• Title/Summary/Keyword: Zanthoxylum piperitum

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Antifungal Activity of Plant Extracts against Pityrosporum ovale and Candida albicans (식물 추출물의 Pityrosporum ovale 및 Candida albicans에 대한 항진균 활성)

  • Ryu, Shi-Yong;Kim, Seong-Deog;Jang, So-Young
    • Korean Journal of Pharmacognosy
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    • v.34 no.4 s.135
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    • pp.303-307
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    • 2003
  • For the purpose of searching for the new antifungal agent from the plant origin, we have examined twenty seven species of medicinal plants for the antifungal activity against Candida albicans and Pityrosporum ovale. The whole MeOH extract of each plant material and the n-hexane and EtOAc fractions were evaluated individually for the antifungal activity. Among the test materials, the fractions from the root bark of Zanthoxylum schinifolium, Zanthoxylum piperitum and Citrus unshiu showed significant antifungal activities in a dose dependent manner against Pityrosporum ovale and Candida albicans, respectively.

Application of the Extract of Zanthoxylum piperitum DC to Manufacturing Eco-friendly Antimicrobial Interior Fabric Blind Materials (초피 추출물을 이용한 친환경 항균 실내 직물 블라인드 소재 개발)

  • Xie, Li Rui;Jun, Do Youn;Park, Ju Eun;Kwon, Gi Hyun;Cho, Bonggeun;Park, Hyun Woo;Lee, Chang Woo;Kim, Chang Young;Jung, Hyo-Il;Kim, Young Ho
    • Journal of Life Science
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    • v.26 no.8
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    • pp.936-942
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    • 2016
  • As the incidence of environmental diseases is increasing due to harmful environmental factors, there is a rising interest in developing eco-friendly materials for housing. In this study, we sought to develop antimicrobial interior fabric blind materials by employing ethanol extract of a medicinal plant Zanthoxylum piperitum DC. As determined by the disc diffusion method, the zones of inhibition of the pericarp ethanol extract at a concentration of 5 mg/disc against Klebsiella pneumoniae, Staphylococcus aureus, and Streptococcus mutans were 13.5±1.5 mm, 14.0±0.5 mm and 15.0±0.1 mm, respectively, whereas the leaf ethanol extract (5 mg/disc) against K. pneumoniae, S. aureus, and S. mutans were 12.8± 0.3 mm, 13.5±1.0 mm, and 12.0±0.1 mm, respectively. The IC50 of the leaf ethanol extract against K. pneumoniae, S. aureus and S. mutans were about 0.5 mg/ml, 0.1 mg/ml and 1.0 mg/ml respectively. To examine whether the leaf ethanol extract possessing antibacterial activity of Z. piperitum DC can be applicable to production of antimicrobial fabric blind materials, the fabrics treated with either 1.0% or 2.0% of the leaf ethanol extract were tested for antibacterial activity against K. pneumoniae and S. aureus using International Standard Fabrics Test Method. The results indicate that the fabric treated with the ethanol extract of Z. piperitum DC possesses an excellent antimicrobial activity against both pathogenic bacteria. These results suggest that Z. piperitum DC may be applicable to producing functional fabrics which are effective in reducing the harmful bacterial factors in indoor environments.

Anti-HIV and Antihepatotoxic Constituents from Medicinal Plant Resources

  • Park, Jong-Cheol;Park, Ju-Gwon;Hur, Jong-Moon;Hwang, Young-Hee;Jung, Deuk-Young
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2001.11a
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    • pp.68-73
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    • 2001
  • Medicinal plants were screened for the inhibitory effects on human immunodeficiency virus type 1 pretense Of the extracts tested, the strong inhibitory effects were observed in the acetone extracts of the pericarp of Camellia japonica. Camelliatannin H from the pericarp of C. japonica showed a potent inhibitory activity on HIV- 1 pretense. Effects of the extract and compound from leaves of Zanthoxylum piperitum on the enzyme activities were investigated in the liver of bromobenzene-treated rats. The methanol extract and protocatechuic acid isolated from Z. piperitum reduced the activity of aniline hydroxylase that increased by bromobenzene, while did not affect the activities of aminopyrin N-demethylase and glutathione S-transferase The extract and protocatechuic acid recovered significantly the activity of epoxide hydrolase decreased by bromobenzene.

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Effect of Zanthoxylum piperitum Extract on Human Skin Protection from UVB by Regulation of COP1 and PPAR-α (초피나무 열매 추출물의 COP1 및 PPAR-α 조절을 통한 자외선에 대한 피부 보호 효과)

  • Kim, Yun-Sun;Kim, Yumi;Lee, Sanghwa
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.42 no.4
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    • pp.393-401
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    • 2016
  • Ultraviolet (UV) irradiation from the sun is the primary environmental factor that causes skin damages including skin cancer and premature skin aging. Because, even the most powerful sunscreen can't always afford enough protection, it is necessary to enhance the defensive power of skin against UV. Recently, constitutive photomorphogenic protein-1 (COP1) has shown to contribute to the regulation of UVB response of keratinocytes. In this study, we represent that COP1 and its associated protein, de-etiolated 1 (DET1), might participate in photoaging process in human skin as Arabidopsis COP1 does sun-protective function in plants. After UVB irradiation, the decrease of COP1 and DET1 mRNA expression was followed by the increase of c-Jun total protein. Moreover, transfection with DNA vectors expressing COP1 and DET1 down-regulated the c-Jun total protein. We found that Zanthoxylum piperitum extract (ZE) up-regulated the expression of COP1 and DET1 on human keratinocytes, and inhibited the expression of MMP1 which is one of the genes regulated by c-Jun signal. In addition, ZE has been reported to stimulate PPAR-${\alpha}$ and strengthen the skin barrier. We found that ZE decreased the UVB-induced IL-6 and IL-8 in NHEK cells. In human study, ZE protected skin against UV-B induced erythema and erythema-induced pigmentation. These results indicate that ZE could be useful for the protection against the adverse effects of UV irradiation through various mechanisms.

Volatile Flavor Components of Wild Chopi (Zanthoxylum piperitum De Candolle) Leaf (야생 초피(Zanthoxylum piperitum De Candolle)잎의 향기성분)

  • 박준희;차원섭;오상룡;조영제;이원영
    • The Korean Journal of Food And Nutrition
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    • v.13 no.5
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    • pp.483-489
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    • 2000
  • Wild Chopi leaves were harvested near Chounghwa Mt. Sangju city in Kyungpook province. Chopi leaves were dried naturally and crushed with and without blanching. From mechanical analysis(GC). fifty five peaks were identified as volatile materials in no blanching leaf. Among the fifty five peaks, twenty three peaks were identified as hydrocarbones(dodecane, sabinene, myrcene etc.), ten peaks as alcohols (isobutylalcohol. cis-pentenol, 1-pentenol, 1-penten-3-ol etc.), seven peaks as aldehydes (3-methylbua-tanal, hexanal, 2,6-dimethyl hept-5-al etc.), four peaks as ketones(3-hydroxy-2-butanone, 2-nonanone, 2-undecanone, 2-tridecanone) and six peaks as esters ( cis-3-hexenyl acetate, linalyl acetate. citronellyl acetate, nervy acetate etc.). Other peaks were founded as 3-cyano-2,5-dimethylpyrazine, dimethyl sulfide, chloroform, 1,8 cineole. Thirty five peaks were identified as volatile materials in blanching leaf. Twenty peaks were identified as hydrocarbones(1,1-oxybis-ethane, $\alpha$-pinene, camphene. myrcene, $\beta$-phellan-drene, $\beta$-caryophyllene etc.), as alcohol(L-linalool, (-)-isopulgerol, $\alpha$-terpineol. citronellol etc.), as aldehydes(nonanal, citronellal), as ketones(2-undecanone, 2-tridecanone etc.) and as esteres(citronellyl acetate. cis-3-hexenyl acetate, neryl acetate etc.). Other peaks were found as 3-cyano-2,5-dimethyl-pyrazine. The amount of volatile materials such as $\alpha$-pinene, myrcene, $\beta$-phellanderene, L-linalool, citronellal, citronellyl acetate, $\beta$-caryophyllene were detected abundantly among the volatile materials.

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Effect of $GA_3$, Kinetin and Physical Treatment on the Seed Germination of Zanthoxylum piperitum A.P. DC. ($GA_3$, Kinetin 및 물리적 처리가 초피나무 종자의 발아에 미치는 영향)

  • Kim, Se-Jong;Shin, Jong-Hee;Kim, Ki-Jae;Park, So-Deug;Choi, Boo-Sull;Kim, Kil-Ung
    • Korean Journal of Medicinal Crop Science
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    • v.5 no.1
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    • pp.43-48
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    • 1997
  • This study was conducted to improve germination ratio of Zanthoxylum piperitum A.P. DC. seeds. Stratification for 60 days after scarification of seed with sand was germination percentage to 5.4% and $GA_3$, 50ppm for 24 hrs after scarification of seed with sand showed 8.9%. Soaking the seeds in $GA_3$, 50ppm for 24 hrs after 40 to $70^{\circ}C$ hot water treatment for 10 minutes showed low germination of 4.4%. Based on $H_2SO_4$, NaOH and $HNO_3$, treatments, germination percentage did not improve at all regardless of soaking time. The highest germination of 91.1% was observed when seed was soaked in $GA_3$ 100ppm for 48 hrs after stratification for 60 days at $4^{\circ}C$. Kinetin treatment at 50ppm for 24 hrs had the greatest germination percentage of 31.7% but it did not improve germination ratio compared to $GA_3$ treatment.

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