• 제목/요약/키워드: Zygomycetes

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Mucormycosis: A Case Report and Review of Literature

  • Lee, Guem-Sug;Lee, Kyung-Hwa;Kim, Byung-Gook;Im, Yeong-Gwan
    • Journal of Oral Medicine and Pain
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    • 제39권1호
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    • pp.29-33
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    • 2014
  • Mucormycosis is a rare but fatal fungal infection with low survival rate in immune-compromised patients. It is caused by a fungus belonging to the Mucoraceae family of the Zygomycetes class. Mucormycosis is classified as rhino-orbital-cerebral, pulmonary, cutaneous, gastrointestinal, disseminated, and miscellaneous types according to its clinical manifestations. Early diagnosis and treatment along with correction of the underlying medical condition is important for favorable results. This case presentation describes mucormycosis involving the anterior maxillary region in a leukemic patient with prolonged neutropenia. The patient benefited from a timely biopsy and immediate treatment with amphotericin B, and was successfully managed with an interdisciplinary team approach consisting of dental and several medical specialists.

Variation of Soil Mycoflora in Decomposition of Rice Stubble from Rice-wheat Cropping System

  • Vibha, Vibha;Sinha, Asha
    • Mycobiology
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    • 제35권4호
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    • pp.191-195
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    • 2007
  • The colonization pattern and extent of decay produced in paddy stubble by soil inhabiting mycoflora were done by using nylon net bag technique. Among the three methods used for isolation of fungi, dilution plate technique recorded the highest number of fungi followed by damp chamber and direct observation method. Nutrient availability and climatic conditions (temperature, humidity and rainfall) influenced the occurrence and colonization pattern of fungi. Maximum fungal population was recorded in October ($48.99{\times}10^4/g$ dry litter) and minimum in May ($11.41{\times}10^4/g$ dry litter). Distribution of Deuteromycetous fungi was more in comparison to Zygomycetes, oomycetes and ascomycetes. In the early stage of decomposition Mucor racemosus, Rhizopus nigricans, Chaetomium globosum and Gliocladium species were found primarly whereas at later stages of decomposition preponderance of Aspergillus candidus, Torula graminis, Cladosporiun cladosporioides and Aspergillus luchuensis was recorded.

국내 미기록 진딧물병원성 곰팡이 Neozygites fresenii에 관한 보고 (First Record of the Entomopathogenic Fungus Neozygites fresenii on the Aphid in Korea)

  • 윤철식;이민호;이승환;유재기;이정운
    • 한국균학회지
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    • 제27권1호통권88호
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    • pp.66-67
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    • 1999
  • 국내 미기록 진딧물병원성 곰팡이, Neozygites fresenii를 1998년 6월경 수원 농업과학기술원내의 망초에 서식하는 진딧물(Dactynotus sp.)에서 발견하였다. 이에 국내에서 처음으로 N. fresenii를 보고하며, 형태적 특성을 기재한다. 이 균은 짧은 papillar를 지닌 둥근 모양의 1차 포자를 형성하며, 1차 포자로부터 두 종류의 2차 분생자병을 형성하는 것이 가장 큰 특징이었다. 짧고 금은 2차 분생자병에서는 1차 포자와 유사한 2차 포자가 생성되었으며, 가늘고 긴 분생자병에서는 아몬드 모양의 포자가 형성되었다.

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닭에 있어서 Absidia corymbifera에 의한 폐렴 (Pulmonary Zygomycosis in Chicks due to Absidia corymbifera)

  • 팔 마헨드라;이창우
    • 한국임상수의학회지
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    • 제11권1호
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    • pp.339-341
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    • 1994
  • 45두의 브로일러 중 2두에서 배양과 직접 현미경 검사에 의해 폐 접합균증이 진단되었다. 폐의 병변부를 Sabouraud 배지에 접종하고 37$^{\circ}C$에서 배양하여 Absidia corymbifera가 분리되었다. 폐조직으로 squash표본을 만들어 직접 현미경 검사를 한 결과 폭이 넓고, 격벽이 없으며, 분지를 나타내는 접합균형 균사를 나타내었다. 감염된 폐조직의 PAS 염색 날인표본에서도 이와 비슷한 균요소가 발견되었다. 닭장의 흙과 닭똥으로부터 고농도의 A. corymbifera가 증명되었는데 이것은 이 브로일러균에서 환경이 감염원이었던 것을 제시하는 것으로 판단된다. 닭의 폐렴 감별진단에 있어서 접합균류도 고려할 것이 강력히 주장되었다.

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EFFECT OF MOLDY AND NONMOLDY WHEAT STRAW TREATED WITH OR WITHOUT AMMONIA ON PERFORMANCE AND BLOOD SERUM CONSTITUENTS IN STEERS

  • Khan, M.F.;Smith, G.S.
    • Asian-Australasian Journal of Animal Sciences
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    • 제7권3호
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    • pp.413-419
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    • 1994
  • Mold growth decreased nutritive value of wheat straw (WS). Mold increased DM (94 vs 98%) and ADF (51 vs 56%) contents and had no effect on natural detergent fiber (NDF). Crude protein and N values were decreased in moldy wheat straw, Mold increased insoluble N content of wheat straw (WS) from 21 to 27%. Ammoniation increased the CP of nonmoldy straw from 3.8 to 8.3% and moldy straw from (3.3 to 6.2%). Aspergillus and zygomycetes fungal species were most prevalent and total numbers were higher on moldy straw. Ammoniation decreased total numbers of fungal spores on nonmoldy and moldy WS. Ammoniation of moldy WS increased (p < 0.10) feed in take (1.8%) as compared with nonmoldy, ammoniated, nonmoldy and moldy WS. Steers fed moldy WS had lowest (p < 0.10) feed intake (1.3% of BW daily) compared with other diet. There was little difference (p < 0.10) in intake of nonammoniated vs. ammoniated WS. Steers fed moldy straw lost 6 kg BW. Ammoniated, nonmoldy straw elevated Blood Urea Nitrogen (BUN) (10.5 mg/dl). Alkaline Phosphatase (ALK) was greater in steers fed moldy VS nonmoldy straw (148 VS 95 U/liter. p < 0.10).

섬유소 가수분해효소와 Chitinase 처리에 의한 균류 원형질체 생성에 관한 연구 (Formation of Fungal Protoplast by the Reaction of Cell Wall Lytic Enzymes)

  • 오승희;장명호
    • 한국식품과학회지
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    • 제13권2호
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    • pp.101-106
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    • 1981
  • 균류의 세포벽은 복합 다당류의 매우 견고한 막으로 되어있기 때문에 균체의 이용이나 세포막 관련성 효소연구등에 직접적으로 방해가 되어왔기 때문에 이의 제거를 위해 본 실험에서는 Trichoderma viride $TO_4$ 균주에서 얻은 섬유소 가수분해효소와 토양에서 직접 분리한 Streptomyces sp. 115-5균주에서 얻은 chitinase를 혼용하여 각종 균사체에 작용시켜 세포벽의 제거정도에 따른 원형질체 생성을 균체별로 측정하여 그 결과를 얻었다. (1) Ascomycetes 류에서는 반응 3시간후 $3{\times}10^{7}$개의 원형질체가 생성되었다. (2) Zygomycetes류에서는 반응 3시간후 $9{\times}10^7$개의 원형질체가 생성 되었다. (3) 효모류는 이 혼합효소작용에 대하여 별다른 반응을 나타내지 않았다.

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Successful Treatment of a Case with Rhino-Orbital-Cerebral Mucormycosis by the Combination of Neurosurgical Intervention and the Sequential Use of Amphotericin Band Posaconazole

  • Yoon, Young-Kyung;Kim, Min-Ja;Chung, Yang-Gu;Shin, Il-Young
    • Journal of Korean Neurosurgical Society
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    • 제47권1호
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    • pp.74-77
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    • 2010
  • Rhino-orbital-cerebral (ROC) mucormycosis is an uncommon, acute and aggressive fungal infection. It remains a challenging problem to clinicians despite aggressive debridement surgery and antifungal therapy. The authors describe a case of ROC mucormycosis with pericranial abscess occurring in a female patient with uncontrolled diabetes mellitus. The infection initially developed in the right-sided nasal sinus and later progressed through the paranasal sinuses with the invasion of the peri-orbital and frontotemporal region, due to the delayed diagnosis and treatment. Numerous non-septate hyphae of the zygomycetes were identified by a punch biopsy from the nasal cavity and by an open biopsy of the involved dura. The patient was treated successfully with extensive debridement of her necrotic skull and surrounding tissues, drainage of her pericranial abscess and antifungal therapy, including intravenous amphotericin B for 61 days and oral posaconazole for the following 26 days. She returned to a normal life and has had no recurrence since the end of her treatment 15 months ago.

Analysis of the Formation of Protoplasts and Regeneration of Cells in Phycomyces blakesleeanus

  • Joe, Fukui;Choi, Kwan-Sam;Atsushi Miyazaki;Tamotsu Ootaki;Taneaki Oikawa
    • Journal of Microbiology and Biotechnology
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    • 제11권1호
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    • pp.72-78
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    • 2001
  • It is possible ot prepare protoplasts of the zygomycete fungus, Phycomyces blakesleeanus, by digesting the cell wall of spore germlings with commercially available chitinase and chitosanase. However, the cells without any cell walls immediately form large aggregates, and thus, it is difficult to isolate the individually separated protoplasts. Inherent problem with the formation of aggregates in preparing protoplasts could be solved by the use of bovine serum albumin (BSA). As a result, we were able to prepare a large number of single protoplsts quickly and easily. We took time-lapse photomicrographs of the formation of protoplasts, and found that there were certain regions of the cell wall of spore germlings that were sensitive to chitinase and chitosanase, although the cell wall of the original spores is known to be insensitive to these enzymes. There are two kinds of cell walls on a spore germling; one with a bound wheat germ agglutinin (WGA), and the other a bound concanavalin A (ConA). Furthermore, only cells with walls which had bound WGA were able to regenerate, while those with walls with bound ConA were not able to regenerate.

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복숭아혹진딧물에서 발견된 국내 미기록 곤충병원성 곰팡이 Entomophthora planchoniana에 관한 보고 (Entomophthora planchoniana Cornu (Zygomycetes: Entomophthoraceae), the First Observed Pathogen of the Green Peach Aphid Myzus persicae in Korea)

  • 윤철식;성기호;이건형;박현수;이정운
    • 한국균학회지
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    • 제26권3호통권86호
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    • pp.403-406
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    • 1998
  • 국내 미기록 곤충병원성 곰팡이, Entomophthora planchoniana를 1998년 6월 2일 전북 군산 아욱 재배지의 복숭아혹진딧물에서 발견하였다. 이에 국내에서 처음으로 E. planchoniana를 보고하며, 형태적 특징을 기재한다. 또한 이 균의 가장 중요한 분류학적 특징은 Entomophthora속 곰팡이 중 진딧물에 기생하는 유일한 종이며, 1차포자는 $4{\sim}6$개의 핵을 지닌 종모양 이였으며 원형질로 감싸져 있었다.

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