• Title/Summary/Keyword: Zhou-li

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Research Progress on the Livin Gene and Osteosarcomas

  • Li, Cheng-Jun;Cong, Yu;Liu, Xiao-Zhou;Zhou, Xing;Shi, Xin;Wu, Su-Jia;Zhou, Guang-Xin;Lu, Meng
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.8577-8579
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    • 2014
  • Osteosarcoma is a common malignant tumor of bone, but mechanisms underlying its development are still unclear. At present, it is believed that the inhibition of normal apoptotic mechanisms is one of the reasons for the development of tumors, so specific stimulation of tumor cell apoptosis can be considered as an important therapeutic method. Livin, as a member of the newly discovered inhibitor of apoptosis proteins (IAPs) family, has specifically high expression in tumor tissues and can inhibit tumor cell apoptosis through multiple ways, which can become a new target for malignant tumor treatment (including osteosarcoma) and might of great significance in the clinical diagnosis of tumors and the screening of anti-tumor agents and carcinoma treatment.

Study on economic performances of multi-span suspension bridges part 2: parametric study

  • Zhang, Li-Wen;Xiao, Ru-Cheng;Sun, Bin;Jiang, Yang;Zhang, Xue-Yi;Zhuang, Dong-Li;Zhou, Yun-Gang;Tu, Xue
    • Structural Engineering and Mechanics
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    • v.47 no.2
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    • pp.287-305
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    • 2013
  • Economic performances of consecutive multi-span suspension bridges are studied. The material amount and cost estimation formulas of the bridges have been derived in the part 1 of the study. A parametric study is carried out based on the formulas for investigating the different factors' effect on the bridge cost. The factors include the bridge sag, the bridge span, the bridge foundation and the environment condition, etc. Then, an economical layout of the bridges is proposed for different conditions. Lastly, a selection of suspension bridge types is discussed based on the economy of bridges.

A Digital Self-Sustained Phase Shift Modulation Control Strategy for Full-Bridge LLC Resonant Converters

  • Zheng, Kai;Zhou, Dongfang;Li, Jianbing;Li, Li;Zhao, Yujing
    • Journal of Power Electronics
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    • v.16 no.3
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    • pp.915-924
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    • 2016
  • A digital self-sustained phase shift modulation (DSSPSM) strategy that allows for good soft switching and dynamic response performance in the presence of step variations is presented in this paper. The working principle, soft switching characteristics, and voltage gain formulae of a LLC converter with DSSPSM have been provided separately. Furthermore, the method for realizing DSSPSM is proposed. Specifically, some key components of the proposed DSSPSM are carefully investigated, including a parameter variation analysis, the start-up process, and the zero-crossing capture of the resonant current. The simulation and experiment results verify the feasibility of the proposed control method. It is observed that the zero voltage switching of the switches and the zero current switching of the rectifier diodes can be easily realized in presence of step load variations.

Efficient Anonymous Broadcast Encryption with Adaptive Security

  • Zhou, Fu-Cai;Lin, Mu-Qing;Zhou, Yang;Li, Yu-Xi
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.11
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    • pp.4680-4700
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    • 2015
  • Broadcast encryption is an efficient way to distribute confidential information to a set of receivers using broadcast channel. It allows the broadcaster to dynamically choose the receiver set during each encryption. However, most broadcast encryption schemes in the literature haven't taken into consideration the receiver's privacy protection, and the scanty privacy preserving solutions are often less efficient, which are not suitable for practical scenarios. In this paper, we propose an efficient dynamic anonymous broadcast encryption scheme that has the shortest ciphertext length. The scheme is constructed over the composite order bilinear groups, and adopts the Lagrange interpolation polynomial to hide the receivers' identities, which yields efficient decryption algorithm. Security proofs show that, the proposed scheme is both secure and anonymous under the threat of adaptive adversaries in standard model.

Comparison of the effect of lithium bentonite and sodium bentonite on the engineering properties of bentonite-cement-sodium silicate grout

  • Zhou, Yao;Wang, Gui H.;Chang, Yong H.
    • Advances in concrete construction
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    • v.9 no.3
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    • pp.279-287
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    • 2020
  • This paper focuses on the engineering properties of Bentonite-Cement-Sodium silicate (BCS) grout, which was prepared by partially replacing the ordinary Portland cement in Cement-Sodium silicate grout with lithium bentonite (Li-bent) and sodium bentonite (Na-bent), respectively. The effect of different Water-to-Solid ratio (W/S) and various replacement percentages of bentonite on the apparent viscosity, bleeding, setting time, and early compressive strength of BCS grout were investigated. The XRD method was used to detect its hydration products. The results showed that both bentonites played a positive role in the stability of BCS grout, increased its apparent viscosity. Na-bent prolonged the setting time of BCS, while 5% of Li-bent shortened the setting time of BCS. The XRD analysis indicated that the hydration products between the mixture containing Na-bent and Li-bent did not differ much. Using bentonite as supplementary cementitious material (SCM) to replace partial cement is a promising way to cut down on carbon dioxide emissions and to produce low-cost, eco-friendly, non-toxic, and water-resistant grout. In addition, Li-bent was superior to Na-bent in improving the strength and the thickening of BCS grouts.

Recent Development in the Rate Performance of Li4Ti5O12

  • Lin, Chunfu;Xin, Yuelong;Cheng, Fuquan;Lai, Man On;Zhou, Henghui;Lu, Li
    • Applied Science and Convergence Technology
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    • v.23 no.2
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    • pp.72-82
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    • 2014
  • Lithium-ion batteries (LIBs) have become popular electrochemical devices. Due to the unique advantages of LIBs in terms of high operating voltage, high energy density, low self-discharge, and absence of memory effects, their application range, which was primarily restricted to portable electronic devices, is now being extended to high-power applications, such as electric vehicles (EVs) and hybrid electrical vehicles (HEVs). Among various anode materials, $Li_4Ti_5O_{12}$ (LTO) is believed to be a promising anode material for high-power LIBs due to its advantages of high working potential and outstanding cyclic stability. However, the rate performance of LTO is limited by its intrinsically low electronic conductivity and poor $Li^+$ ion diffusion coefficient. This review highlights the recent progress in improving the rate performance of LTO through doping, compositing, and nanostructuring strategies.

The Synergism of Human Lactobacillaceae and Inulin Decrease Hyperglycemia via Regulating the Composition of Gut Microbiota and Metabolic Profiles in db/db Mice

  • Peifan Li;Tong Tong;Yusong Wu;Xin Zhou;Michael Zhang;Jia Liu;Yongxin She;Zuming Li;Yongli Li
    • Journal of Microbiology and Biotechnology
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    • v.33 no.12
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    • pp.1657-1670
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    • 2023
  • This study aimed to evaluate the effects of Limosilactobacillus fermentum and Lactiplantibacillus plantarum isolated from human feces coordinating with inulin on the composition of gut microbiota and metabolic profiles in db/db mice. These supplements were administered to db/db mice for 12 weeks. The results showed that the Lactobacillaceae coordinating with inulin group (LI) exhibited lower fasting blood glucose levels than the model control group (MC). Additionally, LI was found to enhance colon tissue and increase the levels of short-chain fatty acids. 16S rRNA sequencing revealed that the abundance of Corynebacterium and Proteus, which were significantly increased in the MC group compared with NC group, were significantly decreased by the treatment of LI that also restored the key genera of the Lachnospiraceae_NK4A136_group, Lachnoclostridium, Ruminococcus_gnavus_group, Desulfovibrio, and Lachnospiraceae_UCG-006. Untargeted metabolomics analysis showed that lotaustralin, 5-hydroxyindoleacetic acid, and 13(S)-HpODE were increased while L-phenylalanine and L-tryptophan were decreased in the MC group compared with the NC group. However, the intervention of LI reversed the levels of these metabolites in the intestine. Correlation analysis revealed that Lachnoclostridium and Ruminococcus_gnavus_group were negatively correlated with 5-hydroxyindoleacetic acid and 13(S)-HpODE, but positively correlated with L-tryptophan. 13(S)-HpODE was involved in the "linoleic acid metabolism". L-tryptophan and 5-hydroxyindoleacetic acid were involved in "tryptophan metabolism" and "serotonergic synapse". These findings suggest that LI may alleviate type 2 diabetes symptoms by modulating the abundance of Ruminococcus_gnavus_group and Lachnoclostridium to regulate the pathways of "linoleic acid metabolism", "serotonergic synapse", and" tryptophan metabolism". Our results provide new insights into prevention and treatment of type 2 diabetes.