v.23 no.3
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• pp.125-135
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• 2022

This study aims to explore variables using machine learning and provide analysis techniques suitable for predicting pharmacy sales whether government statistical indicators built to create an industrial ecosystem based on data, network, and artificial intelligence affect pharmacy sales. Therefore, this study explored predictive variables and performance through machine learning techniques such as Random Forest, XGBoost, LightGBM, and CatBoost using analysis data from January 2016 to December 2021 for 28 government statistical indicators and pharmacies in the retail sector. As a result of the analysis, economic sentiment index, economic accompanying index circulation change, and consumer sentiment index, which are economic indicators, were found to be important variables affecting pharmacy sales. As a result of examining the indicators MAE, MSE, and RMSE for regression performance, random forests showed the best performance than XGBoost, LightGBM, and CatBoost. Therefore, this study presented variables and optimal machine learning techniques that affect pharmacy sales based on machine learning results, and proposed several implications and follow-up studies.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.24 no.5
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• pp.273-288
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• 1991

To elucidate the physiological and biochemical differences between chondrichthyes and osteichthyes, the properties of the specific digestive enzymes in cat-shark, Cephaloscyllium umbratile, and mackerel, Scomber japonicus, were studied. Homogenous trypsin proved through the disc-electrophoresis, SDS-PAG electrophoresis and gel filtration was obtained from the pancreas of cat-shark by $50-70\%$ saturated ammonium sulphate fractionation, DEAE-Sephadex A-50 column chromatography, benzamidine-Sepharose 6B affinity chromatography and Sephadex G-75-120 gel filtration. Two types of trypsins were also obtained from the pyloric caeca of mackerel by $30-70\%$ saturated ammonium sulphate fractionation and the slightly modified procedure from the method adopted in the purification of cat-shark trypsin. The two trypsins, designated trypsin A and B, were proved their homogeneity by disc- and SDS-PAG electrophoresis and gel filtration. The molecular weights of the trypsins were estimated to be 31,700 for cat-shark trypsin, 30,000 for mackerel trypsin A and 29,000 for mackerel trypsin B by SDS-PAG electrophoresis, but those were estimated to be 21,500 for cat-shark trypsin, 23,700 for mackerel trypsin A and 21,500 for mackerel trypsin B by gel filtration. The trypsins exhibited their optimum conditions at pH 9.0 and on temperature ranged from $45^{\circ}C\;to\;50^{\circ}C$ for cat-shark, and at pH 8.0 and a temperature of $50^{\circ}C$ for mackerel trypsin A and B, respectively. The cat-shark trypsin was stable at pH 10.0 and the temperature below $10^{\circ}C$, whereas the mackerel trypsin A and B, were stable in the range over pH 7.0 to pH 9.0 below $10^{\circ}C$ and at pH 8.0 below $35^{\circ}C$, respectively. The mackerel trypsins were severely inhibited by some heavy metal ions such as $Ag^{2+},\;Cu^{2+}\;and\;Hg^{2+}$ compared to cat-shark trypsin. All of the enzymes were also inhibited by antipain, leupeptin, TLCK(tosyllysine chloromethyl ketone) and SBTI(soybean trypsin inhibitor) remarkably. The inhibitory effects of PMSF(phenylmethane sulphonylfluoride), DFP(diisopropyl fluorophosphate) and benzamidine were indicated that these enzymes belong to serine-proteases.

• Journal of Ginseng Research
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• v.25 no.4
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• pp.150-155
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• 2001

This study examined effects of the active ingredients from ginseng on paraquat(PQ) toxitity. Mice were given PQ(25mg/kg, ip) and then they were given total saponins (TS; 5mg/kg, orally), protopanaxadiol (PD; 5mg/kg, orally) and protopanaxatriol(PT; 5mg/kg, orally) per day for periods of 1,3 & 7 days. We measured the activities of superoxide dismutase (SOD), electrophoretic isozyme band, catalase (CAT) were compared in the liver of mouse that dose with PQ and/or TS, PD and PT. The activities of SOD, CAT were generally higher in PQ+PD group than others groups. Especially the activity of SOD was the highest in PQ+PD group than others groups. SOD isozyme separated into three bands by electrophoresis. One band was located to near the anode side and two bands were cathode side. As the results of treated with KCN, we were confiremed that the Cu, Zn-SOD was located to near the anode side but the Mn-SOD were cathode side. Our results suggested that an antioxidant effect of ginseng saponins elevated a protection ability to an oxidative damage by direct action of SOD, CAT and reinforced the synthetic ability of endogenous antioxidant material in living organism. Particularly, PD was a effective antioxidant compared with others.

• BMB Reports
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• v.44 no.10
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• pp.647-652
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• 2011

The protein transduction domains have been reported to have potential to deliver the exogenous molecules, including proteins, to living cells. However, poor transduction of proteins limits therapeutic application. In this study, we examined whether imipramine could stimulate the transduction efficiency of PEP-1 fused proteins into astrocytes. PEP-1-catalase (PEP-1-CAT) was transduced into astrocytes in a time- and dose-dependent manner, reducing cellular toxicity induced by $H_2O_2$. Additionally, the group of PEP-1-CAT + imipramine showed enhancement of transduction efficiency and therefore increased cellular viability than that of PEP-1-CAT alone. In the gerbil ischemia models, PEP-1-CAT displayed significant neuroprotection in the CA1 region of the hippocampus. Interestingly, PEP-1-CAT + imipramine prevented neuronal cell death and lipid peroxidation more markedly than PEP-1-CAT alone. Therefore, our results suggest that imipramine can be used as a drug to enhance the transduction of PEP-1 fusion proteins to cells or animals and their efficacies against various disorders.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.9
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• pp.1266-1271
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• 2022

Cats have strong wildness so they have a characteristic of hiding diseases well. The disease may have already worsened when the guardian finds out that the cat has a disease. It will be of great help in treating the cat's disease if the owner can recognize the cat's polydipsia, polyuria, and frequent urination more quickly. In this paper, 1) Efficient version of DeepLabCut for pose estimation, 2) YOLO v4 for object detection, 3) LSTM is used for behavior prediction, and 4) BoT-SORT is used for object tracking running on an artificial intelligence device. Using artificial intelligence technology, it predicts the cat's next, polyuria and frequency of urination through the analysis of the cat's behavior pattern from the home CCTV video and the weight sensor of the water bowl. And, through analysis of cat behavior patterns, we propose an application that reports disease prediction and abnormal behavior to the guardian and delivers it to the guardian's mobile and the server system.

• Journal of Veterinary Clinics
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• v.35 no.5
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• pp.237-239
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• 2018

A 2 months old female Korean domestic shorthair cat weighing 1.2 kg was come to hospital because of respiratory discomfort and lethargy. Heart sounds was more intense and clear on the right side than the left. On radiographic views, loss of the normal diaphragm line, undistinguishable shadow of heart, shadow of gas-containing intestines could be observed in thoracic cavity. Diaphragmatic herniorrhaphy was performed by using propofol 8 mg/kg IV and isoflurane without any complication. On 7th day after the operation, almost all the clinical signs and radiographs including diaphragmatic line, cardiac silhouette, liver and small intestines were turned to normal.

• Journal of Veterinary Clinics
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• v.18 no.4
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• pp.434-437
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• 2001

A female Russian blue cat has invited Animal Hospital because of diarrhea after the mating. The eggs on internal parasite and Giardia sp. were diagnosed in the feces floating test, and treated with metronidazole, pyrantel pamoate and antibiotics. There were no diarrheal sign in the reevaluation, but anorexia, polydipsia, polyuria, and vaginal discharge was newly induced. Streptococcus sp. was inspected by smearing of vaginal discharge, and enlarge-ment of uterus was evaluated by x-ray examination. This case was confirmed as pyometra and recovered by ovariohysterectomy on the basis of that examination. The rate of incidence in feline pyometra is not so high as in the canine.

• The Journal of Korea Robotics Society
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• v.7 no.3
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• pp.161-170
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• 2012

The Industrial Ethernet technology enables advanced control architectures and offers several advantages for high precision multiple motors actuation. This paper presents the implementation and analysis of a motor drive with EtherCAT, an industrial standard for real time Ethernet. Considering the characteristics of the implemented software and the network interface, the motion and time-response of motor actuation for the networked Mobile Inverted Pendulum have been analyzed. Using the analysis with the task execution times measured from the developed drive, the performance characteristics of the drive in respect of the maximum achievable throughput have been verified by comparing to the conventional RS232.

• Journal of Veterinary Clinics
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• v.25 no.6
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• pp.518-522
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• 2008

An approximately 8-month-old, 2.61 kg, male Siamese kitten was referred with primary complaints of a 1-week history of respiratory distress, exercise intolerance and dyspnea. Diagnostic studies identified III/VI systolic murmur in the cardiac auscultation, right ventricular enlargement patterns in the electrocardiogram, pleural effusion and right-sided cardiomegaly in the thoracic radiography, and right marked ventricular dilatation, right atrial enlargement, atrial septal defect and abnormal left atrium divided by fibromuscular membrane. Based on these findings, the case was diagnosed as cor triatriatum sinistrum complicated with an ostium primum atrial septal defect. The cat was rescued with furosemide, nitroglycerine, oxygen supplement and fluid removal from pleural cavity.