• 대한한의학원전학회지
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• 제18권2호통권29호
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• pp.205-212
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• 2005

Zhang Zi-He is one of the Jin&Yuan's four masters, and he used Dong-Xia method well, as well as he is one a medical man who contributed to the development of the medicine. He valued the pathogen. He recognized that the pathogen is a great cause of an attack of a disease, so, first, we have to get rid of pathogen, and it makes the Vital essence and energy recovered. He said, we have to get rid of the pathogen thouroughly. He used 'Wei Ci'-using fei zhen and densely puntuating many times and bleeding much, so the pathogen can't remain. He said if we bleed, it is same as the sweating. And about ${\ulcorner}Nei Jing{\lrcorner}$'s meaning, he said that bleeding is same as sweating and after bleeding, diaphoresis is not required, but it is good to bleed after sweating. He said that we removeing the fire and we can circulate Qi and blood. He set count on the body's circulation of our body, and it is the great cause of a disease. So, He quoted the ${\ulcorner}Nei Jing{\lrcorner}$'s sayings, and emphasized the importane of the circulation of qi and blood. And this Zhang Zi-He's way is in relation with 'Liu He Jian's fire and heat theory.

• 대한한방소아과학회지
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• 제19권2호
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• pp.51-68
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• 2005

Objective : Rumenshiqin(儒門事親) was compiled by Zhang Zi Huo(張子和) of the Jin(金) Dynasty of China. He invented unique medical theory and treatment such as three excretive methods(perspiratory, vomitory and purgative therapy). The aim of this study was to make the best use of the therapeutic theory of Rumenshiqin(儒門事親) connected with pediatrics. Methods: We conducted literature search in detail for contents of Rumenshiqin(儒門事親) and reviewed various kinds of books. Results : Zhang Zi Huo(張子和) recognized that children had pure-yang bodies(純陽之體) and emphasized that children need to prevent heat-stagnation(鬱熱) and asthenic yin(損陰). He instructed that a principle of raising such as wearing thin clothes, eating fresh food, harboring little desire and little anger, and taking temperate medicine. He described that pathogenic factors were mistake of rearing, misuse of medicine, exogenous factor, and excessive emotion. Conclusion : According to the above results, it is concluded that his therapeutic theory should be used at present.

• 한국도서관정보학회지
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• 제27권
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• pp.171-209
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• 1997

The results of the study can be summarized as follows. The Shu-mu Da-wen was selected and compiled by Zhang Zhi Dong at the end of Qing Dynasty as a reading list for students preparing for the state examination and for the purpose of choosing the best from several versions. Whether it was compiled and edited by Zhang was in dispute. But it is almost certain that Zhang was the main editor because Shu-mu Da-wen showed his political, educational and scientific thoughts and knowledge distinctively. The followings are characteristics of Shu-mu Da-wen being compared with Si-ku Quan-shu Zong-mu Ti-yao. 1. In Jing-bu, the Confucian classics are divided into Zheng-jing Zheng-zhu and 'Lie-chao Jing-zhu Jing-shuo Jing-ben kao-zheng. Zheng-shi lei is divided into Zheng-shi fen he ke ben and Zheng-shi zhu bu biao pu kao-zheng. It is the special sorting method to include Du-ben lei in Jing-bu and Chu xue du-ben in Bie-lu in order to provide first learners for reading order. 2. Shi-bu included Gu-shi newly and Di-li lei is divided into Gu Di-li and Jin di-li in Shi-bu. Tian-wen Suan-fa lei is divided into Zhong-fa and Xi-fa in Zi-bu. Zhang distinguished between old books and contemporary ones to find out the origin and include newly published books in the East and the West. 3. Zhou-Qin zhu-zi is newly added to Zi-pu. In Ji-pu, Bie-ji and Zong-ji are categorized according to their style and period respectively. This show the new sorting method which added classifying system concerning academic development. It is the prominent feature in the compiling system to make Bie-lu and Cong-shu respective chapters. With those characteristics the Shu-mu Da-wen had been edited and published several times. It had a wide effect not only on compiling methods of cataloging afterwards and but also on classification systems before decimal classification was introduced in China.

• 대한한의학원전학회지
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• 제25권3호
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• pp.127-147
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• 2012

Objective : Methods of Jang Cong-zheng's treatment related to his theories include of promoting the sweating-vomiting-purgation(汗吐下三法), prickling-bleeding method(瀉血療法), and emotional therapy(情志療法). He succeeded Liu wan-su(劉完素) as promoter of fire-heat pattern theory(火熱論), thereby emphasizing six qi(六氣), especially fire(火) and dampness(濕), as pathogens. He suggested that physician should treat patients whose diseases occurred due to fire(火) and dampness(濕) with promoting the sweating(汗)-vomiting(吐)-purgation(下) methods, which would remove pathogen qi(邪氣) and help circulation of qi and blood, therefore getting them back healthy qi(正氣). Method : I will try to describe the Jang Cong-zheng's treatment in "Ru-Men-Shi-Qin", and I would like to explain the sweating-vomiting-purgation(汗吐下三法), prickling-bleeding method(瀉血療法), and emotional therapy(情志療法). Result : For emotional diseases, he suggested that most should be caused by heart fire(心火) so they should be treated with methods of suppressing heart fire and medication would be using cool and cold herbal drugs which lead to clear heart fire. Conclusion : Theories of Zhang zi-he(張子和) can be applied to nurturing for modern world maintaining and improving health by his care methods. People these days suffer usually from excess intake or unbalanced diet problem, so wastes matter and pathogenic qi can be driven out of the human body by applying the sweating-vomiting-purgation methods. His medical theories could contribute to modernization of traditional medicine this way.

• 동국한의학연구소논문집
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• 제6권1호
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• pp.1-34
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• 1997

동양의학에서 "상한론(傷寒論)"의 발전은 대체로 삼단계(三段階)의 과정을 거쳤으나 "삼강정립(三綱鼎立)"설이 대세를 이루고 있었다. 이러한 관점에 대항하여 변증논치규율(辯證論治規律)을 연구한 학파(學派)가 나타나게 되었는데 우이(尤怡)가 그 중 한사람이다. 우이(尤怡)의 생애(生涯), 저서(著書), 학술사상(學術思想) 및 후세에 미친 영향 등을 조사하고 특히 "상한론(傷寒論)"을 안법류증(按法類?)하여 육경(六經)에 따른 정치법(正治法) 권변법(權變法) 알선법(斡旋法) 구역법(救逆法) 유병법(類病法) 명변법(明辨法) 잡치법(雜治法) 등의 치법(治法)에 대하여 연구하여 보고하는 바이다.

• 대한한의학원전학회지
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• 제32권4호
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• pp.91-107
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• 2019

Objectives : The purpose of this paper is to study how medical experts understood 'Specially Selecting Yangming' for clinical application. Methods : After collecting medical texts related to 'Specially Selecting Yangming', its meaning and clinical application were examined thoroughly. Results : 1. The meaning of 'Specially Selecting Yangming' was identified in different ways according to the meaning of 'Yangming.' It was perceived as Stomach, Yangming meridian, Stomach meridian of Foot Yangming, Spleen and Stomach, Intestine and Stomach by medical experts. 2. Chen Wu-ze and Liu Wan-su understood Wei disease as a form of consumption, and regarded 'Specially Selecting Yangming' as tonifying Yangming while Zhang Zi-he put emphasis on Communicating Stomach Qi(胃氣) through vomiting or purgation. Sun Yi-kui insisted on applying it as a precaution. 3. Li Dong-yuan emphasized the cause of Wei disease to be Damp-Heat in the Summer and suggested Qingshuyiqitang and Qingzaotang as remedy. 4. Zhu Zhen-heng's Purging the South and Reinforcing the North is a more fundamental way of treating Wei disease by stimulating the Water-Fire Axis. Conclusions : Through a diachronic study of 'Specially Selecting Yangming' and its remedy, most medical experts regarded 'Specially Selecting Yangming' as tonifying Yangming, but tonifying Liver and Kidney was thought to be a more fundamental treatment.

• 대한한의학원전학회지
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• 제18권4호통권31호
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• pp.1-14
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• 2005

Zhu Dan Xi's name is ZhenHeng(震亨) and was also called by the title of YanXiu(彦修). Early in his life, he started to study JuZiYe(擧子業), and went on to study DaoDeXingMingXue(道德性命學) under the teachings of XueQian(許謙), who as one of fourth generation disciple of ZhuZi(朱子) was teaching in BaHuaShan(八華山). His well-known literary works are ${\ulcorner}$JuFangFaHui(局方發揮)${\lrcorner}$, ${\ulcorner}$GeZhiYuLun${\lrcorner}$, ${\ulcorner}$ShangHanBianYi(傷寒辨疑)${\lrcorner}$, ${\ulcorner}$BenCaoYanYiBuYi(本草衍義補遺)${\lrcorner}$, ${\ulcorner}$WaiKeJingYaoXinLun(外科精要新論)${\lrcorner}$. Zhu Dan Xi learnt the studies of Liu(劉), Zhang(張), Li(李) from LouZhiTi(羅知悌) and adopted the advantages and abolished disadvantages from it. The southern district being low and damp, which also leads to a geographical condition with a lot of ShiReXiangHuo(濕熱相火) disease and with the social background of people exhausting their QingYu(情欲) and damaging QLXie(氣血), he came out with the theory of 'YangYouYuYinBuZu(陽有餘陰不足)', 'XiangHuo(相火)' and became a well renowned expert in diagnosis and treatment of QiXieTanYuHuo(氣血痰鬱火). As a result, the writer has performed a research based on Liu's works and related theories, GuWuZhiZhi theory, the understanding of TaiJiZhiLi(太極之理), the inner meaning of YinYang and YouYuBuZu(redundancy-and-deficit), YinYangDongJingGuan, physiology and pathology, the medical reason of lust damaging QingYuYangYin and YangSheng(養生)(preservation of health), which are the main medical theory of ZhuDanXi, comments of later generations and is reporting the outcome.

• Asian Pacific Journal of Cancer Prevention
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• 제13권6호
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• pp.2485-2489
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• 2012

Purpose: Notch is an important signaling pathway that regulates cell fate, stem cell maintenance and the initiation of differentiation in many tissues. It has been reported that activation of Notch-1 contributes to tumorigenesis. However, whether Notch signaling might have a role in chemoresistance of prostate cancer is unclear. This study aimed to investigate the effects of Notch-1 silencing on the sensitivity of prostate cancer cells to docetaxel treatment. Methods: siRNA against Notch-1 was transfected into PC-3 prostate cancer cells. Proliferation, apoptosis and cell cycle distribution were examined in the presence or absence of docetaxel by MTT and flow cytometry. Expression of $p21^{waf1/cip1}$ and Akt as well as activation of Akt in PC-3 cells were detected by Western blot and Real-time PCR. Results: Silencing of Notch-1 promoted docetaxel induced cell growth inhibition, apoptosis and cell cycle arrest in PC-3 cells. In addition, these effects were associated with increased $p21^{waf1/cip1}$ expression and decreased Akt expression and activation in PC-3 cells. Conclusion: Notch-1 promotes chemoresistance of prostate cancer and could be a potential therapeutic target.

• Steel and Composite Structures
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• 제46권6호
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• pp.773-791
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• 2023

Connections with damage concentrated to pre-selected components can enhance seismic resilience for moment resisting frames. These pre-selected components always yield early to dissipate energy, and their energy dissipation mechanisms vary from one to another, depending on their position in the connection, geometry configuration details, and mechanical characteristics. This paper presents behaviour insights on two types of beam-to-beam connections that the angles were designed as energy dissipation components, through the results of experimental study and finite element analysis. Firstly, an experimental programme was reviewed, and key responses concerning the working mechanism of the connections were presented, including strain distribution at the critical section, section force responses of essential components, and initial stiffness of test specimens. Subsequently, finite element models of three specimens were established to further interpret their behaviour and response that were not observable in the tests. The moment and shear force transfer paths of the composite connections were clarified through the test results and finite element analysis. It was observed that the bending moment is mainly resisted by axial forces from the components, and the dominant axial force is from the bottom angles; the shear force at the critical section is primarily taken by the slab and the components near the top flange. Lastly, based on the insights on the load transfer path of the composite connections, preliminary design recommendations are proposed. In particular, a resistance requirement, quantified by a moment capacity ratio, was placed on the connections. Design models and equations were also developed for predicting the yield moment resistance and the shear resistance of the connections. A flexible beam model was proposed to quantify the shear resistance of essential components.

• International Journal of Internet, Broadcasting and Communication
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• 제16권1호
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• pp.106-123
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• 2024

This article takes the talk show "Beast Town" as an example to introduce the overall technical solution, technical difficulties and countermeasures for the combination of cartoon virtual characters and virtual studio technology, providing reference and experience for the multi-scenario application of digital humans. Compared with the live broadcast that combines reality and reality, we have further upgraded our virtual production technology and digital human-driven technology, adopted industry-leading real-time virtual production technology and monocular camera driving technology, and launched a virtual cartoon character talk show - "Beast Town" to achieve real Perfectly combined with virtuality, it further enhances program immersion and audio-visual experience, and expands infinite boundaries for virtual manufacturing. In the talk show, motion capture shooting technology is used for final picture synthesis. The virtual scene needs to present dynamic effects, and at the same time realize the driving of the digital human and the movement with the push, pull and pan of the overall picture. This puts forward very high requirements for multi-party data synchronization, real-time driving of digital people, and synthetic picture rendering. We focus on issues such as virtual and real data docking and monocular camera motion capture effects. We combine camera outward tracking, multi-scene picture perspective, multi-machine rendering and other solutions to effectively solve picture linkage and rendering quality problems in a deeply immersive space environment. , presenting users with visual effects of linkage between digital people and live guests.